Cytogenetic abnormalities in serous papillary adenocarcinoma of the ovary.

Abstract:

PURPOSE OF INVESTIGATION:Epithelial ovarian tumors are usually mucinous or serous type, affecting nearly 1% of women during their lifetime. They may be regarded as benign, borderline or invasive according to pathological examination. Karyotypes of the tumor provide critical information about both the genetic predisposition and the stage of the tumor. We aimed to investigate the correlation between karyotype findings and the stage of the serous papillary tumors of the ovary. METHODS:Tissue cultures were set up from 15 serous papillary adenocarcinoma samples of different stages and examined cytogenetically. RESULTS:The most common chromosome abnormalities included both numerical and structural abnormalities of chromosomes 1, 3,6,7,8, 11, 21, 22 and X. CONCLUSION:Karyotypes became more complex, as expected, with the later stages.

journal_name

Eur J Gynaecol Oncol

authors

Sahin I,Yilmaz Z,Sahin FI

keywords:

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

585-6

issue

5

eissn

0392-2936

issn

2709-0086

journal_volume

25

pub_type

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