Abstract：
OBJECTIVES:Although the direct cause for periodontitis is oral bacterial infection, its progression depends upon genetic and environmental factors. Smoking, one of the environmental factors, is a risk factor for the development and severity of periodontitis. Therefore, individual susceptibility to periodontitis may be influenced by the polymorphisms of genes coding for enzymes metabolizing tobacco-derived substances. The object of this study is to investigate roles of genetic polymorphisms of these metabolizing enzymes in the risk for periodontitis. MATERIAL AND METHODS:We investigated three important enzymes: cytochrome P450 (CYP) 1A1, CYP2E1 and glutathione S-transferase (GST) M1, involved in the metabolic activation and detoxification of tobacco-derived substances. The prevalence of the polymorphisms of these genes was examined in 115 patients with periodontitis as well as in 126 control subjects. RESULTS:Significantly increased risk for periodontitis was observed for subjects with the polymorphic CYP1A1 m2 allele (odds ratio (OR)=2.3, 95% confidence interval (CI)=1.2-4.4). A significant risk increase for periodontitis associated with the GSTM1 allele was observed (OR=2.1, 95% CI=1.3-3.6). However, no association was observed between the CYP2E1 Pst1 polymorphism and risk for periodontitis (OR=1.3, 95% CI=0.6-2.5). CONCLUSION:These results suggest that the GSTM1 and CYP1A1 polymorphisms may play an important role in risk for periodontitis.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Kim JS,Park JY,Chung WY,Choi MA,Cho KS,Park KKdoi
10.1111/j.1600-051X.2004.00587.xkeywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
959-64issue
11eissn
0303-6979issn
1600-051Xpii
CPE587journal_volume
31pub_type
杂志文章abstract：:The present review concerns the effect on plaque and gingivitis of some antibacterial dentifrices. The difficulties of including cationic agents in conventional dentifrice formulations are briefly discussed. The focus is on 2 recently introduced dentifrices with triclosan as the active ingredient. One aims at providin...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,评审
doi：10.1111/j.1600-051x.1991.tb02318.x
更新日期：1991-07-01 00:00:00
abstract：AIM:To evaluate the clinical efficacy of subgingival ultrasonic instrumentation irrigated with essential oils (EOs) of residual periodontal pockets. MATERIAL AND METHODS:Sixty-four individuals with chronic periodontitis were invited to participate in this randomized, double-blind, parallel, and placebo-controlled clin...
journal_title：Journal of clinical periodontology
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abstract：:This study analysed data on periodontal reasons for tooth extractions, obtained from 52 dentists practising general dentistry in Singapore. The results revealed that, out of 2172 teeth extracted from 1276 patients, 35.8% were lost due to periodontal disease and 35.4% due to caries. Extraction due to periodontal proble...
journal_title：Journal of clinical periodontology
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abstract：AIM:Vitamin D deficiency is considered to diminish bone regeneration. Yet, raising the serum levels takes months. A topic application of the active vitamin D metabolite, calcitriol, may be an effective approach. Thus, it becomes important to know the effect of vitamin D deficiency and local application on alveolar bone...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12342
更新日期：2015-01-01 00:00:00
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journal_title：Journal of clinical periodontology
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doi：10.1111/j.1600-051X.2005.00746.x
更新日期：2005-11-01 00:00:00
abstract：AIMS:Both, vitamin D3 and human periodontal ligament cells (hPDLCs) possess immunosuppressive properties, but their combined effect on immune cells has never been investigated. Here, we analysed the impact of vitamin D3 on the immunosuppressive properties of hPDLCs towards CD4+ T lymphocytes. MATERIAL AND METHODS:Allo...
journal_title：Journal of clinical periodontology
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doi：10.1111/jcpe.13283
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:Peri-implantitis is common in patients with dental implants. We performed a single-blinded longitudinal randomized study to assess the effects of mechanical debridement on the peri-implant microbiota in peri-implantitis lesions. MATERIALS AND METHODS:An expanded checkerboard DNA-DNA hybridization assay enco...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2010.01561.x
更新日期：2010-06-01 00:00:00
abstract：:Premature exposure of membrane in the oral cavity is considered the most common complication as well as a reason for failure or incomplete success of guided tissue regeneration, as the exposed membrane undergoes plaque accumulation. A method to control, or at least to reduce the bacterial invasion of the membrane allo...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1995.tb00155.x
更新日期：1995-04-01 00:00:00
abstract：OBJECTIVE:To volumetrically evaluate soft tissue changes of different ridge preservation techniques compared to spontaneous healing 6 months after tooth extraction. MATERIALS AND METHODS:In each of 40 patients, one single-rooted tooth was extracted and four treatment modalities were randomly assigned to the following ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jcpe.12246
更新日期：2014-06-01 00:00:00
abstract：AIM:To evaluate whether obesity affects the subgingival microbial composition of patients with periodontal health or chronic periodontitis (CP). MATERIALS AND METHODS:Based on periodontal parameters, body mass index and waist-hip ratio, 166 patients were allocated into one of the following groups: Normal weight (NW) p...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/jcpe.12634
更新日期：2016-12-01 00:00:00
abstract：AIM:the purpose of the present study was to assess the effect of non-surgical periodontal therapy on glycaemic control of type 2 diabetes patients with moderate-to-severe periodontitis. MATERIALS AND METHODS:this was a randomized, controlled clinical trial of patients with type 2 diabetes. A total of 60 patients with ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2010.01652.x
更新日期：2011-02-01 00:00:00
abstract：:Periodontitis (PD) is a chronic inflammatory disease characterised by tissue inflammation and destruction of the associated alveolar bone. It is caused by the colonisation of the bacterial plaque biofilm and the resultant host immune responses in the surrounding periodontal tissues. The pro-inflammatory cytokine IL-17...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,评审
doi：10.1111/jcpe.12238
更新日期：2014-06-01 00:00:00
abstract：:A case of peripheral ameloblastoma on the gingiva of a 50-year-old male is presented. The clinical and histological picture of the lesion is described. The etiology and the dilemma in the differential diagnosis of this peripheral odontogenic tumor is discussed. ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1987.tb00985.x
更新日期：1987-07-01 00:00:00
abstract：BACKGROUND:Only a few dental procedures have been reported to cause life-threatening bleeding. All of these cases followed surgical intervention. MATERIAL AND METHODS:In this paper, we report a case of severe bleeding following non-surgical periodontal procedures in a patient treated with a dual anti-platelet regimen ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2008.01206.x
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:The influence of smoking on the periodontal hemorrhagic responsiveness was investigated in 2 different populations, one exclusively consisting of patients with established periodontal disease, the other of dental hospital admissions in general. MATERIAL AND METHODS:The hemorrhagic responsiveness of the patie...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1034/j.1600-051x.2001.028007680.x
更新日期：2001-07-01 00:00:00
abstract：:The present investigation assessed the feasibility of treating periodontal disease by controlled delivery of antibacterial agents from within periodontal pockets. Tetracycline-filled hollow fibers placed in the gingival sulcus were shown to have a dramatic effect both on the periodontal microflora and clinical manifes...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1979.tb02186.x
更新日期：1979-04-01 00:00:00
abstract：OBJECTIVES:Safety and efficacy of glycine powder air-polishing (GPAP) in removing subgingival biofilm have been previously demonstrated. The hypothesis that GPAP results in less gingival erosion than sodium bicarbonate air-polishing (SBAP) or hand-instrumentation was assessed. MATERIAL AND METHODS:In each of 10 patien...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2007.01195.x
更新日期：2008-04-01 00:00:00
abstract：:It has been reported that the lipid soluble, anti-inflammatory drug triclosan, which is currently used in toothpastes and mouthrinses, may reduce pain. This may be an aspect of the anti-inflammatory effect of triclosan, which probably reduces the production of prostaglandin PGE2. However, triclosan may also exhibit a ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1995.tb00183.x
更新日期：1995-06-01 00:00:00
abstract：:The aim of the study was to evaluate the clinical, radiographical and microbiological outcome after using guided tissue regeneration (GTR) with a bioabsorbable membrane, Resolut. Subjects with bilateral infrabony defects at single rooted teeth were selected. A total of 22 teeth, 2 in each 1 of 7 patients and 4 in 2 pa...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1600-051x.1998.tb02389.x
更新日期：1998-11-01 00:00:00
abstract：:HLA DR4 antigens have been considered as a risk factor in periodontal disease. The aim of this "case control" study was to verify and to provide fuller clarification of such data. "Cases" or patients had to be aged between 20 and 48 years. They presented at least 5 sites spread over several teeth with an attachment lo...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1034/j.1600-051x.1999.260203.x
更新日期：1999-02-01 00:00:00
abstract：:The periodontal status of 85 12-18 year-old Finnish adolescents with insulin-dependent diabetes mellitus (IDDM) and their paired, age- and sex-matched healthy controls was assessed clinically and radiographically. The clinical examination consisted of plaque index, gingival index (GI), retentive calculus index, WHO co...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051x.1989.tb01028.x
更新日期：1989-11-01 00:00:00
abstract：OBJECTIVES:The purpose of this investigation is to describe histologically the undisturbed healing of fresh extraction sockets when compared to immediate implant placement. METHODS:In eight beagle dogs, after extraction of the 3P3 and 4P4, implants were inserted into the distal sockets of the premolars, while the mesi...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2011.01803.x
更新日期：2012-01-01 00:00:00
abstract：AIM:This study aimed to evaluate the clinical effectiveness of the probiotic Lactobacillus reuteri as an adjunct to non-surgical periodontal therapy (NSPT). MATERIALS AND METHODS:A double-blind, paralleled-arm, placebo-controlled and randomized clinical trial was conducted. Probiotics L. reuteri or placebo lozenges we...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/jcpe.13191
更新日期：2019-12-01 00:00:00
abstract：AIM:Anti-cardiolipin (CL) antibodies can be induced in Buerger disease (BD), an inflammatory occlusive disorder affecting peripheral blood vessels, in response to bacteria bearing homology to the TLRVYK peptide of a phospholipid-binding plasma protein beta-2-glycoprotein I. TLRVYK homologies are present in Porphyromona...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2009.01467.x
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE:The objective of this randomized-controlled clinical trial was to evaluate the adjunctive effect of guided tissue regeneration (GTR) using a bioresorbable polylactic acid (PLA) barrier device when combined with autogenous bone grafting in the treatment of deep intra-bony periodontal defects. MATERIAL AND MET...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2007.01160.x
更新日期：2008-01-01 00:00:00
abstract：AIM:To compare the effect of oral infection with Porphyromonas gingivalis or Fusobacterium nucleatum versus infection with both bacteria on mouse periodontal tissues, and to characterize the inflammatory response. MATERIALS AND METHODS:Mice were orally infected with P. gingivalis, F. nucleatum or both. At 42 days post...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1111/j.1600-051X.2009.01393.x
更新日期：2009-05-01 00:00:00
abstract：AIM:The purpose of this study was to assess the initiation and progression of periodontal disease during adult life. MATERIALS AND METHODS:In a 26-year longitudinal investigation of the initiation and progression of chronic periodontitis that started in 1969 and included 565 men of Norwegian middle class, 223 who had ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章
doi：10.1034/j.1600-051x.2003.00399.x
更新日期：2003-10-01 00:00:00
abstract：AIMS:To compare a monotherapy of Er:YAG laser debridement (ERL), wavelength 2940 nm, with mechanical scaling and root planing (SRP) for the treatment of chronic periodontitis using clinical and patient-centred outcomes. METHODS:Twenty-eight participants had two randomly assigned quadrants treated with ERL and two with...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,随机对照试验
doi：10.1111/j.1600-051X.2012.01873.x
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVES:It is often recommended that manual toothbrushes should be replaced every 3 months. The aim of this study was to compare the effectiveness of new and 3-month-old toothbrushes in the removal of dental plaque. MATERIALS AND METHODS:A single examiner blind, randomized study was performed in which 40 adult pati...
journal_title：Journal of clinical periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1034/j.1600-051x.2002.290709.x
更新日期：2002-07-01 00:00:00
abstract：OBJECTIVE:This paper reports a meta-analysis of studies that have investigated the effect of scaling and root planing on periodontal probing depth and attachment loss. MATERIAL AND METHODS:The criteria used for inclusion of studies were as follows: root planing and scaling alone was one of the primary treatment arms; ...
journal_title：Journal of clinical periodontology
pub_type： 杂志文章,meta分析
doi：10.1034/j.1600-051x.2002.291102.x
更新日期：2002-11-01 00:00:00
