当前位置： SCI文献检索 > Brachytherapy期刊下所有文献 > Palliative treatment by high-dose-rate intraluminal brachytherapy in patients with advanced esophageal cancer.

Palliative treatment by high-dose-rate intraluminal brachytherapy in patients with advanced esophageal cancer.

Abstract：

PURPOSE:The aim of this work was to analyze the results of palliative HDR brachytherapy in patients with advanced esophageal cancer. METHODS AND MATERIALS:Ninety-one patients with unresectable, advanced esophageal cancer were treated palliatively by HDR brachytherapy. All patients received a total dose of 22.5 Gy in three fractions per week. Remissions of dysphagia and other clinical and radiological factors were assessed in the first month posttreatment, and then in the third, sixth, and twelfth months. The survival rate was compared with some chosen clinical factors using a log-rank test and the Kaplan-Meier method. RESULTS:The median survival time among all patients was 8.2 months. The median survival time according to the obtained remission was 14.6, 7.2, and 3.8 months (log-rank p = 00001, F Cox p = 0.00001) for complete remission (CR), partial remission (PR), and lack of remission (NR), respectively. A longer median survival time was observed when tumor size was less then 5 cm (12.1 months), than between 5 and 10 cm (7.8 months), or longer than 10 cm (6.4 months) (log-rank p = 0.002). Longer median survival times were observed in clinical stage II (14.1 months), compared with clinical stage III (7.7 months) and IV (7.2 months) (log-rank p = 0.01). Significant correlations were found between survival and the Karnofsky Performance Status, grade of dysphagia, and age. CONCLUSIONS:HDR brachytherapy for advanced esophageal cancer allowed for improvement of dysphagia in most patients. The complete or partial remission, the older age of patients, and the lower grade of dysphagia observed in first month posttreatment were the most important prognostic factors allowing for prolonged survival (confirmed by a multivariate analysis). In the univariate analysis, important prognostic factors for prolonged survival were: a higher Karnofsky Performance Status, a lower clinical stage and a small tumor size.

journal_name

Brachytherapy

journal_title

Brachytherapy

authors

Skowronek J,Piotrowski T,Zwierzchowski G

doi

10.1016/j.brachy.2004.05.003

keywords:

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

87-94

issue

2

eissn

1538-4721

issn

1873-1449

pii

S1538-4721(04)00062-5

journal_volume

3

pub_type

临床试验,杂志文章

相关文献

Brachytherapy文献大全
  • Californium-252 neutron brachytherapy combined with external beam radiotherapy for esophageal cancer: long-term treatment results.

    abstract：PURPOSE:The aim of this study was to retrospectively observe and analyze the long-term treatment outcomes for a total of 952 esophageal cancer patients who were treated with (252)Cf neutron brachytherapy (NBT) in combination with external beam radiotherapy (EBRT). METHODS AND MATERIALS:From November 2001 to March 2012...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2014.03.004

    authors： Liu H,Wang Q,Wan X,Jia X,Liu B,Wang CK

    更新日期：2014-09-01 00:00:00

  • MammoSite accelerated partial breast irradiation: a single-institution outcomes analysis with 2 years of followup.

    abstract：PURPOSE:To provide longitudinal follow-up and assess the intermediate outcomes in breast cancer patients treated with the MammoSite radiation therapy system. METHODS AND MATERIAL:Ninety-two patients with histologically proven stage 0-II breast cancer were treated with MammoSite accelerated partial breast irradiation a...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2008.07.005

    authors： Haley M,Beriwal S,Heron DE,Kim H,Falk J,Johnson R,Mogus R

    更新日期：2009-01-01 00:00:00

  • Patient-reported health-related quality of life outcomes after HDR brachytherapy between small (

    abstract：PURPOSE:Patients with large prostate glands are underrepresented in clinical trials incorporating brachytherapy due to concerns for excessive toxicity. We sought to compare health-related quality of life (HRQOL) outcomes between small (<60 cc) and large (≥60 cc) prostates treated with high-dose-rate brachytherapy (HDR-...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2018.08.009

    authors： Press RH,Morgan TM,Cutrell PK,Zhang C,Chen Z,Rahnema S,Sanda M,Pattaras J,Patel P,Jani AB,Rossi PJ

    更新日期：2019-01-01 00:00:00

  • Clinical use of magnetic resonance imaging across the prostate brachytherapy workflow.

    abstract：:MRI produces better soft tissue contrast than does ultrasonography or computed tomography for visualizing male pelvic anatomy and prostate cancer. Better visualization of the tumor and organs at risk could allow better conformation of the dose to the target volumes while at the same time minimizing the dose to critica...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2016.11.012

    authors： Blanchard P,Ménard C,Frank SJ

    更新日期：2017-01-01 00:00:00

  • Initiatives for education, training, and dissemination of morbidity assessment and reporting in a multiinstitutional international context: Insights from the EMBRACE studies on cervical cancer.

    abstract：:In 2008, the GEC ESTRO Gyn network launched the first multiinstitutional, observational, and prospective international study on MRI-guided brachytherapy in locally advanced cervical cancer patients (EMBRACE-I). EMBRACE-I was followed by EMBRACE-II from 2016 and ongoing. Among the aims of the EMBRACE studies are to ben...

    journal_title：Brachytherapy

    pub_type： 杂志文章,评审

    doi：10.1016/j.brachy.2020.08.011

    authors： Kirchheiner K,Smet S,Spampinato S,Jensen NBK,Vittrup AS,Fokdal L,Najjari-Jamal D,Westerveld HG,Lindegaard JC,Kirisits C,De Leeuw A,Schmid MP,Tan LT,Nout RA,Jürgenliemk-Schulz IM,Pötter R,Tanderup K,EMBRACE Collaborative

    更新日期：2020-01-01 00:00:00

  • Monte Carlo calculation of the dose perturbations in a dual-source HDR/PDR afterloader treatment unit.

    abstract：PURPOSE:Currently, there are high dose rate afterloaders available that can drive two different radioactive sources simultaneously. The source-source and source-cable attenuations are not taken into account by current planning systems. The purpose of this work is to characterize these effects and their overall impact o...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2016.03.007

    authors： Collins-Fekete CA,Plamondon M,Verhaegen F,Beaulieu L

    更新日期：2016-07-01 00:00:00

  • Dosimetry comparison between TG-43 and Monte Carlo calculations using the Freiburg flap for skin high-dose-rate brachytherapy.

    abstract：PURPOSE:The purpose of this work was to evaluate whether the delivered dose to the skin surface and at the prescription depth when using a Freiburg flap applicator is in agreement with the one predicted by the treatment planning system (TPS) using the TG-43 dose-calculation formalism. METHODS AND MATERIALS:Monte Carlo...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2011.11.005

    authors： Vijande J,Ballester F,Ouhib Z,Granero D,Pujades-Claumarchirant MC,Perez-Calatayud J

    更新日期：2012-11-01 00:00:00

  • Trends in the utilization of adjuvant vaginal brachytherapy in women with early-stage endometrial carcinoma: Results of an updated period analysis of SEER data.

    abstract：PURPOSE:Adjuvant vaginal brachytherapy (VB) is a well-established and effective radiation treatment modality in women with early-stage endometrial carcinoma. We sought to evaluate and update published trends in the utilization of VB vs. other radiation therapy modalities (pelvic external beam radiation therapy (EBRT) o...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2016.06.012

    authors： Modh A,Ghanem AI,Burmeister C,Rasool N,Elshaikh MA

    更新日期：2016-09-01 00:00:00

  • Review of brachytherapy complications - Upper gastrointestinal tract.

    abstract：:While brachytherapy applications are not widely used for cancer diagnoses in the upper GI tract (including the esophagus, liver, stomach, and pancreas), they have a clear role in palliation and symptom management and occasionally definitive locoregional treatment. With the increasing use of image-guided techniques, th...

    journal_title：Brachytherapy

    pub_type： 杂志文章,评审

    doi：10.1016/j.brachy.2020.11.010

    authors： Folkert MR,Gottumukkala S,Nguyen NT,Taggar A,Sur RK

    更新日期：2020-12-22 00:00:00

  • Salvage low-dose-rate brachytherapy for local recurrences after prostatectomy and adjuvant or salvage external beam irradiation: Feasibility study on five patients and literature review.

    abstract：PURPOSE:To assess the feasibility and tumor outcome of re-irradiation with low-dose-rate brachytherapy for macroscopic local recurrences after radical prostatectomy (RP) followed by adjuvant or salvage external beam radiation therapy (EBRT). METHODS AND MATERIALS:Between 2011 and 2018, five men with histologically pro...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2020.07.001

    authors： Le Roy C,Gassa F,Rouvière O,Desmettre O,Bringeon G,Charret J,Serre AA,Pommier P

    更新日期：2021-01-01 00:00:00

  • Morbidity and prostate-specific antigen control of external beam radiation therapy plus low-dose-rate brachytherapy boost for low, intermediate, and high-risk prostate cancer.

    abstract：PURPOSE:Dose escalation has been shown beneficial in prostate cancer. Brachytherapy (BT) provides an opportunity for dose escalation beyond what can be safely delivered using only teletherapy methods. The purpose of this study was to determine cancer control and morbidity of external beam radiation therapy (EBRT) plus ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2009.01.002

    authors： Koontz BF,Chino J,Lee WR,Hahn CA,Buckley N,Huang S,Kim J,Reagan R,Joyner R,Anscher MS

    更新日期：2009-04-01 00:00:00

  • A prospective dose escalation trial of high-dose-rate brachytherapy boost for prostate cancer: Evidence of hypofractionation efficacy?

    abstract：PURPOSE:The study aimed to evaluate mature outcomes of a Phase I/II high-dose-rate brachytherapy (HDRB) boost protocol. METHODS AND MATERIALS:We analyzed data from 88 patients with T1a-T3a, N0, M0 prostate adenocarcinoma treated on a prospective Phase I/II HDRB boost protocol of 16 (n = 47) or 20 Gy (n = 41) in four f...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2006.08.007

    authors： Tang JI,Williams SG,Tai KH,Dean J,Duchesne GM

    更新日期：2006-10-01 00:00:00

  • Impact of experience and technical changes on acute urinary and rectal morbidity in low-dose prostate brachytherapy using loose seeds real-time implantation.

    abstract：PURPOSE:To assess the impact of experience and technical changes on morbidity during the first year after permanent prostate brachytherapy. METHODS AND MATERIALS:From July 2003 to May 2010, 150 patients with prostate cancer underwent low-dose iodine-125 prostate brachytherapy as a monotherapy by the same medical team ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2013.04.002

    authors： Le Fur E,Malhaire JP,Nowak E,Rousseau B,Erauso A,Pene-Baverez D,Papin G,Delage F,Perrouin-Verbe MA,Fournier G,Pradier O,Valeri A

    更新日期：2013-11-01 00:00:00

  • The effect of loose versus stranded seeds on biochemical no evidence of disease in patients with carcinoma of the prostate treated with iodine-125 brachytherapy.

    abstract：PURPOSE:The British Columbia Cancer Agency has been performing iodine-125 prostate brachytherapy since 1998, initially using loose seeds and phasing into the exclusive use of RAPIDStrand (RS) (Oncura Inc., Plymouth Meeting, PA) by November 2000. The aim of this study was to investigate rates of biochemical no evidence ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2011.01.011

    authors： Herbert C,Morris WJ,Hamm J,Lapointe V,McKenzie M,Pickles T,Spadinger I,Keyes M

    更新日期：2011-11-01 00:00:00

  • Salvage wide resection with intraoperative electron beam therapy or HDR brachytherapy in the management of isolated local recurrences of soft tissue sarcomas of the extremities and the superficial trunk.

    abstract：PURPOSE:To assess the toxicity and efficacy of salvage wide resection (SWR) with intraoperative electron beam radiation therapy (IOERT) or perioperative high-dose-rate brachytherapy (PHDRB) in previously unirradiated patients (PUP) vs. previously irradiated patients (PIP) with isolated local recurrence of soft tissue s...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2014.09.003

    authors： Cambeiro M,Aristu JJ,Moreno Jimenez M,Arbea L,Ramos L,San Julian M,Azinovic I,Calvo FA,Martínez-Monge R

    更新日期：2015-01-01 00:00:00

  • Dose homogeneity analysis of adjuvant radiation treatment in surgically resected brain metastases: Comparison of IORT, SRS, and IMRT indices.

    abstract：PURPOSE:Although surgery remains a treatment option for symptomatic brain metastases, the need for adjuvant radiation after surgery is widely accepted as standard. Despite a multitude of randomized trials aimed at identifying the ideal radiation treatment plan for surgically resected metastases, the development of new ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2020.11.004

    authors： Dahshan BA,Weir JS,Bice RP,Renz P,Cifarelli DT,Poplawski L,Hack J,Vargo JA,Cifarelli CP

    更新日期：2021-01-13 00:00:00

  • #ThisIsBrachytherapy: Increasing awareness of brachytherapy.

    abstract：PURPOSE:The use of brachytherapy continues to be a vital application of radiation oncology for various cancers. Despite this, there has been a decrease in the utilization of brachytherapy in many cancers. Social media in medicine facilitates engagement and advocacy. We launched a social media campaign to bring awarenes...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2020.07.003

    authors： Kahn JM,Campbell SR,Albert AA,Knoll MA,Shah C

    更新日期：2021-01-01 00:00:00

  • Bone HDR brachytherapy in a patient with recurrent Ewing's sarcoma of the acetabulum: alternative to aggressive surgery.

    abstract：:A 17-year-old girl diagnosed with a previously irradiated, locally recurrent Ewing's sarcoma involving the puboischiatic rami and the adjacent acetabulum was referred to our institution for consideration of salvage hindquarter resection. A conservative resection with implantation of the acetabular remnant for high-dos...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/S1538-4721(03)00098-9

    authors： Martínez-Monge R,Pérez-Ochoa A,San Julián M,Aquerreta D,Sierrasesúmaga L

    更新日期：2003-01-01 00:00:00

  • Initial analysis of Pro-Qura: a multi-institutional database of prostate brachytherapy dosimetry.

    abstract：PURPOSE:The study aimed to analyze the Pro-Qura database in terms of patient implant sequence number for each institution to determine evidence for a dosimetric learning curve. METHODS AND MATERIALS:In the Pro-Qura database, 2833 of a total of 4614 postplans from 57 brachytherapists were analyzed for evidence of a dos...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2006.10.002

    authors： Merrick GS,Grimm PD,Sylvester J,Blasko JC,Butler WM,Allen ZA,Chaudhry UU,Mazza A,Sitter M

    更新日期：2007-01-01 00:00:00

  • Improved survival for patients with prostate cancer receiving high-dose-rate brachytherapy boost to EBRT compared with EBRT alone.

    abstract：PURPOSE:High-dose-rate (HDR) brachytherapy boost is a treatment of intermediate- to high-risk prostate cancer, but long-term clinical outcome data are sparse. We report long-term survival and toxicity data in a cohort of patients treated in a single institution. METHODS:Between 1998 and 2004, 654 patients with localiz...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2019.01.013

    authors： Kent AR,Matheson B,Millar JL

    更新日期：2019-01-01 00:00:00

  • A dose verification tool for high-dose-rate interstitial brachytherapy treatment planning in accelerated partial breast irradiation.

    abstract：PURPOSE:To develop a dose verification tool for high-dose-rate interstitial brachytherapy treatment planning in accelerated partial breast irradiation. METHODS AND MATERIALS:We have developed a software tool for interstitial brachytherapy treatment planning assessment. The software contains a database of seven (192)Ir...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2012.03.008

    authors： Marqa MF,Caudrelier JM,Betrouni N

    更新日期：2012-09-01 00:00:00

  • Intraoperative adaptive brachytherapy of iodine-125 prostate implants guided by C-arm cone-beam computed tomography-based dosimetry.

    abstract：PURPOSE:(1) To demonstrate the feasibility of C-arm cone-beam computed tomography (CBCT)-based postplanning and subsequent adaptation of underdosed critical areas by adding remedial seeds during the transrectal ultrasound (TRUS)-guided implantation of (125)I seeds and (2) to assess the duration of this procedure. METH...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2007.08.005

    authors： Westendorp H,Hoekstra CJ,van't Riet A,Minken AW,Immerzeel JJ

    更新日期：2007-10-01 00:00:00

  • Exploring the potential of mixed-source brachytherapy for the treatment of cervical cancer using high-dose rate 192Ir and/or 50 kV electronic sources.

    abstract：PURPOSE:In this study, computer modeling was used to compare the relative doses with the bladder, rectum, and bowel when two different brachytherapy modalities were used to treat cervical cancer with a tandem and ovoid applicator. A standard high-dose rate (HDR) (192)Ir treatment plan was compared with a "mixed-source"...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2010.08.009

    authors： Cohen DM,Hiatt JR,O'Connor B,Curran B,Sternick ES,Wazer DE

    更新日期：2011-03-01 00:00:00

  • Improving patient-specific dosimetry for intravascular brachytherapy.

    abstract：PURPOSE:Accurate patient-specific dosimetry in intravascular brachytherapy (IVBT) is generally difficult due to the extremely high-dose gradient, complexity of treatment device, and patient-specific geometry (e.g., calcification, stent, curvature, movement of target). The purpose of this study is to analyze quantitativ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2005.07.004

    authors： Li XA,O'Neill M,Suntharalingam M

    更新日期：2005-01-01 00:00:00

  • Income generated by women treated with magnetic resonance imaging-based brachytherapy: A simulation study evaluating the macroeconomic benefits of implementing a high-end technology in a public sector healthcare setting.

    abstract：PURPOSE:To estimate the difference in income generated if all women presenting in our institute over a 5-year period were treated with MRI-based image-guided brachytherapy (MR-IGBT) instead of conventional radiograph-based brachytherapy (CR-BT). METHODS AND MATERIALS:Outcome data from 463 patients (94 treated with MR-...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2017.05.003

    authors： Chakraborty S,Mahantshetty U,Chopra S,Lewis S,Hande V,Gudi S,Krishnatry R,Engineer R,Shrivastava SK

    更新日期：2017-01-01 00:00:00

  • Single-energy metal artifact reduction in postimplant computed tomography for I-125 prostate brachytherapy: Impact on seed identification.

    abstract：PURPOSE:To evaluate the effectiveness of the single-energy metal artifact reduction (SEMAR) technique for improving the accuracy of I-125 seed identification in postimplant computed tomography (CT) after prostate brachytherapy. METHODS AND MATERIALS:Postimplant CT images of 40 patients treated with I-125 prostate brac...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2016.07.006

    authors： Shiraishi Y,Yamada Y,Tanaka T,Eriguchi T,Nishimura S,Yoshida K,Hanada T,Ohashi T,Shigematsu N,Jinzaki M

    更新日期：2016-01-01 00:00:00

  • Intravascular brachytherapy using 90Sr for saphenous vein grafts having diameters ranging from 2.0-5.0 mm.

    abstract：PURPOSE:Symptomatic coronary artery disease is routinely treated with angioplasty and stenting. Unfortunately, treatment failure in the form of in-stent restenosis (ISR) occurs relatively frequently. Intravascular brachytherapy (IVBT) is a safe and effective method proven to markedly reduce the rate of ISR in native co...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2004.05.004

    authors： Mignano JE,Rivard MJ

    更新日期：2004-01-01 00:00:00

  • Comparison of outcome endpoints in intermediate- and high-risk prostate cancer after combined-modality radiotherapy.

    abstract：PURPOSE:To compare a standard radio-oncological and a surgical biochemical failure definition after combined-modality radiation therapy (CRT) in men with intermediate- and high-risk prostate cancer. METHODS:425 men were treated with external beam radiotherapy (59.4 Gy, 33 fractions) and 125J seed-brachytherapy (S-BT, ...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2019.09.001

    authors： Boehle A,Katic K,König IR,Robrahn-Nitschke I,Brandenburg B

    更新日期：2020-01-01 00:00:00

  • Moving toward uniform and evidence-based practice of radiotherapy for management of cervical cancer in Ontario, Canada.

    abstract：PURPOSE:To recognize the practice of radiotherapy for management of cervical cancer in Ontario, Canada, and to use the results of the survey to harmonize and standardize practice across the province. METHODS AND MATERIALS:An electronic survey (SurveyMonkey) was sent to all 14 provincial cancer centers by Cancer Care O...

    journal_title：Brachytherapy

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.brachy.2018.03.003

    authors： Shahid N,Craig T,Westerland M,Ashworth A,Ang M,D'Souza D,Sankreacha R,Fyles A,Milosevic M,Kong I,Cancer Care Ontario Radiation Treatment Gynecologic Oncology Community of Practice.

    更新日期：2018-01-01 00:00:00

  • Changes in brachytherapy-based APBI patient selection immediately before and after publication of the ASTRO consensus statement.

    abstract：PURPOSE:In July 2009, American Society of Radiation Oncology (ASTRO) released a consensus statement (CS) to guide patient selection for accelerated partial breast irradiation (APBI). The goal of this study was to examine how practice patterns changed following the guideline's release. METHODS:The Surveillance, Epidemi...

    journal_title：Brachytherapy

    pub_type： 杂志文章

    doi：10.1016/j.brachy.2015.03.003

    authors： Husain ZA,Lloyd S,Shah C,Wilson LD,Koshy M,Mahmood U

    更新日期：2015-07-01 00:00:00