Abstract:
BACKGROUND:Electrical stimulation of the visual cortex with surface electrodes is able to elicit basic visual perceptions in blind patients. The development of a visual prosthesis for the blind will require an in-vivo model for the optimization of cortical neurostimulation with multielectrode arrays. METHODS:In anaesthetized cats a bilateral craniotomy was performed and the dura was removed to expose the cerebral cortex. A prototype stimulating electrode array was placed on a gyrus in one hemisphere, and the transcallosal evoked response (TER) to cortical stimulation by this electrode array was recorded at a homologous region in the contralateral hemisphere. RESULTS:The stimulating electrode array elicited TER of short latency (6.9 ms) in the contralateral hemisphere. Bipolar stimulation of adjacent electrodes on the array evoked similar TER regardless of the polarity of stimulation. Electrodes spread apart on the array caused higher amplitude TER than electrodes placed close together. Multielectrode stimulation evoked lower amplitude TER than bipolar stimulation. CONCLUSIONS:This transcallosal model of cortical neurostimulation is a useful method to evaluate electrode arrays and stimulation techniques in the development of a visual prosthesis.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Chowdhury V,Morley JW,Coroneo MTdoi
10.1111/j.1445-1433.2004.02983.xkeywords:
subject
Has Abstractpub_date
2004-05-01 00:00:00pages
372-8issue
5eissn
1445-1433issn
1445-2197pii
ANS2983journal_volume
74pub_type
杂志文章abstract:BACKGROUND:Compared with other doctors, surgeons are at an increased risk of medicolegal events, including patient complaints and negligence claims. This retrospective study aimed to describe the frequency and nature of complaints involving surgeons compared with physicians. METHODS:We assembled a national data set of...
journal_title:ANZ journal of surgery
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更新日期:2018-04-01 00:00:00
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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journal_title:ANZ journal of surgery
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更新日期:2017-07-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:2015-03-01 00:00:00
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更新日期:2007-06-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2013-12-01 00:00:00
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更新日期:2018-07-01 00:00:00
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更新日期:2005-04-01 00:00:00
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journal_title:ANZ journal of surgery
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更新日期:2015-04-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2014-07-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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journal_title:ANZ journal of surgery
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更新日期:2013-01-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
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更新日期:2020-05-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2017-10-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章,随机对照试验
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更新日期:2005-08-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03975.x
更新日期:2007-01-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1440-1622.2001.02046.x
更新日期:2001-02-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2011.05955.x
更新日期:2012-01-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
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更新日期:2009-04-01 00:00:00
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journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13979
更新日期:2018-05-01 00:00:00