Nocardia beijingensis, is a pathogenic bacterium to humans: the first infectious cases in Thailand and Japan.

Abstract:

:Nocardia beijingensis, a recently established new species, is an isolate from soil in China. During our taxonomic studies on 450 nocardial clinical isolates in Thailand and Japan, 17 strains from Thailand and 1 strain from Japan were found to have a similar physiological characteristic to those of N. beijingensis, such as a drug susceptibility pattern to three antimicrobial agents. Our phylogenetic studies on these 18 strains by 16S rRNA gene sequence analysis confirmed that these strains belong to N. beijingensis species. Phylogenetically, these newly isolated N. beijingensis strains were found to be classified into two distinct clades: one is a Japanese clade and other is a Chinese clade, including a reference strain and 17 Thai strains. This is the first report of human infection due to N. beijingensis strains, and we propose that the bacterium be categorized as an opportunistic infectious group regardless of its original isolation from soil.

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Kageyama A,Poonwan N,Yazawa K,Mikami Y,Nishimura K

doi

10.1023/b:myco.0000020588.60081.37

keywords:

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

155-61

issue

2

eissn

0301-486X

issn

1573-0832

journal_volume

157

pub_type

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