Abstract:
PURPOSE OF REVIEW:To review how to critically appraise a research article pertaining to changes in health-related quality of life (HRQoL) related to interventions for age-related macular degeneration (AMD). RECENT FINDINGS:We searched PubMed using a strategy that combined the text-words, "macular degeneration" and "quality of life" (n = 73; January 17, 2004), while limiting the search to "clinical trials" (n = 6; of which 3 were published within the past year). A randomized clinical trial evaluating the efficacy of self-management as an intervention for AMD has been selected to introduce the reader to the concept of how to critically review a research paper pertaining to HRQoL in AMD. Other pertinent articles used in this review include recent results published from the Age-Related Eye Disease Study and the Submacular Surgery Trial. SUMMARY:The NEI-VFQ is a reliable, valid, and responsive tool when applied to patients with AMD. Self-management of patients with AMD has been demonstrated to improve their HRQoL by way of an internally valid randomized clinical trial. In this issue of Current Opinion in Ophthalmology, we confront the issue of how to assess the validity and importance of a research paper pertaining to the issue of quality of life. To introduce this topic, we will present a real world clinical example to better understand how quality of life may aid in medical decision making.
journal_name
Curr Opin Ophthalmoljournal_title
Current opinion in ophthalmologyauthors
Sharma S,Oliver-Fernandez Adoi
10.1097/01.icu.0000124082.88389.cfkeywords:
subject
Has Abstractpub_date
2004-06-01 00:00:00pages
227-31issue
3eissn
1040-8738issn
1531-7021pii
00055735-200406000-00012journal_volume
15pub_type
杂志文章,评审abstract::Radiotherapy has become increasingly important for the treatment of complicated choroidal hemangiomas. In recent years, a broad spectrum of different radiotherapeutic options that either replace or complement the conventional therapeutic approach by photocoagulation has been recommended. This article reviews the vario...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199806000-00009
更新日期:1998-06-01 00:00:00
abstract::The optic nerve head and the retinal nerve fiber layer (RNFL) are the sites of clinically detectable glaucomatous tissue damage. Photographic techniques are used to document the optic disk and the RNFL to monitor patients with suspected primary open-angle glaucoma or to follow-up patients already suffering from this d...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199604000-00017
更新日期:1996-04-01 00:00:00
abstract::Human amniotic membrane (AM) is composed of three layers: a single epithelial layer, a thick basement membrane, and an avascular stroma. Amniotic membrane has anti-adhesive properties and is felt to promote epithelialization and decrease inflammation, neovascularization, and fibrosis. Amniotic membrane transplantation...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200108000-00006
更新日期:2001-08-01 00:00:00
abstract::Clonidine hydrochloride, apraclonidine hydrochloride, and brimonidine tartrate constitute the three topical alpha agonists that are used in the treatment of elevated intraocular pressure. All the alpha agonists have prejunctional (alpha 2) as well as postjunctional (alpha 1) effects. Within the past year, questions ha...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199804000-00006
更新日期:1998-04-01 00:00:00
abstract:PURPOSE OF REVIEW:To summarize the ocular and systemic associations of floppy eyelid syndrome (FES) as well as provide an up-to-date review on the pathogenesis and treatment strategies. RECENT FINDINGS:Virtually all patients with FES have obstructive sleep apnea (OSA). However, a significantly lower proportion of pati...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000617
更新日期:2019-11-01 00:00:00
abstract::There have been many recent advances in the diagnosis and management of children with retinoblastoma. Regarding diagnosis, the judicial use of ancillary studies, particularly B-scan ultrasonography, has been instrumental in supplementing the diagnosis when opaque media preclude a clear view of the underlying neoplasm...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199406000-00014
更新日期:1994-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The successful treatment of canalicular obstructions continues to represent a therapeutic challenge. Conjuctivodacryocystorhinostomy with a Lester Jones bypass tube is the standard treatment in these situations. Although a high rate of anatomic success can be achieved with this procedure, a relatively...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32832ec3e0
更新日期:2009-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Diabetic retinopathy is common and increasing in prevalence. Pharmacologic management of diabetic macular edema (DME) has improved tremendously over the last decade with the use of two families of intravitreally administered medications: antivascular endothelial growth factor-specific agents and corti...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000364
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Radiation retinopathy remains a devastating cause of visual morbidity in patients undergoing radiation for globe, orbit, and head and neck malignancies. This review discusses the recent efforts of several authors to treat radiation retinopathy once it has developed and efforts to prevent its developme...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000141
更新日期:2015-05-01 00:00:00
abstract:PURPOSE OF REVIEW:To present an overview on the clinical manifestations and an update on the current management of neuromyelitis optica (NMO). RECENT FINDINGS:NMO is associated with a significant risk of neurological, ocular and systemic morbidity. Many cases of NMO assume a relapsing course, which can lead clinicians...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3283313d1d
更新日期:2009-11-01 00:00:00
abstract::A wealth of antiallergic drugs is available for ocular allergy, and many new drugs will soon be approved. Pharmaceutical companies frequently seek approval of anti-inflammatory drugs for allergic indications, because it is relatively easy to perform clinical trials for ocular allergy. Extremely safe drugs for mild to ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199808000-00010
更新日期:1998-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Posterior vitreous detachment is the principal predisposing event for the development of retinal breaks and rhegmatogenous retinal detachments. Patients with unilateral posterior vitreous detachment are potentially at risk of developing the complications associated with posterior vitreous detachment i...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3281299022
更新日期:2007-05-01 00:00:00
abstract::Dacryocystorhinostomy remains the mainstay of treatment of acquired primary and secondary obstructions of the lacrimal drainage system. The advent of the endoscope has prompted renewed interest in the intranasal or endonasal approach to fistulae formation. As results of the intranasal approach are reported, they are c...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199610000-00010
更新日期:1996-10-01 00:00:00
abstract:PURPOSE OF REVIEW:A variety of options exist for perioperative, intraoperative, and postoperative medications in cataract surgery. This article reviews some of the more timely literature on "controversial" subjects in this area. RECENT FINDINGS:Recent literature may support the rationale for intracameral vancomycin at...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200402000-00010
更新日期:2004-02-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe the emerging applications of deep learning in ophthalmology. RECENT FINDINGS:Recent studies have shown that various deep learning models are capable of detecting and diagnosing various diseases afflicting the posterior segment of the eye with high accuracy. Most of the initial studies hav...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000470
更新日期:2018-05-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe trends in corneal transplantation surgery, including indications for surgery, evolution of lamellar keratoplasty, current surgical techniques, and future directions. RECENT FINDINGS:Over the past decade, anterior and posterior lamellar keratoplasty have begun to supplant penetrating kerat...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000080
更新日期:2014-07-01 00:00:00
abstract::Ophthalmologic nystagmus can be congenital and manifest/latent both of whose waveforms, compensatory mechanisms, and treatment are different. Physiologically, latent nystagmus may be reversed at will, whereas nystagmus and head nodding may be simultaneously triggered at will. Occasional oscillopsia is more frequent th...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1994-10-01 00:00:00
abstract::Antiphospholipid syndrome includes elevation of either the lupus anticoagulant titer or the anticardiolipin antibody titer on two occasions, separated by 6 weeks in a patient with an episode of thrombosis. The eye is involved frequently in patients with antiphospholipid syndrome. Patients with retinal vascular disease...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200006000-00011
更新日期:2000-06-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to update the clinician on the recent work in the field of pediatric glaucoma. RECENT FINDINGS:Using the iCare tonometer to measure intraocular pressure (IOP) in children is highly successful. New data from the Infant Aphakia Treatment Study show that after 5 years of fo...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000349
更新日期:2017-03-01 00:00:00
abstract::Horner syndrome refers to the constellation of signs resulting from the interruption of sympathetic innervation to the eye and ocular adnexae. Classically, the clinical findings include a triad of ipsilateral blepharoptosis, pupillary miosis, and facial anhidrosis. The history, additional clinical examination features...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-200312000-00007
更新日期:2003-12-01 00:00:00
abstract::Performing flawless cosmetic blepharoplasty surgery requires attention to many details. A proper medical work-up with establishment of patient rapport and preoperative photographic documentation should begin the evaluation. The surgical correction of concomittant brow position abnormalities should be considered. Res...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199110000-00013
更新日期:1991-10-01 00:00:00
abstract:PURPOSE OF REVIEW:Sarcoidosis is a multisystemic inflammatory disease that commonly affects the eye and less often the neuro-ophthalmic pathways. The manifestations can be quite variable but can have characteristic signs and clinical features. This review provides a comprehensive overview of the various ocular and neur...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000415
更新日期:2017-11-01 00:00:00
abstract:PURPOSE OF REVIEW:A significant recent advancement in the treatment of neovascularization of the anterior segment of the eye is the development of antivascular endothelial growth factor (anti-VEGF) therapeutic agents.We present a review of the current knowledge on anti-VEGF therapy with bevacizumab for anterior segment...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e3283548459
更新日期:2012-07-01 00:00:00
abstract::The detection of true visual field deterioration in glaucoma is of fundamental importance but is limited by inherent variability of the measurements. New techniques have been developed that use powerful statistical regression analysis methods to objectively quantify progression of visual field defects. These have be...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章
doi:10.1097/00055735-199404000-00016
更新日期:1994-04-01 00:00:00
abstract::The current literature and meeting abstracts regarding combined cataract and glaucoma surgery are reviewed. Potential acuity measurements are compared. Intraoperative manipulation of the pupil, wound size, antimetabolites, and types of filtration surgery are also discussed. Postoperative intraocular pressure rise, f...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1993-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Pseudoexfoliation syndrome (XFS) is a late-onset and complex disorder that is strongly associated with the development of glaucoma. The purpose of this review is to discuss the inheritance patterns and recent genetic advances in the study of this disorder. RECENT FINDINGS:XFS has a strong familial as...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e328320d86a
更新日期:2009-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The introduction of hydrogel socket and orbital expanders has modified the approach towards the rehabilitation of congenital anophthalmia. This study highlights the most recent advances for the treatment of congenital anophthalmia based on personal experience and the review of recent literature. RECE...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e328349948a
更新日期:2011-09-01 00:00:00
abstract::The surgical management of Graves ophthalmopathy includes treatment of globe malposition (exophthalmos), strabismus, and eyelid abnormalities. The various techniques used continue to be refined and are detailed in this review. ...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/00055735-199910000-00012
更新日期:1999-10-01 00:00:00
abstract:PURPOSE OF REVIEW:To review recent data on the effects of smoking on ocular health. RECENT FINDINGS:Smoking has been associated with a myriad of negative ocular health effects including age-related macular degeneration (ARMD) and cataract. Most recently, several papers have demonstrated a connection between smoking an...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0b013e32834bbe7a
更新日期:2011-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the efficacy of intrastromal corneal ring segments (ICRS) for keratoconus and with other interventions such as contacts lens, keratoplasty, and corneal collagen cross-linking. RECENT FINDINGS:Changes in ICRS thickness and size, combination of procedures, and the adaptation of a more sophist...
journal_title:Current opinion in ophthalmology
pub_type: 杂志文章,评审
doi:10.1097/ICU.0000000000000582
更新日期:2019-07-01 00:00:00