Pigmentary characteristics, sun sensitivity and non-Hodgkin lymphoma.

Abstract:

:We report on pigmentary characteristics, sun sensitivity and some other possible risk factors for non-Hodgkin lymphoma (NHL) in people 20-74 years of age. A statewide case-control study was conducted in New South Wales, Australia, with population-based sampling of cases (n = 704) and controls (n = 694). Risk of NHL was increased in subjects with hazel eyes (OR = 1.48; 95% CI = 1.07-2.04), very fair skin (OR = 1.44; 95% CI = 1.01-2.07) and poor ability to tan (OR = 1.70; 95% CI = 1.06-2.71). Risk with mild facial freckling as a child (OR = 0.77; 95% CI = 0.59-0.99) was reduced relative to that with no or moderate to severe freckling. Smokers were not at increased risk of NHL. A past history of treatment for skin cancer was associated with a slight nonsignificant increase in risk. Previous radiotherapy and chemotherapy were associated with 1.5- to 2-fold increases in risk but with wide confidence intervals. These results provide weak support for the possibility that sun sensitivity or perhaps sun exposure increases risk of NHL.

journal_name

Int J Cancer

authors

Hughes AM,Armstrong BK,Vajdic CM,Turner J,Grulich A,Fritschi L,Milliken S,Kaldor J,Benke G,Kricker A

doi

10.1002/ijc.20128

keywords:

subject

Has Abstract

pub_date

2004-06-20 00:00:00

pages

429-34

issue

3

eissn

0020-7136

issn

1097-0215

journal_volume

110

pub_type

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