RNA conformational classes.

Abstract:

:RNA exhibits a large diversity of conformations. Three thousand nucleotides of 23S and 5S ribosomal RNA from a structure of the large ribosomal subunit were analyzed in order to classify their conformations. Fourier averaging of the six 3D distributions of torsion angles and analyses of the resulting pseudo electron maps, followed by clustering of the preferred combinations of torsion angles were performed on this dataset. Eighteen non-A-type conformations and 14 A-RNA related conformations were discovered and their torsion angles were determined; their Cartesian coordinates are available.

journal_name

Nucleic Acids Res

journal_title

Nucleic acids research

authors

Schneider B,Morávek Z,Berman HM

doi

10.1093/nar/gkh333

keywords:

subject

Has Abstract

pub_date

2004-03-11 00:00:00

pages

1666-77

issue

5

eissn

0305-1048

issn

1362-4962

pii

32/5/1666

journal_volume

32

pub_type

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