Dietary boron intake and prostate cancer risk.

abstract：:Clear cell renal cell carcinoma (ccRCC) is the main subtype of malignant kidney cancer. Long non‑coding RNA (lncRNA) serves a key role in predicting survival in patients with cancer. The present study aimed to develop an lncRNA‑related signature of prognostic values for patients with ccRCC. RNA sequencing data of 454 ...

journal_title：Oncology reports

authors： Liu T,Sui J,Zhang Y,Zhang XM,Wu WJ,Yang S,Xu SY,Hong WW,Peng H,Yin LH,Pu YP,Liang GY

更新日期：2018-09-01 00:00:00

abstract：:LKB1 encodes a serine/threonine kinase generally inactivated in human lung cancers, which mediates cancer cell proliferation, migration and differentiation, but its biological function has not been completely elucidated. In this study, we demonstrated that LKB1 was associated with a substantial reduction of c-myc expr...

journal_title：Oncology reports

authors： Liang X,Nan KJ,Li ZL,Xu QZ

更新日期：2009-04-01 00:00:00

abstract：:The expression levels of tissue factor (TF), the clotting initiator protein, have been correlated with angiogenesis and the histological grade of malignancy in glioma patients. The pro-tumor function of TF is linked to a family of G protein-coupled receptors known as protease-activated receptors (PARs), which may be a...

journal_title：Oncology reports

authors： Carneiro-Lobo TC,Lima MT,Mariano-Oliveira A,Dutra-Oliveira A,Oba-Shinjo SM,Marie SK,Sogayar MC,Monteiro RQ

更新日期：2014-02-01 00:00:00

abstract：:We investigated the prevalence of human papillomavirus (HPV) in a clinical series of 72 patients with head and neck squamous cell carcinoma (HNSCC) using a retrospective and prospective study design. The majority of patients were smokers and/or drinkers and were treated with concomitant chemoradiotherapy (CCR). Furthe...

journal_title：Oncology reports

authors： Duray A,Descamps G,Decaestecker C,Sirtaine N,Gilles A,Khalifé M,Chantrain G,Depuydt CE,Delvenne P,Saussez S

更新日期：2013-07-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are involved in tumor invasion, but their prognostic significance is still under discussion. We set out to analyze the epithelial and stromal expression of MMP-2, MMP-7, MMP-9, MT1-MMP, TIMP-1 and TIMP-2 in advanced epithelial ovarian cancers and to ...

journal_title：Oncology reports

authors： Brun JL,Cortez A,Lesieur B,Uzan S,Rouzier R,Daraï E

更新日期：2012-04-01 00:00:00

abstract：:Oral cancer is one of the leading types of cancer and remains the most common cause of cancer‑related mortality in Asia. The pathogenesis of oral cancer is complicated and, due to lack of accurate diagnostic methods and efficient treatment strategies, oral cancer is responsible for a large number of deaths. Therefore,...

journal_title：Oncology reports

authors： Wang J,Lv N,Lu X,Yuan R,Chen Z,Yu J

更新日期：2021-01-01 00:00:00

abstract：:In this study, we investigated the sequence variation and different transcriptional activities of the upstream regulatory region (URR) in HPV 16 E7 variants in cervical cancer tissue from Korean women. Using PCR-directed sequencing, the presence of sequence variations in URRs were analyzed and the sites of sequence va...

journal_title：Oncology reports

authors： Kim YB,Song YS,Jeon YT,Park JS,Um SJ,Kim JW,Park NH,Kang SB,Lee HP

更新日期：2005-08-01 00:00:00

abstract：:Telomerase activation is prevalent in most epithelial tumors, and may be a critical step in cellular immortalization and carcinogenesis. However, telomerase activity in tumors of mesenchymal origin is not well understood. In the present study, we examined telomerase activity in clinical samples from osteosarcoma and s...

journal_title：Oncology reports

authors： Terasaki T,Kyo S,Takakura M,Maida Y,Tsuchiya H,Tomita K,Inoue M

更新日期：2004-06-01 00:00:00

abstract：:Single nucleotide polymorphisms (SNPs) in cancer-related genes can act as low risk genetic factors for the development of this disease. SNPs have also been shown to influence the efficacy and toxicity of various cytotoxic agents used in the treatment of cancer. Progress in these important areas of cancer research reli...

journal_title：Oncology reports

authors： Grieu F,Joseph D,Norman P,Iacopetta B

更新日期：2004-02-01 00:00:00

abstract：:Significance of expression of cytokine induced nitric oxide synthase (iNOS) in colorectal carcinoma remains controversial. The aim of the current study was to elucidate the significance of immunohistochemical expression of iNOS in colorectal carcinoma. The subjects were the 54 patients with colorectal carcinoma, inclu...

journal_title：Oncology reports

authors： Nozoe T,Yasuda M,Honda M,Inutsuka S,Korenaga D

更新日期：2002-05-01 00:00:00

abstract：:T cell-mediated cell immunity is the main anti-tumor immunity in which the effector T cells need specific antigen and costimulatory signals. One of the vaccines applied in tumor immunotherapy is the gene-modified tumor cell vaccine. One potential method to increase cell epitope density is to link the antigen with the ...

journal_title：Oncology reports

authors： Fang L,Wang K,Liu X,Zhang L,Zhang X,Qian L,Lu J,Qian G,Ge S

更新日期：2008-06-01 00:00:00

abstract：:MicroRNAs (miRNAs/miRs) in exosomes play crucial roles in the onset, progression and metastasis of cancer by regulating the stability of target mRNAs or by inhibiting translation. In the present study, differentially expressed miRNAs were identified in exosomes of 27 breast cancer patients and 3 healthy controls using...

journal_title：Oncology reports

authors： Wu H,Wang Q,Zhong H,Li L,Zhang Q,Huang Q,Yu Z

更新日期：2020-01-01 00:00:00

abstract：:Tumor invasion and migration are major causes of mortality in patients with cervical carcinoma. Tumors under hypoxic conditions are more invasive and have a higher metastasic activity. Lysyl oxidase (LOX) is a hypoxia-responsive gene. LOX has been shown to be essential for hypoxia-induced metastasis in breast cancer. ...

journal_title：Oncology reports

authors： Yang X,Li S,Li W,Chen J,Xiao X,Wang Y,Yan G,Chen L

更新日期：2013-02-01 00:00:00

abstract：:Cigarette smoke has been implicated as a major risk factor for esophageal squamous cell carcinoma (ESCC). Several lines of evidence have suggested that the promoting effect of cigarette smoking extract (CSE) on ESCC is mediated by upregulation of cyclooxygenase-2 (COX-2) expression. Yet, the underlying molecular and c...

journal_title：Oncology reports

authors： Gong J,Chu Y,Xu M,Huo J,Lv L

更新日期：2016-01-01 00:00:00

abstract：:The transmembrane (TM) receptor encoded by the HER-2 proto-oncogene (HER-2) is amplified in several types of human carcinomas and premalignant states and provides an important target for cancer therapy. While overexpression of HER-2 should lead to increased CTL epitope formation due to the attendant increase in higher...

journal_title：Oncology reports

authors： Castilleja A,Ward NE,Epstein RB,Kudelka AP,Gershenson DM,Efferson CL,O'Brian CA,Ioannides CG

更新日期：2002-09-01 00:00:00

abstract：:v-ets erythroblastosis virus E26 oncogene homolog 1 (ETS-1) plays crucial roles in a spectrum of malignancies. ETS-1 has gained attention in cancer research for its importance in cell migration, invasion and proliferation. In the present study, we focused on the effect of ETS-1 on epithelial-mesenchymal transition (EM...

journal_title：Oncology reports

authors： Li C,Wang Z,Chen Y,Zhou M,Zhang H,Chen R,Shi F,Wang C,Rui Z

更新日期：2015-02-01 00:00:00

abstract：:We established a new cell line (ACCNS) from human adenoid cystic carcinoma (AdCC) of the maxilla, using tissue culture techniques and it has been successfully subcultured for more than 100 passages during 2 years. The population doubling time was approximately 39.2 h on a plastic dish. In type I collagen gel culture, ...

journal_title：Oncology reports

authors： Tanaka N,Urabe K,Hashitani S,Sakurai K,Urade M

更新日期：2007-02-01 00:00:00

abstract：:Patients with autosomal recessive primary microcephaly have a small but architecturally normal brain containing a reduced number of neurons. Microcephalin and ASPM are two of the genes causing this disease. Both are centrosomal proteins involved in cell cycle regulation. Whereas microcephalin is a component of the DNA...

journal_title：Oncology reports

authors： Hagemann C,Anacker J,Gerngras S,Kühnel S,Said HM,Patel R,Kämmerer U,Vordermark D,Roosen K,Vince GH

更新日期：2008-08-01 00:00:00

abstract：:The actual predictive value of oestrogen receptor (ER) beta for treatment decisions in breast cancer is still unclear. Retrospective studies using preoperative systemic therapy (PST) revealed that chemotherapy but also endocrine therapy can lead to alterations in expression levels of ERalpha and progesterone receptor ...

journal_title：Oncology reports

authors： Wurster M,Ruoff A,Meisner C,Seeger H,Vogel U,Juhasz-Böss I,Solomayer E,Wallwiener D,Fehm T,Neubauer H

更新日期：2010-09-01 00:00:00

abstract：:Targeted gene therapy needs to be implemented for future therapies to ensure efficient activity at the site of patient primary tumors or metastases without causing intolerable side-effects. One of the elements of gene therapy is vector, which includes viral and non-viral vector. In the present study, we constructed a ...

journal_title：Oncology reports

authors： Zuo Y,Liao S,Xu Z,Xie J,Huang W,Yu Z

更新日期：2014-12-01 00:00:00

abstract：:The incidence and associated mortality of melanoma continues to increase worldwide. At present, there is no curative therapy for advanced stage of melanoma. It is necessary to find new indicators of prognosis and therapeutic targets. Increasing evidence shows that miRNA can provide potential candidate biomarkers for m...

journal_title：Oncology reports

authors： Guo B,Hui Q,Zhang Y,Chang P,Tao K

更新日期：2016-10-01 00:00:00

abstract：:Eighteen primary human malignant mesotheliomas obtained from 18 patients were screened for point mutations and microdeletions/insertions in all exons of the tumour suppressor gene PTEN/MMAC1 by SSCP analysis. No mutation could be found. Our preliminary data indicate that disarrangements of PTEN/MMAC1 are at least not ...

journal_title：Oncology reports

authors： Papp T,Schipper H,Pemsel H,Unverricht M,Muller KM,Wiethege T,Schiffmann D,Rahman Q

更新日期：2001-11-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) are known to migrate to tumor tissues and to play an important role in cancer progression. However, the effects of MSCs on tumor progression remain controversial. The purpose of the present study was to detect the effects of human umbilical cord-derived MSCs (hUC‑MSCs) on the human breast...

journal_title：Oncology reports

authors： Li T,Zhang C,Ding Y,Zhai W,Liu K,Bu F,Tu T,Sun L,Zhu W,Zhou F,Qi W,Hu J,Chen H,Sun X

更新日期：2015-09-01 00:00:00

abstract：:Sarcosine is currently one of the most discussed markers of prostate cancer. It is involved in amino acid metabolism and methylation processes that occur during the progression of prostate cancer. In this study, we monitored the effect of the addition of sarcosine (0; 10; 250; 500; 1,000 and 1,500 µM) in a time-depend...

journal_title：Oncology reports

authors： Cernei N,Zitka O,Skalickova S,Gumulec J,Sztalmachova M,Rodrigo MA,Sochor J,Masarik M,Adam V,Hubalek J,Trnkova L,Kruseova J,Eckschlager T,Kizek R

更新日期：2013-06-01 00:00:00

abstract：:Recent research indicates that the Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) pathway may play an important role in chronic inflammation which promotes cancer progression, yet the mechanism is not clear. The present study aimed to investigate the role of the JAK/STAT3 pathway in the gr...

journal_title：Oncology reports

authors： Fang J,Chu L,Li C,Chen Y,Hu F,Zhang X,Zhao H,Liu Z,Xu Q

更新日期：2015-01-01 00:00:00

abstract：:Multigene-based combination therapy may be an effective practice in cancer gene therapy. Substantial studies have demonstrated that tumor suppressor p53 acetylation is indispensable for p53 activation. Inhibitor of growth 4 (ING4), as a novel tumor suppressor, is capable of remarkably enhancing p53 acetylation and its...

journal_title：Oncology reports

authors： Wu J,Zhu Y,Xu C,Xu H,Zhou X,Yang J,Xie Y,Tao M

更新日期：2016-01-01 00:00:00

abstract：:Identification of novel botanicals that can selectively induce apoptosis and arrest growth of cancer cells without producing cytotoxic effects is highly appreciable for cancer therapy. The present study aimed to investigate the possibility of acetylbritannilactone (ABL) derivative 5-(5-(ethylperoxy)pentan-2-yl)-6-meth...

journal_title：Oncology reports

authors： Zhang Y,Liu K,Zhang Y,Qi J,Lu B,Shi C,Yin Y,Cai W,Li W

更新日期：2015-12-01 00:00:00

abstract：:Although the impact of vascular endothelial growth factor (VEGF) is clearly established in advanced prostate cancer (PCa), its role in localized PCa remains to be determined. The aim of our study was to analyse the plasma levels of VEGF-A and the expression of VEGF-A in prostatic tissue in a population of patients wit...

journal_title：Oncology reports

authors： Peyromaure M,Badoual C,Camparo P,Grabar S,Goulvestre C,Fulla Y,Vieillefond A,Mao K,Dinh-Xuan AT

更新日期：2007-07-01 00:00:00

abstract：:Mast cell-derived chymase promotes inflammatory responses and tissue fibrosis. Although previous studies have reported changes in the number of mucosal mast cells in inflammatory bowel disease (IBD), the behaviour of chymase immunopositive mast cells has not been studied. In this study, we immunohistochemically invest...

journal_title：Oncology reports

authors： Andoh A,Deguchi Y,Inatomi O,Yagi Y,Bamba S,Tsujikawa T,Fujiyama Y

更新日期：2006-07-01 00:00:00

abstract：:In this study, a total of 108 patients with primary colorectal cancer who underwent hybrid 2-port hand-assisted laparoscopic surgery (HALS) were classified as 58 patients with colon cancer and 50 patients with rectal cancer. The mean operating time, mean blood loss, postoperative complications, and mean postoperative ...

journal_title：Oncology reports

authors： Mukai M,Kishima K,Tajima T,Hoshikawa T,Yazawa N,Fukumitsu H,Okada K,Ogoshi K,Makuuchi H

更新日期：2009-10-01 00:00:00