Low-voltage-activated ("T-Type") calcium channels in review.

abstract：:Two kinds of ATP binding sites were found on the ATPase molecule in deoxycholic acid-treated sarcoplasmic reticulum. One was the catalytic site (1 mol/mol active site) and its affinity was high. Upon addition of Ca2+, all the ATP bound to the catalytic site disappeared at 75 mM KCl, while a significant amount of ATP r...

journal_title：Journal of bioenergetics and biomembranes

authors： Nakamura Y,Tonomura Y

更新日期：1982-12-01 00:00:00

abstract：:Mitochondrial reactive oxygen species (ROS) production was investigated in mitochondria extracted from liver of rats treated with or without metformin, a mild inhibitor of respiratory chain complex 1 used in type 2 diabetes. A high rate of ROS production, fully suppressed by rotenone, was evidenced in non-phosphorylat...

journal_title：Journal of bioenergetics and biomembranes

authors： Batandier C,Guigas B,Detaille D,El-Mir MY,Fontaine E,Rigoulet M,Leverve XM

更新日期：2006-02-01 00:00:00

abstract：:At present there is a poor understanding of the events that lead up to neuronal apoptosis that occurs in neurodegenerative diseases and following acute ischemic episodes. Apoptosis is critical for the elimination of unwanted neurons within the developing nervous system. The Bcl-2 family of proteins contains pro- and a...

journal_title：Journal of bioenergetics and biomembranes

authors： Ward MW,Kögel D,Prehn JH

更新日期：2004-08-01 00:00:00

abstract：:Relevant Ca(2+) pools and fluxes in H9c2 cells have been studied using fluorescent indicators and Ca(2+)-mobilizing agents. Vasopressin produced a cytoplasmic Ca(2+) peak with half-maximal effective concentration of 6 nM, whereas thapsigargin-induced Ca(2+) increase showed half-maximal effect at 3 nM. Depolarization o...

journal_title：Journal of bioenergetics and biomembranes

authors： Lax A,Soler F,Fernández-Belda F

更新日期：2005-08-01 00:00:00

abstract：:The purification of the channel-forming component of the mitochondrial calcium uniporter and its channel properties are described. After ethanol and 50% ethanol-water extraction of mitochondria from beef heart or perfused rat liver, the extract was passed through thiopropyl-Sepharose 6B column, and absorbed components...

journal_title：Journal of bioenergetics and biomembranes

authors： Mironova GD,Baumann M,Kolomytkin O,Krasichkova Z,Berdimuratov A,Sirota T,Virtanen I,Saris NE

更新日期：1994-04-01 00:00:00

abstract：:Signal peptidases, the endoproteases that remove the amino-terminal signal sequence from many secretory proteins, have been isolated from various sources. Seven signal peptidases have been purified, two from E. coli, two from mammalian sources, and three from mitochondrial matrix. The mitochondrial enzymes are soluble...

journal_title：Journal of bioenergetics and biomembranes

authors： Dev IK,Ray PH

更新日期：1990-06-01 00:00:00

abstract：:Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) has been recently identified as a novel inhibitor of multiple tumors; however, its role in glioblastoma (GBM) has not been investigated. This study aimed to evaluate whether LHPP exerts a potential tumor-inhibiting role in GBM. Compared with tha...

journal_title：Journal of bioenergetics and biomembranes

authors： Li C,Yang J,Wang W,Li R

更新日期：2021-02-01 00:00:00

abstract：:We have previously shown that vacuolar H+-ATPase subcomplex V(o) from mung bean contains subunit d, however, its sequence and function were unknown. In the present study, we report the cloning and recombinant over expression of subunit d from mung bean in E. coli. To study the function of subunit d, two vacuolar H+-AT...

journal_title：Journal of bioenergetics and biomembranes

authors： Ouyang Z,Li Z,Zhang X

更新日期：2008-12-01 00:00:00

abstract：:Methylmalonic acidemia is one of the most prevalent inherited metabolic disorders involving neurological deficits. In vitro experiments, animal model studies and tissue analyses from human patients suggest extensive impairment of mitochondrial energy metabolism in this disease. This review summarizes changes in mitoch...

journal_title：Journal of bioenergetics and biomembranes

authors： Melo DR,Kowaltowski AJ,Wajner M,Castilho RF

更新日期：2011-02-01 00:00:00

abstract：:The ATP-binding cassette (ABC) family of membrane transport proteins is the largest class of transporters in humans (48 members). The majority of ABC transporters function at the cell surface. Therefore, defective folding and trafficking of the protein to the cell surface can lead to serious health problems. The class...

journal_title：Journal of bioenergetics and biomembranes

authors： Loo TW,Bartlett MC,Clarke DM

更新日期：2005-12-01 00:00:00

abstract：:Vacuolar H+ ATPases participate in renal hydrogen ion secretion in both the proximal and distal nephron. These plasma membrane forms of the vacuolar H+ ATPase are regulated physiologically to maintain the acid-base balance of the organism. Proton transporting renal cells have requirements for constitutive acidificatio...

journal_title：Journal of bioenergetics and biomembranes

authors： Gluck SL

更新日期：1992-08-01 00:00:00

abstract：:The electrolyte-pigment-metal system can be described as analogous to a photosensitive junction region. When the thickness of the pigment film is increased, the action spectra of the maximum short-circuit photo-current under continuous illumination differ from the absorption spectra both in direct illumination (pigmen...

journal_title：Journal of bioenergetics and biomembranes

authors： Villar JG

更新日期：1976-08-01 00:00:00

abstract：:We report on the influence of dielectric pulse injection on the energy metabolism of yeast cells with a planar interdigitated electrode interface. The energy metabolism was measured via NADH fluorescence. The application of dielectric pulses results in a distinct decrease of the fluorescence, indicating a response of ...

journal_title：Journal of bioenergetics and biomembranes

authors： Reiher A,Warnke C,Radoch S,Witte H,Krtschil A,Mair T,Müller SC,Krost A

更新日期：2006-04-01 00:00:00

abstract：:Liver mitochondria isolated from rats 24 h after a single subcutaneous injection of 8 mg thyroxine per kilogram body weight were compared with those isolated from control rats that received injections of isotonic saline at the same time. The mitochondria isolated from the thyroxine-treated rats show higher rates of en...

journal_title：Journal of bioenergetics and biomembranes

authors： Shears SB,Bronk JR

更新日期：1980-12-01 00:00:00

abstract：:Hepatic iron toxicity because of iron overload seems to be mediated by lipid peroxidation of biological membranes and the associated organelle dysfunctions. However, the basic mechanisms underlying this process in vivo are still little understood. Gerbils were dosed with weekly injections of iron-dextran alone or in c...

journal_title：Journal of bioenergetics and biomembranes

authors： Masini A,Ceccarelli D,Giovannini F,Montosi G,Garuti C,Pietrangelo A

更新日期：2000-04-01 00:00:00

abstract：:The chronology of the major discoveries important in elucidating certain aspects of the molecular basis of transmembrane signaling is briefly reviewed. Recent developments linking cell stimulation and transformation are intimated. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Badwey JA

更新日期：1991-02-01 00:00:00

abstract：:Liver plasma membranes isolated from rats with chronic dietary iron overload showed a large modification of their phospholipid fatty acid composition. Specifically, a significant decrease in polyunsaturated fatty acids and a parallel increase in saturated fatty acids was observed. This pattern was consistent with the ...

journal_title：Journal of bioenergetics and biomembranes

authors： Pietrangelo A,Tripodi A,Carulli N,Tomasi A,Ceccarelli D,Ventura E,Masini A

更新日期：1989-08-01 00:00:00

abstract：:The soxL gene from Sulfolobus acidocaldarius (DSM 639) encodes a Rieske iron-sulfur protein. In this study we report the identification of two open reading frames in its downstream region. The first one, named soxN, codes for a membrane protein bearing a resemblance to the b-type cytochromes of the cytochrome bc1 and ...

journal_title：Journal of bioenergetics and biomembranes

authors： Hiller A,Henninger T,Schäfer G,Schmidt CL

更新日期：2003-04-01 00:00:00

abstract：:Since the nineteenth century, a great amount of different biological structures and processes have been assessed by fluorescent dyes. Along with the uses of these compounds as vital and histological dyes, some fluorescent dyes have become valuable tools for the study of the pore phenomenon in plasma membranes. Some io...

journal_title：Journal of bioenergetics and biomembranes

authors： Ferreira L,Pereira L,Faria R

更新日期：2015-08-01 00:00:00

abstract：:The original version of this article unfortunately contained a mistake. The name of "Zohreh Noaparast" is now corrected in the author group of this article. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Hosseinimehr SJ,Safavi Z,Farahani SK,Noaparast Z,Ghasemi A,Asgarian-Omran H

更新日期：2019-08-01 00:00:00

abstract：:It is proven that any model of localized protonmotive energy coupling that relies upon properties of a homogeneous surface phase must, when operated in the steady state, lead to bulk phase electrochemical potentials for protons that are as large as those required by the delocalized chemiosmotic theory. To obtain model...

journal_title：Journal of bioenergetics and biomembranes

authors： Nagle JF,Dilley RA

更新日期：1986-02-01 00:00:00

abstract：:Electron microscopy (EM) in combination with image analysis is a powerful technique to study protein structure at low- and high resolution. Since electron micrographs of biological objects are very noisy, substantial improvement of image quality can be obtained by averaging individual projections. Crystallographic and...

journal_title：Journal of bioenergetics and biomembranes

authors： Boekema EJ,Boonstra AF,Dekker JP,Rögner M

更新日期：1994-02-01 00:00:00

abstract：:In this study we used tightly-coupled mitochondria from Yarrowia lipolytica and Dipodascus (Endomyces) magnusii yeasts. The two yeast strains are good alternatives to Saccharomyces cerevisiae, being aerobes containing well structured mitochondria (thus ensuring less structural limitation to observe their appreciable s...

journal_title：Journal of bioenergetics and biomembranes

authors： Trendeleva T,Sukhanova E,Ural'skaya L,Saris NE,Zvyagilskaya R

更新日期：2011-12-01 00:00:00

abstract：:Many oxidoreductases are constructed from (a) local sites of strongly coupled substrate-redox cofactor partners participating in exchange of electron pairs, (b) electron pair/single electron transducing redox centers, and (c) nonadiabatic, long-distance, single-electron tunneling between weakly coupled redox centers. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Moser CC,Page CC,Farid R,Dutton PL

更新日期：1995-06-01 00:00:00

abstract：:Recent advances in structural biology underlying mechanisms of channel gating have strengthened our knowledge about how K(+) channels can be inter-convertible between conductive and non-conductive states. We have reviewed and combined mutagenesis with biochemical, biophysical and structural information in order to und...

journal_title：Journal of bioenergetics and biomembranes

authors： Raja M,Olrichs NK,Vales E,Schrempf H

更新日期：2012-02-01 00:00:00

abstract：:The topology of beef heart Complex III has been studied by tryptic and chymotryptic digestion of isolated Complex III, Mg2+-ATP submitochondrial particles, and mitoplasts. Degradation products were detected by the immunoreplication technique using specific antibodies against core protein 1 (50 K) and core protein 2 (4...

journal_title：Journal of bioenergetics and biomembranes

authors： Mendel-Hartvig I,Nelson BD

更新日期：1983-02-01 00:00:00

abstract：:3-Bromopyruvate (3BP) is an energy-depleting drug that inhibits Hexokinase II activity by alkylation during glycolysis, thereby suppressing the production of ATP and inducing cell death. As such, 3BP can potentially serve as an anti-tumorigenic agent. Our previous research showed that 3BP can induce apoptosis via AKT ...

journal_title：Journal of bioenergetics and biomembranes

authors： Sun Y,Liu Z,Zou X,Lan Y,Sun X,Wang X,Zhao S,Jiang C,Liu H

更新日期：2015-08-01 00:00:00

abstract：:A sodium-dependent phosphate transporter (type II Na/Pi-cotransporter) was isolated which is expressed in apical membranes of proximal tubules and exhibits transport characteristics similar as described for renal reabsorption of phosphate. Type II associated Na/Pi-cotransport is electrogenic and results obtained by el...

journal_title：Journal of bioenergetics and biomembranes

authors： Biber J,Murer H,Forster I

更新日期：1998-04-01 00:00:00

abstract：:Affinity labeling and genetic studies on the glycine-rich sequence of the beta subunit of E. coli F-type ATPase are discussed. A model of the structure of the enzyme near the gamma phosphate moiety is proposed. ...

journal_title：Journal of bioenergetics and biomembranes

authors： Futai M,Iwamoto A,Omote H,Maeda M

更新日期：1992-10-01 00:00:00

abstract：:The importance of crucial nutrient factors like Phosphate (P) and their limited availability leads to variable fluctuations in fatty acid and phospholipid synthesis in the green alga. These fatty acids and phospholipids are an imperative byproduct of alga which used in biofuel production. The production of phospholipi...

journal_title：Journal of bioenergetics and biomembranes

authors： Qari HA,Oves M

更新日期：2020-02-01 00:00:00