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Plasticity of T cell memory responses to viruses.

Abstract：

:Virus-specific memory T cell populations demonstrate plasticity in antigenic and functional phenotype, in recognition of antigen, and in their ability to accommodate new memory T cell populations. The adaptability of complex antigen-specific T cell repertoires allows the host to respond to a diverse array of pathogens and accommodate memory pools to many pathogens in a finite immune system. This is in part accounted for by crossreactive memory T cells, which can be employed in immune responses and mediate protective immunity or life-threatening immunopathology.

journal_name

Immunity

journal_title

Immunity

authors

Selin LK,Welsh RM

doi

10.1016/s1074-7613(03)00356-x

keywords:

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

5-16

issue

1

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(03)00356-X

journal_volume

20

pub_type

杂志文章,评审

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