Expression of Vibrio vulnificus capsular polysaccharide inhibits biofilm formation.

Abstract:

:Vibrio vulnificus is a human pathogen that produces lethal septicemia in susceptible persons, and the primary virulence factor for this organism is capsular polysaccharide (CPS). The role of the capsule in V. vulnificus biofilms was examined under a variety of conditions, by using either defined CPS mutants or spontaneous CPS expression phase variants derived from multiple strains. CPS expression was shown to inhibit attachment and biofilm formation, which contrasted with other studies describing polysaccharides as integral to biofilms in related species.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

Joseph LA,Wright AC

doi

10.1128/jb.186.3.889-893.2004

keywords:

subject

Has Abstract

pub_date

2004-02-01 00:00:00

pages

889-93

issue

3

eissn

0021-9193

issn

1098-5530

journal_volume

186

pub_type

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