Abstract:
:Sudden cardiac death occurs as a result of a complex interplay of changes in myocardial substrate, imbalance of autonomic regulation of the heart, and myocardial vulnerability. Noninvasive electrocardiology serves as a comprehensive tool for investigating factors representing mechanistic pathways leading to cardiac events. Heart rate variability, nonlinear dynamics of heart rate, and heart rate turbulence provide insight into autonomic control of the heart. Prognostic value of these parameters in postinfarction patients is well established for predicting cardiac death, but there is less evidence for their association with sudden death or arrhythmic events. Electrical manifestation of changes in myocardial substrate include QRS and QTc prolongation, presence of conduction disturbances, presence of late potentials, abnormalities of repolarization morphology, and presence of nonsinus rhythm, namely atrial fibrillation. Electrocardiogram (ECG) measures reflecting myocardial vulnerability to arrhythmias include frequent ventricular premature beats, T wave alternans, or QT variability. Prognostic significance of these parameters is documented in studies focused mostly on them as individual markers of risk. The noninvasive electrocardiology substudy of the Multicenter Automatic Defibrillator Implantation Trial II (MADIT II) allows for simultaneous analysis of several of the above ECG markers of risk and will provide insight about relative contribution of mechanistic pathways leading to cardiac death in postinfarction patients with severe left ventricular dysfunction. Combination of a standard 12-lead ECG and 10-minute high-resolution Holter recordings serves to evaluate the prognostic significance of noninvasive electrocardiology parameters for mortality in patients randomized to conventional treatment and for arrhythmic events in patients randomized to implantable cardioverter defibrillator therapy.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Zareba W,Moss AJdoi
10.1016/j.jelectrocard.2003.09.022keywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
101-8eissn
0022-0736issn
1532-8430pii
S0022073603001109journal_volume
36 Supplpub_type
杂志文章,评审abstract::Methods currently exist for the precise measurement of local three-dimensional myocardial motion noninvasivly with magnetic resonace imaging tagging. From these motion estimates, strain images representing the local deformation of the myocardium can be formed to show local myocardial contraction. These images clearly ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2002.37156
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Our aim was to evaluate the intermittent use of a handheld ECG system for detecting silent arrhythmias and cardiac autonomic dysfunction in children with univentricular hearts. METHODS:Twenty-seven patients performed intermittent ECG recordings with handheld devices during a 14-day period. A manual arrhythm...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2014.02.006
更新日期:2014-05-01 00:00:00
abstract:INTRODUCTION:Measures of heart rate variability (HRV) can be divided in time domain and frequency domain parameters. It is frequently ignored that estimation of frequency-domain parameters is a 2-step procedure where statistical error from the first step (spectral estimation) is neglected in subsequent analyses. METHO...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2008.02.014
更新日期:2008-07-01 00:00:00
abstract::Sources of error in averaging for late ventricular potentials include variations in the magnitude and timing of late potentials as well as variability in the temporal alignment of successive cardiac cycles during averaging. Since these errors can both attenuate high frequency signals and add artifactual components to ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract:BACKGROUND:Atrial fibrillation occurs in 20% to 40% of patients post cardiac surgery. Prophylactic amiodarone decreases the incidence of atrial fibrillation, especially in those not taking β-blockers. Studies, however, vary in dosage, duration of treatment, and route of administration. Limited studies evaluating short ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jelectrocard.2012.07.005
更新日期:2012-11-01 00:00:00
abstract::The authors present a patient who initially underwent anterior approach atrioventricular (AV) nodal modification for treatment of typical AV junctional reentrant tachycardia (AVJRT) and subsequently developed clinical episodes of a previously undocumented type of supraventricular tachycardia. Findings during electroph...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(05)80113-x
更新日期:1994-01-01 00:00:00
abstract::There is increasing evidence that regular intense endurance exercise can promote structural and electrical remodeling of the right ventricle (RV). These physiological changes can be profound and are frequently accompanied by ECG changes in the right precordial leads, thereby mimicking features observed in arrhythmogen...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2015.03.001
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Reducing time to reperfusion treatment for patients with ST-segment elevation myocardial infarction (STEMI) improves patient outcomes. Few medical systems consistently meet current benchmarks regarding timely access to treatment. Studies have widely demonstrated that prehospital 12-lead electrocardiography c...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2009.03.011
更新日期:2009-09-01 00:00:00
abstract::A superficial accessory pathway was demonstrated by electrophysiologic techniques and surgical histopathology in 30-year-old male with Wolff-Parkinson-White syndrome, severe mitral valve disease and medically uncontrollable arrhythmias. In this patient, electrode catheter studies in the cardiac catheterization laborat...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(80)80093-8
更新日期:1980-10-01 00:00:00
abstract::This study is a descriptive report of the occurrence of ventricular arrhythmias in a large, prospectively designed follow-up study of postcoronary patients. Six-hour Holter recordings were obtained on 954 postinfarction patients prior to hospital discharge and at 4 (n = 837), 8 (n = 762), 12 (n = 713), and 24 (n = 487...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(80)80043-4
更新日期:1980-04-01 00:00:00
abstract:AIMS:The objective of the study was to develop normal limits of the ECG in an apparently healthy population of South Asians living in India. METHODS:Three centres contributed to recording 12 lead ECGs on identical digital electrocardiographs. Apparently healthy volunteers were recruited and ECGs were first transferred...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jelectrocard.2015.04.013
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Analysis of ST-segment elevation for assessment of patients with suspected acute coronary occlusion is in widespread use for diagnostic and prognostic purposes. In this study, changes in the QRS complex also were analyzed to determine if these changes that are seldom used clinically can provide additional pr...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2006.09.001
更新日期:2007-01-01 00:00:00
abstract::The electrocardiogram (ECG) is a relatively insensitive tool for the detection of right ventricular hypertrophy (RVH), but some criteria have high specificity. The recommended ECG screening criteria for RVH are not sufficiently sensitive or specific for screening for mild RVH in adults without clinical cardiovascular ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2017.09.004
更新日期:2018-01-01 00:00:00
abstract::Electrocardiographic estimation of myocardial injury has, in some studies, correlated poorly with the extent of nuclear perfusion defects at rest and with changes in the left ventricular ejection fraction after acute reperfusion therapy. The authors investigated 16 patients with fatty acid scintigraphy and with the Se...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(05)80256-0
更新日期:1995-07-01 00:00:00
abstract::An asymptomatic 19-year-old top-level athlete had electrocardiographic evidence of intermittent cardiac preexcitation and intermittent left bundle branch block. The electrophysiologic study demonstrated the presence of a direct accessory pathway and enhanced atrioventricular node conduction that resulted in infrahisia...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(91)90083-x
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:In STEMI, grade-3 ischemia (G3) on admission ECG predicts larger infarct size (IS) than grade-2 (G2). We evaluated whether pre-hospital G3 and its temporal behavior are associated with IS and salvage after pPCI. METHODS:In 401 STEMI patients, pre-hospital and pre-PCI ECGs were classified as G3 or G2. IS was...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jelectrocard.2014.04.012
更新日期:2014-07-01 00:00:00
abstract::Isomagnetic maps were recorded in normal subjects and in patients with systolic overloading of the right ventricle. The isomagnetic maps examined in this study indicated the instantaneous current source of the heart by applying the "corkscrew rule." The magnetic field recorded by a second derivative gradiometer detect...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(88)80013-x
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:Interatrial block (IAB; P waves >/= 110 milliseconds), the conduction delay between the right (RA) and left atrium (LA), is depicted on the electrocardiogram (ECG) as prolonged, often bifid ("notched"), P waves with distinguishable RA and LA components. Although electrophysiologic (EP) studies give some insi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2005.11.002
更新日期:2006-10-01 00:00:00
abstract::In the last 10 years the molecular substrate of a diversity of primary electrical diseases has been unraveled. Disease-causing mutations in ion-channel genes have been identified and have challenged clinical and basic electrophysiologists to mechanistically link the observed genetic aberrancies to the phenotype. Indee...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/j.jelectrocard.2005.06.103
更新日期:2005-10-01 00:00:00
abstract:INTRODUCTION:The mechanisms of torsade de pointes tachycardia (TdP) are incompletely understood. We aimed to investigate the mechanisms underlying TdP tachycardia in patients with spontaneous high-degree atrioventricular block (AVB). METHODS AND RESULTS:This retrospective study reviewed old TdP recordings after ventri...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2019.05.007
更新日期:2019-01-01 00:00:00
abstract::The authors present an original method for the discrimination of patients prone to ventricular tachycardia. The wavelet transform, which is a new time-scale technique suitable for transient signal detection, was applied to bipolar unfiltered X, Y, Z signal-averaged electrocardiograms in 20 postinfarction patients with...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(93)90052-f
更新日期:1993-10-01 00:00:00
abstract::We recently reported that signal averaged electrocardiograms (SAECG) measurements possess a circadian rhythm and are closely related to heart rate or heart rate variability in healthy volunteers. This study determines the influence of autonomic tone on the filtered QRS (f-QRS) duration from SAECG by using pharmacologi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(00)80096-5
更新日期:2000-01-01 00:00:00
abstract::This is the first report on the stable occurrence of ventricular quadrigeminy as a manifestation of concealed bigeminy in a case of fixed and late coupled ventricular extrasystoles. A 46-year-old man is reported in whom the period of ventricular bigeminy alternated with the period of ventricular quadrigeminy. Coupling...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1016/s0022-0736(00)80106-5
更新日期:2000-01-01 00:00:00
abstract::Central venous catheters extending into intracardiac chambers can provoke premature atrial and ventricular complexes, which have been reported to initiate supraventricular tachyarrhythmias. These catheters are traditionally placed via the femoral, subclavian, or internal jugular veins. A new alternative to the convent...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(96)80116-6
更新日期:1996-01-01 00:00:00
abstract::Placement of the precordial electrodes for recording a 12-lead electrocardiogram (ECG) is subject to variation. Previous research has shown that displacement, especially in the longitudinal direction, can lead to changes in diagnosis. In practice, both the displacement and the effects of displacement on an individual ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(96)80002-1
更新日期:1996-01-01 00:00:00
abstract::Voltage-sensitive dyes and high resolution optical mapping were used to analyze the characteristics of spiral waves of excitation in isolated ventricular myocardium. In addition, analytical techniques, which have been previously used in the study of the characteristics of spiral waves in chemical reactions, were appli...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(10)80029-9
更新日期:1992-01-01 00:00:00
abstract::An inexpensive system was developed for automated on-line analysis of ST segment heights, Q, R, and S heights and areas under these peaks, using an LSI-11 microcomputer. System accuracy was evaluated using a computer graphics technique which enabled magnification and labelling of the computed peaks on 60 maps from 17 ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(82)80032-0
更新日期:1982-01-01 00:00:00
abstract::Implantable cardioverter defibrillators (ICDs) detect and defibrillate ventricular fibrillation (VF) and ventricular tachycardia (VT). Other therapies which use less energy are also available to terminate VT. Previous studies have shown that ICD rate schemes often misdiagnose VT as VF. In this study, an improved VF cl...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(98)80060-5
更新日期:1998-01-01 00:00:00
abstract::In a patient with the sick sinus syndrome and near syncope a prolonged sinus pause was documented and reproduced thereafter during sustained deep inspiration. Administration of intravenous atropine abolished this phenomenon, most probably indicating a hyperresponsiveness of the sinus node and AV junction to a vagotoni...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(86)80012-7
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:It has been reported in the literature that the increase in body temperature shortens QT interval on electrocardiogram through heart rate modulation. However, the effects of fever on ventricular repolarization are not clearly known. This study elaborates on QT interval of isolated fever, corrected QT (cQT), ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2020.11.016
更新日期:2020-12-03 00:00:00