Abstract:
:The mitochondrial alternative oxidase is a diiron carboxylate quinol oxidase (Dox) found in plants and some fungi and protists, but not animals. The plastid terminal oxidase is distantly related to alternative oxidase and is most likely also a Dox protein. Database searches revealed that the alpha-proteobacterium Novosphingobium aromaticivorans and the cyanobacteria Nostoc sp. PCC7120, Synechococcus sp. WH8102 and Prochlorococcus marinus subsp. pastoris CCMP1378 each possess a Dox homolog. Each prokaryotic protein conforms to the current structural models of the Dox active site and phylogenetic analyses suggest that the eukaryotic Dox genes arose from an ancestral prokaryotic gene.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Finnegan PM,Umbach AL,Wilce JAdoi
10.1016/s0014-5793(03)01309-7keywords:
subject
Has Abstractpub_date
2003-12-18 00:00:00pages
425-30issue
3eissn
0014-5793issn
1873-3468pii
S0014579303013097journal_volume
555pub_type
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