Human peripheral blood lymphocytes express D5 dopamine receptor gene and transcribe the two pseudogenes.

Abstract:

:Sequential reverse transcription and polymerase chain reaction (RT-PCR) of the mRNA were used to investigate the expression of dopamine receptors in human peripheral blood lymphocytes. The RT-PCR products contained three types of sequences, each corresponding to those of the D5 dopamine receptor gene and the two related pseudogenes. The lymphocyte cDNA library also contained the clones encoding parts of the three genes. Binding profiles of dopaminergic ligands to the lymphocytes were similar to those for the native neuronal membranes.

journal_name

FEBS Lett

journal_title

FEBS letters

authors

Takahashi N,Nagai Y,Ueno S,Saeki Y,Yanagihara T

doi

10.1016/0014-5793(92)81452-r

keywords:

subject

Has Abstract

pub_date

1992-12-07 00:00:00

pages

23-5

issue

1

eissn

0014-5793

issn

1873-3468

pii

0014-5793(92)81452-R

journal_volume

314

pub_type

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