Abstract:
:Uncouplers are molecules with protonophoric and ionophoric capabilities that mediate coupled cyclical transport of cations--a transport that takes precedence over all other coupled processes. Uncouplers form cation-containing complexes with electrogenic ionophores that potentiate cyclical transport of cations. The molecular mechanism of uncoupling sheds strong light on the mechanism of coupling.
journal_name
Proc Natl Acad Sci U S Aauthors
Kessler RJ,Vande Zande H,Tyson CA,Blondin GA,Fairfield J,Glasser P,Green DEdoi
10.1073/pnas.74.6.2241keywords:
subject
Has Abstractpub_date
1977-06-01 00:00:00pages
2241-5issue
6eissn
0027-8424issn
1091-6490journal_volume
74pub_type
杂志文章abstract::In his Philosophical Investigations, Wittgenstein famously noted that the formation of semantic representations requires more than a simple combination of verbal and nonverbal features to generate conceptually based similarities and differences. Classical and contemporary neuroscience has tended to focus upon how diff...
journal_title:Proceedings of the National Academy of Sciences of the United States of America
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abstract::Look-through mutagenesis (LTM) is a multidimensional mutagenesis method that simultaneously assesses and optimizes combinatorial mutations of selected amino acids. The process focuses on a precise distribution within one or more complementarity determining region (CDR) domains and explores the synergistic contribution...
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abstract::The mature gag and pol proteins of human immunodeficiency virus (HIV) and all retroviruses derive from large gag and gag-pol polyprotein precursors by posttranslational cleavage. A highly specific, virally encoded protease is required for this essential proteolytic processing. In this study, the HIV protease gene prod...
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journal_title:Proceedings of the National Academy of Sciences of the United States of America
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更新日期:2019-05-14 00:00:00
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journal_title:Proceedings of the National Academy of Sciences of the United States of America
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journal_title:Proceedings of the National Academy of Sciences of the United States of America
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更新日期:2002-03-19 00:00:00