NEW TYPE OF STREPTOMYCIN RESISTANCE RESULTING FROM ACTION OF THE EPISOMELIKE MUTATOR FACTOR IN ESCHERICHIA COLI.

Abstract:

:Gundersen, Wenche B. (Oslo University, Oslo, Norway). New type of streptomycin resistance resulting from action of the episomelike mutator factor in Escherichia coli. J. Bacteriol. 86:510-516. 1963.-Analyses have been performed to elucidate the genetic nature of the streptomycin resistance that results from the action of the previously described episomelike mutator factor in Escherichia coli. This streptomycin resistance has been found to differ from ordinary one-step streptomycin resistance. The new type of streptomycin resistance, "mutator resistance," can be lost, either spontaneously or by treatment with ultraviolet light and acriflavine. It is more stable in a K-12 strain than in the original E. coli strain 635. Mutator resistance segregates like a chromosomal marker in genetic crosses, and is located near the ordinary streptomycin locus. The locus for mutator resistance is distinct from that of ordinary streptomycin resistance, apparently located further toward the threonine region. Mutator resistance, unlike ordinary one-step streptomycin resistance, appears as a dominant character. The possibilities of its being a suppressor or regulator mutation are discussed.

journal_name

J Bacteriol

journal_title

Journal of bacteriology

authors

GUNDERSEN WB

doi

10.1128/JB.86.3.510-516.1963

keywords:

subject

Has Abstract

pub_date

1963-09-01 00:00:00

pages

510-6

eissn

0021-9193

issn

1098-5530

journal_volume

86

pub_type

杂志文章
  • Isolation and characterization of mutants of colicin plasmids E1 and E2 after Mu bacteriophage infection.

    abstract::Cells colicinogenic for the colicin plasmids E1 or E2 (Col E1 and Col E2, respectively) were selected for a loss of colicin production after infection with bacteriophage Mu. Extrachromosomal deoxyribonucleic acid that was larger than the original colicin plasmids was found in such cells. A small insertion mutant in Co...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.119.2.469-477.1974

    authors: Inselburg J

    更新日期:1974-08-01 00:00:00

  • Cloning, nucleotide sequence, and overexpression of the gene coding for delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.

    abstract::The structural gene coding for the delta 5-3-ketosteroid isomerase (KSI) of Pseudomonas putida biotype B has been cloned, and its entire nucleotide sequence has been determined by a dideoxynucleotide chain termination method. A 2.1-kb DNA fragment containing the ksi gene was cloned from a P. putida biotype B genomic l...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.176.21.6672-6676.1994

    authors: Kim SW,Kim CY,Benisek WF,Choi KY

    更新日期:1994-11-01 00:00:00

  • The leucine-responsive regulatory protein, Lrp, modulates microcin J25 intrinsic resistance in Escherichia coli by regulating expression of the YojI microcin exporter.

    abstract::Many Escherichia coli K-12 strains display an intrinsic resistance to the peptide antibiotic microcin J25. In this study, we present results showing that the leucine-responsive regulatory protein, Lrp, is involved in this phenotype by acting as a positive regulator of YojI, a chromosomally encoded efflux pump which ex...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.01074-08

    authors: Socías SB,Vincent PA,Salomón RA

    更新日期:2009-02-01 00:00:00

  • Isolation and characterization of the Neurospora crassa endoplasmic reticulum.

    abstract::The endoplasmic reticulum from Neurospora crassa was identified by monitoring the activity of the putative enzyme marker phosphatidylcholine glyceride transferase. After differential centrifugation of a cell homogenate, phosphatidylcholine glyceride transferase activity initially copurified with plasma membrane H+-ATP...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.156.1.362-368.1983

    authors: Borgeson CE,Bowman BJ

    更新日期:1983-10-01 00:00:00

  • Influences of growth substrates and oxygen on the electron transport system in Acinetobacter sp. HO1-N.

    abstract::The electron transport system of Acinetobacter sp. HO1-N was studied to determine the specific cytochromes and to measure changes in the composition of the respiratory system due to growth in various concentrations of oxygen or types of growth substrates. Spectrophotometric analysis revealed that the quantity and type...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.142.3.859-868.1980

    authors: Ensley BD Jr,Finnerty WR

    更新日期:1980-06-01 00:00:00

  • Asymmetric expression of the gyrase B gene from the replication-competent chromosome in the Caulobacter crescentus predivisional cell.

    abstract::The bacterium Caulobacter crescentus undergoes an asymmetric cell division resulting in the formation of two different daughter cells, a motile swarmer cell and a nonmotile stalked cell. These two cell types differ in their program of gene expression, their ability to replicate DNA, and the physical properties of thei...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.175.21.6970-6981.1993

    authors: Rizzo MF,Shapiro L,Gober J

    更新日期:1993-11-01 00:00:00

  • Heme and a five-amino-acid hemophore region form the bipartite stimulus triggering the has signaling cascade.

    abstract::Bacterial cells sense the extracellular environment and adapt to that environment by activating gene regulation circuits, often by means of signaling molecules. The Serratia marcescens hemophore is a signaling molecule that acts as an extracellular heme-scavenging protein. The heme-loaded hemophore interacts with its ...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.188.9.3357-3364.2006

    authors: Cwerman H,Wandersman C,Biville F

    更新日期:2006-05-01 00:00:00

  • Caulobacter flagellar organelle: synthesis, compartmentation, and assembly.

    abstract::In Caulobacter crescentus biogenesis of the flagellar organelle occurs during one stage of its complex life cycle. Thus in synchronous cultures it is possible to assay the sequential synthesis and assembly of the flagellum and hook in vivo with a combination of biochemical and radioimmunological techniques. The period...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.135.3.1062-1069.1978

    authors: Lagenaur C,Agabian N

    更新日期:1978-09-01 00:00:00

  • Regulation of Salmonella typhimurium ilvYC genes.

    abstract::The Salmonella typhimurium LT2 ilvYC genes were studied by fusion of each gene to the Escherichia coli K-12 galK gene. The expression of ilvY and ilvC could then be determined by measurement of the galK-encoded galactokinase enzyme. The promoter for ilvC, pC, was located by this technique to a 0.42-kilobase BglII-EcoR...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.159.3.951-957.1984

    authors: Blazey DL,Burns RO

    更新日期:1984-09-01 00:00:00

  • Indirect selection of bacterial plasmids lacking identifiable phenotypic properties.

    abstract::A procedure is described that uses an indicator plasmid (pSC201) to identify cells in a bacterial population that have been co-transformed with a second plasmid lacking detectable phenotypic properties. Under appropriate conditions of indirect selection, between 50 and 85% of transformants carrying the indicator plasm...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.124.1.225-231.1975

    authors: Kretschmer FJ,Chang AC,Cohen SN

    更新日期:1975-10-01 00:00:00

  • Role of a ferredoxin gene cotranscribed with the nifHDK operon in N(2) fixation and nitrogenase "switch-off" of Azoarcus sp. strain BH72.

    abstract::The endophytic diazotroph Azoarcus sp. strain BH72 is capable of infecting rice roots and of expressing the nitrogenase (nif) genes there. In order to study the genetic background for nitrogen fixation in strain BH72, the structural genes of nitrogenase (nifHDK) were cloned and sequenced. The sequence analysis reveale...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.183.12.3752-3760.2001

    authors: Egener T,Martin DE,Sarkar A,Reinhold-Hurek B

    更新日期:2001-06-01 00:00:00

  • Functions in outer and inner membranes of Escherichia coli for ferrichrome transport.

    abstract::Mutants of the fhuA gene of Escherichia coli K-12, which encodes a receptor protein in the outer membrane, took up ferrichrome after exposure to pronase, whereas fhuB mutants remained transport negative. The latter finding supports our previous proposal that fhuB mutants are defective in a function that residues in th...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.146.3.1158-1161.1981

    authors: Wookey PJ,Hussein S,Braun V

    更新日期:1981-06-01 00:00:00

  • Intracellular concentrations of 65 species of transcription factors with known regulatory functions in Escherichia coli.

    abstract::The expression pattern of the Escherichia coli genome is controlled in part by regulating the utilization of a limited number of RNA polymerases among a total of its approximately 4,600 genes. The distribution pattern of RNA polymerase changes from modulation of two types of protein-protein interactions: the interacti...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.01579-14

    authors: Ishihama A,Kori A,Koshio E,Yamada K,Maeda H,Shimada T,Makinoshima H,Iwata A,Fujita N

    更新日期:2014-08-01 00:00:00

  • Effects of Dimethylsulfoxide on the Lactose Operon in Escherichia coli.

    abstract::Fowler, Audree V. (University of California, Los Angeles), and Irving Zabin. Effects of dimethylsulfoxide on the lactose operon in Escherichia coli. J. Bacteriol. 92:353-357. 1966.-Dimethylsulfoxide (DMSO) at a concentration of 5% (v/v) in the culture medium inhibits the growth of Escherichia coli to only a slight ext...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.92.2.353-357.1966

    authors: Fowler AV,Zabin I

    更新日期:1966-08-01 00:00:00

  • Conditional synthesis and utilization of 1,5-anhydroglucitol in Escherichia coli.

    abstract::A cyclic polyol, 1,5-anhydro-D-glucitol (AG), is widely detected in most organisms, although little is known about its metabolism and physiological roles. The present study demonstrates the synthesis of AG in Escherichia coli C600. The major portion of the synthesized AG was indicated to be derived from glucose retain...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.175.22.7138-7141.1993

    authors: Shiga Y,Mizuno H,Akanuma H

    更新日期:1993-11-01 00:00:00

  • Cloning and heterologous expression of the entire gene clusters for PD 116740 from Streptomyces strain WP 4669 and tetrangulol and tetrangomycin from Streptomyces rimosus NRRL 3016.

    abstract::The genes for the complete pathways for two polycyclic aromatic polyketides of the angucyclinone class have been cloned and heterologously expressed. Genomic DNAs of Streptomyces rimosus NRRL 3016 and Streptomyces strain WP 4669 were partially digested with MboI, and libraries (ca. 40-kb fragments) in Escherichia coli...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.179.2.470-476.1997

    authors: Hong ST,Carney JR,Gould SJ

    更新日期:1997-01-01 00:00:00

  • Genetic control of the rate of alpha-amylase synthesis in Bacillus subtilis.

    abstract::The level of extracellular alpha-amylase (EC 3.2.1.1) of Bacillus subtilis Marburg was increased about fivefold by introducing the amyR marker from B. natto 1212 through transformation. amyR2 of B. natto 1212 has been assumed to determine a high level of alpha-amylase of the organism. The gene acts specifically on alp...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.119.2.410-415.1974

    authors: Yamaguchi K,Nagata Y,Maruo B

    更新日期:1974-08-01 00:00:00

  • Secondary and tertiary responses of the induced bactericidin from the West Indian spiny lobster, Panulirus argus.

    abstract::West Indian spiny lobsters, Panulirus argus, synthesized a hemolymph bactericidin after being injected with killed suspensions of gram-negative bacillus EMB-1 isolated from the normal gut of this lobster. To study differences between the primary response and secondary response, animals were given a primary antigen inj...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.98.3.943-946.1969

    authors: Evans EE,Weinheimer PF,Painter B,Acton RT,Evans ML

    更新日期:1969-06-01 00:00:00

  • Cloning and genetic characterization of Helicobacter pylori catalase and construction of a catalase-deficient mutant strain.

    abstract::The N-terminal sequence of a protein, originally described as an adhesin of Helicobacter pylori, was used in an oligonucleotide-based screening procedure of an H. pylori plasmid library in Escherichia coli. Five independent plasmid clones were isolated, all mapping to the same chromosomal region and encoding the H. py...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.178.23.6960-6967.1996

    authors: Odenbreit S,Wieland B,Haas R

    更新日期:1996-12-01 00:00:00

  • Function of alpha-D-glucosyl monophosphorylpolyprenol in biosynthesis of cell wall teichoic acids in Bacillus coagulans.

    abstract::D-[alpha-14C]]glucosyl phosphorylpolyprenol ([ 14C]Glc-P-prenol) was formed from UDP-D-[14C]glucose in each of the membrane systems obtained from Bacillus coagulans AHU 1631 and AHU 1634 and two Bacillus megaterium strains. Membranes of these B. coagulans strains, which possess beta-D-glucosyl branches on the repeatin...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.171.5.2835-2841.1989

    authors: Shimada A,Tamatukuri J,Ito E

    更新日期:1989-05-01 00:00:00

  • Cell-Biological Studies of Osmotic Shock Response in Streptomyces spp.

    abstract::Most bacteria are likely to face osmotic challenges, but there is yet much to learn about how such environmental changes affect the architecture of bacterial cells. Here, we report a cell-biological study in model organisms of the genus Streptomyces, which are actinobacteria that grow in a highly polarized fashion to ...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.00465-16

    authors: Fuchino K,Flärdh K,Dyson P,Ausmees N

    更新日期:2016-12-13 00:00:00

  • Escherichia coli alkaline phosphatase fails to acquire disulfide bonds when retained in the cytoplasm.

    abstract::The cysteines of the Escherichia coli periplasmic enzyme alkaline phosphatase, which are involved in disulfide bonds in the native enzyme, were found to be fully reduced when the protein was retained in the cytoplasm. Under these circumstances the cysteines remained reduced for at least several minutes after the synth...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.173.23.7719-7722.1991

    authors: Derman AI,Beckwith J

    更新日期:1991-12-01 00:00:00

  • Expression of the Bacillus subtilis acsA gene: position and sequence context affect cre-mediated carbon catabolite repression.

    abstract::In Bacillus subtilis, carbon catabolite repression (CCR) of many genes is mediated at cis-acting carbon repression elements (cre) by the catabolite repressor protein CcpA. Mutations in transcription-repair coupling factor (mfd) partially relieve CCR at cre sites located downstream of transcriptional start sites by abo...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.180.24.6649-6654.1998

    authors: Zalieckas JM,Wray LV Jr,Fisher SH

    更新日期:1998-12-01 00:00:00

  • PilMNOPQ from the Pseudomonas aeruginosa type IV pilus system form a transenvelope protein interaction network that interacts with PilA.

    abstract::Pseudomonas aeruginosa type IV pili (T4P) are virulence factors that promote infection of cystic fibrosis and immunosuppressed patients. As the absence of T4P impairs colonization, they are attractive targets for the development of novel therapeutics. Genes in the pilMNOPQ operon are important for both T4P assembly an...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.00032-13

    authors: Tammam S,Sampaleanu LM,Koo J,Manoharan K,Daubaras M,Burrows LL,Howell PL

    更新日期:2013-05-01 00:00:00

  • Role of gene fadR in Escherichia coli acetate metabolism.

    abstract::Mutants of Escherichia coli K-12 constitutive for fatty acid degradation (fadR) showed an increased rate of utilization of exogenous acetate. Acetate transport, oxidation, and incorporation into macromolecules was approximately fivefold greater in fadR mutants than fadR+ strains during growth on succinate as a carbon ...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.148.1.83-90.1981

    authors: Maloy SR,Nunn WD

    更新日期:1981-10-01 00:00:00

  • DNA binding sites of the LysR-type regulator GcvA in the gcv and gcvA control regions of Escherichia coli.

    abstract::The GcvA protein is a LysR family regulatory protein necessary for both activation and repression of the Escherichia coli glycine cleavage enzyme operon (gcv) and negative regulation of gcvA. Gel shift assays indicated that overexpressed GcvA in crude extracts is capable of binding specifically to DNA containing the g...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.177.17.4940-4946.1995

    authors: Wilson RL,Urbanowski ML,Stauffer GV

    更新日期:1995-09-01 00:00:00

  • The Proline Variant of the W[F/L/M][T/S]R Cyclic Di-GMP Binding Motif Suppresses Dependence on Signal Association for Regulator Function.

    abstract::Vibrio vulnificus is an estuarine bacterium and potent opportunistic human pathogen. It enters the food chain by asymptomatically colonizing a variety of marine organisms, most notably oysters. Expression of the brp-encoded extracellular polysaccharide, which enhances cell-surface adherence, is regulated by cyclic di-...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.00344-17

    authors: Chodur DM,Guo L,Pu M,Bruger E,Fernandez N,Waters C,Rowe-Magnus DA

    更新日期:2017-09-05 00:00:00

  • Acceleration of starvation- and glycerol-induced myxospore formation by prior heat shock in Myxococcus xanthus.

    abstract::The effect of heat shock on Myxococcus xanthus was investigated during both glycerol- and starvation-induced development. Cells heat shocked at 40 degrees C for 1 h prior to a development-inducing signal displayed an accelerated rate of myxospore formation at 30 degrees C. Additionally, M. xanthus cells heat shocked p...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/jb.170.11.5200-5207.1988

    authors: Killeen KP,Nelson DR

    更新日期:1988-11-01 00:00:00

  • The autolysin LytA contributes to efficient bacteriophage progeny release in Streptococcus pneumoniae.

    abstract::Most bacteriophages (phages) release their progeny through the action of holins that form lesions in the cytoplasmic membrane and lysins that degrade the bacterial peptidoglycan. Although the function of each protein is well established in phages infecting Streptococcus pneumoniae, the role--if any--of the powerful ba...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.00477-09

    authors: Frias MJ,Melo-Cristino J,Ramirez M

    更新日期:2009-09-01 00:00:00

  • Subapical wall synthesis and wall thickening induced by cycloheximide in hyphae of Aspergillus nidulans.

    abstract::Hyphae of Aspergillus nidulans continued to synthesize all the major polysaccharide components of the cell wall when cycloheximide was added to cultures. In the presence of cycloheximide, hyphae did not elongate, but electron microscopy showed that the walls became thicker around the cell. The conclusion that cyclohex...

    journal_title:Journal of bacteriology

    pub_type: 杂志文章

    doi:10.1128/JB.114.2.819-823.1973

    authors: Sternlicht E,Katz D,Rosenberger RF

    更新日期:1973-05-01 00:00:00