Abstract:
:Das, S. K. (University of Calcutta, Calcutta, India) and G. C. Chatterjee. Pyrithiamine adaptation of Staphylococcus aureus. I. Adaptation and carbohydrate utilization. J. Bacteriol. 83:1251-1259. 1962.-Staphylococcus aureus has been adapted to pyrithiamine, a thiamine analogue; as a result of this adaptation, the color of the pigment of the organism changes from orange-yellow to lemon-yellow. The adaptation is reversible; the adapted strain will revert after repeated subculture in a medium containing thiamine and no pyrithiamine. Of the major biochemical alterations resulting from adaptation, severe depression in glucose utilization and simultaneous stimulation of acetate utilization have been noticed. The effect of metabolic inhibitors on the utilization of glucose and acetate has also been studied. By measuring the rate of formation of C(14)O(2) from glucose-1-C(14) and glucose-6-C(14), it has been observed that the reduction in C(14)O(2) formation from glucose-1-C(14) by the adapted organism is much more than that obtained from glucose-6-C(14), causing thereby a decreased metabolic ratio of these two substrates after such adaptation. Relative to the normal strain, the adapted strain utilizes acetate-C(14) at a much faster rate, both in the formation of C(14)O(2) and also in the incorporation of C(14) into the protein and lipid fractions; the rate of formation of C(14)O(2) from pyruvate-1-C(14) is not greatly altered. It has been postulated that there is a partial blocking of the pentose phosphate cycle, because of the lowered glucose-1-C(14) utilization, and simultaneous stimulation of the tricarboxylic acid cycle; or perhaps the initiation of some other route after pyrithiamine adaptation would account for the great increase in acetate utilization.
journal_name
J Bacterioljournal_title
Journal of bacteriologyauthors
DAS SK,CHATTERJEE GCdoi
10.1128/JB.83.6.1251-1259.1962keywords:
subject
Has Abstractpub_date
1962-06-01 00:00:00pages
1251-9eissn
0021-9193issn
1098-5530journal_volume
83pub_type
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journal_title:Journal of bacteriology
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doi:10.1128/JB.180.9.2468-2474.1998
更新日期:1998-05-01 00:00:00
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更新日期:1982-06-01 00:00:00
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journal_title:Journal of bacteriology
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更新日期:1993-01-01 00:00:00
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journal_title:Journal of bacteriology
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doi:10.1128/JB.123.2.755-758.1975
更新日期:1975-08-01 00:00:00
abstract::Gundersen, Wenche B. (Oslo University, Oslo, Norway). New type of streptomycin resistance resulting from action of the episomelike mutator factor in Escherichia coli. J. Bacteriol. 86:510-516. 1963.-Analyses have been performed to elucidate the genetic nature of the streptomycin resistance that results from the action...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.86.3.510-516.1963
更新日期:1963-09-01 00:00:00
abstract::The structural gene for histidyl-tRNA synthetase was localized to 53.8 min on the Escherichia coli genome. The gene order in this region was determined to be dapE-purC-upp-purG-(guaA, guaB)-hisS-glyA. ...
journal_title:Journal of bacteriology
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doi:10.1128/JB.138.1.264-267.1979
更新日期:1979-04-01 00:00:00
abstract::Gartner, T. K. (University of California, Santa Barbara), and E. Orias. Effects of mutations to streptomycin resistance on the rate of translation of mutant genetic information. J. Bacteriol. 91:1021-1028. 1966.-The effects of mutations to streptomycin resistance of independent origin upon the translation of suppressi...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.91.3.1021-1028.1966
更新日期:1966-03-01 00:00:00
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journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/jb.176.7.2013-2020.1994
更新日期:1994-04-01 00:00:00
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journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.01251-09
更新日期:2010-03-01 00:00:00
abstract::The autolytic capacity of Streptococcus faecium (S. faecalis ATCC 9790) varied during synchronous cell division. This phenomenon was initially observed in rapidly dividing populations (TD=30 to 33 min) synchronized by a combination of induction and size selection techniques. To minimize the problems inherent in studie...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.133.2.822-829.1978
更新日期:1978-02-01 00:00:00
abstract::Eight species representative of the serological diversity of the Mycoplasmatales were tested for their ability to incorporate radiolabeled nucleic acid precursors into acid-insoluble material. Cultures in complex growth medium were centrifuged and resuspended in minimal essential medium (Eagle). For Acholeplasma laidl...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.135.2.483-489.1978
更新日期:1978-08-01 00:00:00
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更新日期:2007-02-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.02057-12
更新日期:2013-03-01 00:00:00
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journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/jb.179.16.5165-5170.1997
更新日期:1997-08-01 00:00:00
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journal_title:Journal of bacteriology
pub_type: 杂志文章
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更新日期:2011-10-01 00:00:00
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更新日期:1990-02-01 00:00:00
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journal_title:Journal of bacteriology
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更新日期:2011-03-01 00:00:00
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更新日期:2009-01-01 00:00:00
abstract::The current work by Jain et al. (S. Jain, A. M. Chang, M. Singh, J. S. McLean, et al., J Bacteriol 201:e00683-18, 2019, https://doi.org/10.1128/JB.00683-18) reports the cloning of the lipid A deacylase gene of Porphyromonas gingivalis and the phenotypic characterization of the enzyme. Attempts to clone the gene and th...
journal_title:Journal of bacteriology
pub_type: 评论,杂志文章
doi:10.1128/JB.00146-19
更新日期:2019-05-08 00:00:00
abstract::Streptococcus suis serotype 2 (S. suis 2) is an important swine and human pathogen responsible for septicemia and meningitis. A novel gene, designated atl and encoding a major autolysin of S. suis 2 virulent strain HA9801, was identified and characterized in this study. The Atl protein contains 1,025 amino acids with ...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.06231-11
更新日期:2012-03-01 00:00:00
abstract::Numerous field isolates of Moraxella bovis have previously been classified by serological techniques into seven serogroups, each defined by homologous cross-reaction with antisera prepared against purified pili of a single prototype strain. The gene encoding pilin from each of the prototype strains has been characteri...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/jb.176.16.4875-4882.1994
更新日期:1994-08-01 00:00:00
abstract::The biodegradative threonine dehydratase (tdc) operon was mapped at 68 min on the Escherichia coli K-12 chromosome. The order of markers in the clockwise direction was dnaG uxaA tdc argG. A tdc deletion was isolated and mapped to this region of the chromosome. By using a tdcB-lacZ fusion the clockwise direction of tra...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/jb.170.11.5360-5363.1988
更新日期:1988-11-01 00:00:00
abstract::Mutants of Escherichia coli K-12 unable to excise pyrimidine dimers from their deoxyribonucleic acid (DNA) because of a uvr mutation show a higher survival when plated on a minimal salts medium after exposure to ultraviolet radiation than when plated on a complex medium such as nutrient agar containing yeast extract. ...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.102.2.404-410.1970
更新日期:1970-05-01 00:00:00
abstract::Rebers, P. A. (Rutgers, The State University, New Brunswick, N. J.), E. Hurwitz, M. Heidelberger, and S. Estrada-Parra. Immunochemistry of the pneumococcal types II, V, and VI. III. Tests with derivatives of the specific polysaccharides of types II and VI. J. Bacteriol. 83:335-342. 1962.-The type-specific pneumococcal...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.83.2.335-342.1962
更新日期:1962-02-01 00:00:00
abstract::Nishida, S. (Kanazawa University, Kanazawa, Japan), and G. Nakagawara. Isolation of toxigenic strains of Clostridium novyi from soil. J. Bacteriol. 88:1636-1640. 1964.-The cultural conditions for toxin production by Clostridium novyi were investigated, and the optimal constituents of a proper medium were determined. A...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.88.6.1636-1640.1964
更新日期:1964-12-01 00:00:00
abstract::The biochemical basis for the acquired or natural resistance of various gram-positive organisms to glycopeptides was studied by high-pressure liquid chromatographic analysis of their peptidoglycan UDP-MurNAc-peptide precursors. In all cases, resistance was correlated with partial or complete replacement of the C-termi...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/jb.176.8.2398-2405.1994
更新日期:1994-04-01 00:00:00
abstract::Integrons facilitate the evolution of complex phenotypes by physical and transcriptional linkage of genes. They can be categorized as chromosomal integrons (CIs) or mobile resistance integrons (MRIs). The significance of MRIs for the problem of multiple antibiotic resistance is well established. CIs are more widesprea...
journal_title:Journal of bacteriology
pub_type: 杂志文章
doi:10.1128/JB.00229-08
更新日期:2008-07-01 00:00:00