Abstract:
:By means of an accurate immunoenzymatic assay, the prevalence was studied of antibodies to hepatitis C virus (HCV) in three different populations: 74 patients affected with hepatocellular carcinoma (HCC) on preexisting cirrhosis, 82 patients with liver cirrhosis but with no apparent neoplasm, and 70 control subjects, hospitalized for various conditions, of internal medicine or geriatric interest. 70.2% of HCC patients exhibited anti-HBC antibodies, versus 47.5% of cirrhotic subjects with no tumor and 7.1% of controls. Such results suggest the possible role of HCV in the etiopathogenesis of HCC, and its possible synergy with other agents-e.g., hepatitis B virus, alcohol--in causing chronically injured hepatocytes to become neoplastic.
journal_name
Ups J Med Scijournal_title
Upsala journal of medical sciencesauthors
Porta C,Moroni M,Nastasi G,Ricci G,Casagranda Idoi
10.3109/03009739209179300keywords:
subject
Has Abstractpub_date
1992-01-01 00:00:00pages
261-6issue
3eissn
0300-9734issn
2000-1967journal_volume
97pub_type
杂志文章abstract::The diagnostic distribution and the relation between diagnosis and symptoms, symptom duration, tumour site, tumour size and breast size were studied in 1 244 women with breast symptoms examined at a special breast tumour clinic. 9% of the women had cancer, 62% fibroadenosis and 6% fibroadenoma. In 18% no breast diseas...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737609179022
更新日期:1976-01-01 00:00:00
abstract::Introduction: Carotid endarterectomy (CEA) is a surgical procedure used in the prevention of ischemic stroke. However, this procedure can cause complications of ischemia-reperfusion injury to the brain. Clusterin (CLU) is a cytoprotective chaperone protein that is released from neurons in response to various neurologi...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.1080/03009734.2019.1646359
更新日期:2019-08-01 00:00:00
abstract::Although AL amyloidosis usually is a systemic disease, strictly localized AL deposits are not exceptionally rare. Such case reports form a considerable body of published articles. Although both AL amyloidosis types are formed from an N-terminal segment of a monoclonal immunoglobulin light chain, a typical localized AL...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/03009734.2012.654861
更新日期:2012-05-01 00:00:00
abstract::Early discharge, defined as hospital leave 24-48 hours after birth, was introduced at Falun Hospital in 1984. 164 women interested in participating in an evaluative study of the program were randomly allocated in late pregnancy to an Experimental group (EG) offered early discharge, and a Control group (CG) offered the...
journal_title:Upsala journal of medical sciences
pub_type: 临床试验,杂志文章,随机对照试验,评审
doi:10.3109/03009738709178701
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Non-contrast computed tomography (NCT) has become an important diagnostic tool in acute abdominal pain, but the drawback is the increased radiation dose compared to abdominal plain film (APF). PURPOSE:To evaluate whether NCT, including low-dose computed tomography (LDCT, using 50 mAs), provides more diagnos...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009730903294871
更新日期:2010-05-01 00:00:00
abstract::Pain is one of the most feared problems for adolescents with cancer. Pain produces stress with negative physiological and psychological effects. Therefore, effective pain management during cancer treatment may influence the outcome. This study investigates variations in pain and quality of life during treatment in ado...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-020
更新日期:2006-01-01 00:00:00
abstract::Abstract Pyogenic spondylitis is a common infectious disease caused by various microorganisms. It is difficult to predict the infecting microorganism at the time of initiation of treatment. Pneumonia is generally clarified into community or hospital-acquired types based on where the infection was acquired, and the i...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.687406
更新日期:2012-11-01 00:00:00
abstract::Sertoli-Leydig cell tumours are rare sex stromal tumours with an incidence of < 0.5% of all ovarian tumours. Most frequently this tumour occurs in young women with a history of amenorrhoea, hirsutism and lowered pitch. Here, we report on a woman with IRS, postmenopausal virilization and increased testosterone levels d...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-068
更新日期:2005-01-01 00:00:00
abstract::The vertebral end-plates and the epiphyses from the lumbar region of the spine in juvenile pigs were studied. Cell density of the hyaline cartilage of the vertebral bodies was measured as well as cartilage thickness. The relative bone content in the region of the nucleus pulposus was calculated. A certain negative int...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738509178481
更新日期:1985-01-01 00:00:00
abstract::A material comprising all children in Sweden with acute lymphoblastic leukemia diagnosed in the years 1973-80 was analysed statistically. The total number of children was 505. Studies were made of 38 different variables, using frequency tables, cross tables, life table studies (1) and linear regression analysis accord...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738209178424
更新日期:1982-01-01 00:00:00
abstract::Different pharmacokinetic models for target controlled infusion (TCI) of propofol are available in the recently launched open TCI systems. There is also a compelling choice to work with either plasma- or effect-site targets. Knowledge about the clinical consequences of different alternatives is of importance. We aimed...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-222
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:It has recently been reported that patient selection has a strong impact on the agreement between glomerular filtration rate (GFR) estimates from serum cystatin C and creatinine. The aim of our study was to evaluate the effect of creatinine production rate (CPR) on this subject. MATERIAL AND METHODS:GFR was...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.696154
更新日期:2012-11-01 00:00:00
abstract::SAPHO syndrome is a group of bone and joint abnormalities associated with skin lesions. A 29-year-old male presented with severe acne on his trunk and anterior chest wall, right knee and foot pain. Radiographs and magnetic resonance images showed hyperostosis in the sternocostoclavicular region, sclerosis of one-third...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-045
更新日期:2006-01-01 00:00:00
abstract::Radical surgery for renal cancer with invasion of the inferior vena cava can improve the patient's quality of life and, in some cases, offer longer survival or even cure. With a carefully planned surgical approach it is possible to remove renal tumours with thrombotic extension to the most proximal part of the inferio...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738509178646
更新日期:1985-01-01 00:00:00
abstract::Transforming growth factor-β (TGF-β) elicits both tumor-suppressive and tumor-promoting functions during cancer progression. Here, we describe the tumor-promoting functions of TGF-β and how these functions play a role in cancer progression. Normal epithelial cells undergo epithelial-mesenchymal transition (EMT) throug...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,评审
doi:10.3109/03009734.2011.638729
更新日期:2012-05-01 00:00:00
abstract:AIM:The purpose was to assess the direct costs of screening for high blood pressure and blood glucose in dental care and of follow-up in primary health care and, based on these data, arrive at a prediction function. Study population. All subjects coming for routine check-ups at three dental health clinics were invited ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章,多中心研究
doi:10.3109/03009734.2013.818599
更新日期:2013-11-01 00:00:00
abstract::An investigation was made of 150 women who were diagnosed at the Department of Obstetrics and Gynaecology, University Hospital, Uppsala in 1964-68 as having toxaemia of pregnancy. Eleven had eclampsia and the remainder pre-eclampsia. Toxaemia occurred in 0.88% (average) of all parturients during the study period. Some...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009737809179108
更新日期:1978-01-01 00:00:00
abstract::Fifty-one healthy men, 18 - 19 years of age, with "organic" T wave aberrations (group T) were compared to 112 controls of the same age with normal electrocardiograms (Group A + B). Group T had increased heart rate and higher systolic and diastolic blood pressures. Their lower physical work capacity could be "explained...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738009179186
更新日期:1980-01-01 00:00:00
abstract::Gastrointestinal transit was measured in non-obese diabetic (NOD) mice, as an animal model of human diabetes type 1, and in obese diabetic mice, as an animal model of human diabetes type 2. The endocrine cells known to correlate to gastrointestinal transit, namely secretin, serotonin, Peptide YY (PYY) and enteroglucag...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-139
更新日期:2002-01-01 00:00:00
abstract::Cytosolic carbonic anhydrases CAI, CAII, and CAIII from liver, and CAII, and CAIII from muscle of adult male Sprague-Dawley rats were purified to homogeneity. CAIII from liver and muscle had the same amino acid composition and were immunochemically similar. Their kinetic properties at 0 degrees C were also similar. Km...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-131
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Diabetic patients exhibit platelet hyperreactivity, which renders them resistant to antithrombotic treatments. We aimed to investigate the prevalence and predictors of aspirin resistance in diabetic patients. MATERIAL AND METHODS:A total of 93 diabetic and 37 non-diabetic participants were included into the...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2013.861549
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Atherosclerosis is a generalized disease of the arterial vasculature; among thus it manifests in the descending aorta and the coronary arteries. We tested whether known risk factors, the coronary flow velocity reserve and the grade of aortic atherosclerosis detected by transoesophageal echocardiography in th...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/2000-1967-097
更新日期:2007-01-01 00:00:00
abstract::There has been only one reported case of neuromuscular scoliosis following chronic inflammatory demyelinating polyneuropathy (CIDP). However, no cases of scoliosis that were treated with surgery secondary to CIDP have been previously described. A 16-year-old boy with CIDP was consultant due to the progression of scoli...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2012.757682
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Somatostatin acts through five receptor subtypes (SSTRs 1-5). We aimed to investigate SSTRs mRNA expression and protein distribution in whole rat embryos, with special emphasis on the pancreas. MATERIAL AND METHODS:Rat embryos were collected on embryonal days 10, 11, 12, 14, 15, 17, 19, 21, and at birth. Pr...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2015.1035413
更新日期:2015-01-01 00:00:00
abstract::22 patients with untreated, essential hypertension (diastolic blood-pressure greater than or equal to 140 mmHg) and in most cases also showing neurological symptoms were given a single oral dose of 400 mg labetalol. All patients displayed a gradual decrease of the blood-pressure down to a diastolic pressure about 110 ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738709178680
更新日期:1987-01-01 00:00:00
abstract::Secondary amyloidosis (AA amyloidosis) is a well known cause of nephrotic syndrome and renal failure. Several studies in patients with nephrotic syndrome have suggested a beneficial effect of angiotensin-converting enzyme inhibitors (ACEI). Angiotensin II (ATII) receptor antagonists effect on the long term is not know...
journal_title:Upsala journal of medical sciences
pub_type: 临床试验,杂志文章
doi:10.3109/2000-1967-142
更新日期:2001-01-01 00:00:00
abstract::Since 1975 Sweden has had a patient insurance system to compensate patients for health-related injuries. The system was initially based on a voluntary patient insurance solution, but in 1997 it was replaced by the Patient Insurance Act. The current Act covers both physical and mental injuries. Although about 9,000-10,...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009730903350749
更新日期:2010-05-01 00:00:00
abstract::Rats were starved for 7 days or fed a protein-free or a 25% casein diet for 7 or 14 days. Free and total ribosomes were prepared from the liver. A determination of the ratio of mg RNA of ribosomes to mg DNA of the total homogenate was made. In starved rats, RNA of free and membrane-bound ribosomes decreased to the sam...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009738009179168
更新日期:1980-01-01 00:00:00
abstract::For the corticotropin-releasing-hormone stimulation test the number of samplings and measurements are reduced to two--and the ratio between concentrations at 60 min and 0 min is calculated. The difference between the information given by absolute concentrations and ratio is negligible, but by using ratio, the influenc...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009739309179325
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:Accumulating evidence suggests that enhanced inflammatory responses contribute to the pathogenesis of postoperative cognitive dysfunction (POCD). Blood transfusion can trigger an enhancement of acute inflammatory responses. Therefore, we hypothesized that perioperative blood transfusion is associated with ...
journal_title:Upsala journal of medical sciences
pub_type: 杂志文章
doi:10.3109/03009734.2013.873502
更新日期:2014-08-01 00:00:00