Two-dimensional 1H NMR spectroscopy of normal and pathological human plasma: complete water suppression and further assignment of resonances.

Abstract:

:Two-dimensional J-resolved and correlated 1H NMR spectra with complete water suppression have been obtained to further characterize a metabolic pattern for normal and pathological human plasma samples. 1H COSY spectra have been recorded on plasma from 12 patients with cancer in order to check for the possible presence of fucose. Our results show that there is no evidence for the presence of fucosylated lipids in the plasma of these patients.

journal_name

Biochimie

journal_title

Biochimie

authors

Kriat M,Confort-Gouny S,Vion-Dury J,Viout P,Cozzone PJ

doi

10.1016/0300-9084(92)90075-p

keywords:

subject

Has Abstract

pub_date

1992-09-01 00:00:00

pages

913-8

issue

9-10

eissn

0300-9084

issn

1638-6183

pii

0300-9084(92)90075-P

journal_volume

74

pub_type

杂志文章
  • Targeting human Rad51 by specific DNA aptamers induces inhibition of homologous recombination.

    abstract::Human Rad51 (HsRad51), a key element of the homologous recombination repair pathway, is related to the resistance of cancer cells to chemo- and radio-therapies. This protein is thus a good target for the development of anti-cancer treatments. We have searched for new inhibitors directed against HsRad51 using the Syste...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2010.08.006

    authors: Martinez SF,Renodon-Cornière A,Nomme J,Eveillard D,Fleury F,Takahashi M,Weigel P

    更新日期:2010-12-01 00:00:00

  • Glutamine induces nuclear degradation of the NF-κB p65 subunit in Caco-2/TC7 cells.

    abstract::In the intestine, NF-κB is the main transcription factor involved in the anti-inflammatory effect of glutamine and we previously demonstrated that glutamine via its conversion to glutamate diminished the p65 protein content in Caco-2/TC7 cell nuclei without affecting the stimulating effect of IL-1β on NF-κB [21]. Howe...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2011.11.012

    authors: Lesueur C,Bôle-Feysot C,Bekri S,Husson A,Lavoinne A,Brasse-Lagnel C

    更新日期:2012-03-01 00:00:00

  • Redox regulation of cytochrome P450cam mixed function oxidation by putidaredoxin and camphor ligation.

    abstract::A methylene group of camphor is hydroxylated by a P450 monoxygenase system containing in addition to the cytochrome and flavoprotein dehydrogenase a two-iron, two-sulfur redox protein termed putidaredoxin. The regulatory control of electron transport equilibrium occurs via ligation of substrate and redoxin to the cyto...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/s0300-9084(76)80364-1

    authors: Gunsalus IC,Sligar SG

    更新日期:1976-01-01 00:00:00

  • Protein engineering of ribonucleases.

    abstract::Natural bovine seminal RNase possesses a potent antitumor action. We have mutagenized monomeric bovine pancreatic RNase A, devoid of any cytotoxic action, to insert residues present at corresponding positions in the subunit of dimeric, antitumor, seminal RNase. Like naturally dimeric seminal RNase, the mutant dimeric ...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/s0300-9084(00)88887-2

    authors: Cafaro V,Bracale A,Formiggini F,Notomista E,D'Alessio G,Di Donato A

    更新日期:1998-11-01 00:00:00

  • Cloning and molecular modelling of turkey pancreatic lipase: structural explanation of the increased interaction power with lipidic interface.

    abstract::Starting from total pancreatic mRNAs, turkey pancreatic lipase (TPL) cDNA was synthesized by RT-PCR and cloned into the PGEM-T vector. Amino acid sequence of the TPL is compared to that of human pancreatic lipase (HPL). A 3-D structure model of TPL was built using the 3-D structure of HPL as template, given the high a...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2006.05.022

    authors: Fendri A,Frikha F,Miled N,Gargouri Y

    更新日期:2006-10-01 00:00:00

  • Adiponectin: anti-inflammatory and cardioprotective effects.

    abstract::Adipose tissue is an endocrine organ that plays an essential role in regulating several metabolic functions through the secretion of biological mediators called "adipokines". Dysregulation of adipokines plays a crucial role in obesity-related diseases. Adiponectin (APN) is the most abundant adipokine accounting for th...

    journal_title:Biochimie

    pub_type: 杂志文章,评审

    doi:10.1016/j.biochi.2012.06.030

    authors: Villarreal-Molina MT,Antuna-Puente B

    更新日期:2012-10-01 00:00:00

  • Selection of RNA aptamers against recombinant transforming growth factor-beta type III receptor displayed on cell surface.

    abstract::In most cases, anti-protein aptamers are selected by systematic evolution of ligands by exponential enrichment (SELEX) using purified recombinant protein targets. Cell surface proteins, however, are not easy targets for SELEX due to the difficulties associated with their purification. Here, we developed a novel SELEX ...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2006.02.004

    authors: Ohuchi SP,Ohtsu T,Nakamura Y

    更新日期:2006-07-01 00:00:00

  • Functional consequences of mutating conserved SF2 helicase motifs in the Type III restriction endonuclease EcoP15I translocase domain.

    abstract::For efficient DNA hydrolysis, Type III restriction endonuclease EcoP15I interacts with two inversely oriented recognition sites in an ATP-dependent process. EcoP15I consists of two methylation (Mod) subunits and a single restriction (Res) subunit yielding a multifunctional enzyme complex able to methylate or to hydrol...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2012.11.014

    authors: Mackeldanz P,Alves J,Möncke-Buchner E,Wyszomirski KH,Krüger DH,Reuter M

    更新日期:2013-04-01 00:00:00

  • Three-dimensional structure and antigen binding specificity of antibodies.

    abstract::A number of specific Fab and Fv fragments and their complexes with antigens (avian lysozymes), haptens, and anti-idiotopic Fabs have been studied by immunochemical and crystallographic techniques. Antigen and antibody interact through closely complementary contacting surfaces, without major conformational changes. An ...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/0300-9084(90)90114-v

    authors: Tello D,Spinelli S,Souchon H,Saul FA,Riottot MM,Mariuzza RA,Lascombe MB,Houdusse A,Eiselé JL,Fischmann T

    更新日期:1990-08-01 00:00:00

  • Some novel transcription attenuation mechanisms used by bacteria.

    abstract::A variety of transcription attenuation mechanisms are used by bacteria to regulate gene and operon expression. This review summarizes previous and current studies designed to elucidate the features of the specific attenuation mechanisms that regulate expression of the tryptophanase (tna) operon of Escherichia coli and...

    journal_title:Biochimie

    pub_type: 杂志文章,评审

    doi:10.1016/s0300-9084(97)86725-9

    authors: Yanofsky C,Konan KV,Sarsero JP

    更新日期:1996-01-01 00:00:00

  • c-Jun transcriptionally regulates alpha 1, 2-fucosyltransferase 1 (FUT1) in ovarian cancer.

    abstract::Alpha 1, 2-fucosyltransferase (FUT 1/2) is a rate-limiting enzyme that catalyzes the synthesis of Lewis y, a cell membrane-associated carbohydrate antigen. In human ovarian cancer, the upregulated expression of FUT1 and Lewis y is associated with advanced pathological stages and involved in cell proliferation, migrati...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2014.09.015

    authors: Gao N,Liu J,Liu D,Hao Y,Yan L,Ma Y,Zhuang H,Hu Z,Gao J,Yang Z,Shi H,Lin B

    更新日期:2014-12-01 00:00:00

  • Characterization and primary structure of proteins L28, L33 and L34 from Bacillus stearothermophilus ribosomes.

    abstract::The complete amino acid sequences of 3 proteins from the 50S subunit of Bacillus stearothermophilus ribosomes were determined by N-terminal sequence analysis and by sequencing of overlapping fragments obtained from enzymatic digestions and chemical cleavages. The proteins BstL28, BstL33 and BstL34, named according to ...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/0300-9084(91)90126-l

    authors: Kruft V,Kapp U,Wittmann-Liebold B

    更新日期:1991-07-01 00:00:00

  • Proteases and their inhibitors: today and tomorrow.

    abstract::A major incentive in inhibitor research is that control of limited proteolysis constitutes a valuable pharmacological tool. Protease inhibitors have proved to be successful in influencing pathogenesis in many experimental models but a breakthrough to use in human therapy has mainly been restricted to aprotinin and ang...

    journal_title:Biochimie

    pub_type: 杂志文章,评审

    doi:10.1016/0300-9084(91)90084-e

    authors: Scharpe S,De Meester I,Hendriks D,Vanhoof G,van Sande M,Vriend G

    更新日期:1991-01-01 00:00:00

  • Characterization of HU-like protein from Bifidobacterium longum.

    abstract::A HU-like protein (HBl) of Bifidobacterium longum was purified and characterized. HBl is heat-stable and acid-resistant, and has a molecular weight of about 9.1 kDa as estimated by its mobility on electrophoresis. HBl is intermediate in basicity (pI 9.8) between the HU-1 and HU-2 proteins of Escherichia coli, and is d...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/0300-9084(90)90074-q

    authors: Goshima N,Kano Y,Imamoto F

    更新日期:1990-04-01 00:00:00

  • Oxidative phosphorylation in intact chl-r mutants of Escherichia coli K 12.

    abstract::The efficiency of oxidative phosphorylation was estimated in intact resting cells of Escherichia coli K 12, strain PA 601 (chl-s) and its chl-r mutants, all of them grown anaerobically in the presence of nitrate. The oxidation of endogenous NADH in intact chl-s cells was accompanied by the formation of ATP whatever th...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/s0300-9084(77)80316-7

    authors: Giordano G,Rivière C,Azoulay E

    更新日期:1977-01-01 00:00:00

  • Membrane type-matrix metalloproteinases and tumor progression.

    abstract::Matrix metalloproteinases (MMPs) are a family of zinc endopeptidases that process growth factors, growth factor binding proteins, cell surface proteins, degrade extracellular matrix (ECM) components and thereby play a central role in tissue remodeling and tumor progression. Membrane-type matrix metalloproteinases (MT-...

    journal_title:Biochimie

    pub_type: 杂志文章,评审

    doi:10.1016/j.biochi.2004.07.012

    authors: Sounni NE,Noel A

    更新日期:2005-03-01 00:00:00

  • A review of nutritional effects on fat composition of animal products with special emphasis on n-3 polyunsaturated fatty acids.

    abstract::The fatty acid composition of animal products (eggs, milk and meat) is the reflect of both the tissue fatty acid biosynthesis and the fatty acid composition of ingested lipids. This relationship is stronger in monogastrics (pigs, poultry and rabbits) than in ruminants, where dietary fatty acids are hydrogenated in the...

    journal_title:Biochimie

    pub_type: 杂志文章,评审

    doi:10.1016/j.biochi.2010.02.027

    authors: Kouba M,Mourot J

    更新日期:2011-01-01 00:00:00

  • Aptamers against extracellular targets for in vivo applications.

    abstract::Oligonucleotides are multifunctional molecules which can interfere with gene expression by different mechanism such as antisense, RNA interference, ribozymes, etc. For most in vivo diagnostic and therapeutic applications, oligonucleotides need to be delivered to the intracellular compartment of a specific organ, a dif...

    journal_title:Biochimie

    pub_type: 杂志文章,评审

    doi:10.1016/j.biochi.2005.04.013

    authors: Pestourie C,Tavitian B,Duconge F

    更新日期:2005-09-01 00:00:00

  • Inactivation of proteases and esterases by halomethylated derivatives of dihydrocoumarins.

    abstract::A series of halomethylated derivatives of dihydrocoumarins has been found to inhibit irreversibly proteases and esterases. alpha-Chymotrypsin, subtilish, elastase are rapidly inactivated in the presence of these compounds, while trypsin, kallicrein, papain are inhibited more slowly. Esterases like acetylcholinesterase...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/s0300-9084(77)80140-5

    authors: Béchet JJ,Dupaix A,Roucous C,Bonamy AM

    更新日期:1977-01-01 00:00:00

  • Reciprocal effects of 2-fluoro-2-deoxy-D-glucose and glucose on their metabolism in Saccharomyces cerevisiae studied by multi-nuclear NMR spectroscopy.

    abstract::The effects of various concentrations of 2-fluoro-2-deoxy-D-glucose (FDG) on the aerobic metabolism of glucose and the reciprocal effect of glucose on the metabolism of FDG in glucose-grown repressed Saccharomyces cerevisiae cells were studied at 30 degrees C in a standard pyrophosphate medium containing 5 x 10(7) cel...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/0300-9084(96)88129-6

    authors: Tran-Dinh S,Courtois A,Wietzerbin J,Bouet F,Herve M

    更新日期:1995-01-01 00:00:00

  • Studies on the distribution of ribosomal proteins in mammalian ribosomal subunits.

    abstract::Murine L5178Y cell ribosomes were dissociated into subunits either with potassium chloride in the presence of puromycin or with the chelating agent EDTA. The proteins of ribosomal subunits obtained by these different methods were compared by means of bidimensional polyacrylamide gel electrophoresis. KCl-derived 60S an...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/s0300-9084(80)80225-2

    authors: Longuet M,Auger-Buendia MA,Tavitian A

    更新日期:1979-01-01 00:00:00

  • GKN1 expression in gastric cancer cells is negatively regulated by miR-544a.

    abstract::Gastrokine1 (GKN1), important for maintaining the physiological function of the gastric mucosa, is highly expressed in the stomach of healthy individuals but is down-regulated or absent in gastric tumor tissues and derived cell lines. The mechanisms underlying GKN1 gene inactivation are still unknown. We previously sh...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2019.09.005

    authors: Stella di Stadio C,Faraonio R,Federico A,Altieri F,Rippa E,Arcari P

    更新日期:2019-12-01 00:00:00

  • Aldehyde dehydrogenase and HSP90 co-localize in human glioblastoma biopsy cells.

    abstract::The concept of a stem cell subpopulation as understood from normal epithelial tissue or bone marrow function has been extended to our understanding of cancer tissue and is now the target of treatment efforts specifically directed to this subpopulation. In glioblastoma, as well as in other cancers, increased expression...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2012.11.007

    authors: Rappa F,Cappello F,Halatsch ME,Scheuerle A,Kast RE

    更新日期:2013-04-01 00:00:00

  • Fate of mRNA extremities generated by intrinsic termination: detailed analysis of reactions catalyzed by ribonuclease II and poly(A) polymerase.

    abstract::In all living cells 3' ends of RNA are posttranscriptionally elongated or shortened by nucleotidyl transferases and ribonucleases. The detailed analysis of the rpsO mRNA of Escherichia coli presented here demonstrates that transcription terminates in vivo at two sites located seven and eight nucleotides downstream fro...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2005.02.012

    authors: Folichon M,Marujo PE,Arluison V,Le Derout J,Pellegrini O,Hajnsdorf E,Régnier P

    更新日期:2005-09-01 00:00:00

  • New insights into the formation of HIV-1 reverse transcription initiation complex.

    abstract::HIV-1 reverse transcriptase uses the host tRNA3(Lys) as a primer for the synthesis of the minus DNA strand. The first event in viral replication is thus the annealing of tRNA to the primer binding site (PBS) in the 5' UTR of the viral RNA. This event requires a major RNA rearrangement which is chaperoned by the viral ...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2007.01.016

    authors: Barraud P,Gaudin C,Dardel F,Tisné C

    更新日期:2007-10-01 00:00:00

  • Polyamine acetylation and substrate-induced oligomeric states in histone acetyltransferase of multiple drug resistant Acinetobacter baumannii.

    abstract::Histone acetyltransferase (Hpa2) is an unusual acetyltransferase, with a wide range of substrates; including histones, polyamines and aminoglycosides antibiotic. Hpa2 belongs to GNAT superfamily and GNATs are well known for the formation of homo-oligomers. However, the reason behind their oligomerization remained unex...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/j.biochi.2019.11.015

    authors: Tomar JS,Hosur RV

    更新日期:2020-01-01 00:00:00

  • [Purification and characterization of an extracellular protease from Staphylococcus aureus inhibited by EDTA].

    abstract::A neutral protease, produced by Staphylococcus aureus, strain V8, was purified by precipitation with ammonium sulfate and acetone, and by chromatography on D.E.A.E.-cellulose. The purified protein is homogeneous by acrylamide gel electrophoresis. The molecular weight of the enzyme is estimated to be 28.000 daltons by ...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:10.1016/s0300-9084(76)80310-0

    authors: Saheb SA

    更新日期:1976-01-01 00:00:00

  • [Monkey liver microsomal glucose-6-phosphatase].

    abstract::Kinetic studies indicate that glucose-6-phosphatase is a multifunctional enzyme. a) Phosphohydrolase activities. The mannose-6-phosphatase activity is low (Km = 8 mM, VM = 90 nmoles. min-1mg-1). The enzyme shows a strong affinity for glucose-6-phosphate (Km = 2.5 mM, VM = 220 nmoles.min-1mg-1). beta-glycerophosphate (...

    journal_title:Biochimie

    pub_type: 杂志文章

    doi:

    authors: Benedetto JP,Martel MB,Got R

    更新日期:1979-01-01 00:00:00

  • Therapeutic potential of Mediator complex subunits in metabolic diseases.

    abstract::The multisubunit Mediator is an evolutionary conserved transcriptional coregulatory complex in eukaryotes. It is needed for the transcriptional regulation of gene expression in general as well as in a gene specific manner. Mediator complex subunits interact with different transcription factors as well as components of...

    journal_title:Biochimie

    pub_type: 杂志文章,评审

    doi:10.1016/j.biochi.2017.10.012

    authors: Ranjan A,Ansari SA

    更新日期:2018-01-01 00:00:00

  • Involvement of plasma membrane proteins in plant defense responses. Analysis of the cryptogein signal transduction in tobacco.

    abstract::Cryptogein, a 98 amino acid protein secreted by the fungus Phytophthora cryptogea, induces a hypersensitive response and systemic acquired resistance in tobacco plants (Nicotiana tabacum var Xanthi). The mode of action of cryptogein has been studied using tobacco cell suspensions. The recognition of this elicitor by a...

    journal_title:Biochimie

    pub_type: 杂志文章,评审

    doi:10.1016/s0300-9084(99)80123-0

    authors: Lebrun-Garcia A,Bourque S,Binet MN,Ouaked F,Wendehenne D,Chiltz A,Schäffner A,Pugin A

    更新日期:1999-06-01 00:00:00