[B-cell depletion in the treatment of rheumatoid arthritis].

Abstract:

:New strategies including the blockade of TNFalpha showed excellent therapeutic effects even in so far refractory rheumatic diseases. Moreover, these approaches provided us with important informations about the pathogenic role of the mediators involved and distinct autoimmune cellular subsets. Here, we discuss recent data of a temporary B cell depletion using a monoclonal anti-CD20 antibody in the therapeutic arsenal of rheumatoid arthritis.

journal_name

Z Rheumatol

authors

Feist E,Burmester GR,Dörner T

doi

10.1007/s00393-003-0539-2

keywords:

subject

Has Abstract

pub_date

2003-08-01 00:00:00

pages

361-6

issue

4

eissn

0340-1855

issn

1435-1250

journal_volume

62

pub_type

杂志文章,评审
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  • [TNF alpha-antagonists in collagen vascular disease].

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    doi:10.1007/s00393-003-0530-y

    authors: Manger K,Manger B

    更新日期:2003-06-01 00:00:00

  • [Health-related quality of life (HRQoL) in rheumatoid arthritis].

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    pub_type: 杂志文章,评审

    doi:10.1007/s00393-009-0573-9

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  • The influence of heat and cold on the pain threshold in rheumatoid arthritis.

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    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Curković B,Vitulić V,Babić-Naglić D,Dürrigl T

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    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:

    authors: Tohmé JF,Seibel MJ,Silverberg SJ,Robins SP,Bilezikian JP

    更新日期:1991-05-01 00:00:00

  • [Inflammation-related cardiovascular morbidity : Pathophysiology and therapy].

    abstract::Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are associated with increased mortality, largely as a consequence of cardiovascular (CV) disease. Studies found relative risk ratios of 2 for myocardial infarction in RA and up to 7 for myocardial infarction in SLE patients.Beyond the traditional CV risk...

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    doi:10.1007/s00393-009-0585-5

    authors: Fischer-Betz R,Halle M,Schneider M

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  • [Recommendations of the German Society for Rheumatology for management of patients with inflammatory rheumatic diseases in the context of the SARS-CoV-2/COVID-19 pandemic - Update July 2020].

    abstract::A few days after the SARS-CoV-2 infection was declared a pandemic, the German Society for Rheumatology (DGRh) compiled first recommendations for the care of patients with inflammatory rheumatic diseases (IRD). These first recommendations were based on an expert consensus and were largely non-evidence-based. Now that t...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,实务指引,评审

    doi:10.1007/s00393-020-00851-x

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    更新日期:2020-09-01 00:00:00

  • [Physiotherapy and exercise in osteoporosis and its complications].

    abstract::Osteoporosis is defined by decreased bone strength and increased susceptibility to fracture. Fractures and their consequences are the clinical manifestation of osteoporosis. Acute and chronic pain, functional limitations including permanent impairment and the need for long-term care may be caused by osteoporotic fract...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-009-0445-3

    authors: Preisinger E

    更新日期:2009-09-01 00:00:00

  • [COVID-19: treatment strategies of German-speaking pediatric rheumatologists : Results of an online survey].

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    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-020-00854-8

    authors: Janda A,Schuetz C,Heeg M,Minden K,Hedrich CM,Kallinich T,Hinze C,Schulz A,Speth F

    更新日期:2020-09-01 00:00:00

  • The coexistence of mutilating rheumatoid arthritis, progressive systemic sclerosis and polycythemia vera--a case report.

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    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Hrycaj P,Mackiewicz S

    更新日期:1992-09-01 00:00:00

  • [Histopathogenesis of synovialitis in experimental allergic rabbit arthritis. Comparative studies on rheumatoid synovialitis].

    abstract::The development of synovitis was studied in 64 rabbits with experimentally produced allergic arthritis and in 30 rabbits with experimentally produced non-allergic arthritis. The results are compared with the morphological changes of the synovial membrane in rheumatoid arthritis, especially in early stages, known from ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Püschel W

    更新日期:1982-01-01 00:00:00

  • [Healthcare research in rheumatology. Current state].

    abstract::Health services research in rheumatology investigates the healthcare needs, the quality of care and trends in healthcare for patients with musculoskeletal disorders. Using rheumatoid arthritis (RA) as an example, key results of health services research during the last 25 years are summarized. There are currently appro...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-013-1258-y

    authors: Zink A

    更新日期:2014-03-01 00:00:00

  • [Virus-associated arthritis].

    abstract::From the about 400 virus species known to cause illness in man, only a small but growing list of representatives are able to induce arthritis. Although virus-associated arthritides are mostly of acute and short-living type, some patients develop long-lasting or even chronic joint inflammation. The viral or host factor...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:

    authors: Saal JG

    更新日期:1995-11-01 00:00:00

  • Joint manifestations of Lyme borreliosis in Czechoslovakian patients.

    abstract::Involvement of the musculoskeletal system in 50 Lyme borreliosis patients seen in Czechoslovakia is described. Thirty-three patients reported tick bites or that they had removed a tick, four patients had been bitten by some other insect. Skin reaction following tick bite were found in 29 patients. Neurologic involveme...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Valesová M,Trnavský K

    更新日期:1990-07-01 00:00:00

  • [Novel autoantibodies for the diagnosis of rheumatoid arthritis].

    abstract::The diagnosis of rheumatoid arthritis has been hampered by the lack of a truly disease-specific serologic marker. Thus, despite its moderate specificity rheumatoid factor (RF) is still the only established marker antibody for RA and among the diagnostic criteria of the American College of Rheumatology the only serolog...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-002-0470-y

    authors: Steiner G,Smolen JS

    更新日期:2002-12-01 00:00:00

  • [Evidence-based medicine and applying new therapies in general practice: wish and reality].

    abstract::In the last years some important therapies were introduced in the treatment of rheumatoid arthritis (RA), which represent a significant clinical advance. This concerns the introduction of TNF blockade with etanercept and inflixmab, the combination of DMARDs, leflunomide and the COX-2-specific inhibitors. In the year 2...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s003930170011

    authors: Edelmann E

    更新日期:2001-12-01 00:00:00

  • [Expanded anamnesis and psychodiagnostic classification of psychosomatic rheumatic patients. I: Anamnestic indications of psychosomatic correlations with manifestations of the locomotor system].

    abstract::The author describes the information gained from anamnesis which points to a psychogenetic cause of rheumatic complaints. These symptoms are part of the diagnostically important criteria which must be supplemented still further by means of a personal discussion with the patient. A great deal depends on the skill of th...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Mathies H

    更新日期:1993-07-01 00:00:00

  • [Recommendations for the management of ankylosing spodylitis after ASAS/EULAR. Evaluation in the German language area].

    abstract:AIM:Our aim was to adapt and implement the evidence based recommendations for the management of ankylosing spodylitis (AS) of the "Assessments in AS" (ASAS) International Working Group together with the European League Against Rheumatism (EULAR) within the framework of a competence network (CN) in rheumatology in the G...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-006-0119-3

    authors: Braun J,Zochling J,Märker-Hermann E,Stucki G,Böhm H,Rudwaleit M,Zeidler H,Sieper J

    更新日期:2006-12-01 00:00:00

  • [Immunoablation followed by autologous stem cell transplantation in lupus: a clinical update].

    abstract::Systemic lupus erythematosus (SLE) is a classic systemic autoimmune disease. Standard treatment consists of chronic therapy with antimalarials, glucocorticoids and immunosuppressive/cytotoxic drugs, which is associated with considerable side effects. In contrast, immunoablation of autoreactive immunologic memory follo...

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  • The cytokine-HPA axis feed-back circuit.

    abstract::Due to their anti-inflammatory effects and their capacity to affect the synthesis of most cytokines and the Th1/Th2 balance, endogenous glucocorticoids contribute to control the basal operation of immune cells. Immune processes result in the production of cytokines, such as IL-1, IL-2, IL-6, IL-11, IL-12, TNF-alpha, a...

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    doi:10.1007/s003930070014

    authors: Besedovsky HO,del Rey A

    更新日期:2000-01-01 00:00:00

  • [Medical treatment of rheumatoid arthritis in 2014 : Current data from the German Collaborative Arthritis Centers].

    abstract:BACKGROUND:Since the introduction of biologic treatment in rheumatoid arthritis (RA), disease activity and treatment modalities have changed substantially. The current provision and developments in recent years are analyzed with annual data from the National Database of the Collaborative Arthritis Centers in Germany. ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00393-016-0156-5

    authors: Albrecht K,Huscher D,Eidner T,Kleinert S,Späthling-Mestekemper S,Bischoff S,Zink A

    更新日期:2017-02-01 00:00:00

  • Interleukin-2 activated cells from peripheral blood of patients with systemic lupus erythematosus.

    abstract::The effect of recombinant interleukin-2 (IL-2) on proliferative and cytotoxic response of peripheral blood mononuclear cells (PBMC) was investigated in a group of 21 patients with systemic lupus erythematosus (SLE). There was a significant decrease in thymidine uptake of peripheral blood mononuclear cells when compare...

    journal_title:Zeitschrift fur Rheumatologie

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    doi:

    authors: Jira M,Strejcek J,Zavadil Z,Antosova E,Rejholec V

    更新日期:1990-01-01 00:00:00

  • [Ultrasound findings in chondrocalcinosis].

    abstract::The diagnosis of chondrocalcinosis is based on typical radiographic findings and synoviaanalysis. We examined 10 patients with chondrocalcinosis to see whether pathognomonic findings of the disease could also be seen by ultrasound. Ultrasound and x-ray findings were compared. Calcifications of the knee menisci were se...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Kellner H,Zoller W,Herzer P

    更新日期:1990-05-01 00:00:00

  • [Common variable immunodeficiency: a clinical challenge].

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    journal_title:Zeitschrift fur Rheumatologie

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    authors: Warnatz K,Goldacker S

    更新日期:2013-09-01 00:00:00

  • Do adjacent joints compensate for decreased mobility in a cervical spine segment?

    abstract::The data from a combined pathological and kinesiological investigation in autopsy specimens of the cervical spine were used to test whether adjacent motion segments compensate for loss of mobility at a given level. In the segments adjacent to a low-mobile one no evidence was found of compensatory hypermobility, of an ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Eulderink F,ten Have HA

    更新日期:1982-11-01 00:00:00

  • [Systemic sclerosis - diagnosis and classification].

    abstract::Systemic sclerosis (SSc) is a polymorphic and heterogenic systemic disorder with inflammation, fibrosis and vascular damage. Early diagnosis and classification may be difficult if disease expression is oligosymptomatic (undifferentiated), presenting with only Raynaud's phenomenon or limited scleroderma. Scleroderma sp...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-006-0065-0

    authors: Genth E,Krieg T

    更新日期:2006-07-01 00:00:00

  • [Correlations between irrational attitudes and pain quality in patients with chronic polyarthritis].

    abstract::The present study examined relations between irrational attitudes and pain experience in patients with rheumatoid arthritis (RA). 128 patients with definite RA from a rheumatic treatment center were studied by administration of the Irrational Attitudes Questionnaire (15) and a revised form of the Multidimensional Pain...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Klages U

    更新日期:1990-05-01 00:00:00

  • [Cytogenetic studies of human lymphocytes under the influence of oxicams].

    abstract::The influence of the oxicams, a special group of non-steroidal anti-inflammatory drugs, to the sister chromatid exchange (SCE) was determined on human lymphocytes in vitro and in vivo. The analysis of SCE is a sensitive parameter indicating chromosomal damage. The cytogenetic examinations of Lornoxicam, Tenoxicam, and...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Kullich W,Hermann J,Klein G

    更新日期:1990-03-01 00:00:00

  • An overwhelming pulmonary fungus ball in a systemic lupus erythematosus patient.

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    pub_type: 杂志文章

    doi:10.1007/s00393-003-0492-0

    authors: Kocakoc E,Ozgocmen S,Kiris A,Ozcakar L,Boztosun Y,Yildirim N

    更新日期:2003-12-01 00:00:00