Abstract:
PURPOSE:The graphical approach is widely used for the pixelwise determination of local metabolic rate of glucose from dynamic positron emission tomography (PET) data. In its conventional implementation, measured integrals over time frames are used to approximate instantaneous tracer concentrations at midframe times ("midframe approach"). This is justified in case of high temporal resolution of the PET measurement; that is, if scan protocols with a large number of short frames are used. This requires fast data handling and large amounts of memory. Cardiac gating and three-dimensional (3D) acquisition of dynamic studies is hardly possible with this approach. Therefore, a new variant of the graphical method is proposed which can be used with a very low number of rather long frames. METHODS:An operational equation of the graphical method was derived which uses measured time integrals only and, thus, avoids the systematic errors of the midframe approximation. This "integral approach" was evaluated in computer simulations based on experimental data. RESULTS:The integral approach enables the use of protocols with 3 frames only without compromising accuracy of the derived metabolic rates whereas the midframe approach leads to bias of about 10% to 20% for these protocols. Furthermore, test-retest stability can significantly be improved when using the integral approach. CONCLUSION:The integral approach to the graphical evaluation of dynamic PET data yields accurate and precise results using scan protocols with down to only 3 frames. This can be relevant to gating and/or 3D acquisition of dynamic studies. The integral approach is applied most naturally whenever the input function is derived from the dynamic PET data.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Buchert R,van den Hoff J,Mester Jdoi
10.1097/00004728-200307000-00026keywords:
subject
Has Abstractpub_date
2003-07-01 00:00:00pages
597-605issue
4eissn
0363-8715issn
1532-3145pii
00004728-200307000-00026journal_volume
27pub_type
杂志文章abstract:OBJECTIVE:This study aimed to observe the value of computed tomography (CT) spectral imaging parameters in the diagnosis of solitary pulmonary nodules, during the contrast-enhanced early phase and late phase. MATERIALS AND METHODS:This study was approved by the institutional review board and written informed consent w...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000469
更新日期:2016-11-01 00:00:00
abstract::Construction of a new ultrafast scanner system suitable for dynamic computed tomography is now under consideration, with development soon to begin. This system will be characterized by an electronically controlled X-ray generator with wide angle double diffraction, which will permit transverse axial images to be taken...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197710000-00017
更新日期:1977-10-01 00:00:00
abstract:OBJECTIVE:A method for identification and quantitative evaluation of task-specific changes of the regional cerebral blood flow (rCBF) measured with PET in activation studies of individual subjects is presented. The method is based on the statistical distributions of the quantitative and spatial information of regions o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199307000-00002
更新日期:1993-07-01 00:00:00
abstract:PURPOSE:To determine the feasibility of diffusion-weighted magnetic resonance (MR) imaging (DWI) of uterine cervical cancer and to investigate whether the apparent diffusion coefficient (ADC) values of cervical cancer differ from those of normal cervix and whether they could indicate the histologic type and the patholo...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31819e93af
更新日期:2009-11-01 00:00:00
abstract:OBJECTIVES:To characterize diffusion tensor imaging (DTI) tensor eigenvalues (λ1, λ2, λ3), fractional anisotropy, mean diffusivity, and radial diffusivity in healthy lumbar musculature. METHODS:Seventeen healthy subjects (10 men, 7 women; mean age, 28 ± 7 years) were scanned using a 3.0-T magnetic resonance imaging. A...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3182772d66
更新日期:2013-01-01 00:00:00
abstract::A case of isolated spinal cord hemangioblastoma with associated extensive syringohydromyelia, which was evaluated by myelography, postmyelographic CT, magnetic resonance (MR), and angiography is presented. The specific preoperative and postoperative advantages of MR are given as well as a brief review of the literatur...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198805010-00028
更新日期:1988-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to describe the characteristics of lung cancers in patients with tuberculous fibrothorax or empyema. METHODS:We retrospectively evaluated 138 consecutive patients with a diagnosis of lung cancer combined with fibrothorax (n = 127) or empyema (n = 11) from January 2005 to May 2015. A...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000608
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND AIMS:To prospectively determine the accuracy of liver fat quantification with magnetic resonance imaging (MRI). PATIENTS AND METHODS:The population consisted of 40 patients (mean age, 52.5 years; range, 23-78 years). The same day, all patients underwent MRI and ultrasonography-guided liver biopsy. The h...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318199d883
更新日期:2009-09-01 00:00:00
abstract::High-resolution contrast-enhanced dynamic MRI of the uterus can be performed with the combination of a phased-array multicoil and fast GE techniques. This technique can improve the ability to visualize normal anatomy of the uterus and periuterine tissues, including vascular structures and pelvic ligaments, and to dete...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199809000-00015
更新日期:1998-09-01 00:00:00
abstract::Magnetic resonance imaging of the larynx was performed on 15 volunteers. Searching for optimal images in the sagittal, frontal, and transverse planes, we compared images made with a special surface coil and the standard head coil, images with different slice thicknesses, images with different repetition times (TR) and...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198509000-00015
更新日期:1985-09-01 00:00:00
abstract::Subcutaneous fat provides excellent contrast for water density tissue. Five patients with subcutaneous metastases visualized on computed tomography (CT) scans are presented. In some cases, CT proved to be the optimal diagnostic modality for visualizing these lesions and documenting their response to therapy. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197807000-00005
更新日期:1978-07-01 00:00:00
abstract:OBJECTIVE:Fibrothecomas of the ovary are mesenchymal tumors representing 4-5% of all ovarian neoplasms. The purpose of this study is to describe a large series of CT findings in this type of tumor. MATERIALS AND METHODS:We reviewed retrospectively the CT examinations in 25 unilateral cases confirmed by surgery and pat...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199309000-00017
更新日期:1993-09-01 00:00:00
abstract::We describe a new multistep procedure for CT fluoroscopy-guided core biopsy, which allows confirmation of the biopsy-sampling trough and the final needle tip position prior to sampling. Twelve lesions measuring < or =2 cm or in close proximity to vital structures were biopsied using commercially available biopsy syste...
journal_title:Journal of computer assisted tomography
pub_type: 临床试验,杂志文章
doi:10.1097/00004728-200003000-00015
更新日期:2000-03-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the exclusive performance of quality-assured high-resolution breast magnetic resonance imaging (MRI) for early detection of breast cancer in a population of asymptomatic women. MATERIALS AND METHODS:A total of 1189 MRI examinations performed in 789 asymptomatic women (mean...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000650
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the accuracy of dynamic laryngeal computed tomography (DLCT) for the detection of vocal cord mobility in larynx cancer. METHODS:Vocal cord mobility of 44 patients (36 men; age range, 49-81 years) with larynx cancer was examined; 13 patients were excluded (owing to poor image quality or bilateral ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31825b85ce
更新日期:2012-07-01 00:00:00
abstract::Bullous lung disease is known to be a risk factor for developing a bronchogenic carcinoma. In this article, computed tomography appearances of 20 patients with histologically proven bronchogenic carcinoma were reviewed retrospectively. On the basis of the previous literatures and our findings, the computed tomography ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200605000-00016
更新日期:2006-05-01 00:00:00
abstract::Seven cases of Poland syndrome were investigated with CT and/or MR to assess the extent of the muscle abnormalities of the shoulder girdle. In all cases the absence of the sternocostal head of the pectoralis major was clearly shown, as were any associated abnormalities of the pectoralis minor, serratus anterior, and l...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199205000-00019
更新日期:1992-05-01 00:00:00
abstract::Cystic hygromas most often occur in the neck in children and are benign lesions not associated with cranial nerve palsies. We present two cases in which a facial nerve paralysis was one of the presenting symptoms. The computed tomographic (CT) scans localized the lesions, suggested a diagnosis, and obviated angiograph...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198402000-00021
更新日期:1984-02-01 00:00:00
abstract::We report imaging findings of renal matrix stones in a patient with congenital ureteropelvic junction obstruction associated with urinary tract infection. The stones were composed of a calcified center and a non-calcified peripheral matrix that was slightly high attenuated on CT and nonshadowing on US. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199605000-00015
更新日期:1996-05-01 00:00:00
abstract::An increase in the effective atomic number of blood is among the factors allowing or influencing the visualization of the major cerebral vessels on noncontrast CT. Bromine (atomic number, 50) attenuates 70 keV X-rays significantly and was responsible for a striking enhancement of the major cerebral vessels on the nonc...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198410000-00035
更新日期:1984-10-01 00:00:00
abstract::A new 6 mm collimator for the EMI CT5000/5005 scanner is described. It consists of a narrower tube side and detector side collimator that can be set up in less than 5 min. The applications are primarily for the orbit and parasellar area. Future applications with the aid of new software include coronal reconstruction. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197807000-00029
更新日期:1978-07-01 00:00:00
abstract::Congenital alimentary duplications occur most commonly in relation to the ileum and are rare in the region of the stomach. A case of gastric duplication presenting in an adult and visualized on computed tomography is reported. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198304000-00025
更新日期:1983-04-01 00:00:00
abstract:OBJECTIVE:We compared body coil (BC) MR images and endorectal surface coil (ERC) images with respect to the visualization of the cervix and adjacent tissues and the histopathologic correlations of the imaging findings. MATERIALS AND METHODS:Twenty-one patients with cervical carcinoma underwent MRI using both coils for...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVES:This article describes magnetic resonance imaging (MRI) findings in 3 cases of atypical polypoid adenomyoma (APAM). METHODS:Clinical and MRI manifestations of 3 patients with APAM were evaluated. High b value diffusion-weighted and dynamic contrast-enhanced images were performed. The size, shape, site of or...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000169
更新日期:2015-01-01 00:00:00
abstract::The magnetic resonance (MR) cine display of flexion and extension (F/E) manoeuvres in the cervical spine has proved useful in the evaluation of cord compression due to bone and joint instability, spondylosis, and multiple tumours. It has advantages over X-ray F/E and CT myelography in that it is noninvasive and produc...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198811000-00008
更新日期:1988-11-01 00:00:00
abstract::We report the MR features in two patients presenting with symptomatic thecal impingement by posterior epidural cysts linking a bilateral lumbar spondylolysis. Large fluid-filled channels bridging the ruptured partes interarticulares were present in spite of the absence of significant arthritic changes within the adjac...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199907000-00008
更新日期:1999-07-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to compare the image quality of renal arteries and veins with dual-energy spectral computed tomography (CT) imaging in late arterial phase using 270 and 320 mg I/mL of iodixanol and their influence on renal function. METHODS:A total of 1062 patients underwent renal CT angiogra...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000595
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:To analyze and to describe the shape and contraction of the normal right ventricle (RV) as visualized by magnetic resonance imaging (MRI). METHODS:Thirty normal volunteers were imaged using cine MRI in axial, short-axis, and long-axis planes. The shape and contraction of the RV were qualitatively evaluated. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000179596.86221.38
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:Our goal was to assess the utility of different imaging directions in volumetric studies of the heart with MRI, in particular to identify the optimal imaging plane for studies of the right ventricle. METHOD:We examined 12 sets of human four-chamber cadaveric cardiac casts. Gradient echo MRI was performed in fo...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199811000-00012
更新日期:1998-11-01 00:00:00
abstract::Magnetic resonance is recognized as potentially the best imaging procedure for localization in stereotactic neurosurgery. However, special difficulties necessitate specific adaptation to localize targets in the stereotactic frame. We developed a new method for stereotactic localization. The MR studies were performed u...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199103000-00020
更新日期:1991-03-01 00:00:00