A cellular protein specifically binds to the 3'-terminal sequences of hepatitis C virus intermediate negative-strand RNA.

abstract：:The RV lead position, either RVA or RVHS appears to make no difference in the response to CRT but the LV lead placement play a vital role.9,30 The latest activated regions of LV or areas without transmural myocardial scar for an optimal CRT are preferred. Currently, data demonstrate that no significant difference of c...

journal_title：Chinese medical journal

authors： Dong YX,Boodhna J,Yang YZ

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To investigate the effects of the combination of octreotide and aspirin on the growth of gastric cancer. METHODS:Proliferation of gastric cancer cell lines treated with octreotide or aspirin was determined by (3)H-thymidine incorporation. After xenografts of human gastric cancer were implanted orthotopically...

journal_title：Chinese medical journal

authors： Tang C,Wang C,Tang L

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term efficacy and safety of lamivudine therapy for the treatment of chronic hepatitis B and the clinical influence of emergence of tyrosine methionine aspartic acid (YMDD) motif mutation of hepatitis B virus (HBV). METHODS:This multicenter, double-blind, randomized, placebo controlled tr...

journal_title：Chinese medical journal

authors： Yao G,Cui Z,Wang B,Yao J,Zeng M

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:One of the major causes of death in severe acute pancreatitis (SAP) is severe infection owing to bacterial translocation. Some clinical studies suggested that ecoimmunonutrition (EIN) as a new strategy had better treatment effect on SAP patients. But the experiment studies on the precise mechanism of the eff...

journal_title：Chinese medical journal

authors： Xu GF,Lu Z,Gao J,Li ZS,Gong YF

更新日期：2006-04-20 00:00:00

abstract：:A 16-year-old female patient with systemic lupus erythematosus (SLE) presented with abdominal pain and oliguria, after one month of hospital treatment with methylprednisolone and cyclophosphamide. Computed tomography of the abdomen revealed the calcification of bilateral superior segmental ureteral wall. Computed tomo...

journal_title：Chinese medical journal

authors： Jiang DX,Liao Y,Bai YJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcriptional factor that could improve the stimulation of angiogenesis and the metabolic adaptation of tumor cells to hypoxia. A recent study showed that HIF-1alpha could induce colon cancer cells epithelial-mesenchymal transition (EMT). However, no eviden...

journal_title：Chinese medical journal

authors： Luo Y,He DL,Ning L,Shen SL,Li L,Li X

更新日期：2006-05-05 00:00:00

abstract：OBJECTIVE:To evaluate the effect of preoperative transcatheter arterial chemoembolization(TACE) on apoptosis of hepatocellular carcinoma (HCC) cells. METHODS:A total of 136 patients with HCC underwent liver resection. One to five courses of TACE prior to liver resection were performed in 79 patients (TACE group), in w...

journal_title：Chinese medical journal

authors： Xiao E,Li D,Shen S,Zhou S,Tan L,Wang Y,Luo J,Wu Y,Tan C,Liu H,Zhu H

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:In steroid-induced osteonecrosis, hypertrophy and hyperplasia of marrow fat cells and lipid deposition of osteocytes can be found in the femoral head. However, the precise reason is not clear yet. The aim of this study was to observe the effect of dexamethasone (Dex) on differentiation of marrow stromal cell...

journal_title：Chinese medical journal

authors： Yin L,Li YB,Wang YS

更新日期：2006-04-05 00:00:00

abstract：:The radiographic measurement of the prevertebral soft tissue of cervical vertebrae was performed in 87 normal adults. According to the results of the measurement, 10 mm and 20 mm were used as the upper limit normal values of the retropharyngeal and retrotracheal space respectively. We conclude that although the widene...

journal_title：Chinese medical journal

authors： Dai LY,Jia LS

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Our previous studies have shown that both apoptosis and necrosis are involved in hair cell (HC) pathogenesis in aging cochleae. To better understand the biological mechanisms responsible for the regulation of HC death, we examined the activity of succinate dehydrogenase (SDH), a mitochondrial bioenergetic en...

journal_title：Chinese medical journal

authors： Yang WP,Hu BH,Sun JH,Zhai SQ,Henderson D

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Clinical application of autologous fat grafting (AFG) is quickly expanding. Despite the widely acceptance, long-term survival rate (SR) of AFG remains a question not yet solved. Meanwhile, although rare, severe complications related to AFG including vision loss, stroke even death could be seen in the literatu...

journal_title：Chinese medical journal

authors： Yu NZ,Huang JZ,Zhang H,Wang Y,Wang XJ,Zhao R,Bai M,Long X

更新日期：2015-05-05 00:00:00

abstract：BACKGROUND:Chronic hepatic inflammation is characterized by the accumulation of lymphocytes as a consequence of increased recruitment from the blood and retention within the tissue at sites of infection. CXC chemokine ligand 16 (CXCL16) mRNA has been detected in both inflamed and normal liver tissues and is strongly up...

journal_title：Chinese medical journal

authors： Wang P,Kan QC,Yu ZJ,Li L,Pan X

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:There have been no mortality/morbidity endpoint studies with losartan in Chinese heart failure patients. The objective was to evaluate the effects of high-dose vs. low-dose losartan on clinical outcomes in Chinese subjects with heart failure. METHODS:This study was a post hoc analysis of the Heart failure E...

journal_title：Chinese medical journal

authors： Hu DY,Huang J,Cai NS,Zhu WL,Li YS,Massaad R,Hanson ME,Dickstein K

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Retroperitoneal sarcoma is a rare disease with poor prognosis. The aim of this study was to investigate the prognostic factors of the disease. METHODS:Between January 1988 and December 2003, 132 patients with retroperitoneal sarcoma were surgically treated in our hospital, 79 of them were followed up for 1 ...

journal_title：Chinese medical journal

authors： Chen CQ,Yin L,Peng CH,Cai Y,Li YF,Zhao R,Zhou HJ,Li HW

更新日期：2007-06-20 00:00:00

abstract：BACKGROUND:Using tissue Doppler imaging and conventional echocardiographic technique, we examined the cardiac function and synchronicity in individuals with isolated right bundle branch block (RBBB) or left bundle branch block (LBBB) and assessed the relationship between QRS duration and synchronicity. METHODS:Subject...

journal_title：Chinese medical journal

authors： Niu HX,Hua W,Zhang S,Sun X,Wang FZ,Chen KP,Wang H,Chen X

更新日期：2006-05-20 00:00:00

abstract：BACKGROUND:Acute lung injury (ALI) is a serious and common condition for which there are currently no specific strategies for treatment. Recent studies have suggested that bone marrow-derived multipotent mesenchymal stem cells (MSCs) may have therapeutic applications in multiple clinical disorders. We explored the biol...

journal_title：Chinese medical journal

authors： Liang ZX,Sun JP,Wang P,Tian Q,Yang Z,Chen LA

更新日期：2011-09-01 00:00:00

abstract：:Myocardial revascularization by Nd: YAG laser used in rats with myocardial infarction was studied. The left coronary artery was ligated and the laser channels with a diameter of 300 microns were made immediately by 2.5-4.2 W lasersonics YAG unit. After 24 hours, the rats were killed. Evaluation included hemodynamics, ...

journal_title：Chinese medical journal

authors： Guo JX,Pan J,Ma L,Chen MZ,Xu H,Shi AY

更新日期：1993-09-01 00:00:00

abstract：:Plasma levels of tissue plasminogen activator (tPA) antigen, tPA activity and plasminogen activator inhibitor (PAI) activity were determined in 40 cases of acute myocardial infarction (AMI) at the onset and 2-4 weeks after the onset of the disease. 24 healthy subjects served as controls. At the onset of AMI, mean plas...

journal_title：Chinese medical journal

authors： Chen HZ,Jia HY,Song HY,Wang JY

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Recurrence of hepatitis B-related hepatocellular carcinoma (HCC) after curative resection is the leading factor influencing the prognosis of the disease. Therefore, further improvement of long-term survival may depend on the prevention and treatment of the recurrent tumor. The aim of this research was to inv...

journal_title：Chinese medical journal

authors： Yan Q,Ni J,Zhang GL,Yao X,Yuan WB,Zhou L,Zheng SS

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Colloid carcinomas of the pancreas have better prognosis than ordinary ductal adenocarcinoma, and preoperative distinction of colloid carcinoma from other pancreatic tumors is valuable for patient therapeutic planning and prognosis assessment. However, data about CT features of colloid carcinoma are very lim...

journal_title：Chinese medical journal

authors： Ren FY,Shao CW,Zuo CJ,Lu JP

更新日期：2010-05-20 00:00:00

abstract：OBJECTIVES:To analyze the FBN1 mutations in Chinese patients with Marfan syndrome (MFS) and to make a genetic diagnosis based on haplotype linkage analysis for MFS. METHODS:Nine MFS families (17 patients) were analyzed with single strand conformation polymorphism (SSCP) and sequencing. Four primers were designed for t...

journal_title：Chinese medical journal

authors： Wang B,Hu D,Xia J,Li Q,Yang J,Lu G

更新日期：2003-07-01 00:00:00

abstract：:Four calcium channel blockers, i.e. nifedipine, verapamil, cinnarizine and tetrandrine are currently available and used widely in treating cardiovascular diseases. To confirm the effects, if any, of calcium channel blockers on cirrhotic patients with portal hypertension, a study was performed on esophageal variceal pr...

journal_title：Chinese medical journal

authors： Li D,Lu H,Li X,Quan Q,Li X,Lu W

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Artificial joints present certain problems such as osteal absorption and lysis induced by wear debris which leads to loosening of the prosthesis over a period of time. Here we propose a design of an artificial magnetic suspension joint that was prepared by integrating the medical theories of modern material ...

journal_title：Chinese medical journal

authors： Dai M,Nie T

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Donor and recipient risk factors on graft function have been well characterized. The contribution of demographic factors, such as age, gender, and other potential factors of donor and recipient at the time of transplantation on the function of a graft is much less well understood. In this study, we analyzed ...

journal_title：Chinese medical journal

authors： Lin J,Zheng X,Xie ZL,Sun W,Zhang L,Tian Y,Guo YW

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Candidal esophagitis is the primary infection among all digestive tract opportunistic ones in acquired immunodeficiency syndrome (AIDS) cases. X-ray manifestation reports of it are still rare. This study aimed to conduct a retrospective analysis on the X-ray data of 6 AIDS cases complicated with candidal eso...

journal_title：Chinese medical journal

authors： Yang GD,Lu PX,Qin J,Liu ST,Zhan NY

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:The incidence of vancomycin-resistant enterococci (VRE) appeared to be increasing in China, but very few nosocomial outbreaks have been reported. Our hospital had experienced an outbreak of VRE since March 2008 to March 2009. The objective of this study was to analyze the molecular features of the isolates a...

journal_title：Chinese medical journal

authors： Xu HT,Tian R,Chen DK,Xiao F,Nie ZY,Hu YJ,Zhang XZ,Li JM

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVE:To study the histopathological changes of relevant internal organs of Macaca mulatta infected with Plasmodium knowlesi (P. knowlesi). METHODS:Histopathological examination of 3 monkeys who died of P. knowlesi infection, 2 P. knowlesi infected monkeys who died of treatment failure with artesunate suppository ...

journal_title：Chinese medical journal

authors： Chen L,Li G,Lu Y,Luo Z

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:The P53 tumor suppressor gene shows the most frequent genetic alteration in human tumors. Mutation, deletion and rearrangement of P53 gene have been found in several types of neoplasm including osteosarcoma. The present study is to clarify the status of abnormalities of this gene in osteosarcoma in China. MA...

journal_title：Chinese medical journal

authors： Guo W,Wang X,Feng C

更新日期：1996-10-01 00:00:00

abstract：:Preeclampsia is represented by hypertension and proteinuria in pregnancy. It usually occurs after 20 gestational weeks. There are few reports on preeclampsia before 20 gestational weeks. In this case, we report a patient with chronic hypertension superimposed with preeclampsia at 13 gestational weeks. ...

journal_title：Chinese medical journal

authors： Zhu YC,Sun Y,Yang HX

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Severe valgus deformity often has bone defect and laxity of the medial ligamentous, and total knee arthroplasty in severe valgus knee is, in most cases, more challenging for surgeons. The usefulness of a computer assisted navigation system in reestablishing the mechanical axis has been well established. Henc...

journal_title：Chinese medical journal

authors： Shao JJ,Zhang XL,Wang Q,Chen YS,Shen H,Jiang Y

更新日期：2010-10-01 00:00:00