A review of the clinical efficacy and tolerability of almotriptan in acute migraine.

abstract：INTRODUCTION:Glaucoma is the second leading cause of blindness globally, representing a significant public health concern. More than 60 million people are affected by glaucoma worldwide; as this population ages, the number is expected to increase. Glaucoma is a collection of heterogeneous diseases sharing common clinic...

journal_title：Expert opinion on pharmacotherapy

authors： Konstas AG,Quaranta L,Realini T

更新日期：2012-04-01 00:00:00

abstract：INTRODUCTION:Bipolar I disorder (BD I) is complex with a chronic course that significantly impacts a sufferer's quality of life. As of right now, there are many available treatments that aim to rapidly treat manic or depressive episodes and stabilize mood. The purpose of this report is to provide an up-to-date comprehe...

journal_title：Expert opinion on pharmacotherapy

authors： Morsel AM,Morrens M,Sabbe B

更新日期：2018-02-01 00:00:00

abstract：INTRODUCTION:Hairy cell leukemia (HCL) is a B-cell lymphoid malignancy that accounts for approximately 2% of all leukemias. Treatment with purine nucleoside analogs (PNA) results in a high response rate and remains the standard of care. Long term follow-up shows that most patients relapse and require retreatment. Newer...

journal_title：Expert opinion on pharmacotherapy

authors： Ramos Perez J,Ravandi-Kashani F

更新日期：2020-08-01 00:00:00

abstract：:Pancreatic cancer has one of the worst prognosis of any malignant disease. Systemic therapy is often administered because the disease is usually detected at advanced stages. Gemcitabine (Gemzar trade mark, Eli Lilly & Co.) has proven activity in the treatment of pancreatic cancer. Gemcitabine 1000 mg/m(2) was given on...

journal_title：Expert opinion on pharmacotherapy

authors： Karasek P,Skacel T,Kocakova I,Bednarik O,Petruzelka L,Melichar B,Bustova I,Spurny V,Trason T

更新日期：2003-04-01 00:00:00

abstract：:This paper describes the functional roles of the closely related pharmacogenetic and pharmacogenomic sciences in medicine. Firstly, they provide means for a better understanding of the function of drugs, and particularly of the differences of drug action between individuals and also between racially categorised popula...

journal_title：Expert opinion on pharmacotherapy

authors： Kalow W

更新日期：2005-07-01 00:00:00

abstract：:Insulin glulisine (Apidra, Sanofi-Aventis), a new and recently approved rapid-acting insulin analogue, mimics the pharmacokinetic and pharmacodynamic profiles of physiological human insulin, but has a rapid onset, peak effect at 1h, and a shorter duration of action (approximately 4 h). Its rapid-action properties are ...

journal_title：Expert opinion on pharmacotherapy

authors： Garg SK,Ellis SL,Ulrich H

更新日期：2005-04-01 00:00:00

abstract：INTRODUCTION:Our knowledge about lower respiratory tract infections (LRTIs) has improved substantially in the last years, but the management of respiratory infections is still a challenge and we are still far from using precision medicine in their treatment. Areas covered: The approaches developed in recent years to im...

journal_title：Expert opinion on pharmacotherapy

authors： Cazzola M,Rogliani P,Aliberti S,Blasi F,Matera MG

更新日期：2017-07-01 00:00:00

abstract：INTRODUCTION:Increasing population age, obesity and physical inactivity mean that type 2 diabetes mellitus (T2DM) is increasingly common. Current treatments may be limited by adverse events, drug-drug interactions or contraindication/need for dose adjustment in patients with renal impairment. AREAS COVERED:This paper ...

journal_title：Expert opinion on pharmacotherapy

authors： Forst T,Pfützner A

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Diabetic foot ulcers, especially when they become infected, are a leading cause of morbidity and may lead to severe consequences, such as amputation. Optimal treatment of these diabetic foot problems usually requires a multidisciplinary approach, typically including wound debridement, pressure off-loading,...

journal_title：Expert opinion on pharmacotherapy

authors： Abbas M,Uçkay I,Lipsky BA

更新日期：2015-04-01 00:00:00

abstract：:The use of tamoxifen among women with breast cancer or at high risk of the disease has greatly expanded over the past several decades. Tamoxifen has a complex effect on the female reproductive tract and several tamoxifen-associated changes have been described among tamoxifen users. These include endometrial thickening...

journal_title：Expert opinion on pharmacotherapy

authors： Eltabbakh GH,Mount SL

更新日期：2001-09-01 00:00:00

abstract：INTRODUCTION:Treatment of unresectable or metastatic urothelial carcinoma (UC) has historically relied upon platinum-based chemotherapy and, more recently, immune checkpoint inhibitors. When tumors progress despite those therapies, remaining effective options are limited. AREAS COVERED:In this review, the authors revi...

journal_title：Expert opinion on pharmacotherapy

authors： Nauseef JT,Villamar DM,Lebenthal J,Vlachostergios PJ,Tagawa ST

更新日期：2020-06-01 00:00:00

abstract：:In the recent years, advances in the treatment of chronic hepatitis B and C have shown that newer, more expensive therapy may result in higher sustained viral response rates. In light of this, the pertinent question for healthcare decision-makers centres around whether this increase in efficacy 'justifies' the additio...

journal_title：Expert opinion on pharmacotherapy

authors： Younossi ZM,Temple ME,Shermock KM

更新日期：2001-02-01 00:00:00

abstract：:Amyotrophic [corrected] lateral sclerosis (ALS) is a progressive degenerative condition of motor neurons that is ultimately fatal. Even though scientific discovery over the past few decades has led to a greater understanding of the pathogenic mechanisms of ALS, effective pharmacotherapy intended to slow, arrest or rev...

journal_title：Expert opinion on pharmacotherapy

authors： Weiss MD,Weydt P,Carter GT

更新日期：2004-04-01 00:00:00

abstract：INTRODUCTION:Allergic rhinitis (AR) can be challenging to treat. For many patients, current therapies (including multiple therapies) provide insufficient symptom relief. There is, therefore, a clear unmet medical need for a new and more effective AR treatment option. MP29-02 ( Dymista ) is a novel intranasal formulatio...

journal_title：Expert opinion on pharmacotherapy

authors： Bernstein JA

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:Postpartum depression (PPD) is a common and serious illness that affects up to 14% of women in the first month after childbirth. We present an update on the pharmacologic treatment of PPD, although there continues to be a lack of large, randomized controlled trials (RCTs). AREAS COVERED:A review of the li...

journal_title：Expert opinion on pharmacotherapy

authors： Kim DR,Epperson CN,Weiss AR,Wisner KL

更新日期：2014-06-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is a rare disease characterized by the accumulation of clonal dendritic cells in different organs. Most recent findings (e.g., activating BRAF mutations) favor the hypothesis that LCH may represent a neoplasm with varying behavior, but the ultimate pathogenesis remains to be uncover...

journal_title：Expert opinion on pharmacotherapy

authors： Minkov M

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Transurethral resection of bladder tumor (TURBT) is the gold standard initial diagnostic intervention for bladder cancer and provides diagnostic, therapeutic and prognostic benefit in non-muscle-invasive bladder cancer (NMIBC). However, TURBT alone is inadequate for optimal management of NMIBC, as patients...

journal_title：Expert opinion on pharmacotherapy

authors： Patel SG,Cohen A,Weiner AB,Steinberg GD

更新日期：2015-04-01 00:00:00

abstract：:Non-motor symptoms may considerably reduce parkinsonian quality of life, particularly in advanced stages of the disease. Autonomic features, such as seborrhoea, hyperhidrosis, orthostatic hypotension, excessive salivation, bladder dysfunction and GI disturbances, and neuropsychiatric symptoms, such as depression, slee...

journal_title：Expert opinion on pharmacotherapy

authors： Müller T

更新日期：2002-04-01 00:00:00

abstract：:Management of patients undergoing cardiac surgery has evolved in recent years as more is understood about the physiological changes and responses that occur during and after cardiopulmonary bypass (CPB). In particular, our understanding of the mechanisms involved in haemostasis and in the inflammatory response to bypa...

journal_title：Expert opinion on pharmacotherapy

authors： Punjabi PP,Wyse RK,Taylor KM

更新日期：2000-12-01 00:00:00

abstract：INTRODUCTION:Nonadherence is still a major problem in the long-term treatment of schizophrenia. Long-acting injectable or depot atypical antipsychotics are associated with better maintenance. Olanzapine pamoate, available since 2010, is the second depot atypical antipsychotic. AREAS COVERED:This review covers data on ...

journal_title：Expert opinion on pharmacotherapy

authors： Naber D

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:Despite the availability of many antihypreglycemic agents, many patients with type 2 diabetes (T2DM) fail to achieve the glycemic treatment goal, primarily due to progressive beta-cell dysfunction, and increased risk of hypoglycemia. AREAS COVERED:The aim of the present article is to review the efficacy a...

journal_title：Expert opinion on pharmacotherapy

authors： Abdul-Ghani MA,DeFronzo RA

更新日期：2013-08-01 00:00:00

abstract：INTRODUCTION:Hepatocellular carcinoma (HCC) is a frequent and severe complication of cirrhosis. Most HCC patients initially present with or progress to advanced stage disease and require systemic treatment. As hypervascularization is a major characteristic of HCC, antiangiogenic drugs have been tested. Areas covered: I...

journal_title：Expert opinion on pharmacotherapy

authors： Raoul JL,Gilabert M,Adhoute X,Edeline J

更新日期：2017-10-01 00:00:00

abstract：:alpha-adrenoceptor antagonists have traditionally been used in the treatment of hypertension but in recent years they have become increasingly common in the treatment of benign prostatic enlargement (BPE), where they reduce the 'dynamic' component of bladder outlet obstruction and appear to have additional actions to ...

journal_title：Expert opinion on pharmacotherapy

authors： Chess-Williams R

更新日期：2002-02-01 00:00:00

abstract：:Introduction: Multiple sclerosis (MS) is a demyelinating disease, causing axonal damage and disability. Dalfampridine (DAL) is an extended-release formulation of 4-aminopyridine (4AP) and broad-spectrum voltage-dependent potassium channel blocker that is reported to improve motor, visual and cognitive functions. Furth...

journal_title：Expert opinion on pharmacotherapy

authors： Foschi M,Lugaresi A

更新日期：2019-08-01 00:00:00

abstract：:A number of medicine selection methods have been used worldwide for formulary purposes. In Northern Ireland, integrated medicines management is being developed, and related projects have been carried out. This paper deals with the description of the STEPS (Safe Therapeutic Economic Pharmaceutical Selection) programme....

journal_title：Expert opinion on pharmacotherapy

authors： Scott M,Timoney M,Mairs J,Crealey G,Al Abaddi I,Brenninkmeijer R,Janknegt R,McElnay J

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease is thought to be caused by increased formations of neurotoxic amyloid beta (A beta) peptides, which give rise to the hallmark amyloid plaques. Therefore, pharmacological agents that reduce A beta formation may be of therapeutic benefit. OBJECTIVE:This paper reviews the pharmacology and c...

journal_title：Expert opinion on pharmacotherapy

authors： Henley DB,May PC,Dean RA,Siemers ER

更新日期：2009-07-01 00:00:00

abstract：:Motor fluctuations are common and distressing for patients with advanced Parkinson's disease. Subcutaneous apomorphine injections can be an extremely valuable adjunctive therapy. In this review, the authors discuss the history, pharmacology, efficacy, safety and proper administration of apomorphine for treating 'off' ...

journal_title：Expert opinion on pharmacotherapy

authors： Haq IU,Lewitt PA,Fernandez HH

更新日期：2007-11-01 00:00:00

abstract：:Introduction: Spondyloarthritis (SpA) refers to a group of disorders sharing common clinical, genetic and imaging characteristics. Axial (ax) SpA corresponds to a subgroup that mainly affects the axial skeleton, leading to inflammatory back pain and progressive radiographic changes of the sacroiliac joints and the spi...

journal_title：Expert opinion on pharmacotherapy

authors： Toussirot E

更新日期：2019-08-01 00:00:00

abstract：INTRODUCTION:Status epilepticus (SE) is a common neurological and medical emergency. It has high mortality and morbidity rates, which typically correlate with seizure semiology and duration; therefore, prompt and proper pharmacological intervention is paramount. In a pre-hospital setting, establishing venous access can...

journal_title：Expert opinion on pharmacotherapy

authors： Riva A,Iapadre G,Grasso EA,Balagura G,Striano P,Verrotti A

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Disturbances in lipid metabolism represent an integral component of dysglycemic states and may increase the risk of diabetic complications. Although from a pathophysiological viewpoint fibrates could represent the ideal drug for patients with diabetic dyslipidemia the evidence that support their use in the...

journal_title：Expert opinion on pharmacotherapy

authors： Tsimihodimos V,Mikhailidis DP,Elisaf M

更新日期：2013-12-01 00:00:00