Identification of G-proteins in rat parotid gland plasma membranes and granule membranes: presence of distinct components in granule membranes.

abstract：:The presence of a butyrylcholinesterase (BuChE, EC 3.1.1.8) in the musocal cells of the chicken intestine was demonstrated by histochemical and biochemical methods. The study of its distribution, along the intestine from duodenum to rectum, showed that the jejuno-ileum possesses the highest activity. Sucrose gradient ...

journal_title：Molecular and cellular biochemistry

authors： Sine JP,Ferrand R,Colas B

更新日期：1989-01-23 00:00:00

abstract：:Insulin elicits its divergent metabolic and mitogenic effects by binding to its specific receptor, which belongs to the family of receptor tyrosine kinases. The activated insulin receptor phosphorylates the intracellular substrate IRS-1, which then binds various signalling molecules that contain SRC homology 2 domains...

journal_title：Molecular and cellular biochemistry

authors： Ogawa W,Matozaki T,Kasuga M

更新日期：1998-05-01 00:00:00

abstract：:Cigarette smoking is associated with a number of fatal diseases, including cancer of different organs. A number of oxoaldehydes are found in cigarette smoke, among which methylglyoxal (MG) is known to cause toxicity to cells upon accumulation. In biological systems, MG is converted to s-d-lactoylglutathione by glyoxal...

journal_title：Molecular and cellular biochemistry

authors： Biswas S,Gairola CG,Das SK

更新日期：2002-01-01 00:00:00

abstract：:We measured the relative sliding velocity of cardiomyopathic hamster cardiac myosin on actin cables by using an in vitro motility assay system. We also investigated the relationship between the velocity and both myosin isozyme content and ATPase activity. Cardiac myosin was obtained from cardiomyopathic hamsters (BIO ...

journal_title：Molecular and cellular biochemistry

authors： Yamashita H,Sugiura S,Sata M,Serizawa T,Iizuka M,Shimmen T,Momomura S

更新日期：1993-02-17 00:00:00

abstract：:The regulation of the guinea-pig pancreatic acinar plasma membrane Ca2+ pump by protein kinase A, protein kinase C and calmodulin was investigated. The results were compared with the effects of these regulators on the high affinity Ca(2+)-ATPase found in this membrane preparation. The catalytic subunit of cyclic AMP-d...

journal_title：Molecular and cellular biochemistry

authors： Mahey R,Allen BG,Bridges MA,Katz S

更新日期：1992-06-26 00:00:00

abstract：:Autism is a prevalent developmental disorder that combines repetitive behaviours, social deficits and language abnormalities. The present study aims to assess the autistic subjects using DSM IV-TR criteria followed with the analysis of neurotransmitters, biochemical parameters, oxidative stress and its ions in two gro...

journal_title：Molecular and cellular biochemistry

authors： Meyyazhagan A,Balasubramanian B,Easwaran M,Alagamuthu KK,Shanmugam S,Kuchi Bhotla H,Pappusamy M,Arumugam VA,Thangaraj A,Kaul T,Keshavarao S,Cacabelos R

更新日期：2020-11-01 00:00:00

abstract：:One of the atrial natriuretic factor (ANF) receptors is a 180 kDa protein (180 kDa mGC) which possesses the extraordinary characteristic of being bifunctional: it is both a receptor and a guanylate cyclase. In addition to the 180 kDa mGC, there exists another 120-130 kDa protein which is also bifunctional and a 120 kD...

journal_title：Molecular and cellular biochemistry

authors： Marala RB,Sharma RK

更新日期：1992-01-15 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) has been thought to play a major role during cardiac fibrosis in the development of diabetic cardiomyopathy, and cardiac fibrosis mainly as a result of an increase of collagen type III occurs in the human hearts with diabetes. Thrombospondin-1 (TSP-1) has been reported to activat...

journal_title：Molecular and cellular biochemistry

authors： Tang M,Zhou F,Zhang W,Guo Z,Shang Y,Lu H,Lu R,Zhang Y,Chen Y,Zhong M

更新日期：2011-01-01 00:00:00

abstract：:This study aimed to explore the potential contribution of myofibrils to contractile dysfunction in Ca2+-paradox hearts. Isolated rat hearts were perfused with Krebs-Henseleit solution (Control), followed by Ca2+-depletion, and then Ca2+-repletion after Ca2+-depletion (Ca2+-paradox) by Langendorff method. During heart ...

journal_title：Molecular and cellular biochemistry

authors： Kovács Á,Kalász J,Pásztor ET,Tóth A,Papp Z,Dhalla NS,Barta J

更新日期：2017-06-01 00:00:00

abstract：:An arginase isolated from a capsulated Bacillus anthracis strain was highly purified and crystallized. The chemical and immunological characteristics of this enzyme re described. Some very important properties differ from those of another bacterial arginase, i.e. Staphylococcus aureus arginase, described in a previous...

journal_title：Molecular and cellular biochemistry

authors： Soru E

更新日期：1983-01-01 00:00:00

abstract：:A matricellular protein, osteopontin (OPN), is expressed in response to mechanical stress and similar stimuli in the heart, integrates the inter-ECM signal transduction network of component cells, and maintains efficient contractility through quantitative and qualitative control of extracellular matrix (ECM) proteins....

journal_title：Molecular and cellular biochemistry

authors： Okamoto H

更新日期：2007-06-01 00:00:00

abstract：:The interaction of glyceraldehyde 3-phosphate dehydrogenase with microtubules has been studied by measurement of the amount of enzyme which co-assembles with in vitro reconstituted microtubules. The binding of glyceraldehyde 3-phosphate dehydrogenase to microtubules is a saturable process; the maximum binding capacity...

journal_title：Molecular and cellular biochemistry

authors： Durrieu C,Bernier-Valentin F,Rousset B

更新日期：1987-03-01 00:00:00

abstract：:Workers who are exposed to extreme heat or work in hot environments may be at risk of heat stress. Exposure to extreme heat can result in occupational illnesses and injuries. On the other hand, local and regional heat therapy has been used for the treatment of some cancers, such as liver cancer, lung cancer, and kidne...

journal_title：Molecular and cellular biochemistry

authors： Han J,Xu X,Qin H,Liu A,Fan Z,Kang L,Fu J,Liu J,Ye Q

更新日期：2013-06-01 00:00:00

abstract：:Tumor necrosis factor receptor-associated factor 6 (TRAF6), a regulator of NF-κB signaling, has been discovered recently to be probably related to osteoarthritis, while the function of TRAF6 in lumbar facet joint osteoarthritis(FJOA)still remains unknown. The aim of this study was to probe the specific function of TRA...

journal_title：Molecular and cellular biochemistry

authors： Jiang J,Zhang J,Wu C,Chen C,Bao G,Xu G,Xue P,Zhou Y,Sun Y,Cui Z

更新日期：2021-01-27 00:00:00

abstract：UNLABELLED:Inhibition of Na+/H+ exchange with amiloride analogues has been shown to provide functional protection during ischemia and reperfusion and to reduce infarct size in isolated rat hearts. In rat hearts, treatment with ethylisopropyl-amiloride (EIPA, a selective Na+/H- exchange inhibitor) was additive to the pr...

journal_title：Molecular and cellular biochemistry

authors： Munch-Ellingsen J,Løkebø JE,Bugge E,Ytrehus K

更新日期：1998-09-01 00:00:00

abstract：:We evaluated the effects of Rubus tereticaulis in healing process by determining the total carbonyl content, collagen synthesis, and total protein level on rat wounded tissues. Wounds were performed in the back of 54 Wistar rats, using a biopsy punch instrument with 0.6 mm in diameter. Rats were randomly divided into ...

journal_title：Molecular and cellular biochemistry

authors： Aksoy H,Demirbağ Ç,Şen A,Şekerler T,Özakpınar Ö,Şener A,Ahmad S,Tetik S

更新日期：2020-09-01 00:00:00

abstract：:Previous results from our laboratory have shown that a novel carotenoid derivative (disodium disuccinate astaxanthin; Cardax) produced dose-related reductions in myocardial infarct size (IS) in Sprague-Dawley rats when it was administered at any of three doses (25, 50 and 75 mg/kg, iv) on four consecutive days, follow...

journal_title：Molecular and cellular biochemistry

authors： Gross GJ,Lockwood SF

更新日期：2005-04-01 00:00:00

abstract：:Sodium cyanide (NaCN)-induced chemical hypoxia is known to increase intracellular free calcium concentration and reduce cell survival, but its effect on gene expression has not been studied. In this study, we designed primers to conduct a rapid and reliable assay for the expression of mRNA of inducible nitric oxide sy...

journal_title：Molecular and cellular biochemistry

authors： Kiang JG,Warke VG,Tsokos GC

更新日期：2003-12-01 00:00:00

abstract：:DEAE-cellulose column chromatography of Neurospora crassa soluble mycelial extracts leads to the resolution of three major protein kinase activity peaks designated PKI, PKII, and PKIII. PKII activity is stimulated by Ca2+ and Neurospora or brain calmodulin. Maximal stimulation was observed at 2 microM-free Ca2+ and 1 ...

journal_title：Molecular and cellular biochemistry

authors： Ulloa RM,Torres HN,Ochatt CM,Téllez-Iñón MT

更新日期：1991-04-10 00:00:00

abstract：:Regulation of matrix metalloproteinase-13 (MMP-13) by collagen matrix in the synovial fibroblasts of rheumatoid arthritis (RA) is critical event in the progressive joint destruction. Our previous study indicated that a collagen receptor, discoidin receptor 2 (DDR2), was highly expressed in the synovial fibroblasts of ...

journal_title：Molecular and cellular biochemistry

authors： Su J,Yu J,Ren T,Zhang W,Zhang Y,Liu X,Sun T,Lu H,Miyazawa K,Yao L

更新日期：2009-10-01 00:00:00

abstract：:Parkinson disease (PD) is a neurodegenerative disease characterized by progressive dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) area. The present study was undertaken to evaluate the neuroprotective effect of β-caryophyllene (BCP) against rotenone-induced oxidative stress and neuroinflamm...

journal_title：Molecular and cellular biochemistry

authors： Ojha S,Javed H,Azimullah S,Haque ME

更新日期：2016-07-01 00:00:00

abstract：:Cyclophosphamide (CP), an alkylating agent widely used in cancer chemotherapy causes cardiac membrane damage. Lupeol, a pentacyclic triterpene, isolated from Crataeva nurvala stem bark and its ester, lupeol linoleate possess a wide range of medicinal properties. The effect of lupeol and its ester was evaluated in CP i...

journal_title：Molecular and cellular biochemistry

authors： Sudharsan PT,Mythili Y,Selvakumar E,Varalakshmi P

更新日期：2006-11-01 00:00:00

abstract：:Control of mitochondrial respiration depends on ADP availability to the F1-ATPase. An electrochemical gradient of ADP and ATP across the mitochondrial inner membrane is maintained by the adenine nucleotide translocase which provides ADP to the matrix for ATP synthesis and ATP for energy-dependent processes in the cyto...

journal_title：Molecular and cellular biochemistry

authors： McMillin JB,Pauly DF

更新日期：1988-06-01 00:00:00

abstract：:In the context of high human consumption of fructose diets, there is an imperative need to understand how dietary fructose intake influence cellular and molecular mechanisms and thereby affect β-cell dysfunction and insulin resistance. While evidence exists for a relationship between high-fat-induced insulin resistanc...

journal_title：Molecular and cellular biochemistry

authors： Balakumar M,Raji L,Prabhu D,Sathishkumar C,Prabu P,Mohan V,Balasubramanyam M

更新日期：2016-12-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is one of the rare cancers in western countries but predominant in Southeast Asian countries including Thailand. One major cause for failure of NPC chemotherapeutic treatments is reportedly correlated with the elevation of cancer stem cell (CSC) fractions. Thus, this present study aims t...

journal_title：Molecular and cellular biochemistry

authors： Sinnung S,Janvilisri T,Kiatwuthinon P

更新日期：2021-01-09 00:00:00

abstract：:In myocardial cells (MCs), endothelin-1 (ET-1) exerts various effects such as hypertrophy, and causes cellular injury. Long-term treatment with an endothelin-A (ET(A)) receptor antagonist improves the survival of rats with heart failure, suggesting that myocardial endothelin system contributes to the progression of he...

journal_title：Molecular and cellular biochemistry

authors： Ueyama T,Kawashima S,Sakoda T,Rikitake Y,Ishida T,Kawai M,Namiki M,Yokoyama M

更新日期：1999-09-01 00:00:00

abstract：:Striatal neuronal cell death is one of the pathological features of Huntington's disease (HD). Overexpression of some heat shock proteins (HSPs) has been reported to suppress the aggregate formation of mutant huntingtin and concurrent cell death. Heat shock transcription factor-1 (HSF 1), a major transcription factor ...

journal_title：Molecular and cellular biochemistry

authors： Choi YJ,Om JY,Kim NH,Chang JE,Park JH,Kim JY,Lee HJ,Kim SS,Chun W

更新日期：2013-03-01 00:00:00

abstract：:Effect of several vanadium salts, sodium orthovanadate, vanadyl sulfate and sodium metavanadate on protein tyrosine phosphorylation and serine/threonine kinases in chinese hamster ovary (CHO) cells overexpressing a normal human insulin receptor was examined. All the compounds stimulated protein tyrosine phosphorylatio...

journal_title：Molecular and cellular biochemistry

authors： Pandey SK,Chiasson JL,Srivastava AK

更新日期：1995-12-06 00:00:00

abstract：:Etomoxir, an inhibitor of mitochondrial carnitine palmitoyltransferase-1, is known to attenuate the changes in myosin isoforms and sarcoplasmic reticular function that occur in diabetic rat hearts. In the present study, we tested the hypothesis that etomoxir also prevents the diabetes-induced depression of sarcolemmal...

journal_title：Molecular and cellular biochemistry

authors： Kato K,Lukas A,Chapman DC,Rupp H,Dhalla NS

更新日期：2002-03-01 00:00:00

abstract：:Left ventricular hypertrophy (LVH) increases the risk of cardiovascular morbid events in hypertension. TGF-beta1 is involved in pathologic states such as cardiac hypertrophy and cardiac fibrosis; we thus postulate that the TGF-beta1 polymorphism is related to LVH in hypertensives. Six hundred and eighty essential hype...

journal_title：Molecular and cellular biochemistry

authors： Xu HY,Hou XW,Wang LF,Wang NF,Xu J

更新日期：2010-02-01 00:00:00