Abstract:
BACKGROUND:Recent reports have highlighted the lifetime risk of malignancy from using ionizing radiation in pediatric imaging. Computed tomography (CT), which uses ionizing radiation, is employed extensively for neonatal brain imaging of term infants. Magnetic resonance (MR) provides an alternative that does not use ionizing radiation. OBJECTIVE:The purpose of this study was to assess the cross-modality agreement and interobserver agreement of CT and MR brain imaging of the term or near-term neonate. MATERIALS AND METHODS:Brain CT and MR images of 48 neonates were retrospectively reviewed by two pediatric neuroradiologists. CT and MR examinations had been obtained within 72 h of one another in all patients. CT was obtained with 5 mm collimation (KV=120, mAs=340). MR consisted of T1-weighted imaging (TR/TE=300/14; 4-mm slice thickness/1-mm gap), T2-weighted imaging (TR/TE/etl= 3000/126/16; 4-mm slice thickness/1-mm gap), and line scan diffusion imaging (LSDI) (TR/TE/b factor=1258/63/750; nominal 4-mm slice thickness/3-mm gap). The brain was categorized as normal or abnormal on both CT and MR. RESULTS:Ischemic injury was the most common brain abnormality demonstrated. McNemar's test indicated no significant difference between CT and MR test results for reader 1 (P=0.22) or reader 2 (P=0.45). The readers agreed on the presence or absence of abnormality on CT in 40 patients (83.3%) and on MR in 45 patients (93.8%). For CT, the kappa coefficient indicated excellent interobserver agreement (kappa=0.68), although the lower limit of the 95% confidence interval extends to kappa=0.55, which indicates only good-to-moderate agreement. For MR, the kappa coefficient indicated almost perfect interobserver agreement (kappa=0.88) with the 95% confidence interval extending to a lower limit of kappa=0.76, which represents excellent agreement. CONCLUSION. Because MR demonstrates findings similar to CT and has greater interobserver agreement, it appears that MR is a superior test to CT in determining brain abnormalities in the term neonate. Furthermore, since MR eliminates the use of ionizing radiation, a putative cause of malignancy, it should be the standard in neonatal brain imaging. Future efforts should be directed to improving neonatal access to MR to avoid the routine use of CT in infants.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Robertson RL,Robson CD,Zurakowski D,Antiles S,Strauss K,Mulkern RVdoi
10.1007/s00247-003-0933-6keywords:
subject
Has Abstractpub_date
2003-07-01 00:00:00pages
442-9issue
7eissn
0301-0449issn
1432-1998journal_volume
33pub_type
杂志文章abstract:BACKGROUND:Dose reduction by combined tube current modulation has not been evaluated in pediatric low-dose CT. OBJECTIVE:This study was performed to evaluate tube current reduction in non-ECG-gated heart CT angiography in children by combined tube current modulation, and to assess the effects of body weight, age, sex,...
journal_title:Pediatric radiology
pub_type: 临床试验,杂志文章
doi:10.1007/s00247-005-0105-y
更新日期:2006-04-01 00:00:00
abstract::Omental cyst is a rare lesion occurring primarily during childhood and young adulthood. It is closely related to mesenteric and retroperitoneal cysts, all conditions most likely being of congenital or benign neoplastic lymphatic origin. Omental cysts usually present as abdominal distention of long duration, less frequ...
journal_title:Pediatric radiology
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doi:10.1007/BF01006901
更新日期:1975-06-13 00:00:00
abstract::Lipoprotein lipase deficiency (LLD) is a rare metabolic disorder that typically presents with skin xanthomas and pancreatitis in childhood. We report a case of LLD in an infant who presented with jaundice caused by a pancreatic head mass. Abdominal imaging also incidentally revealed hyperechoic renal masses caused by ...
journal_title:Pediatric radiology
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更新日期:2010-08-01 00:00:00
abstract::Children with malignancies undergo recurrent imaging as part of tumor diagnosis, staging and therapy response assessment. Simultaneous positron emission tomography (PET) and magnetic resonance (MR) allows for decreased radiation exposure and acts as a one-stop shop for disease in which MR imaging is required. Neverthe...
journal_title:Pediatric radiology
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abstract:BACKGROUND:A technique for reinsertion of an inadvertently removed tunneled central venous catheter is presented. A 6-year-old boy with short-gut syndrome caused by necrotizing enterocolitis accidentally removed his tunneled central venous catheter. MATERIALS AND METHODS:The existing subcutaneous catheter tract was re...
journal_title:Pediatric radiology
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更新日期:1999-12-01 00:00:00
abstract::We prospectively evaluated a group of patients with sickle cell disease and a clinical history of prior stroke, comparing transcranial Doppler sonography (TCD) to both magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) to determine its efficacy for the detection of flow abnormalities associated ...
journal_title:Pediatric radiology
pub_type: 临床试验,杂志文章
doi:10.1007/BF02012192
更新日期:1994-01-01 00:00:00
abstract::Historically, the first case of congenital prepyloric membrane in an infant was documented in 1933 [1]. Since then cases have been reported only sporadically in the literature [2-8]. This is a case of congenital antral web which was identified by real-time ultrasonography, confirmed by barium meal study, and proven at...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02016251
更新日期:1992-01-01 00:00:00
abstract::Hepatocyte-specific contrast media are gadolinium chelates that are taken up by hepatocytes and partially cleared via the biliary tree. The absence of lesional uptake of the contrast media in the hepatobiliary phase is a marker of either the absence of hepatocytes or of poorly functioning, neoplastic hepatocytes. Upta...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-018-4108-x
更新日期:2018-08-01 00:00:00
abstract::A case of duodenal diaphragm diagnosed by ultrasound is presented. The case was associated with situs inversus. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388285
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Many intervention studies in preterm infants aim to improve neurodevelopmental outcome, but short-term proxy outcome measurements are lacking. Cortical plate and subplate development could be such a marker. OBJECTIVE:Our aim was to provide normal DTI reference values for the cortical plate and subplate of p...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-010-1638-2
更新日期:2010-08-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050121
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:Hepatic involvement is frequent in patients with cystic fibrosis (CF), with focal biliary cirrhosis being the pathognomonic hepatic manifestation. In around one-quarter of CF patients, it results in CF-associated liver disease (CFLD). This occurs as a relatively early complication with the majority of patien...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-009-1531-z
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Food allergy may be partly due to impairment of the intestinal barrier and is frequently associated with atopic dermatitis (AD) in early life. OBJECTIVE:To determine whether bowel wall thickening, as demonstrated by US, is useful for the identification of food allergy. MATERIALS AND METHODS:We used US to s...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-001-0593-3
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Fetal MRI at 3 T is associated with increased acoustic noise relative to 1.5 T. OBJECTIVE:The goal of this study is to determine if there is an increased prevalence of congenital hearing loss in neonates who had a 3-T prenatal MR vs. those who had it at 1.5 T. MATERIALS AND METHODS:We retrospectively ident...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-018-4261-2
更新日期:2019-01-01 00:00:00
abstract::The approach to breast masses in children differs from that in adults in many ways, including the differential diagnostic considerations, imaging algorithm and appropriateness of biopsy as a means of further characterization. Most pediatric breast masses are benign, either related to breast development or benign neopl...
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pub_type: 杂志文章,评审
doi:10.1007/s00247-015-3402-0
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Children with hepatoblastoma routinely undergo repetitive surveillance imaging, with CT scans for several years after therapy, increasing the risk of radiation-induced cancer. OBJECTIVE:The purpose of this study was to determine the utility of surveillance CT scans compared to serum alpha-fetoprotein (AFP) ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-014-3000-6
更新日期:2014-10-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-008-0965-z
更新日期:2008-12-01 00:00:00
abstract::This paper describes the imaging features of ovarian metastases from adenocarcinoma of the colon in adolescent females. We reviewed retrospectively abdominal and pelvic computed tomographic and pelvic ultrasound examinations, histologic slices, and clinical charts of six adolescent females with ovarian metastases seco...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02011103
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:White matter maturation is characterised by increasing fractional anisotropy (FA) and decreasing mean diffusivity (MD). Contradictory results have been published on the effect of premature birth on white matter maturation at term-equivalent age. OBJECTIVE:To assess the association of gestational age and low...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-012-2352-z
更新日期:2012-06-01 00:00:00
abstract::A previously healthy 24-day-old boy presented with a 2-day history of fever and had a convulsion on the day of admission. MRI showed abnormal signal in the thalami, caudate nuclei and central white matter. Acute necrotising encephalopathy was diagnosed, other causes having been excluded after biochemical and haematolo...
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pub_type: 杂志文章
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更新日期:2003-09-01 00:00:00
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journal_title:Pediatric radiology
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更新日期:1984-01-01 00:00:00
abstract:PURPOSE:To describe the CT features of complicated pleural tuberculosis in children and to define the use of CT in children with pleural tuberculosis. MATERIALS AND METHODS:The CT findings in 11 children with complicated pleural tuberculosis were retrospectively analysed. CT was performed to evaluate persistent pleura...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050561
更新日期:1999-03-01 00:00:00
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更新日期:2012-09-01 00:00:00
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journal_title:Pediatric radiology
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更新日期:1992-01-01 00:00:00
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journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-006-0253-8
更新日期:2006-10-01 00:00:00
abstract::Sporotrichosis in children is rare, and its osteoarticular form is very unusual. Disseminated forms are described mostly in immunocompromised patients. We report a case of a 5-year-old immunocompetent boy with multiple suppurated cutaneous lesions that progressed to polyarthritis of the hands and feet. Radiographic im...
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更新日期:2015-08-01 00:00:00
abstract::The development of lipid aspiration pneumonia after chronic nasopharyngeal installation of mineral oil was first described in 1925 by Laughlin. Since that time this entity has been well recognized and numerous substances have been identified or implicated as the aspirated material. The classic radiographic appearance ...
journal_title:Pediatric radiology
pub_type: 杂志文章
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更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:Pulmonary alveolar proteinosis (PAP) is characterized by an abnormal accumulation of periodic acid-schiff-positive lipoproteinaceous material in the alveoli. Early diagnosis allows setting up of therapeutic lung lavages, which reduces the need for oxygen supplementation and weight gain. OBJECTIVE:To provide...
journal_title:Pediatric radiology
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更新日期:2014-07-01 00:00:00
abstract::This case report describes the incidental finding of intestinal leakage during bone scan imaging with Tc-99m methylene diphosphonate (MDP) in a patient with previously diagnosed protein-losing enteropathy (PLE). Most radiopharmaceuticals reported in the literature that are useful for making this diagnosis are not gene...
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更新日期:2008-10-01 00:00:00
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