Role of intestinal epithelial apoptosis in survival.

abstract：:Radiocontrast nephropathy may in part be mediated by generation of reactive oxygen species causing direct toxic damage to renal tubular epithelial cell and renal medullary ischemia. Data from experimental studies indicated that antioxidants, eg, acetylcysteine, may prevent radiocontrast-induced nephropathy. Recently, ...

journal_title：Current opinion in critical care

authors： Tepel M,Zidek W

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The use of neuromuscular blocking agents (NMBAs) in patients with acute respiratory distress syndrome (ARDS) and acute lung injury remains controversial, although frequent. This review analyzes the effects of NMBAs on thoracopulmonary mechanics, gas exchange, patient outcome and their potential advers...

journal_title：Current opinion in critical care

authors： Forel JM,Roch A,Papazian L

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Nutritional status and nutrient delivery during critical illness impact clinical outcomes. We have reviewed recent studies that may guide best practices regarding nutrition therapy in critically ill children. RECENT FINDINGS:Malnutrition is prevalent in the pediatric ICU population, and is associated...

journal_title：Current opinion in critical care

authors： Martinez EE,Mehta NM

更新日期：2016-08-01 00:00:00

abstract：:Clinicians are increasingly aware that fungal pathogens are a significant cause of morbidity and mortality in hospitalized patients. Historically, these infections occurred in severely immunocompromised patients who were undergoing treatment for hematological malignancy or solid organ transplantation. Currently, howev...

journal_title：Current opinion in critical care

authors： Rogers TR

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Care surrounding end-of-life has become a major topic in the intensive care medicine literature. Cultural and regional variations are associated with transatlantic debates about decisions to forego life-sustaining therapies and lead to recent international statements. The aim of this review is to prov...

journal_title：Current opinion in critical care

authors： Fassier T,Lautrette A,Ciroldi M,Azoulay E

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:We report on recent advances and achievements on the use of extracorporeal gas exchange for long-term application in the therapy of critically ill patients with various forms of respiratory failure. RECENT FINDINGS:The most important results regarding the use of extracorporeal gas exchange are expect...

journal_title：Current opinion in critical care

authors： Pesenti A,Zanella A,Patroniti N

更新日期：2009-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite improved care of multiple injured patients, controversial data about the best time point for decompression and stabilization of spine fractures and spinal cord injuries are published. Some studies even question the value of surgical management. RECENT FINDINGS:In several mostly retrospective ...

journal_title：Current opinion in critical care

authors： Schinkel C,Anastasiadis AP

更新日期：2008-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Although vitamin C is essentially a nontoxic vitamin; however, it is important to be aware regarding the safety of high doses before the wide clinical use. RECENT FINDINGS:Minor side effects of vitamin C have been reported, many being reported in earlier studies. High doses of vitamin C (up to 1.5 g/...

journal_title：Current opinion in critical care

authors： Khoshnam-Rad N,Khalili H

更新日期：2019-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Early detection of gastrointestinal motility disturbances is a major goal to reduce the incidence of this potentially disastrous event by prophylactic managements and early goal-directed therapy in patients at risk. RECENT FINDINGS:Gastroparesis frequently results in the inability to feed critically ...

journal_title：Current opinion in critical care

authors： Fruhwald S,Kainz J

更新日期：2010-04-01 00:00:00

abstract：:During the past decade, enormous advances have been made in cell biology. Major advances included the publication of the human genome sequence, the development of proteomics, and DNA microarray technologies and techniques to selectively "silence" genes using short strands of double-stranded RNA. Some areas of great pr...

journal_title：Current opinion in critical care

authors： Fink MP

更新日期：2004-08-01 00:00:00

abstract：:This review discusses the myocardial protective property of the insulin/glucose-insulin-potassium regimen and the mechanisms involved in this beneficial action. Several recent studies suggest that insulin not only is useful to control hyperglycemia and maintain glucose homeostasis but also may have the unique property...

journal_title：Current opinion in critical care

authors： Das UN

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome has been considered a morphologic and functional expression of lung injury caused by a variety of insults. Two distinct forms of acute respiratory distress syndrome/acute lung injury are described, because there are differences between pulmonary acute respiratory di...

journal_title：Current opinion in critical care

authors： Rocco PR,Zin WA

更新日期：2005-02-01 00:00:00

abstract：:Intra-abdominal infection continues to pose a significant threat to critically ill patients in the year 2000. A review of the current literature reveals that despite remarkable developments in critical care medicine and extensive study of patients with tertiary peritonitis, the associated mortality rate remains nearly...

journal_title：Current opinion in critical care

authors： Evans HL,Raymond DP,Pelletier SJ,Crabtree TD,Pruett TL,Sawyer RG

更新日期：2001-04-01 00:00:00

abstract：PURPOSE OF REVIEW:When classic examinations such as bronchoalveolar lavage are not contributory in the etiologic diagnosis of unresolving acute respiratory distress syndrome, surgical lung biopsy would appear to be useful to determine the specific cause, particularly infection or postaggressive fibrosis, which could be...

journal_title：Current opinion in critical care

authors： Donati SY,Papazian L

更新日期：2008-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the role of the invasive monitoring techniques pulmonary artery catheter (PAC) and transpulmonary thermodilution (TPD) for cardiopulmonary monitoring in the critically ill patient. RECENT FINDINGS:Characterization of the nature of hemodynamic alterations and hemodynamic optimization can be...

journal_title：Current opinion in critical care

authors： De Backer D,Fagnoul D,Herpain A

更新日期：2013-06-01 00:00:00

abstract：:Reactive oxygen species are reactive, partially reduced derivatives of molecular oxygen (O 2 ). Important reactive oxygen species in biologic systems include superoxide radical anion, hydrogen peroxide, and hydroxyl radical. Closely related species include the hypohalous acids, particularly hypochlorous acid; chlorami...

journal_title：Current opinion in critical care

authors： Fink MP

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review will discuss the rationale and clinical utility of percutaneous left ventricular assist devices in the management of patients with cardiogenic shock. RECENT FINDINGS:Left ventricular assist devices maintain partial or total circulatory support in case of severe left ventricular failure. C...

journal_title：Current opinion in critical care

authors： Windecker S

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Treatment protocols targeting the rapid administration of appropriate antibiotics and hemodynamic support are now recognized as a key measure in the initial care of patients presenting with severe sepsis and septic shock. Strong evidence exists showing that time parameters, particularly in the emergen...

journal_title：Current opinion in critical care

authors： Nobre V,Sarasin FP,Pugin J

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The ultimate goal of cardiopulmonary resuscitation is long-term neurologically intact survival. Despite numerous well-designed studies, the medications currently used in advanced cardiac life support have not demonstrated success in this regard. This review describes the novel therapeutics under inves...

journal_title：Current opinion in critical care

authors： Bartos JA,Yannopoulos D

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the review is to summarize and discuss recent research regarding the role of mechanical ventilation in producing weakness and atrophy of the diaphragm in critically ill patients, an entity termed ventilator-induced diaphragmatic dysfunction (VIDD). RECENT FINDINGS:Severe weakness of th...

journal_title：Current opinion in critical care

authors： Petrof BJ,Hussain SN

更新日期：2016-02-01 00:00:00

abstract：:Widespread provision of early defibrillation following cardiac arrest holds major promise for improved survival from ventricular fibrillation. The critical element in predicting a successful outcome is the rapidity with which defibrillation is achieved. A worldwide awareness of this potential and its advocacy by such ...

journal_title：Current opinion in critical care

authors： White RD

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Professional organizations, consensus groups, and stakeholders are calling for better palliative care in acute care settings, particularly in ICUs. Our ability to deliver that care is dependent on the outcomes associated with palliative care in the ICU. This review provides a conceptual framework for ...

journal_title：Current opinion in critical care

authors： Aslakson RA,Bridges JF

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Delirium is frequently encountered in the ICU and is associated with significant adverse outcomes. The increasingly recognized consequences of ICU delirium should enhance efforts to improve recognition and management of this serious problem. We aim to review the recent literature on ICU delirium, incl...

journal_title：Current opinion in critical care

authors： Jones SF,Pisani MA

更新日期：2012-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Energy dysfunction is increasingly recognized as a key factor in the pathogenesis of acute brain injury (ABI). This one characterized by a high metabolic rate and nitrogen loss is often associated with an undernutrition support. We review the metabolism evolution and nutritional status in brain injure...

journal_title：Current opinion in critical care

authors： Quintard H,Ichai C

更新日期：2019-04-01 00:00:00

abstract：PURPOSE OF REVIEW:We sought to review the evidence supporting neurocritical care as a distinct specialty of medicine. RECENT FINDINGS:Over the past 20 years, neuro-intensive care units have evolved from neurosurgical units focused primarily on postoperative monitoring to units that provide comprehensive medical and sp...

journal_title：Current opinion in critical care

authors： Rincon F,Mayer SA

更新日期：2007-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The liver comprises a multitude of parenchymal and nonparenchymal cells with diverse metabolic, hemodynamic and immune functions. Available monitoring options consist of 'static' laboratory parameters, quantitative tests of liver function based on clearance, elimination or metabolite formation and sco...

journal_title：Current opinion in critical care

authors： Kortgen A,Recknagel P,Bauer M

更新日期：2010-04-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose is to review the current application of extracorporeal life support (ECLS) in trauma patients. In addition, programmatic development is described. RECENT FINDINGS:ECLS use is increasing among trauma patients. Several recent studies among trauma patients report survival rates of 65-79%. De...

journal_title：Current opinion in critical care

authors： Zonies D,Merkel M

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Multimodal monitoring has emerged as a novel paradigm of care in acute brain injury, and in this context the value of noninvasive devices is increasingly under scrutiny. This narrative review summarizes recent clinical investigation focused on the role of automated infrared pupillometry (AIP) and opti...

journal_title：Current opinion in critical care

authors： Romagnosi F,Bongiovanni F,Oddo M

更新日期：2020-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Uncertainty surrounding medical decision-making is particularly important during end-of-life decision-making. Doubts about the patient's best interests and prognostic accuracy may lead to conflict. RECENT FINDINGS:Many authors have suggested recently that medical attitudes to uncertainty need review....

journal_title：Current opinion in critical care

authors： Ridley S,Fisher M

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:From an elderly patient's perspective, acute and chronic cognitive disturbances are among the most harmful complications that can occur following surgery. For elderly patients, these complications often mean the end of an independent life. This article focuses on this serious aspect, which is increasi...

journal_title：Current opinion in critical care

authors： Müller A,Lachmann G,Wolf A,Mörgeli R,Weiss B,Spies C

更新日期：2016-08-01 00:00:00