Abstract:
BACKGROUND:Adverse influences arising in fetal life or immediately after birth have a permanent effect on body structure, physiology and metabolism. Evidence is now accumulating that programming of bone growth might be an important contributor to the later risk of osteoporosis. Long-term morbidity and mortality associated with retralogy of Fallot is not completely known. The aim of the present study was to evaluate the state of the bones in adolescents after surgical repair of tetralogy of Fallot, so as to ascertain any possible repercussions of the disease on bone mineralization. MATERIAL AND METHODS:We studied 34 adolescents with repaired tetralogy of Fallot, between the ages of 11 and 18 years, to establish their nutritional status, in terms of height, weight, and skinfolds, their body composition using an anthropometric method, their sexual maturity according to Tanner, and their food-habits as based on 24-hour recall. Bone density was evaluated by lumbar dual-energy X-ray absorptiometry. We included 34 healthy eutrophic adolescents, matched for gender and age, as controls. RESULTS:No significant differences were observed between the patients and their controls concerning nutritional status, body composition, total energy intake and nutritional supply in macronutrients, calcium, phosphorus, magnesium and vitamin D. Bone mineral density, expressed in Z-score and g/cm2, was significantly higher in patients with tetralogy of Fallot (p < 0.01). The age at the time of the first surgical procedure, or at complete surgical repair, and the total number of surgical procedures, had no significant influence on nutritional status or bone mineralization. Gender, chronological age, sexual maturity and the index of body mass are the major determinants of bone density for both samples. Obese adolescents with repaired tetralogy of Fallot had a significantly higher bone density (p < 0.05) compared to undernourished or euthrophic patients. CONCLUSIONS:Being born with tetralogy of Fallot has no significant repercussion, by the stage of adolescence, on nutritional status, pubertal progression, and accretion of bone minerals subsequent to surgical repair. Nutritional status is the major influence on the accretion of bone mass.
journal_name
Cardiol Youngjournal_title
Cardiology in the youngauthors
Rego C,Guerra A,Guardiano M,Esteves P,Pereira J,Aguiar A,Areias JCdoi
10.1017/s1047951102000963keywords:
subject
Has Abstractpub_date
2002-12-01 00:00:00pages
531-6issue
6eissn
1047-9511issn
1467-1107journal_volume
12pub_type
杂志文章abstract::We studied the duration and dispersion of the P wave in patients after a Senning operation, assessing its value in detecting the risk of atrial tachycardias.We measured the duration and dispersion of the wave in surface 12 lead electrocardiograms obtained from 18 patients with sinus rhythm, having a mean age of 12.8 y...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951109991892
更新日期:2009-12-01 00:00:00
abstract::The anomalous aortic origin of a coronary artery from the wrong sinus of Valsalva with interarterial, intramural, and/or intraconal course is a rare congenital anomaly that is associated with a high risk of sudden death in children. The Congenital Heart Surgeons' Society established the Registry of Anomalous Aortic Or...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001095
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:To describe endovascular stent placement using partially covered stents to preserve flow in head and neck vessels. BACKGROUND:Endovascular stent placement has become established as a first-line therapy for native coarctation of the aorta or re-coarctation in older children and adults. Increasingly covered st...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951112000236
更新日期:2012-10-01 00:00:00
abstract::The incidence of congenital heart disease is higher in monozygotic than dizygotic twins, with a higher concordance rate. Although coarctation of the aorta has previously been reported in monozygotic twins, to the best of our knowledge it has not been described in dizygotic twins. We report here such a concurrence in d...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951100006375
更新日期:2000-01-01 00:00:00
abstract:AIMS:To assess results of closure of atrial septal defects within the oval fossa by devices delivered by catheterisation in symptomatic infants and children under 2 years of age. METHODS AND RESULTS:The Amplatzer septal occluder was used. Results, and complications of transcatheter device treatment in patients aged be...
journal_title:Cardiology in the young
pub_type: 临床试验,杂志文章
doi:10.1017/s1047951100008234
更新日期:2000-09-01 00:00:00
abstract::Infants with hypoplastic left heart syndrome often experience difficulty with oral feeding, which contributes to growth failure, morbidity, and mortality. In response to feeding difficulty, clinicians often change the bottle nipple, and thus milk flow rate. Slow-flow nipples have been found to reduce the stress of fee...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116000251
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:We evaluated the safety and feasibility of high-intensity interval training via a novel telemedicine ergometer (MedBIKE™) in children with Fontan physiology. METHODS:The MedBIKE™ is a custom telemedicine ergometer, incorporating a video game platform and live feed of patient video/audio, electrocardiograp...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120002097
更新日期:2020-10-01 00:00:00
abstract::The mitral-aortic intervalvular fibrosa is an area of fibrous continuity between the mitral and aortic valves. We present the first case of a congenital pseudoaneurysm in this region, detected prenatally as an isolated cardiac defect, which was followed-up conservatively postnatally. The diagnosis was confirmed by ech...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117000890
更新日期:2017-05-29 00:00:00
abstract::Supravalvular aortic stenosis is associated with the Williams-Beuren syndrome, but it also occurs in a non-syndromatic congenital form. An elastin gene mutation of chromosome 7q11.23 is responsible in both cases. The vascular features are identical. These patients have a higher risk of sudden death, particularly when ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001563
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Diaphragm dysfunction following surgery for congenital heart disease is a known complication leading to delays in recovery and increased post-operative morbidity and mortality. We aimed to determine the incidence of and risk factors associated with diaphragm plication in children undergoing cardiac surgery a...
journal_title:Cardiology in the young
pub_type: 杂志文章,多中心研究
doi:10.1017/S1047951119002671
更新日期:2020-01-01 00:00:00
abstract::Disconnection of a pulmonary artery needs early surgical treatment in order to support the growth of the vessel. However, owing to the high rate of re-stenosis after traditional surgical reconstruction, we developed a hybrid approach involving the creation of pulmonary artery continuity by using autologous or heterolo...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951118001129
更新日期:2018-11-01 00:00:00
abstract::Cardiac involvement is a rare complication of infection by the influenza B virus. It usually presents with ventricular dysfunction, arrhythmias, or both. We report a 13-year-old boy with clinical, electrocardiographic, and laboratory findings of myocardial ischaemia during an otherwise silent acute infection with infl...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951105000454
更新日期:2005-04-01 00:00:00
abstract::Myocarditis is an important cause of arrhythmogenic sudden cardiac arrest in the young. A strong index of suspicion is required as not only can arrhythmias be the only clinical manifestation but also because these patients can have normal cardiac biomarkers, electrocardiographic and echocardiographic findings, and inf...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120001523
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Previous studies have demonstrated structural changes in the heart and cardiac dysfunction in foetuses with intrauterine growth restriction. There are no available data that evaluated left ventricular dimensions and mass in neonates with symmetric and asymmetric intrauterine growth restriction. Therefore, we...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113002199
更新日期:2015-02-01 00:00:00
abstract::We describe our experience with 2 patients having Costello syndrome, aged 11 and 36 months, who suffered systolic anterior motion of the aortic leaflet of the mitral valve and obstructive cardiac hypertrophy requiring surgery, comparing their cardiac characteristics to those described previously. We conclude that the ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951109991181
更新日期:2009-12-01 00:00:00
abstract:UNLABELLED:So as to determine the value of brain natriuretic peptide in the plasma as a biochemical marker for myocarditis of Kawasaki disease, we studied 69 patients. The blood samples, electrocardiograms and cross-sectional echocardiograms were obtained before the commencement of treatment and in the convalescent pha...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951102000318
更新日期:2002-03-01 00:00:00
abstract::Information about acute coronary syndrome caused by Kawasaki disease-related coronary artery lesions in adults is sketchy. We reviewed the clinical features of 50 adult patients who had an acute coronary syndrome caused by coronary artery lesions due to Kawasaki disease or probable Kawasaki disease from 1980 to 2008. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001502
更新日期:2011-02-01 00:00:00
abstract::To date, no reference values have been provided for right and left atrial filling in normal children. The aim of our study, therefore, was to characterize measurements of superior caval, hepatic, and pulmonary venous flow using Doppler echocardiography in a large group of normal children to reflect the effects of age,...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/s1047951103000283
更新日期:2003-04-01 00:00:00
abstract::Femoral vein access is the first choice for percutaneous atrial septal defect closure, and when it cannot be used due to anatomic reasons, the alternative sites should be considered, frequently increasing the complexity of the procedure. Here we report the case of a 3-year-old boy, with situs inversus and dextrocardia...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951119002099
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Identification of patients with latent rheumatic heart disease by echocardiography presents a unique opportunity to prevent disease progression. Myocardial strain is a more sensitive indicator of cardiac performance than traditional measures of systolic function. OBJECTIVE:The objective of this study was to...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951116002778
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Post-operative severe vascular stenosis and proliferating endothelial tissue lead to severe circulatory disorders and impair organ perfusion. Bioabsorbable magnesium scaffolds may help to overcome these obstructions without leaving obstructing stent material. We analyse their role in the treatment of vascula...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951120000384
更新日期:2020-04-01 00:00:00
abstract::Improvement in operative survival of patients with hypoplastic left heart syndrome has led to increasing emphasis on prevention of interstage mortality. Many centres have improved interstage results through programmes of home monitoring following discharge after the Norwood (Stage 1) operation. Experience with heighte...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951111001600
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Transcatheter closure of atrial septal defects is performed under fluoroscopy, but echocardiography has gained an important role in the procedure. With the new Amplatzer Septal Occluder a device has become available which is easy to implant with minimal fluoroscopy time. We developed an interventional proced...
journal_title:Cardiology in the young
pub_type: 临床试验,杂志文章
doi:10.1017/s1047951100008349
更新日期:1999-03-01 00:00:00
abstract::We report a case where fetal echocardiography identified both complete heart block and ventricular tachycardia. The mother tested positive for anti-Ro antibodies. Prenatal detection of this unusual combination of arrhythmias prompted early postnatal evaluation, which revealed prolongation of the QT interval. Autoimmun...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951105000673
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:SCN5A encodes sodium-channel α-subunit Nav1.5. The mutations of SCN5A can lead to hereditary cardiac arrhythmias such as the long-QT syndrome type 3 and Brugada syndrome. Here we sought to identify novel mutations in a family with arrhythmia. METHODS:Genomic DNA was isolated from blood of the proband, who w...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951117002980
更新日期:2018-05-01 00:00:00
abstract::Severe cyanosis due to pulmonary arteriovenous fistulas occurs often after a bidirectional superior cavopulmonary anastomosis (Glenn operation) and also in some congenital anomalies in which hepatic venous blood bypasses the lungs in the first passage. Relocation of hepatic flow into the lungs usually causes these fis...
journal_title:Cardiology in the young
pub_type: 杂志文章,评审
doi:10.1017/S1047951113000140
更新日期:2013-10-01 00:00:00
abstract:INTRODUCTION:Stenosis, mediated by neointimal hyperplasia and thrombosis, is a major limiting factor in successful stent implantation. The introduction of a stent, coated in its endoluminal surface by antihuman CD34 antibodies with endothelial progenitor cell-capturing properties, opens the possibility of promoting a r...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951113001376
更新日期:2014-10-01 00:00:00
abstract::It is controversial to observe or close symptomatic congenital coronary artery fistula in infants. We herein describe a medium-sized symptomatic congenital coronary artery fistula that underwent rapid spontaneous closure in an infant aged <3 months. ...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951114001127
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to see whether the open anastomosis technique using vacuum-assisted venous drainage at the time of the Fontan procedure was associated with decreased post-operative pleural effusion. METHODS:We analysed a subgroup of patients with a functional single ventricle who underwent non-fen...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951110001010
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the diagnosis, clinical features, management and post-natal follow-up in consecutive fetuses identified with tachycardia. METHODS:We reviewed consecutive fetuses with tachycardia identified in a single tertiary institution between January, 2001, and December, 2008. We considered several options f...
journal_title:Cardiology in the young
pub_type: 杂志文章
doi:10.1017/S1047951109990497
更新日期:2009-09-01 00:00:00