Abstract：
BACKGROUND AND OBJECTIVES:The aim of this paper was determine the prevalence of antibodies against Francisella tularensis in the representative sample of people from Castilla-León (Spain) before epidemic outbreak of end 1997. SUBJECTS AND METHOD:We obtain 4,825 sera (between april-1996 and april-1997) of people from Castilla-León. All sera were tested by a microagglutination technique to detect antibodies against Francisella tularensis. The positive sera were tested to determine cross-reaction with Brucella, Yersinia enterocolitica and Proteus in the tube agglutination tests. RESULTS:We detected antibodies against Francisella tularensis in 9 (0,19%) of the 4,825 sera. Only one serum from the 9 seropositive was positive in the tube agglutination against Brucella. None of the 9 sera were positive against the remaining bacterial antigen tested. CONCLUSIONS:In the people of Castilla-León before 1997 the prevalence of antibodies against Francisella tularensis was 0,19%.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Gutiérrez MP,Orduña A,Dueñas A,Bratos MA,Almaraz A,Alamo R,Rodríguez Recio MJ,Rodríguez Marcos H,Rodríguez Torres Akeywords:
subject
Has Abstractpub_date
2003-02-01 00:00:00pages
97-8issue
3eissn
0025-7753issn
1578-8989pii
S0025-7753(03)73613-6journal_volume
120pub_type
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