Abstract:
:Exercise and improved diet is known to be beneficial in the management of type 2 (non-insulin dependent) diabetes mellitus. In practice, however, it is difficult for patients to implement these changes unaided. We hypothesized that a lifestyle modification programme involving residential visits would result in beneficial effects on glycaemic control and lipid profile. Three hundred and four individuals with type 2 diabetes participated in a lifestyle modification programme, involving three residential visits (2 weeks, 1 week and one 3-day visit) spaced over 31 weeks. The subjects were all referred for treatment following repeated failure to achieve metabolic control in primary care settings. Participants received information and practical guidance regarding exercise training, nutrition, as well as stress management and psychological counselling. Clinical parameters were determined at each visit. After completion of the programme, subjects showed significant improvements in glycaemic control (P<0.0001). Oxygen uptake was significantly improved (P<0.0001) and blood pressure (P<0.0001), body mass index (P<0.0001) and serum cholesterol (P<0.001) was significantly reduced, while HDL cholesterol (P<0.05) was significantly increased. There were no changes in LDL cholesterol values. Subjects also reported increased well-being and reduced stress. In conclusion, a 31-week lifestyle modification programme results in marked improvements in glycaemic control, blood pressure and well-being in subjects with type 2 diabetes. Thus, this type of lifestyle modification programme is a powerful treatment option to reduce risk factors associated with diabetes and diabetic complications, even in patients who have not responded to conventional diabetic therapy.
journal_name
Clin Physiol Funct Imagingjournal_title
Clinical physiology and functional imagingauthors
Krook A,Holm I,Pettersson S,Wallberg-Henriksson Hdoi
10.1046/j.1475-097x.2003.00463.xkeywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
21-30issue
1eissn
1475-0961issn
1475-097Xpii
463journal_volume
23pub_type
杂志文章abstract::Previous studies have indicated that, during mechanical ventilation, an inspiratory pause enhances gas exchange. This has been attributed to prolonged time during which fresh gas of the tidal volume is present in the respiratory zone and is available for distribution in the lung periphery. The mean distribution time o...
journal_title:Clinical physiology and functional imaging
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journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章,随机对照试验
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journal_title:Clinical physiology and functional imaging
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pub_type: 杂志文章,评审
doi:10.1111/cpf.12433
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journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章
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journal_title:Clinical physiology and functional imaging
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doi:10.1111/cpf.12565
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pub_type: 杂志文章
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journal_title:Clinical physiology and functional imaging
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journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Clinical physiology and functional imaging
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