Effects of myocardial revascularization following acute coronary occlusion in pigs.

abstract：:To investigate the possible role of hepatitis C virus (HCV) in fulminant and subacute liver failure, we tested serum and liver of 13 patients undergoing orthotopic liver transplantation for the presence of HCV RNA. HCV RNA was detected in specimens from two out of eight patients negative for all viral markers with sus...

journal_title：European journal of clinical investigation

authors： Theilmann L,Solbach C,Toex U,Müller HM,Pfaff E,Otto G,Goeser T

更新日期：1992-08-01 00:00:00

abstract：:We recently reported that chloride-depletion metabolic alkalosis (CDMA) results in renal losses of Na, K, and water. In these studies we investigated whether CDMA (induced using a new model that avoids external changes in Na and water balance) was also associated with internal Na and water shifts out of the ECF. CDMA ...

journal_title：European journal of clinical investigation

authors： Garella S,Cohen JJ,Northrup TE

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Cardioprotective effects of omega-3 polyunsaturated fatty acids (n-3 PUFAs) of marine origin are well recognized. Because of the shortness of marine resources vegetable oils are increasingly used in fish farming. The effects on human health of fish fed on vegetable oils are largely unknown. METHODS:In a dou...

journal_title：European journal of clinical investigation

authors： Seierstad SL,Seljeflot I,Johansen O,Hansen R,Haugen M,Rosenlund G,Frøyland L,Arnesen H

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the significance of the development of a restrictive response to an acute saline load, defined as an increase in the ratio of peak early to peak late diastolic transmitral flow velocity (E/A ratio) associated with a decrease in the deceleration time, in patients with mild...

journal_title：European journal of clinical investigation

authors： Triposkiadis F,Moyssakis I,Makris T,Hatzizaharias A,Hadjinikolaou L,Kyriakidis M

更新日期：2001-08-01 00:00:00

abstract：:To determine the comparative value of serum Type III procollagen peptide (PIIIP) in paediatric and adult liver disease we have measured PIIIP in 201 healthy subjects (aged 1 day-77 years) and twenty-one children and five adults with chronic active hepatitis (CAH). Healthy children had significantly higher PIIIP levels...

journal_title：European journal of clinical investigation

authors： Trivedi P,Cheeseman P,Portmann B,Hegarty J,Mowat AP

更新日期：1985-04-01 00:00:00

abstract：:The biocompatibility of two commercially available charcoal columns, one containing coated and the other uncoated but immobilized charcoal, was compared during four haemoperfusions with each in eight healthy greyhounds. Reductions in arterial levels of platelets (49% and 42% respectively) and leucocytes (both 21%) wer...

journal_title：European journal of clinical investigation

authors： Weston MJ,Hanid A,Rubin MH,Langley PG,Mellon PJ,Williams R

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:A high pulse pressure (PP) is associated with adverse cardiovascular (CV) outcomes; however, this relationship may be reversed in patients with heart failure with reduced ejection fraction (HFREF). METHODS:Patients from the WARCEF trial with left ventricular ejection fraction ≤35% were included. PP was divi...

journal_title：European journal of clinical investigation

authors： Shah N,Qian M,Di Tullio MR,Graham S,Mann DL,Sacco RL,Lip GYH,Labovitz AJ,Ponikowski P,Lok DJ,Anker SD,Teerlink JR,Thompson JLP,Homma S,Freudenberger RS,WARCEF Investigators.

更新日期：2019-02-23 00:00:00

abstract：:To diagnose hypolactasia, determination of lactase enzyme activity in small intestinal biopsy material is considered to be the golden standard. Because of its strongly invasive character and the sampling problems, alternative methods have been looked for. We analysed the 13C-glucose response in serum after consumption...

journal_title：European journal of clinical investigation

authors： Vonk RJ,Stellaard F,Priebe MG,Koetse HA,Hagedoorn RE,De Bruijn S,Elzinga H,Lenoir-Wijnkoop I,Antoine JM

更新日期：2001-03-01 00:00:00

abstract：:A haemolytically inactive alpha-mobile complement C8 component was identified by crossed immunoelectrophoresis in a 27-year-old male with recurrent meningococcal infections and absence of complement mediated serum haemolytic activity. The patient's serum/plasma contained no demonstrable normal C8. C8 inhibitor activit...

journal_title：European journal of clinical investigation

authors： Brandslund I,Teisner B,Strate M,Grunnet N,Svehag SE,Isager H,Wang P

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:Experimental and clinical studies have suggested that inhibitors of the renin angiotensin system (RAS) might be useful to slow the progression of valvular calcification in patients with aortic stenosis (AS). OBJECTIVES:The aim of this study was to evaluate the relationships between the weight and tissue rem...

journal_title：European journal of clinical investigation

authors： Côté N,Couture C,Pibarot P,Després JP,Mathieu P

更新日期：2011-11-01 00:00:00

abstract：:Acute renal failure is a grave complication of systemic gram-negative sepsis. The pathophysiological mechanisms of sepsis leading to kidney injury result in part from systemic inflammatory and haemodynamic alterations. These are triggered by the interaction of endotoxin with Toll-like receptor 4 (TLR4) on cells of the...

journal_title：European journal of clinical investigation

authors： El-Achkar TM,Hosein M,Dagher PC

更新日期：2008-10-01 00:00:00

abstract：:Tumours in the adrenals originate from the adrenal cortex, the adrenal medulla or as metastases from extra-adrenal primaries. Differentiating between these three groups is the first task a pathologist has to tackle when dealing with specimens from the adrenal region. Whereas this is possible in every case with total r...

journal_title：European journal of clinical investigation

authors： Saeger W

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The pathogenesis of tumour formation in the anterior pituitary including adrenocorticotropic hormone (ACTH)-secreting tumours has been intensively studied, but the causative mechanisms involved in pituitary cell transformation and tumourigenesis remain unclear. MATERIALS AND METHODS:We searched PubMed on an...

journal_title：European journal of clinical investigation

authors： Dworakowska D,Grossman AB

更新日期：2012-06-01 00:00:00

abstract：:The concentration in serum of cathodal trypsinogen has been studied in certain clinical and experimental situations. The concentration correlated with pancreatic amylase activity. Low levels were found in patients with malabsorption due to exocrine pancreatic insufficiency. The concentration rose after endoscopic retr...

journal_title：European journal of clinical investigation

authors： Borgström A,Ohlsson K

更新日期：1978-12-01 00:00:00

abstract：BACKGROUND:Urotensin II plays a role in myocardial remodelling. Cardiac fibroblasts play a critical role in the development of cardiac fibrosis. The effect of hypoxia on urotensin II expression in cardiac fibroblasts is poorly understood. We sought to investigate the regulation of urotensin II by hypoxia in cardiac fib...

journal_title：European journal of clinical investigation

authors： Shyu KG,Wang BW,Chen WJ,Kuan P,Lin CM

更新日期：2012-01-01 00:00:00

abstract：:Currently available information on adipose tissue metabolism in man is mainly based on studies in vitro. In the present work adipose tissue lipid uptake was studied in vivo in man. 100 g glucose and 120 g milk fat with 10 microCi U-14C oleic acid were given in the overnight fasting state to eight women and 2 h after a...

journal_title：European journal of clinical investigation

authors： Mårin P,Rebuffé-Scrive M,Björntorp P

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Mortality from prostate cancer remains a significant problem with current treatment(s), with an expected 30 350 deaths from prostate cancer in 2005. Long-acting natriuretic peptide, vessel dilator, kaliuretic peptide and atrial natriuretic peptide have significant anticancer effects in breast and pancreatic ...

journal_title：European journal of clinical investigation

authors： Vesely BA,Alli AA,Song SJ,Gower WR Jr,Sanchez-Ramos J,Vesely DL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:It remains unsettled whether alcoholic cirrhosis is a risk factor for myocardial infarction (MI). METHODS:We used data from nationwide healthcare registries to study all Danes diagnosed with alcoholic cirrhosis in 1996-2014, and five controls were matched to each of them on gender and age. We excluded every...

journal_title：European journal of clinical investigation

authors： Deleuran T,Schmidt M,Vilstrup H,Jepsen P

更新日期：2020-04-01 00:00:00

abstract：:The cellular mechanisms controlling adaptive intestinal mucosal hypo- and hyperplasia are poorly understood but changes in tissue polyamine levels and in the activity of the key enzymes controlling their synthesis (ornithine decarboxylase: ODC) and degradation (diamine oxidase: DAO) have been implicated. Therefore, in...

journal_title：European journal of clinical investigation

authors： Hosomi M,Stace NH,Lirussi F,Smith SM,Murphy GM,Dowling RH

更新日期：1987-10-01 00:00:00

abstract：BACKGROUND:Cancer chemotherapy in humans based on metal complexes started at the clinical level in the late 1970s with the use of cisplatin, which forms intra-strand cross-links with DNA. METHODS:Two new platinum complexes of cis-geometry with the amino acids inosine (ino) and l-alanine (ala), Pt(ino)2Cl2 and cis-[Pt(...

journal_title：European journal of clinical investigation

authors： Charalabopoulos K,Karkabounas S,Ioachim E,Papalimneou V,Syrigos K,Evangelou A,Agnantis N,Hadjiliadis N

更新日期：2002-02-01 00:00:00

abstract：:In systemic lupus erythematosus (SLE) patients, most of the clinical manifestation share a vascular component triggered by endothelial dysfunction. Endothelial cells (ECs) activation occurs both on the arterial and venous side, and the high vascular density of kidneys accounts for the detrimental outcomes of SLE throu...

journal_title：European journal of clinical investigation

authors： Mancardi D,Arrigo E,Cozzi M,Cecchi I,Radin M,Fenoglio R,Roccatello D,Sciascia S

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Kinetic abnormalities of apolipoprotein B (apoB)-containing lipoproteins in noninsulin-dependent diabetes mellitus (NIDDM) remain poorly understood. To get further insight into these abnormalities we performed a stable isotope kinetic experiment comparing the metabolism of apoB-containing lipoproteins in mod...

journal_title：European journal of clinical investigation

authors： Duvillard L,Pont F,Florentin E,Galland-Jos C,Gambert P,Vergès B

更新日期：2000-08-01 00:00:00

abstract：:The capillary permeability in human skeletal muscle, expressed as capillary diffusion capacity (CDC) for 51Cr-EDTA, was determined during exercise with a local clearance method in two groups of healthy male subjects: a younger group with a mean age of 30 years and an older one with a mean age of 58 years. The main fin...

journal_title：European journal of clinical investigation

authors： Berglund B,Efendić S,Strandell T,Luft R

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Bezafibrate reportedly lowers serum lipids and plasma fibrinogen in humans and rats, but the mechanism of this process has still to be clarified. We have addressed this problem by investigating the effects of bezafibrate on fibrinogen in the human hepatoma HepG2 cell line. METHODS:In cells cultured with and...

journal_title：European journal of clinical investigation

authors： Binsack R,Stegmeier K,Dörge L,Völkl A

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Thyroid feedback regulation and equilibria between thyroid hormones differ in the presence or absence of a functioning thyroid remnant. MATERIALS AND METHODS:This study examines the relationship between the sensitivity of TSH feedback and thyroid capacity in untreated patients with thyroid autoimmune diseas...

journal_title：European journal of clinical investigation

authors： Hoermann R,Midgley JEM,Larisch R,Dietrich JW

更新日期：2018-10-01 00:00:00

abstract：:The collagenolytic activities were assayed in fibroblast cultures established from ten keratoconus and six control corneal explants. The assays included those for both type I and type IV collagenase. The amount of free, directly assayable type I collagenase was highly increased in the media of keratoconus primary cell...

journal_title：European journal of clinical investigation

authors： Ihalainen A,Salo T,Forsius H,Peltonen L

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Excess of cardiovascular risk among patients with chronic inflammatory diseases has been attributed to increased arterial stiffness. Hypercholesterolaemia has been demonstrated to promote a low-grade inflammatory status. The objective of the present study was to define, in hypercholesterolaemia, the influenc...

journal_title：European journal of clinical investigation

authors： Pirro M,Schillaci G,Savarese G,Gemelli F,Vaudo G,Siepi D,Bagaglia F,Mannarino E

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Advanced glycation end-products (AGEs) are increased in situations with hyperglycemia and oxidative stress such as diabetes mellitus. They are products of nonenzymatic glycation and oxidation of proteins and lipids. The kidney plays an important role in clearance and metabolism of AGEs. METHODS:Medline and ...

journal_title：European journal of clinical investigation

authors： Busch M,Franke S,Rüster C,Wolf G

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND/AIMS:Nitric oxide synthase (NOS) 3-deficient (NOS-3 KO) mice have an increased systemic arterial pressure but develop portal hypertension to the same extent as wildtype (WT) mice. We hypothesized that other vasodilators in the portal circulation compensate for the lack in NOS-3 activity. We used quantitative...

journal_title：European journal of clinical investigation

authors： Biecker E,Sägesser H,Reichen J

更新日期：2004-04-01 00:00:00

abstract：:SS-R and SS have been demonstrated in non-pathological and pathological lymphoid tissue and may play a regulatory, mostly inhibitory, role in the immune response. SS is produced by lymphocytes and monocytes which suggests an autocrine or paracrine regulatory role, but SS may be released as well by nerve endings. It ca...

journal_title：European journal of clinical investigation

authors： van Hagen PM,Krenning EP,Kwekkeboom DJ,Reubi JC,Anker-Lugtenburg PJ,Löwenberg B,Lamberts SW

更新日期：1994-02-01 00:00:00