Abstract：
:Mbl is a bacterial actin homolog that controls cell morphogenesis in Bacillus subtilis. A functional GFP-Mbl fusion protein was used to examine the behavior of the helical cables formed by Mbl protein in live B. subtilis cells. The cables undergo dynamic changes during cell cycle progression. They are stable but not rigid while elongating in parallel with cell growth, and they require septum formation to divide/cleave. Fluorescence recovery after photobleaching (FRAP) analysis showed that the cables are continuously remodeled during cell elongation. Turnover occurs along the length of the helical Mbl filaments, with no obvious polarity and a recovery half-time of about 8 min. These findings have important implications for the nature of bacterial cell wall architecture and synthesis.
journal_name
Dev Celljournal_title
Developmental cellauthors
Carballido-López R,Errington Jdoi
10.1016/s1534-5807(02)00403-3keywords:
subject
Has Abstractpub_date
2003-01-01 00:00:00pages
19-28issue
1eissn
1534-5807issn
1878-1551pii
S1534-5807(02)00403-3journal_volume
4pub_type
杂志文章abstract：:Blood vessels form an important interface between the environment and the organism by carrying oxygen and nutrients to all cells and thus determining cellular metabolism. It is therefore not surprising that oxygen and metabolism influence the development of the vascular network. Here, we discuss recent insights regard...
journal_title：Developmental cell
pub_type： 杂志文章,评审
doi：10.1016/j.devcel.2009.01.003
更新日期：2009-02-01 00:00:00
abstract：:The mechanism responsible for subdividing the embryo into individual tissues is a fundamental, yet still poorly understood, question in developmental biology. Various general hypotheses have been proposed, involving differences in cell adhesion, contractility, or contact-mediated repulsion. However, the key parameter ...
journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2013.09.004
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abstract：:Novel body structures are often generated by the redeployment of ancestral components of the genome. In this issue of Developmental Cell, Glassford et al. (2015) present a thorough analysis of the co-option of a gene regulatory network in the origin of an evolutionary novelty. ...
journal_title：Developmental cell
pub_type： 评论,杂志文章
doi：10.1016/j.devcel.2015.08.022
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abstract：:The ability of the death ligand TRAIL to induce tumor cell apoptosis has led to the development of TRAIL-based cancer therapies. Reporting recently in Molecular Cell, Lu et al. (2014) show that the basis for differential TRAIL responses involves clustering of death receptor complexes by E-cadherin and the actin cytosk...
journal_title：Developmental cell
pub_type： 评论,杂志文章
doi：10.1016/j.devcel.2014.06.031
更新日期：2014-07-14 00:00:00
abstract：:Cell competition promotes the elimination of weaker cells from a growing population. Here we investigate how cells of Drosophila wing imaginal discs distinguish "winners" from "losers" during cell competition. Using genomic and functional assays, we have identified several factors implicated in the process, including ...
journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2010.05.010
更新日期：2010-06-15 00:00:00
abstract：:How metabolism is rewired during embryonic development is still largely unknown, as it remains a major technical challenge to resolve metabolic activities or metabolite levels with spatiotemporal resolution. Here, we investigated metabolic changes during development of organogenesis-stage mouse embryos, focusing on th...
journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2017.01.015
更新日期：2017-02-27 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
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更新日期：2004-02-01 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2015.04.022
更新日期：2015-06-22 00:00:00
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journal_title：Developmental cell
pub_type： 评论,杂志文章
doi：10.1016/j.devcel.2004.07.014
更新日期：2004-08-01 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章,评审
doi：10.1016/j.devcel.2017.02.018
更新日期：2017-05-22 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2014.11.005
更新日期：2014-12-08 00:00:00
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journal_title：Developmental cell
pub_type： 评论,杂志文章
doi：10.1016/j.devcel.2008.10.010
更新日期：2008-11-01 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2016.05.006
更新日期：2016-06-06 00:00:00
abstract：:Macropinocytosis coordinates non-specific uptake of macromolecules and fluid. Cancers employ macropinocytosis to obtain nutrients to support their metabolic homeostasis. In this issue of Developmental Cell, Lee et al. (2019) report that glutamine deprivation boosts macropinocytosis via EGFR signaling induction, provid...
journal_title：Developmental cell
pub_type： 评论,杂志文章
doi：10.1016/j.devcel.2019.07.020
更新日期：2019-08-05 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2012.01.002
更新日期：2012-04-17 00:00:00
abstract：:Tissues have a natural capacity to replace dying cells and to heal wounds. This ability resides in resident stem cells, which self-renew, preserve, and repair their tissue during homeostasis and following injury. The skin epidermis and its appendages are subjected to daily assaults from the external environment. A hig...
journal_title：Developmental cell
pub_type： 杂志文章,评审
doi：10.1016/j.devcel.2017.10.001
更新日期：2017-11-20 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2014.09.009
更新日期：2014-11-24 00:00:00
abstract：:We have used Drosophila ovarian follicle stem cells (FSCs) to study how stem cells are regulated by external signals and draw three main conclusions. First, the spatial definition of supportive niche positions for FSCs depends on gradients of Hh and JAK-STAT pathway ligands, which emanate from opposite, distant sites....
journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2012.09.010
更新日期：2012-10-16 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2018.08.011
更新日期：2018-10-08 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
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journal_title：Developmental cell
pub_type： 杂志文章
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journal_title：Developmental cell
pub_type： 杂志文章,评审
doi：10.1016/j.devcel.2017.08.015
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journal_title：Developmental cell
pub_type： 杂志文章
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更新日期：2017-12-04 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2018.08.008
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journal_title：Developmental cell
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2008.01.005
更新日期：2008-03-01 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2017.08.014
更新日期：2017-10-09 00:00:00
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journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2012.12.015
更新日期：2013-02-11 00:00:00
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journal_title：Developmental cell
pub_type： 评论,杂志文章
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更新日期：2012-02-14 00:00:00
abstract：:A balance between Six2-dependent self-renewal and canonical Wnt signaling-directed commitment regulates mammalian nephrogenesis. Intersectional studies using chromatin immunoprecipitation and transcriptional profiling identified direct target genes shared by each pathway within nephron progenitors. Wnt4 and Fgf8 are e...
journal_title：Developmental cell
pub_type： 杂志文章
doi：10.1016/j.devcel.2012.07.008
更新日期：2012-09-11 00:00:00
