The effects of aging on the eruptive behavior of the mandibular incisor in male rats.

abstract：:The relationship between structural changes and hyaluronic acid (HA) content in muscular atrophy is unknown. The objective of our study was to conduct multifaceted evaluations of the change in muscle extensibility in muscular atrophy, in terms of morphological aspects as well as from a biochemical viewpoint, including...

journal_title：Connective tissue research

authors： Ishikawa T,Shimizu M,Mikawa Y,Zhu BL,Quan L,Li DR,Zhao D,Maeda H

更新日期：2005-01-01 00:00:00

abstract：:Although fibronectin (FN) modified by advanced glycation end products (AGEs) has been shown to contribute to the development of diabetic vascular complications through its reduced adhesive activity to vascular cells, little is known about changes in the cell binding domain of AGE-modified FN. Here we examined the mech...

journal_title：Connective tissue research

authors： Sakata N,Sasatomi Y,Meng J,Ando S,Uesugi N,Takebayashi S,Nagai R,Horiuchi S

更新日期：2000-01-01 00:00:00

abstract：:The effect of intra-bone injection of differentiated rat bone marrow mesenchymal stem cells (BMMSCs) into the femur of osteoporotic female rats was studied. Osteoporosis was induced in Wistar female rats by bilateral ovariectomy. Then, 0.75 million BMMSCs isolated from healthy rats were injected into the femurs of ost...

journal_title：Connective tissue research

authors： Ocarino Nde M,Boeloni JN,Jorgetti V,Gomes DA,Goes AM,Serakides R

更新日期：2010-12-01 00:00:00

abstract：:Collagen type I fiber-based scaffolds for anterior cruciate ligament (ACL) replacement were evaluated for their mechanical properties and their ability to promote cellular proliferation. Prior to scaffold formation, two crosslinking methods were investigated on individual reconstituted collagen type I fibers, ultravio...

journal_title：Connective tissue research

authors： Walters VI,Kwansa AL,Freeman JW

更新日期：2012-01-01 00:00:00

abstract：:The effects of two forms of elastase on the Young's Modulus of elastic tissue have been studied. The monomeric, calcium poor form of the enzyme lowers the value of the Young's Modulus before an appreciable amount of protein is taken into solution. The polymeric, calcium rich enzyme on the other hand degrades the prote...

journal_title：Connective tissue research

authors： Hall DA

更新日期：1976-01-01 00:00:00

abstract：:Glycosaminoglycan synthesis by cells cultured from nodule or band tissues of patients with Dupuytren's disease was compared with that of skin fibroblasts cultured from uninvolved areas of the palm. No differences were observed in culture which could account either for the abnormal glycosaminoglycan content or the incr...

journal_title：Connective tissue research

authors： Slack C,Flint MH,Thompson BM

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:Experimental measurements of bone mineral density distributions (BMDDs) enable a determination of secondary mineralization kinetics in bone, but the maximum degree of mineralization and how this maximum is approached remain uncertain. We thus test computationally different hypotheses on late stages of bone mine...

journal_title：Connective tissue research

authors： Buenzli PR,Lerebours C,Roschger A,Roschger P,Weinkamer R

更新日期：2018-12-01 00:00:00

abstract：:Conditions were established to stimulate human gingival fibroblast explant cultures to synthesize milligram quantities of the metalloproteinase proenzymes, prostromelysin and procollagenase. To stimulate enzyme production, cells were treated with 1 nM recombinant human IL-1 beta for approximately 7 days under serum fr...

journal_title：Connective tissue research

authors： Lark MW,Walakovits LA,Shah TK,Vanmiddlesworth J,Cameron PM,Lin TY

更新日期：1990-01-01 00:00:00

abstract：:Multiple hereditary exostoses (MHE) is an autosomal dominant disorder that affects about 1 in 50,000 children worldwide. MHE, also known as hereditary multiple exostoses (HME) or multiple osteochondromas (MO), is characterized by cartilage-capped outgrowths called osteochondromas that develop adjacent to the growth pl...

journal_title：Connective tissue research

authors： Phan AQ,Pacifici M,Esko JD

更新日期：2018-01-01 00:00:00

abstract：:Elastic ear cartilage and aortae from nine-day-old hamsters were incubated in Krebs-Ringer medium containing ascorbate, beta-aminopropionitrile and either [14C]proline or [3H]valine. The [14C]proline-labeled proteins were separated by chromatography on Agarose A-5 m in sodium dodecyl sulfate and their [14C]-hydroxypro...

journal_title：Connective tissue research

authors： Heeger P,Rosenbloom J

更新日期：1980-01-01 00:00:00

abstract：:Purpose: In experimental models of equine joint-injury and osteoarthritis synovial fluid (SF) composition (proteoglycan-4, hyaluronan) can vary, along with changes to SF mechanical function (lubrication, viscosity). The study hypotheses were a) clinical equine joint-injury and disease results in altered SF composition...

journal_title：Connective tissue research

authors： Matheson A,Regmi SC,Martin-Alarcon L,Jay GD,Scott WM,Schmidt TA

更新日期：2020-04-20 00:00:00

abstract：:The meniscal cartilages in the knee function to improve congruity of the medial and lateral femoro-tibial joints and play critical roles in load distribution and joint stability. Meniscal tears of various configurations are one of the most common conditions of the knee and are associated with an increased risk of deve...

journal_title：Connective tissue research

authors： Melrose J,Fuller ES,Little CB

更新日期：2017-01-01 00:00:00

abstract：:Hall type voltage has been observed in bone and its two major components (collagen and apatite) in the region of moderately high electric and magnetic fields. The configuration of the sample placement and the experimental set up was the same as that adopted in standard Hall measurements. The resistivity of the sample ...

journal_title：Connective tissue research

authors： Behari J,Andrabi WH

更新日期：1978-01-01 00:00:00

abstract：:Alveolar mucosa and attached gingiva are two continuous but functionally distinct connective tissues covering alveolar bone of the jaw. In this study, the major matrix component of these tissues, collagen, was biochemically characterized and compared. The tissues were obtained from mature pigs and analyzed for collage...

journal_title：Connective tissue research

authors： Katafuchi M,Matsuura T,Atsawasuwan P,Sato H,Yamauchi M

更新日期：2007-01-01 00:00:00

abstract：:In the early mineralized enamel crystals, ribbon-like crystals appear near the ameloblasts. Some ribbon-like crystals showed helical or spiral structure within restricted environment during the preparation of embryonic bovine specimens for electron microscope. These specimens did not suffer from the cutting damages no...

journal_title：Connective tissue research

authors： Suzuki K,Sakae T,Kozawa Y

更新日期：1998-01-01 00:00:00

abstract：:Aseptic loosening remains the primary cause of failure in total joint arthroplasty. Implant-derived particles are thought to be a main cause of osteolysis that leads to the failure. Substance P (SP) immunoreactive nerve fibers have been detected in the periprosthetic membrane of aseptic loose hip prostheses. We isolat...

journal_title：Connective tissue research

authors： Qian Y,Zhang XL,Zeng BF,Jiang Y,Shen H,Wang Q

更新日期：2013-01-01 00:00:00

abstract：:An immunohistochemical analysis of the eggshell membranes shows the occurrence of type X collagen while type I collagen was not detected by using an appropriate monoclonal antibody with untreated shell membranes. A positive immuno-reaction for type I collagen was obtained after digestion of the shell membranes with pe...

journal_title：Connective tissue research

authors： Arias JL,Fernandez MS,Dennis JE,Caplan AI

更新日期：1991-01-01 00:00:00

abstract：:Bone sialoprotein (BSP) expression is restricted to cells associated with the mineralization of bones and teeth. We previously identified a homeodomain binding element in a 2.5 kb fragment of the murine Bsp promoter that is required for osteoblast-selective expression in cell culture. To examine the role of this eleme...

journal_title：Connective tissue research

authors： Gopalakrishnan R,Thomas PE,Benson MD,Wang D,Franceschi RT

更新日期：2003-01-01 00:00:00

abstract：:Monoclonal antibodies (mAbs) (4F2 and 7E12) were prepared against heparan sulfate proteoglycan (HSPG) isolated from bovine glomeruli. Enzyme linked immunosorbent assays (ELISA) and immunoblotting demonstrated that the mABs reacted with HSPG. Indirect immunofluorescence (IF) showed that the mAbs stained renal basement ...

journal_title：Connective tissue research

authors： Kemeny E,Fillit HM,Damle S,Mahabir R,Kefalides NA,Gregory JD,Antonovych T,Sabnis S,Zabriskie JB

更新日期：1988-01-01 00:00:00

abstract：:A partially purified BMP preparation was combined with a fibrous glass membrane (FGM) or porous particles of hydroxyapatite (PPHAP), and then implanted subcutaneously into the backs of rats. As a control of these new carriers, a conventional carrier of insoluble bone matrix (IBM) was also used. These new geometrically...

journal_title：Connective tissue research

authors： Kuboki Y,Saito T,Murata M,Takita H,Mizuno M,Inoue M,Nagai N,Poole AR

更新日期：1995-01-01 00:00:00

abstract：:The small leucine-rich repeat proteoglycans (SLRPs) constitute a group of structurally and functionally related molecules that participate in the organization of the extracellular matrix ECM and have important effects on cell behavior. Osteosarcomas are heterogeneous bone tumors whose common characteristic is the prod...

journal_title：Connective tissue research

authors： Nikitovic D,Berdiaki K,Chalkiadaki G,Karamanos N,Tzanakakis G

更新日期：2008-01-01 00:00:00

abstract：:Bone sialoprotein (BSP) and osteopontin (OPN) are two extracellular bone matrix proteins that have the ability to modulate the growth of hydroxyapatite in vitro. Studies of BSP/OPN hydroxyapatite interactions in the past have been directed toward the identification of essential structural elements that allow these two...

journal_title：Connective tissue research

authors： Stubbs JT 3rd

更新日期：1996-01-01 00:00:00

abstract：:Human skin fibroblasts cultured with 4-methylumbelliferone (MU), a hyaluronan synthesis inhibitor, produce a hyaluronan-deficient extracellular matrix (See [9]). Our present study investigated the effects of MU on proteoglycan, which is the other main component of the extracellular matrix, and interacts with hyalurona...

journal_title：Connective tissue research

authors： Funahashi M,Nakamura T,Kakizaki I,Mizunuma H,Endo M

更新日期：2009-01-01 00:00:00

abstract：:The basic subunit of cartilage proteoglycan consists of multiple glycosaminoglycan chains covalently attached to a core protein. It is unclear as to whether there is a single core protein or multiple different core proteins, since previous studies using either chondroitinase or testicular hyaluronidase to enzymaticall...

journal_title：Connective tissue research

authors： Keiser HD,Hatcher VB

更新日期：1977-01-01 00:00:00

abstract：:Radiation therapy is one of the routine treatment modalities for cancer patients. Ionizing radiation (IR) can induce bone loss, and consequently increases the risk of fractures with delayed and nonunion of the bone in the cancer patients who receive radiotherapy. The orchestrated bone remodeling can be disrupted due t...

journal_title：Connective tissue research

authors： Zhang J,Qiu X,Xi K,Hu W,Pei H,Nie J,Wang Z,Ding J,Shang P,Li B,Zhou G

更新日期：2018-11-01 00:00:00

abstract：:TGF beta modulates the growth and differentiation of various cell types, in part by regulating the production of extracellular matrix proteins. In rat osteoblast-like cells TGF beta stimulates the production of collagen, osteopontin and osteonectin. On the other hand, TGF beta inhibits the production of osteocalcin, o...

journal_title：Connective tissue research

authors： Noda M,Rodan GA

更新日期：1989-01-01 00:00:00

abstract：:Human aortic smooth muscle cells (AoSMCs) change their extracellular matrix composition during aging, with direct effects on cellular events and cell migration. For example, active matrix metalloproteinase-2 (MMP-2) is synthesized only by young AoSMCs, whereas aged cells produce only the inactive zymogen form. The pro...

journal_title：Connective tissue research

authors： Vigetti D,Moretto P,Viola M,Genasetti A,Rizzi M,Karousou E,Clerici M,Bartolini B,Pallotti F,De Luca G,Passi A

更新日期：2008-01-01 00:00:00

abstract：:Transforming growth factor beta (TGF-beta) is a ubiquitous regulator of cellular growth and differentiation. The present study investigated the effects of TGF-beta on chick growth plate chondrocyte proliferation, matrix synthesis, and alkaline phosphatase activity in short term cultures. TGF-beta markedly stimulated D...

journal_title：Connective tissue research

authors： Rosier RN,O'Keefe RJ,Crabb ID,Puzas JE

更新日期：1989-01-01 00:00:00

abstract：:The novel method of high voltage electron microscopic tomography (3D) has been applied for the first time to examine ultrastructural features and spatial relations between collagen fibrils and mineral crystals in a mouse mutant (oim/oim) which replicates a moderate to severe form of osteogenesis imperfecta. The animal...

journal_title：Connective tissue research

authors： Landis WJ

更新日期：1995-01-01 00:00:00

abstract：:Syndecan-4 is emerging as an important player in cell interaction with the extracellular environment and has been shown to be involved in the progression of intervertebral disc degeneration. However, the mechanism of syndecan-4 regulation by TNF-α and the role of TGF-β1 in regulating syndecan-4 expression remain poorl...

journal_title：Connective tissue research

authors： Yang H,Liu H,Li X,Pan H,Li Z,Wang J,Zheng Z

更新日期：2015-01-01 00:00:00