Abstract:
STUDY DESIGN:A retrospective review of 20 patients undergoing circumferential lumbar fusion with coralline hydroxyapatite blocks anteriorly and autograft with transpedicular or translaminar facet screw fixation posteriorly. OBJECTIVES:To examine the efficacy of coralline hydroxyapatite as a bone graft substitute for anterior lumbar interbody fusion. SUMMARY OF BACKGROUND DATA:Autograft is the gold standard for bone grafting in the anterior lumbar spine. Harvesting bone from the iliac crest leads to significant postoperative pain and morbidity. Femoral ring allograft is a widely used alternative to autograft but has some inherent problems. Coralline hydroxyapatite was shown to be 100% successful for anterior cervical fusion when combined with rigid plating. METHODS:A retrospective review of 20 patients with low back pain and indicated for surgical intervention. A circumferential instrumented fusion was performed with coralline hydroxyapatite blocks anteriorly and transpedicular or translaminar facet fixation and autograft posteriorly. All patients reached a minimum 3-year clinical and radiologic follow-up. RESULTS:Radiographic follow-up yielded a solid arthrodesis rate of 93.8% by level (30 of 32 disc spaces) and 90% by patient (18 of 20). Clinical follow-up generated a mean pain reduction of 61.8% with clinical success demonstrated in 80% (16 of 20) of all patients who reported good or excellent pain relief. Eight of 12 (66.7%) patients employed before surgery returned to work in some capacity. CONCLUSIONS:Coralline hydroxyapatite is a practicable anterior lumbar interbody fusion alternative to autograft and allograft as part of a circumferential fusion with rigid posterior fixation. It is not recommended for stand-alone anterior lumbar interbody fusion without further study.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Thalgott JS,Klezl Z,Timlin M,Giuffre JMdoi
10.1097/00007632-200212150-00011keywords:
subject
Has Abstractpub_date
2002-12-15 00:00:00pages
E518-25; discussion E526-7issue
24eissn
0362-2436issn
1528-1159journal_volume
27pub_type
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