Abstract:
INTRODUCTION:Thrombosis of the hepatic artery following orthotopic liver transplantation (OLT) can be a devastating com-plication impacting on recipient outcome. The utility of routine intraoperative flow measurements of the hepatic artery in predicting subsequent hepatic artery thrombosis (HAT) is presented in this study. METHODS:Data on all adult OLT recipients between July 1995 and May 2000 were analysed. This included the routine intra-operative flow measurements of both the hepatic artery and portal vein using a Doppler flow meter. RESULTS:Thirteen out of 198 (6.6%) instances of OLT were complicated by HAT. The mean and median flow rates of the hepatic artery in the OLT with HAT were 262 mL/min and 220 mL/min, respectively. These were significantly lower than the respective values of 436 mL/min and 400 mL/min in the OLT without HAT (P = 0.0036). This was independent of recipient age, sex, weight and intraoperative portal flow rates. However there was extensive overlap for the intraoperative hepatic artery flow rates obtained between the HAT and non-HAT groups. The risk of HAT was increased by a factor of 6 if the intraoperative hepatic artery flow rate was less than 200 mL/min. The average allograft survival was significantly lower in the HAT group at 373 days vs the non-HAT group at 763 days (P = 0.026). CONCLUSION:The routine use of intraoperative flow measurements of the hepatic artery may be a useful adjunct in identifying the hepatic artery reconstruction, which is at risk of subsequent HAT.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Lin M,Crawford M,Fisher J,Hitos K,Verran Ddoi
10.1046/j.1445-2197.2002.02552.xkeywords:
subject
Has Abstractpub_date
2002-11-01 00:00:00pages
798-800issue
11eissn
1445-1433issn
1445-2197pii
2552journal_volume
72pub_type
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