Atopic diseases of childhood.

abstract：PURPOSE OF REVIEW:Neurodevelopmental-behavioural paediatrics (NBP) is a field of medical practice that has arisen in response to recent changes in child health epidemiology. This review considers how the profession of NBP is addressing clinical need, and discusses possibilities for future development of the field. REC...

journal_title：Current opinion in pediatrics

authors： McDowell M,Lesslie J

更新日期：2019-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Altered epigenetics is central to oncogenesis in many pediatric cancers. Aberrant epigenetic states are induced by mutations in histones or epigenetic regulatory genes, aberrant expression of genes regulating chromatin complexes, altered DNA methylation patterns, or dysregulated expression of noncodin...

journal_title：Current opinion in pediatrics

authors： Panditharatna E,Filbin MG

更新日期：2020-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Continuous glucose monitoring (CGM) is increasingly used in the management of diabetes in children and adults, but there are few data regarding its use in neonates. The purpose of this article is to discuss the potential benefits and limitations of CGM in neonates. RECENT FINDINGS:Smaller electrodes ...

journal_title：Current opinion in pediatrics

authors： Shah R,McKinlay CJD,Harding JE

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Selective mutism is a disorder in which an individual fails to speak in certain social situations though speaks normally in other settings. Most commonly, this disorder initially manifests when children fail to speak in school. Selective mutism results in significant social and academic impairment in ...

journal_title：Current opinion in pediatrics

authors： Hua A,Major N

更新日期：2016-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Epidermolysis bullosa is a hereditary skin disorder characterized by skin fragility. However, the disease can manifest in many different organ systems, therefore children born with epidermolysis bullosa may have life long, complex medical needs. In this review, we will use a system-based approach to h...

journal_title：Current opinion in pediatrics

authors： Cohn HI,Teng JM

更新日期：2016-08-01 00:00:00

abstract：:A number of growth factors have been identified that participate in lung growth and repair. The early stages of the repair cascade are important in preventing the later development of fibrosis. Both transforming growth factor-beta and basic fibroblast growth factor can have beneficial effects when given early in some ...

journal_title：Current opinion in pediatrics

authors： Perkett EA

更新日期：1995-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Nonaccidental trauma and neglect continue to be major problems for children, families, and the providers who care for them. Whereas prevention is the key to ending child abuse and neglect, diagnosis and treatment continue to be the mainstays of practice. This article will briefly review the epidemiolo...

journal_title：Current opinion in pediatrics

authors： Tenney-Soeiro R,Wilson C

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Pediatric-onset multiple sclerosis (MS) is increasingly recognized. Conversely, MS diagnosis in the pediatric population continues to be challenging, particularly in the youngest group of patients. An interesting amount of data has been recently published concerning immunopathogenesis, environmental f...

journal_title：Current opinion in pediatrics

authors： Tenembaum SN

更新日期：2010-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Osteogenic sarcoma, also known as osteosarcoma, is a primary malignancy of the bone in which spindle cells produce osteoid. Although rare in the general population, these tumors are the most common primary malignancies of bone and the fifth most common primary malignancy of adolescence. This paper aim...

journal_title：Current opinion in pediatrics

authors： Kim HJ,Chalmers PN,Morris CD

更新日期：2010-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe current concepts on inflammation, immunity and insulin resistance. Metabolic and immune systems are closely involved in inflammation and significantly contribute to the pathology seen in the pediatric intensive care unit. The ability of insulin to decrease hep...

journal_title：Current opinion in pediatrics

authors： Dhar A,Castillo L

更新日期：2011-06-01 00:00:00

abstract：:A constant in the practice of general pediatrics is an emphasis on infant nutrition and monitoring of growth. These topics are the focus of this issue's "Office pediatrics" section. Much of the new research and publication concerning nutrition in childhood in the past year continues to focus on breastfeeding-its short...

journal_title：Current opinion in pediatrics

authors： Rider E,Samuels R,Wilson K,Homer C

更新日期：1996-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews the importance of appropriate developmental surveillance in early childhood, what is known about its effectiveness in current pediatric practice, and ways in which its delivery can be improved to optimize child outcomes. RECENT FINDINGS:Many infants and young children with develo...

journal_title：Current opinion in pediatrics

authors： King TM,Glascoe FP

更新日期：2003-12-01 00:00:00

abstract：:Two toddlers presented to their primary medical providers with anasarca and severe anemia. Laboratory evaluation revealed iron deficiency along with hypoproteinemia and hypoalbuminemia. Both children were diagnosed with iron deficiency anemia and were suspected to have an associated protein-losing enteropathy. A brief...

journal_title：Current opinion in pediatrics

authors： Salstrom JL,Kent M,Liang X,Wang M

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Dyskeratosis congenita, a rare condition characterized by mucocutaneous abnormalities and bone marrow failure, is caused by inherited defects in the telomerase complex. Autosomal dominant dyskeratosis congenita is associated with mutations in the RNA component of telomerase, hTERC, while X-linked dysk...

journal_title：Current opinion in pediatrics

authors： Bessler M,Wilson DB,Mason PJ

更新日期：2004-02-01 00:00:00

abstract：:Smoking prevention during childhood and adolescence is critical to the successful reduction of tobacco-related morbidity and mortality in the United States. The research literature is replete with surveys describing youth smoking acquisition and related factors. In addition to its direct harm, tobacco use may be a gat...

journal_title：Current opinion in pediatrics

authors： Sockrider MM

更新日期：1997-06-01 00:00:00

abstract：:The insulin-like growht factors (IGFs) are potent mitogenic agents that have been recognized for three decades. Recently, however, the complex milieu in which they operate has begun to be unraveled. Endocrine and autocrine patterns of IGF secretion have been identified and specific receptors that bind IGFs and mediate...

journal_title：Current opinion in pediatrics

authors： Cohen P,Rosenfeld RG

更新日期：1994-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The small bowel has been a technically difficult area to examine. Indirect modalities such as barium follow-through have the disadvantage of attendant radiation exposure. Capsule endoscopy, a novel wireless method of investigation of the small bowel, has acquired an important role in both adult and pa...

journal_title：Current opinion in pediatrics

authors： Sidhu R,McAlindon ME,Sanders DS,Thomson M

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Infantile spasms, mental retardation, autism, and dystonia represent disabling diseases for which little etiologic information is available. Mutations in the Aristaless related homeobox gene (ARX) have been found in patients with these conditions. This discovery provides important genetic information ...

journal_title：Current opinion in pediatrics

authors： Sherr EH

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to explore the effects of the opioid crisis on pediatric patients in the postoperative setting and provide recommendations for well-tolerated opioid prescribing practices. RECENT FINDINGS:Opioid overdoses have increased among all age groups, predominantly related to over...

journal_title：Current opinion in pediatrics

authors： Harbaugh CM,Gadepalli SK

更新日期：2019-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Describe developments in the etiological understanding of Tourette syndrome. RECENT FINDINGS:Tourette syndrome is a complex heterogenous clinical syndrome, which is not a unitary entity. Pathophysiological models describe gamma-aminobutyric acid-ergic-associated disinhibition of cortico-basal ganglia...

journal_title：Current opinion in pediatrics

authors： Dale RC

更新日期：2017-12-01 00:00:00

abstract：:Dietary long-chain polyunsaturated fatty acids have demonstrable beneficial effects on early development. The effects on neural development are of particular interest. Human milk is the best and only time-proven source of fat and essential fatty acids in the infant diet. Technologic procedures based on chemical and ph...

journal_title：Current opinion in pediatrics

authors： Uauy R,Mena P

更新日期：1999-04-01 00:00:00

abstract：:Cerebral palsy is caused by a static lesion to the cerebral motor cortex that is acquired before, at, or within 5 years of birth. Multiple causes for the condition exist and include cerebral anoxia, cerebral hemorrhage, infection, and genetic syndromes. Cerebral palsy is commonly classified according to the type of mo...

journal_title：Current opinion in pediatrics

authors： Dabney KW,Lipton GE,Miller F

更新日期：1997-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The clinical importance of overgrowth syndromes in the pediatric patient population has been increasingly recognized during the past decade, but clinical overlap among overgrowth syndromes often makes diagnostic categorization difficult. Advances in the molecular delineation of overgrowth syndromes in...

journal_title：Current opinion in pediatrics

authors： Cytrynbaum CS,Smith AC,Rubin T,Weksberg R

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The current review addresses the importance of the prospective cohort design in large, unselected populations starting early in life for understanding the origins of childhood health disorders. RECENT FINDINGS:Cohort studies originating in healthy populations have contributed to great advances in hea...

journal_title：Current opinion in pediatrics

authors： Paneth N,Monk C

更新日期：2018-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Simulation has been widely adopted as a training and assessment tool in medical education. Conventional teaching methods may be inadequate to properly train healthcare providers for rare but potentially lethal events in pediatrics such as trauma and respiratory arrest. Recent studies suggest pediatric...

journal_title：Current opinion in pediatrics

authors： Weinberg ER,Auerbach MA,Shah NB

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review examines neonatal bacterial skin infections with respect to host immunity, bacterial pathogens, patterns of infection, and new therapeutic approaches. RECENT FINDINGS:Advances have been made in our understanding of innate host defense and the emerging role of cutaneous antimicrobial pepti...

journal_title：Current opinion in pediatrics

authors： Larson AA,Dinulos JG

更新日期：2005-08-01 00:00:00

abstract：:von Willebrand disease (VWD) is a bleeding disorder caused by quantitative (type 1 and 3) or qualitative (type 2) defects of von Willebrand factor (VWF). The mechanisms of most inherited VWD types have been recently elucidated by genetic and molecular diagnosis, but the phenotypic tests based on measurements of plasma...

journal_title：Current opinion in pediatrics

authors： Federici AB,Mannucci PM

更新日期：2002-02-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview of the pathogenesis of pulmonary edema and describe recent discoveries related to the clearance of airspace fluid and potential new therapies for this life-threatening disorder. RECENT FINDINGS:It is clinically important to determine the mechanisms responsible for the clearance...

journal_title：Current opinion in pediatrics

authors： O'Brodovich H

更新日期：2005-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current work investigating the neural bases of autism spectrum disorder (ASD) within the discipline of electrophysiological brain research. The manuscript focuses primarily on advances in understanding related to social information processing and interconnectivity among brain syst...

journal_title：Current opinion in pediatrics

authors： McPartland JC,Coffman M,Pelphrey KA

更新日期：2011-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the current evidence on the use of infection markers for diagnostic evaluation of sepsis in neonates. RECENT FINDINGS:Recent research in immunology has led to the discovery of cell surface antigens, chemokines, cytokines and acute phase proteins that can potentially be used to 'rule in' or ...

journal_title：Current opinion in pediatrics

authors： Ng PC,Lam HS

更新日期：2006-04-01 00:00:00