Abstract：
:Characteristic symptoms of fibromyalgia syndrome include widespread pain, fatigue, sleep abnormalities, and distress. Patients with fibromyalgia show psychophysical evidence of mechanical, thermal, and electrical hyperalgesia. Peripheral and central abnormalities of nociception have been described in fibromyalgia. Important nociceptor systems in the skin and muscles seem to undergo profound changes in patients with fibromyalgia through unknown mechanisms. They include sensitization of vanilloid receptor, acid-sensing ion channel receptors, and purino-receptors. Tissue mediators of inflammation and nerve growth factors can excite these receptors and cause extensive changes in pain sensitivity, but patients with fibromyalgia lack consistent evidence for inflammatory soft tissue abnormalities. Therefore, recent investigations have focused on central nervous system mechanisms of pain in fibromyalgia.
journal_name
Curr Pain Headache Repjournal_title
Current pain and headache reportsauthors
Staud R,Smitherman MLdoi
10.1007/s11916-002-0046-1keywords:
subject
Has Abstractpub_date
2002-08-01 00:00:00pages
259-66issue
4eissn
1531-3433issn
1534-3081journal_volume
6pub_type
杂志文章,评审abstract：:Weight gain is a common side effect of drugs used for headache prevention. Weight gain can adversely affect patient health, exacerbate comorbid metabolic disorders, and encourage noncompliance. Additionally, obesity may promote the chronification of episodic migraine. Few studies have looked specifically at the effect...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-008-0035-0
更新日期：2008-06-01 00:00:00
abstract：:Whiplash injuries are very common and usually are associated with rear-end collisions. However, a whiplash injury can be caused by any event that results in hyperextension and flexion of the cervical spine. These injuries are of serious concern to all consumers due to escalating cost of diagnosis, treatment, insurance...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-005-0007-6
更新日期：2005-10-01 00:00:00
abstract：: ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-019-0746-4
更新日期：2019-01-19 00:00:00
abstract：:Infantile colic is a self-limiting disorder of excessive infant crying or fussiness that peaks at 6 weeks of age and typically improves by 3 months of age. The etiology of infantile colic has yet to be definitively elucidated, but there is increasing research to support its relationship to migraine. The aims of this r...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-016-0558-8
更新日期：2016-05-01 00:00:00
abstract：:Migraine and tension-type headache (TTH) are highly prevalent primary headaches that remain underdiagnosed and undertreated in clinical practice. The similarities and differences between migraine and TTH may impose diagnostic challenges as well as management difficulties. In addition, the possibility of migraine chron...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-007-0232-2
更新日期：2007-12-01 00:00:00
abstract：:Significant improvement of neuropathic pain has been achieved with studies that have demonstrated efficacy of newer anticonvulsants in relieving this type of pain, by having a neuromodulatory effect on the hyperexcitable damaged nervous system. Two drugs from this class, gabapentin and lamotrigine, have been submitted...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-004-0054-4
更新日期：2004-06-01 00:00:00
abstract：PURPOSE OF REVIEW:Fibromyalgia (FM) is the second most common rheumatologic pain disorder after osteoarthritis with a multisystem presentation. While the treatment of FM in a clinical setting incorporates both pharmacologic and non-pharmacologic modalities, the present investigation reviews evolving literature on cogni...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-018-0688-2
更新日期：2018-04-04 00:00:00
abstract：:Fibromyalgia is a frequent cause of chronic widespread pain and affects up to 5% of the general population. Diagnosis and treatment have been especially challenging due to limited knowledge of etiology and poor response to conventional treatment of pain. Appreciation for the interactions of neurobiologic, psychologic,...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-005-0019-2
更新日期：2005-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Sickle cell disease (SCD) is a hematological disorder which leads to serious complications in multiple organ systems. While significant research has addressed many of the effects of acute pain episodes and end-organ damage connected to this disease, little has approached the chronic pain state associa...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-020-00854-y
更新日期：2020-03-21 00:00:00
abstract：:Empathy is a provider attribute that has been a topic of increased clinical interest, particularly as it relates to pain. This article examines various dimensions of the pain and empathy literature: definitions of empathy, research regarding the psychophysiology of empathy for pain, and research related to empathy in ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-008-0021-6
更新日期：2008-04-01 00:00:00
abstract：:The introduction of triptans (5-HT (1B/1D) agonists) into clinical practice has expanded the therapeutic options for doctors treating migraine sufferers. The triptans are available in several different formulations such as conventional oral tablets, orally disintegrating wafers, subcutaneous injections, nasal sprays, ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-005-0064-x
更新日期：2005-06-01 00:00:00
abstract：:New imaging technology allows us to study neurologic disorders that have had no previous structural basis. There have been recent reports on the involvement of nociceptive pathways in daily headache. A systematic review was performed using key words "chronic daily headache" and "imaging." This paper reviews the litera...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-003-0074-5
更新日期：2003-06-01 00:00:00
abstract：PURPOSE OF REVIEW:Chronic venous disease (CVD), although affecting up to 40% of the US population, is often underdiagnosed by healthcare professionals due to an incomplete understanding of the presenting symptoms. CVD is a common cause of lower extremity pain and discomfort, including aching, cramping, tingling, burnin...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-019-0759-z
更新日期：2019-03-04 00:00:00
abstract：:Although the comorbidity of migraine has been extensively studied, the relationships between cluster headache and psychiatric disease have not been well-addressed. In this review the available literature concerning cluster headache and depression, anxiety, bipolar disorder, aggression, suicide, and their implications ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-012-0313-8
更新日期：2013-02-01 00:00:00
abstract：:The literature on migraine triggers is reviewed, including the most common triggers, interactions between triggers, the research evidence related to the capacity of self-reported triggers to precipitate headaches, and the neurobiologic pathways by which triggers induce migraine attacks. An argument is developed agains...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-010-0112-z
更新日期：2010-06-01 00:00:00
abstract：:The clinical features of trigeminal autonomic cephalalgias (TACs), such as trigeminal distribution of pain, circadian/circannual rhythmicity, and ipsilateral cranial autonomic features, suggest a crucial role of the hypothalamus in the underlying pathophysiology of these primary headache disorders. Hypothalamic involv...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-010-0166-y
更新日期：2011-04-01 00:00:00
abstract：:Cancer pain is highly prevalent and often severe. Fortunately, most cancer pain can be readily managed, with up to 90% of patients responding well to standard interventions. However, breakthrough cancer pain-brief flares of severe pain superimposed on baseline pain-is common, difficult to manage, and often negatively ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-008-0042-1
更新日期：2008-08-01 00:00:00
abstract：PURPOSE OF REVIEW:To provide an update on recent developments in the understanding, diagnosis, and treatment of CSF-venous fistula (CVF). RECENT FINDING:CVF is a recently recognized cause of spontaneous intracranial hypotension (SIH), an important secondary headache, in which an aberrant connection is formed between t...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-020-00921-4
更新日期：2021-01-21 00:00:00
abstract：PURPOSE OF REVIEW:Athletic neurosurgical emergencies are injuries that can lead to mortality or significant morbidity and require immediate recognition and treatment. This review article discusses the epidemiology of sports-related traumatic brain injury (TBI) with an attempt to quantify the incidence of neurosurgical ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-016-0586-4
更新日期：2016-09-01 00:00:00
abstract：:More than 20 million US women suffer with migraine, two thirds of whom experience menstrually related migraine. Estrogen plays an important role in triggering migraine, and given the numerous hormonal fluctuations throughout a woman's lifetime, there are many opportunities for a hormonal impact. Accurate diagnosis is ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-007-0194-4
更新日期：2007-06-01 00:00:00
abstract：PURPOSE OF REVIEW:Neuromyelitis optica (NMO) classically features a clinical presentation that includes longitudinally extensive transverse myelitis and optic neuritis. However, many other pathognomonic phenomena have more recently been described in patients diagnosed with NMO, including intractable hiccups, vomiting, ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-017-0620-1
更新日期：2017-04-01 00:00:00
abstract：:Migraine and stroke are related in more than one way. Migraine with aura is a risk factor for ischemic stroke in women under age 45 years, particularly when combined with other risk factors such as smoking and oral contraceptives. Further, individuals with migraine with aura seem to have more white matter lesions and ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-012-0262-2
更新日期：2012-06-01 00:00:00
abstract：:Sexual hormones influence complex brain function and pain perception. Many psychophysical studies attempted to establish pain perception changes across menstrual cycle in animal models and healthy women or those with chronic pain. General results are quite uncertain in regard to consistent menstrual-related fluctuatio...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-011-0207-1
更新日期：2011-10-01 00:00:00
abstract：:Tension-type headache is the most common headache disorder, affecting approximately 40 % of Americans within a one-year span. Although the most common form, episodic tension-type headache, is rarely impairing, more frequent tension-type headache can occur with significant disability and psychological comorbidity. Appr...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-012-0301-z
更新日期：2012-12-01 00:00:00
abstract：:The association of traumatic exposures with posttraumatic stress disorder (PTSD) and other mental health conditions is well known. Patients with chronic pain, particularly headache disorders and fibromyalgia (FM), associated with psychological traumas need a special management strategy. Diagnosis of headache disorders...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-009-0057-2
更新日期：2009-10-01 00:00:00
abstract：:Migraine is a debilitating neurological disorder with grave consequences for both the individual and society. This review will focus on recent literature investigating how brain structures implicated in reward and aversion contribute to the genesis of migraine pain. There exist many overlapping and interacting brain r...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-014-0410-y
更新日期：2014-05-01 00:00:00
abstract：:Complex regional pain syndrome (CRPS) remains a challenging condition to diagnose and treat. There are few large-scale, randomized trials of pharmacologic agents, and most published studies are small, uncontrolled, or presented only in abstract form at meetings. The most commonly used agents, such as anticonvulsants, ...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-007-0020-z
更新日期：2007-02-01 00:00:00
abstract：:Neurostimulation techniques for the treatment of primary headache syndromes, particularly for chronic cluster headache (CCH), have received much interest in the recent years. Occipital nerve stimulation (ONS) has yielded favourable clinical results, and is becoming a routine treatment for refractory chronic cluster he...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-013-0324-0
更新日期：2013-05-01 00:00:00
abstract：:Opioids have become the unequivocal therapy of choice in treating many varieties of chronic pain. With the increased prescription of opioids, some unintended consequences have occurred. After prolonged opioid exposure, opioid-induced hyperalgesia (OIH), the paradoxical effect that opioid therapy may in fact enhance or...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-010-0171-1
更新日期：2011-04-01 00:00:00
abstract：:Pain can be a significant problem for the patient with advanced cancer, particularly if bone metastases are present. Radiation therapy is efficacious and has been a mainstay in the treatment of pain from bone metastases. In the past decade, radiosurgery has developed into a successful adjunct treatment for these patie...
journal_title：Current pain and headache reports
pub_type： 杂志文章,评审
doi：10.1007/s11916-009-0044-7
更新日期：2009-08-01 00:00:00
