Abstract:
:This cross-sectional study provides values for lumbar spine bone mineral content (BMC) and density (BMD) in 41 healthy full-term born Finnish infants, 19 boys and 22 girls, during the first year of life measured by dual energy X-ray absorptiometry (DXA) using the Lunar DPX densitometer. Lumbar BMC correlated with the weight (r=0.733; P=0.000), length (r=0.677; P=0.000), standardized length (r=0.315; r=0.045) and age at examination (r=0.314; P=0.045), and with the bone area (r=0.736; P=0.000). Infants with < or =-1 SD scores for lengths at examination had significantly lower BMC values [mean (SD); 1.79 (0.66) g] than infants with SD scores above -1 SD [2.27 (0.46) g] (P=0.011). Exclusive breast feeding did not correlate with the lumbar BMC values (r=-0.039; P=0.811). No differences were found in lumbar spine BMC (P=0.097), BMD (P=0.254) and bone area (P=0.094) values between boys and girls. In order to determine the predictive value of the anthropometric measurements on lumbar BMC, stepwise multiple regression analysis were performed, bone area and present weight were the only independent variables which explained 67.6% of the variance in the BMC values. The present cross-sectional data imply that, in healthy term infants, patterns of relative linear growth during the first year of life are related to the lumbar BMC values. In future, careful longitudinal measurements of linear growth are needed to study connections between growth patterns and bone mineral status in infancy.
journal_name
Clin Physiol Funct Imagingjournal_title
Clinical physiology and functional imagingauthors
Kurl S,Heinonen K,Jurvelin JS,Länsimies Edoi
10.1046/j.1475-097x.2002.00422.xkeywords:
subject
Has Abstractpub_date
2002-05-01 00:00:00pages
222-5issue
3eissn
1475-0961issn
1475-097Xpii
422journal_volume
22pub_type
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