Regulation of Arabidopsis cryptochrome 2 by blue-light-dependent phosphorylation.

Abstract:

:Cryptochromes are blue/ultraviolet-A light receptors that mediate various light responses in plants and animals. But the initial photochemical reaction of cryptochrome is still unclear. For example, although most photoreceptors are known to undergo light-dependent protein modification such as phosphorylation, no blue-light dependent phosphorylation has been reported for a cryptochrome. Arabidopsis cryptochrome 2 (cry2) mediates light regulation of seedling development and photoperiodic flowering. The physiological activity and cellular level of cry2 protein are light-dependent, and protein protein interactions are important for cry2 function. Here we report that cry2 undergoes a blue-light-dependent phosphorylation, and that cry2 phosphorylation is associated with its function and regulation. Our results suggest that, in the absence of light, cry2 remains unphosphorylated, inactive and stable; absorption of blue light induces the phosphorylation of cry2, triggering photomorphogenic responses and eventually degradation of the photoreceptor.

journal_name

Nature

journal_title

Nature

authors

Shalitin D,Yang H,Mockler TC,Maymon M,Guo H,Whitelam GC,Lin C

doi

10.1038/nature00815

keywords:

subject

Has Abstract

pub_date

2002-06-13 00:00:00

pages

763-7

issue

6890

eissn

0028-0836

issn

1476-4687

pii

nature00815

journal_volume

417

pub_type

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