Abstract:
:Cryptochromes are blue/ultraviolet-A light receptors that mediate various light responses in plants and animals. But the initial photochemical reaction of cryptochrome is still unclear. For example, although most photoreceptors are known to undergo light-dependent protein modification such as phosphorylation, no blue-light dependent phosphorylation has been reported for a cryptochrome. Arabidopsis cryptochrome 2 (cry2) mediates light regulation of seedling development and photoperiodic flowering. The physiological activity and cellular level of cry2 protein are light-dependent, and protein protein interactions are important for cry2 function. Here we report that cry2 undergoes a blue-light-dependent phosphorylation, and that cry2 phosphorylation is associated with its function and regulation. Our results suggest that, in the absence of light, cry2 remains unphosphorylated, inactive and stable; absorption of blue light induces the phosphorylation of cry2, triggering photomorphogenic responses and eventually degradation of the photoreceptor.
journal_name
Naturejournal_title
Natureauthors
Shalitin D,Yang H,Mockler TC,Maymon M,Guo H,Whitelam GC,Lin Cdoi
10.1038/nature00815keywords:
subject
Has Abstractpub_date
2002-06-13 00:00:00pages
763-7issue
6890eissn
0028-0836issn
1476-4687pii
nature00815journal_volume
417pub_type
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