Parental smoking: asthma and wheezing illnesses in infants and children.

abstract：:The concept of personalised medicine is likely to revolutionise the treatment of adult obstructive sleep apnoea as a result of recent advances in the understanding of disease heterogeneity by identifying clinical phenotypes, pathophysiological endotypes, biomarkers and treatable traits. Children with the condition sho...

journal_title：Paediatric respiratory reviews

authors： Siriwardhana LS,Nixon GM,Horne RSC,Edwards BA

更新日期：2020-11-01 00:00:00

abstract：:Bronchiolitis is a common disease in infancy, mostly due to Respiratory Syncytial Virus and Rhinovirus. In addition to acute infection, viral bronchiolitis is responsible for sequelae including recurrent wheezing and asthma. The analysis of the viral characteristics and of the pathogenesis of the infection shows diffe...

journal_title：Paediatric respiratory reviews

authors： Vandini S,Calamelli E,Faldella G,Lanari M

更新日期：2017-09-01 00:00:00

abstract：:There have been major advances in the surgery for oesophageal atresia (OA) and tracheo-oesophageal fistula(TOF) with survival now exceeding 90%. The standard open approach to OA and distal TOF has been well described and essentially unchanged for the last 60 years. Improved survival in recent decades is most attributa...

journal_title：Paediatric respiratory reviews

authors： Teague WJ,Karpelowsky J

更新日期：2016-06-01 00:00:00

abstract：:The Clinical and Functional Translation of CFTR (CFTR2) project presents a novel approach to clinical and functional annotation of mutations identified in disease-causing genes. Phenotype and genotype information on approximately 40,000 cystic fibrosis (CF) patients were collected from registries and large clinics. Th...

journal_title：Paediatric respiratory reviews

authors： Castellani C,CFTR2 team.

更新日期：2013-05-01 00:00:00

abstract：:Bacterial 'colonisation' of the nasopharynx by potential bacterial pathogens is frequent in early childhood and is frequent as part of a dynamic process in which the microbiota of the oral and nasopharynx are established. New understanding recognizes this process is evolving and that competition and likely regulation ...

journal_title：Paediatric respiratory reviews

authors： Pelton SI

更新日期：2012-09-01 00:00:00

abstract：:Significant improvement in the survival of patients with CF has been achieved in the last decades. The improved clinical status of the patients is mainly the result of a better understanding of the natural course of infection and inflammation in CF that has led to the implementation of strategies that increase the lif...

journal_title：Paediatric respiratory reviews

authors： Kerem E

更新日期：2017-09-01 00:00:00

abstract：:The major morbidity and mortality associated with cerebral palsy (CP) relates to respiratory compromise. This manifests through repeated pulmonary aspiration, airway colonization with pathogenic bacteria, the evolution of bronchiectasis and sleep disordered breathing. An accurate assessment involving a multidisciplina...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA,Follett J,Van Asperen PP

更新日期：2009-03-01 00:00:00

abstract：:Polysomnography is an elaborate diagnostic test composed of numerous data-collecting sensors working concomitantly to aid in the evaluation of varied sleep disorders in all age groups. Polysomnography is the study of choice for the assessment of pediatric sleep-disordered breathing, including obstructive sleep apnea s...

journal_title：Paediatric respiratory reviews

authors： Stowe RC,Afolabi-Brown O

更新日期：2020-04-01 00:00:00

abstract：:Cardiac abnormalities occur in association with many of the neuromuscular disorders that present in childhood. Genetic defects involving the cytoskeleton, nuclear membrane, and mitochondrial function have all been described in patients with skeletal myopathy and cardiac involvement. The most common classes of neuromus...

journal_title：Paediatric respiratory reviews

authors： Hsu DT

更新日期：2010-03-01 00:00:00

abstract：:Chronic cough has been variably defined as a cough lasting longer than 3, 4 or 8 weeks. Many post viral or pertussis like illnesses are associated with prolonged coughing that resolves over time. Management involves first trying to make a diagnosis and identify the presence of any underlying condition. Targeted treatm...

journal_title：Paediatric respiratory reviews

authors： Shields MD,Doherty GM

更新日期：2013-06-01 00:00:00

abstract：:Primary ciliary dyskinesia (PCD), also known as immotile-cilia syndrome, is a rare genetic disease that is inherited in an autosomal recessive manner. Several studies have explored certain aspects of PCD in the Arab world, yet much is still lacking in terms of identifying the different characteristics of this disease....

journal_title：Paediatric respiratory reviews

authors： Hammoudeh S,Gadelhak W,Janahi IA

更新日期：2019-02-01 00:00:00

abstract：:Asthma is a common disease in paediatrics and adults with a significant morbidity, mortality, and financial burden worldwide. Asthma is now recognized as a heterogeneous disease and emerging clinical and laboratory research has elucidated understanding of asthma's underlying immunology. The future of asthma is classif...

journal_title：Paediatric respiratory reviews

authors： Gans MD,Gavrilova T

更新日期：2020-11-01 00:00:00

abstract：:The lung is continually at risk of exposure to noxious environmental agents and respiratory pathogens. An elaborate series of defence mechanisms have been developed to protect the airways from these insults. The lower respiratory tract is protected by local mucociliary mechanisms that involve the integration of the ci...

journal_title：Paediatric respiratory reviews

authors： Chilvers MA,O'Callaghan C

更新日期：2000-03-01 00:00:00

abstract：:Asthma is one of the commonest chronic conditions in children and can occasionally be fatal. Little has changed regarding the risk factors for children dying from asthma in the last 30 years. The majority of deaths from asthma occur in children from socio-economically disadvantaged backgrounds. These should be prevent...

journal_title：Paediatric respiratory reviews

authors： Herrera AM,Fitzgerald DA

更新日期：2018-06-01 00:00:00

abstract：:The obstructive sleep apnea syndrome is common and its prevalence is expected to increase with the current obesity epidemic. If left untreated, it is associated with important morbidity such as growth failure, neurocognitive impairment, systemic and pulmonary hypertension, and endothelial dysfunction. Recent research ...

journal_title：Paediatric respiratory reviews

authors： Tapia IE,Marcus CL

更新日期：2013-09-01 00:00:00

abstract：:Despite evidence showing an improvement in nutritional outcomes following diagnosis by newborn screening (NBS) for cystic fibrosis (CF), the impact on pulmonary outcomes has been less clear. In this review the approaches to measurement of early lung function and knowledge gained from NBS CF cohorts will be described. ...

journal_title：Paediatric respiratory reviews

authors： Davies G

更新日期：2020-08-20 00:00:00

abstract：:Severe acute respiratory syndrome (SARS) is a newly described respiratory infection with pandemic potential. The causative agent is a new strain of coronavirus most likely originating from wild animals. This disease first emerged in November 2002 in Guangdong Province, China. Early in the outbreak the infection had be...

journal_title：Paediatric respiratory reviews

authors： Zhong NS,Wong GW

更新日期：2004-12-01 00:00:00

abstract：:Foreign body aspiration is a common accident in children and represents an important cause of morbidity and mortality. Diagnosis of this condition demands a high degree of suspicion since physical examination and basic radiology exams have low sensitivity. It is more frequent in children younger than 3 years of age, p...

journal_title：Paediatric respiratory reviews

authors： Lima JA,Fischer GB

更新日期：2002-12-01 00:00:00

abstract：:Vocal cord dysfunction is characterised by paradoxical vocal cord adduction that occurs during inspiration, resulting in symptoms of dyspnoea, wheeze, chest or throat tightness and cough. Although the condition is well described in children and adults, confusion with asthma often triggers the use of an aggressive trea...

journal_title：Paediatric respiratory reviews

authors： Noyes BE,Kemp JS

更新日期：2007-06-01 00:00:00

abstract：:With the advent of improved antenatal imaging over the past 10 years, the diagnosis, assessment and management of congenital cystic lung abnormalities have changed. These were once considered the exclusive domain of the surgeon, who had the authority to operate on all congenital cystic lung abnormalities regardless of...

journal_title：Paediatric respiratory reviews

authors： Fitzgerald DA

更新日期：2007-03-01 00:00:00

abstract：:Radiological evaluation of the airway has been used as a screening tool and an adjunct to endoscopy for many years. It provides non-invasive data on the structure of the airway, often avoiding the risk of general anaesthesia. Standard radiographs provide some information on the intricate anatomy of the paediatric airw...

journal_title：Paediatric respiratory reviews

authors： Bradshaw K

更新日期：2001-03-01 00:00:00

abstract：:Newborn screening for cystic fibrosis remains controversial because there is still little agreement that prophylactic interventions provide substantial long-term benefits. In such situations, where there are some medical benefits and the costs are not prohibitive, it is important to consider the psychosocial implicati...

journal_title：Paediatric respiratory reviews

authors： Parsons EP,Bradley DM

更新日期：2003-12-01 00:00:00

abstract：:Primary ciliary dyskinesia (PCD) is a rare, autosomal recessive condition. The signs and symptoms are due to congenital abnormalities of ciliary structure and function, resulting in impaired mucociliary clearance. This affects the ciliated epithelium lining the nose, sinuses, Eustachian tube and airways. As a conseque...

journal_title：Paediatric respiratory reviews

authors： Hogg C

更新日期：2009-06-01 00:00:00

abstract：:The thorax consists of the rib cage and the respiratory muscles. It houses and protects the various intrathoracic organs such as the lungs, heart, vessels, esophagus, nerves etc. It also serves as the so-called "respiratory pump" that generates the movement of air into the lungs while it prevents their total collapse ...

journal_title：Paediatric respiratory reviews

authors： Koumbourlis AC

更新日期：2014-09-01 00:00:00

abstract：:It is reasonable to suggest that Telemedicine could help in the management of chronic diseases by giving patients more flexibility to remain at home with opportunities to forward electronic data to healthcare professionals, reduce hospital emergency attendances and reduce overall costs. The reality, particularly in cy...

journal_title：Paediatric respiratory reviews

authors： Lenney W

更新日期：2018-03-01 00:00:00

abstract：:Asthma is most frequent chronic disease in childhood. Childhood asthma frequently persists to adulthood and the available evidence suggests that the severity of childhood asthma predicts the severity of asthma in the adulthood. To prevent long term remodeling of the airways and improve prognosis, early diagnosis and t...

journal_title：Paediatric respiratory reviews

authors： Pohunek P

更新日期：2006-01-01 00:00:00

abstract：:The obstructive sleep apnoea syndrome (OSAS) is common in children and results in several complications when untreated. Considering that children are undergoing important brain development, recent research has focused on neurocognitive and behavioural (NCB) complications of OSAS. Studies have shown that treatment of p...

journal_title：Paediatric respiratory reviews

authors： Konstantinopoulou S,Tapia IE

更新日期：2016-09-01 00:00:00

abstract：:The anatomical and functional development of the lung appears especially vulnerable to a whole range of insults during gestation and the first few years of life. A significant proportion of adult lung disease originates in utero or early infancy. Most publications on this topic are descriptive retrospective studies. A...

journal_title：Paediatric respiratory reviews

authors： Merkus PJ

更新日期：2003-03-01 00:00:00

abstract：:Conflict between the demands of the environment in which a child lives and the child's intrinsic sleep signature, produces stress-behaviour difficulties in the child. Distorted development, especially distorted brain development, often leads to distorted intrinsic sleep signatures. The sleep-behaviour outcome, arising...

journal_title：Paediatric respiratory reviews

authors： Nunn K

更新日期：2014-03-01 00:00:00

abstract：:This article will review traditional and newer microbiological techniques for the diagnosis of mycobacterial respiratory infections. It will concentrate on the diagnosis of infections due to Mycobacterium tuberculosis, the main mycobacterium causing respiratory infections of clinical and public health importance. The ...

journal_title：Paediatric respiratory reviews

authors： Andresen D

更新日期：2007-09-01 00:00:00