Tc-99m sulfur colloid and Tc-99m tagged red blood cell methods are comparable for detecting lower gastrointestinal bleeding in clinical practice.


PURPOSE:The objective of this study was to determine whether the Tc-99m red blood cells (Tc-99m RBC) method has a true advantage over the Tc-99m sulfur colloid (Tc-99m SC) technique in a busy clinical practice for detecting and localizing lower gastrointestinal bleeding sites. METHODS:Three hundred fifty-nine consecutive gastrointestinal bleeding studies performed during the past 4 years were reviewed retrospectively. One hundred ninety-three scans were obtained with Tc-99m SC (scan duration, 30 minutes) and 138 studies were performed after the administration of Tc-99m RBC (scan duration, 1 hour). In addition, 28 examinations with Tc-99m SC were followed immediately by Tc-99m RBC scans for a duration of several hours. The results of the two methods were analyzed and the performance of the two techniques was compared. RESULTS:Among 193 scans performed using the Tc-99m SC method, 47 (24.4%) successfully identified the location of the bleeding site, whereas in 138 scans performed using Tc-99m RBC, 38 (27.5%) were successful for this purpose. In the remaining 28 scans in which the Tc-99m SC scan was followed by the Tc-99m RBC study, only 4 (14.3%) positive bleeding sites were identified after a prolonged imaging period. DISCUSSION:The theoretical advantages of the Tc-99m RBC technique compared with the Tc-99m SC method cannot be substantiated by this study. Our findings suggest that the efficacy of these two methods is nearly equal at a practical level. CONCLUSION:The simpler and cost-effective Tc-99m SC method is as efficient as the Tc-99m RBC method when the scanning time is limited to 1 hour and optimal imaging and interpretation schemes are used.


Clin Nucl Med


Ponzo F,Zhuang H,Liu FM,Lacorte LB,Moussavian B,Wang S,Alavi A





Has Abstract


2002-06-01 00:00:00












  • Scintigraphic findings in a Brodie's abscess.

    abstract::A 9-year-old girl had a 6-month history of left hip pain. Radiographs of the left hip showed a metaphyseal osteolytic lesion with sclerotic borders in the femoral neck. Tc-99m MDP bone imaging and a Ga-67 scan showed focal areas of increased activity in the left femoral neck. These areas of increased uptake correspond...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Silva F,Laguna R,Acevedo M,Ruíz C,Orduña E

    更新日期:1995-10-01 00:00:00

  • Respiratory artefact causing malpositioning of liver dome lesion in right lower lung.

    abstract::The new combined positron emission (PET)/computed tomographic (CT) scanners have many advantages over PET scanners alone. However, physicians must be aware of the potential artefacts observed in PET/CT scanners. A body PET/CT was performed on an 81-year-old man with colorectal cancer. The CT-based, attenuation-correct...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Sarikaya I,Yeung HW,Erdi Y,Larson SM

    更新日期:2003-11-01 00:00:00

  • Elevated FDG activity in lymph nodes as well as the spleen and liver in a patient with adult-onset still disease.

    abstract::A 66-year-old woman had fever, rash, and joint pain. Physical examination revealed multiple enlarged lymph nodes. A possibility of lymphoma was considered and FDG PET/CT was performed, which demonstrated elevated FDG activity not only in many lymph nodes but also in the spleen and liver. However, adult-onset Still dis...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Cai L,Chen Y,Huang Z

    更新日期:2012-10-01 00:00:00

  • Bone scintigraphy in acute intraosseous disc herniation.

    abstract::A 57-year-old woman initially presented with the acute onset of low back pain after gardening. Plain film at that time was reported as showing Scheurmann's disease of the lumbar spine. The pain resolved slowly, but recurred acutely after minimal trauma 5 months later. Bone scintigraphy revealed increased uptake in L4 ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Crawford BA,van der Wall H

    更新日期:2007-10-01 00:00:00

  • Atypical findings of discordant bone scan and radiographs in transient osteoporosis of the hip: case report and review of the literature.

    abstract::The authors report atypical findings of discordant bone scans and radiography seen in a patient with transient osteoporosis of the hip (TOH). Presented in the case of a 60-year-old man who had spontaneous onset of left hip pain which worsened for 2 months with weight-bearing on the affected side. Initial and follow-up...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章,评审


    authors: Tan TX,Dardani M,Neal DJ,Mueller CF,Pozderac RV

    更新日期:1998-03-01 00:00:00

  • Kinetics of Tc-99m sestamibi and Tc-99m tetrofosmin in a case of parathyroid adenoma.

    abstract::The uptake of Tc-99m tetrofosmin (TF) is reported in a case of parathyroid adenoma. A 65-year-old woman was studied on different days with TF, Tc-99m sestamibi (MIBI) and Tl-201 chloride (Tl). TF and MIBI injections were preceded by oral administration of potassium perchlorate. Clear identification of the adenoma was ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Mansi L,Rambaldi PF,Marino G,Pecori B,Del Vecchio E

    更新日期:1996-09-01 00:00:00

  • The use of nuclear medicine procedures in the diagnosis of Budd-Chiari syndrome.

    abstract::The case history of a patient with Budd-Chiari syndrome (BCS) is described. The underlaying disease proved to be essential thrombocytosis. Congential elliptocytosis was also present. The value of the conventional liver scan, percutaneous splenoportoscintigraphy and isotopic phlebography of the inferior vena cava in th...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Thijs LG,Heidendal GA,Huijgens PC,Mol JJ,Verkuyl M

    更新日期:1978-10-01 00:00:00

  • Spinal uptake mimicking metastasis in SPECT/CT bone scan in a patient with superior vena cava obstruction.

    abstract::A 46-year-old female patient with a mediastinal neuroendocrine carcinoma complicated by superior vena cava syndrome was referred for a bone metastatic workup. Bone scan with SPECT/CT showed several vertebral fixations without alterations on the unenhanced CT, but a CT scan with injection of contrast media showed verte...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Rager O,Nkoulou R,Garibotto V,Boudabbous S,Arditi D

    更新日期:2013-11-01 00:00:00

  • Effect of reserpine on salivary gland radioiodine uptake in thyroid cancer.

    abstract::Nine patients with thyroid cancer were treated with reserpine in an attempt to reduce radiation exposure to the salivary glands from 100-150 mCi doses of I-131 therapy to thyroid remnants or metastases. Three control patients were not treated with reserpine but did receive 100-150 mCi of I-131. Parotid/background rati...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Levy HA,Park CH

    更新日期:1987-04-01 00:00:00

  • Cholescintigraphy in gallbladder carcinoma.

    abstract::Findings on cholescintigraphy in gallbladder carcinoma are described in five patients. Four patients presenting with acute cholecystitis had nonvisualization of the gallbladder with normal hepatoenteric transit time. One of these had a large portal mass and two had liver metastasis as additional findings. The fifth pa...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Colletti PM,Ralls PW,Siegel ME,Halls JM

    更新日期:1986-04-01 00:00:00

  • Renal cell carcinoma detected on Tc-99m-labeled red blood cell imaging.

    abstract::A 61-year-old-man with persistent anemia was referred for a Tc-99m-labeled red blood cell (RBC) scan to detect any source of gastrointestinal bleeding. RBC scintigraphy revealed a hypervascular mass in the left renal fossa with functional loss in that kidney, suggesting the possibility of a renal cell carcinoma (RCC)....

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Cortes J,Alonso JI,Ruiz-Oliva F,Alvarez S,Ormijana JS,Caton B,Alcorta P

    更新日期:2003-11-01 00:00:00

  • Relationship between myocardial perfusion-gated SPECT and the performance of coronary revascularization in patients with ischemic cardiomyopathy.

    abstract:PURPOSE:Ischemic cardiomyopathy (ICM) is a disease with high morbidity and mortality. There are several published studies on the evolution and prognosis of patients with ICM. However, reports on the therapeutic management in clinical practice are scarce. The aim of this study was to analyze coronary revascularization (...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Romero-Farina G,Candell-Riera J,Aguadé-Bruix S,Ferreira-Gonzalez I,Igual A,García-Dorado D

    更新日期:2012-10-01 00:00:00

  • Obscured bone metastases after administration of hematopoietic factor on FDG-PET.

    abstract::We describe interesting imaging features on a FDG-PET scan in a patient with bony metastases from a rare tumor. The lesions were obscured by intense bone marrow activity after the administration of hematopoietic factor at the time of diagnosis. Correlative MRI, CT scan, and pathology findings have also been illustrate...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Chhabra A,Batra K,Makler PT Jr

    更新日期:2006-06-01 00:00:00

  • Tuberculous meningitis of the Sylvian fissure.

    abstract::A 66-year-old woman had autopsy-proven miliary tuberculosis, with regional involvement of the meninges of the left Sylvian fissure. Radionuclide studies of the brain demonstrated the unusual findings of increased perfusion to the left hemisphere and linear increased activity corresponding to the left Sylvian fissure. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Klingensmith WC 3rd,Datu J

    更新日期:1978-08-01 00:00:00

  • A case of three synchronous primary tumors demonstrated by F-18 FDG PET.

    abstract::We present an F-18 FDG PET scan which demonstrates 3 synchronous primary malignancies. The patient is a 61-year-old man who presented with weight loss and dysphagia. He was initially diagnosed with squamous cell carcinoma of the midesophagus, and was then found to have an adenocarcinoma in the right lung. A staging PE...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Mittra E,Vasanawala M,Niederkohr R,Rodriguez C,Segall G

    更新日期:2007-08-01 00:00:00

  • Tc-99m galactosyl-neoglycoalbumin hepatic scintigraphy in fulminant hepatic failure.

    abstract::Tc-99m galactosyl-neoglycoalbumin (NGA) is a new liver imaging agent that specifically binds to a hepatocyte specific membrane receptor, the hepatic binding protein. Scintigraphy with Tc-99m NGA is a noninvasive method that provides functional images of the liver. This report deals with one case of fulminant hepatic f...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Moragas M,Pavía J,Ginés A,Ros D,Solá M,Huguet M,Pons F,Setoain J

    更新日期:1995-04-01 00:00:00

  • Pigmented villonodular synovitis and giant cell tumor of the tendon sheath: scintigraphic findings in 10 cases.

    abstract::The purpose of this report was to determine the pattern of thallium (T1-201) uptake in pigmented villonodular synovitis (PVNS) and giant cell tumor of the tendon sheath (GCTTS) and to evaluate for features that might help to distinguish these lesions from malignant disease. Scintigraphic images from patients subsequen...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Mackie GC

    更新日期:2003-11-01 00:00:00

  • Normal variants of a photon-deficient area in the lower sternum demonstrated by bone SPECT.

    abstract:PURPOSE:A highly variable normal appearance of the sternal area makes interpretation difficult on planar bone imaging. These normal variants occur especially in the area above the xiphoid process of the sternum in which an oval photopenic area on anterior planar images may be seen. This finding is most likely caused by...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Han JK,Shih WJ,Stipp V,Magoun S

    更新日期:1999-04-01 00:00:00

  • Progressive Hydrocephalus Due to Ventriculoperitoneal Shunt Infection: Detection With FDG PET CT.

    abstract::Ventriculoperitoneal shunt malfunction is common in patients after shunt surgery. Imaging is done to reveal the underlying cause and confirm the diagnosis. Shunt infection is one of the common causes of shunt malfunction. FDG PET CT is an accepted infection imaging tool and can be used to diagnose shunt infection accu...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Mathew B,Purandare NC,Agrawal A,Shah S,Puranik A,Rangarajan V

    更新日期:2020-03-01 00:00:00

  • 99mTc-HYNIC-TOC in the Evaluation of Recurrent Tumor-Induced Osteomalacia.

    abstract:PURPOSE:Tumor-induced osteomalacia (TIO) is rare paraneoplastic disorder generally caused by small benign neoplasm. Somatostatin receptor imaging has emerged as imaging of the choice in the localization of the causative tumors in new patients with clinical diagnosis of TIO. An accurate localization of the causative tum...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Shi X,Jing H,Li F,Zhao Y,Wang Z,Huo L

    更新日期:2019-03-01 00:00:00

  • Increased FDG activity in a dermatofibroma in esophageal cancer patient.

    abstract::PET using the radiotracer (18)F-FDG is used for staging patients with esophageal cancer. Nonmalignant conditions, mainly inflammation and some benign tumors, however, can cloud the clinical picture by taking up FDG and producing a false-positive result. We report the case of a 46 year-old man with squamous cell carcin...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Bingham BA,Hatef DA,Chevez-Barrios P,Blackmon SH,Kim MP

    更新日期:2013-03-01 00:00:00

  • FDG PET for imaging pericardial manifestations of Hodgkin lymphoma.

    abstract::A 61-year-old man with Hodgkin lymphoma (mixed type), with lymph node manifestations and extranodal and bone marrow involvement in both supra- and infradiaphragmatic locations (stage 4), had dyspnea and tachycardia on echocardiography. There were pleural and pericardial effusions and thickening of the epicardium and p...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Buchmann I,Wandt H,Wahl A,Reske SN

    更新日期:2003-09-01 00:00:00

  • Prognostic significance of left ventricular dyssynchrony by phase analysis of gated SPECT in medically treated patients with dilated cardiomyopathy.

    abstract:PURPOSE:The study aimed to investigate the value of clinical variables and rest gated single-photon emission computed tomography (SPECT) in predicting cardiac deaths in medically treated dilated cardiomyopathy (DCM) patients. METHODS:This is a retrospective study. Fifty-six consecutive hospitalized DCM patients who un...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Wang L,Yang MF,Cai M,Zhao SH,He ZX,Wang YT

    更新日期:2013-07-01 00:00:00

  • A Rare Case of Omentum Invasive Prostate Cancer: Staging With PSMA PET/CT Imaging and Response to Systemic Therapy.

    abstract::The omentum is a rare metastatic site for prostatic adenocarcinoma. We present a case of metastatic castrate-resistant prostate cancer, with progressive omentum invasive prostate cancer identified on prostate-specific membrane antigen (PSMA) PET/CT scan. Omental biopsy revealed metastatic prostate adenocarcinoma, and ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Ladwa R,Gustafson S,McCaffrey E,Miles K,O'Byrne K

    更新日期:2017-06-01 00:00:00

  • Radioguided surgery of thyroid carcinoma recurrences: the role of preoperative (99m)Tc-labeled human serum albumin macroaggregates-SPECT/CT mapping.

    abstract::Reoperative surgery in the neck for recurrent differentiated thyroid cancer (DTC) is associated with increased morbidity compared with primary surgery. Radioguided occult lesion localization was recently proposed in patients with DTC recurrences. Here we report on the combination of radioguided occult lesion localizat...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Giovanella L,Suriano S,Lunghi L,Bongiovanni M,Ceriani L

    更新日期:2013-04-01 00:00:00

  • The noninvasive diagnosis of isolated right ventricular infarction.

    abstract::A rare case of isolated right ventricular infarction (RVI) is described. The lack of clinical and electrocardiographic findings characteristic of isolated RVI makes this pathology a diagnostic challenge. The role of the radionuclide scintigraphic procedures as a single possible tool for the diagnosis of isolated RVI i...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Garty I,Antonelli D,Barzilay J

    更新日期:1984-12-01 00:00:00

  • Tips for leaders, Part II: Leading a private practice physician group.

    abstract::Leaders of private practice groups face many challenges. Establishing proper governance, having a good mission statement and business plan, having good participation by the members in administrative practice activities, and establishing proper channels of communication are some important steps. Once that is done, effi...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Harolds JA

    更新日期:2011-09-01 00:00:00

  • Focal splenic FDG uptake in a patient with Kala-Azar (visceral leishmaniasis).

    abstract::We present a woman with a history of Gaucher disease and secondary portal hypertension. She went to hospital for treatment of resistant fever without apparent cause. A conventional study of fever of unknown origin did not show any pathology. For this reason, she was referred to our department for a PET/CT, which did n...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Fuertes J,Garcia-Bennett JR,Iftimie S,Danús M,Abreu JA

    更新日期:2014-04-01 00:00:00

  • Catheter-related focal FDG activity on whole body PET imaging.

    abstract:INTRODUCTION:Whole body FDG positron emission tomography (PET) scan is increasingly being used in the management of a variety of cancers and infections. Cancer patients and other very sick patients have central venous catheters, which could be associated with common complications like thrombosis and infections. We desc...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Bhargava P,Kumar R,Zhuang H,Charron M,Alavi A

    更新日期:2004-04-01 00:00:00

  • Lung uptake of technetium-99m phosphate compounds after liver transplantation.

    abstract::Pulmonary calcification can be detected easily using Tc-99m phosphate compounds. Lung uptake of Tc-99m bone imaging agents was observed in two patients after liver transplantation. Transient hypercalcemia due to calcium infusion during hepatic transplantation may be responsible for the pulmonary calcification. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Raisis IP,Park CH,Yang SL,Maddrey W

    更新日期:1988-03-01 00:00:00