Tc-99m sulfur colloid and Tc-99m tagged red blood cell methods are comparable for detecting lower gastrointestinal bleeding in clinical practice.

Abstract:

PURPOSE:The objective of this study was to determine whether the Tc-99m red blood cells (Tc-99m RBC) method has a true advantage over the Tc-99m sulfur colloid (Tc-99m SC) technique in a busy clinical practice for detecting and localizing lower gastrointestinal bleeding sites. METHODS:Three hundred fifty-nine consecutive gastrointestinal bleeding studies performed during the past 4 years were reviewed retrospectively. One hundred ninety-three scans were obtained with Tc-99m SC (scan duration, 30 minutes) and 138 studies were performed after the administration of Tc-99m RBC (scan duration, 1 hour). In addition, 28 examinations with Tc-99m SC were followed immediately by Tc-99m RBC scans for a duration of several hours. The results of the two methods were analyzed and the performance of the two techniques was compared. RESULTS:Among 193 scans performed using the Tc-99m SC method, 47 (24.4%) successfully identified the location of the bleeding site, whereas in 138 scans performed using Tc-99m RBC, 38 (27.5%) were successful for this purpose. In the remaining 28 scans in which the Tc-99m SC scan was followed by the Tc-99m RBC study, only 4 (14.3%) positive bleeding sites were identified after a prolonged imaging period. DISCUSSION:The theoretical advantages of the Tc-99m RBC technique compared with the Tc-99m SC method cannot be substantiated by this study. Our findings suggest that the efficacy of these two methods is nearly equal at a practical level. CONCLUSION:The simpler and cost-effective Tc-99m SC method is as efficient as the Tc-99m RBC method when the scanning time is limited to 1 hour and optimal imaging and interpretation schemes are used.

journal_name

Clin Nucl Med

authors

Ponzo F,Zhuang H,Liu FM,Lacorte LB,Moussavian B,Wang S,Alavi A

doi

10.1097/00003072-200206000-00003

keywords:

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

405-9

issue

6

eissn

0363-9762

issn

1536-0229

journal_volume

27

pub_type

杂志文章
  • Comparison of Tc-99m MIBI and TI-201/Tc-99m pertechnetate for diagnosis of primary hyperparathyroidism.

    abstract::The purpose of this study was to directly compare the efficacy of Tc-99m MIBI with TI-201/Tc-99m pertechnetate scintigraphy for localizing parathyroid adenomas in patients with primary hyperparathyroidism. Of 21 patients suspected of having primary hyperparathyroidism who had undergone both studies, 14 had subsequent ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199608000-00002

    authors: Rauth JD,Sessions RB,Shupe SC,Ziessman HA

    更新日期:1996-08-01 00:00:00

  • Erythema nodosum leprosum reaction of leprosy causing the double stripe sign on bone scan. Case report.

    abstract::Leprosy is a disease that is widely distributed in underdeveloped tropical regions, with cases also occurring in the United States. The bone scan findings in a patient with leprosy who had developed a reactional state of the disease, erythema nodosum leprosum, are presented. His scan showed bilaterally symmetrical dou...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198703000-00012

    authors: Datz FL

    更新日期:1987-03-01 00:00:00

  • Differential diagnosis of idiopathic fibrosis from malignant lymphadenopathy with PET and F-18 fluorodeoxyglucose.

    abstract::Idiopathic fibrosis and malignant lymphoma were studied with positron emission tomography (PET) using 2-deoxy-2-[F-18]fluoro-D-glucose (F-18DG). Cases of retroperitoneal fibrosis and sclerosing peritonitis showed low F-18DG uptake with the mass/muscle radioactivity (M/M) ratio 2.0 and 1.9, respectively. A case of para...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199205000-00002

    authors: Kubota K,Yamada K,Yoshioka S,Yamada S,Ito M,Ido T

    更新日期:1992-05-01 00:00:00

  • Propionibacterium acnes Pacemaker Endocarditis in a Patient With a Redundant Loop of the Ventricular Lead: PET/CT Findings.

    abstract::A 59-year-old man with a pacemaker who was admitted for evaluation of fever was found to have a redundant loop of the ventricular lead and a vegetation attached to it. An FDG PET/CT revealed a focus of FDG uptake at the ventricular lead loop. Surgical extraction of the pacemaker device confirmed a Propionibacterium ac...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002686

    authors: Gorospe L,Miguelena-Hycka J,Martín-García M,Ajuria-Illarramendi O,Almeida-Aróstegui NA

    更新日期:2020-01-01 00:00:00

  • Cavernosal Metastasis From Prostate Cancer on 18F-Fluciclovine PET/CT.

    abstract::Uncommon penile metastasis from prostate cancer has been reported on PET/CT imaging with F-FDG, F-fluorocholine, C-choline, and Ga-PSMA. The author presents an additional case of F-fluciclovine PET/CT depiction of proximal and distal cavernosal metastases from prostate cancer with corresponding contrast-enhanced CT fi...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000003116

    authors: Nguyen BD

    更新日期:2020-10-01 00:00:00

  • FDG PET/CT in Carcinoma of the Tongue With Bilateral Adrenal Metastases.

    abstract::Squamous cell carcinoma is the most common malignant neoplasm of the oral cavity, and it contributes approximately 90% of all oral malignancies. We present a case of a squamous cell carcinoma of the tongue with rare site of bilateral adrenal metastases on F-FDG PET/CT with response evaluation after chemotherapy. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001521

    authors: Agarwal KK,Parida GK,Tripathi M,Sahoo MK,Thakar A,Bal CS,Kumar R

    更新日期:2017-02-01 00:00:00

  • Prediction of Overall Survival Based on Isocitrate Dehydrogenase 1 Mutation and 18F-FDG Uptake on PET/CT in Patients With Cerebral Gliomas.

    abstract:PURPOSE:This retrospective study aimed to correlate F-FDG uptake on PET/CT with isocitrate dehydrogenase enzyme isoform 1 (IDH1) mutation in patients with cerebral gliomas. Hierarchical interactions between factors affecting overall survival (OS) were also examined. METHODS:In 59 patients with glioma, the ratio of the...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002006

    authors: Kim D,Kim S,Kim SH,Chang JH,Yun M

    更新日期:2018-05-01 00:00:00

  • Diagnosis of Menètrier's disease with Tc-99m human serum albumin scintigraphy.

    abstract::Technetium-99m labeled human serum albumin has been shown to detect protein leakage into the bowel. A case of a young adult is presented with endoscopic and pathological correlation of scintigraphic findings supporting Menètrier's disease. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199502000-00004

    authors: Pacheco EJ,Moreno AJ,Ramos A,Murray R,Turnbull GL,Barzey A

    更新日期:1995-02-01 00:00:00

  • Diagnosis of uveo-parotid fever by 67Ga-citrate imaging.

    abstract::67Ga-citrate scan from skull to mid-abdomen showed increased uptake in both parotid glands, mediastinum, lungs, uvei and/or enlarged lacrimal glands. The differential diagnosis of the positive radiogallium scan is discussed with emphasis on the value of the extrathoracic findings. Tissue diagnosis confirmed the imagin...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197804000-00001

    authors: Oren VO,Uszler JM,White J

    更新日期:1978-04-01 00:00:00

  • Discordant uptake of technetium-99m DISIDA and technetium-99m sulfur colloid in an amebic abscess.

    abstract::Hepatobiliary imaging in a patient with an amebic abscess showed an early cold defect that later showed rim enhancement. A Tc-99m SC scan did not show prominent flow (making hepatoma unlikely) and showed the previously noted defect to appear larger and without rim enhancement. The differential damage to Kupffer cells ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198802000-00011

    authors: Allard JC,Lee VW,Foster J

    更新日期:1988-02-01 00:00:00

  • Benign cystic mesothelioma: false-positive iodine accumulation in a patient with oncocytic follicular thyroid carcinoma.

    abstract::Whole-body (131I) scintigraphy (WBS) is used to detect residual or metastatic tissue during treatment of differentiated thyroid carcinoma in combination with thyroglobulin (Tg) and ultrasonography of the neck. It is a highly sensitive method, but there is a high rate of false positives. We report the case of a 52-year...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182a75664

    authors: Meyer M,Godbert Y,Soubeyran I,Cazeau AL,Bonichon F

    更新日期:2014-09-01 00:00:00

  • Tc-99m MIBI scintigraphy in a patient with primary and metastatic malignant melanoma.

    abstract::Malignant melanoma is a rare malignant tumor arising within the melanocytes of the skin. The authors report a case of primary and metastatic malignant melanoma revealed with Tc-99m MIBI in one patient. Tc-99m MIBI images showed uptake in possible malignant melanoma skin lesions of the left calf and great toe of a 73-y...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-200205000-00008

    authors: Jang Kim S,Won Seok J,Ju Kim I,Ki Kim Y

    更新日期:2002-05-01 00:00:00

  • Quality and Safety in Healthcare, Part LXI: Burnout and Wellness in Residents.

    abstract::Some of the causes for resident burnout and other impairments of wellness are the same as for other physicians, but some are quite different. For example, residents have much less autonomy and control, are under more pressure to learn a huge amount of information quickly, are more frequently evaluated, have stress fro...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002886

    authors: Harolds JA

    更新日期:2020-09-01 00:00:00

  • FDG PET/CT Findings of Recurrent Respiratory Papillomatosis With Malignant Degeneration in the Lung.

    abstract::Recurrent respiratory papillomatosis is a rare benign disease caused by HPV-6 or HPV-11. The tumors may rarely undergo malignant degeneration. We performed FDG PET/CT in a patient experiencing recurrent respiratory papillomatosis who had pulmonary involvement. Although squamous cell carcinoma was detected in one of th...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000895

    authors: Tatci E,Gokcek A,Unsal E,Cimen F,Demirag F,Yazici S,Ozmen O

    更新日期:2015-10-01 00:00:00

  • Clinical Evaluation of 18F-PI-2620 as a Potent PET Radiotracer Imaging Tau Protein in Alzheimer Disease and Other Neurodegenerative Diseases Compared With 18F-THK-5351.

    abstract:PURPOSE:PET is a useful tool for detecting the presence and extent of brain tau accumulation. However, most first-generation tau PET tracers are limited for high off-target binding and detection of tau in non-Alzheimer disease (AD). This study evaluated potential clinical applications of F-PI-2620 as a novel PET tracer...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000003261

    authors: Oh M,Oh SJ,Lee SJ,Oh JS,Roh JH,Chung SJ,Lee JH,Lee CS,Kim JS

    更新日期:2020-11-01 00:00:00

  • Effect of dietary intake before F-18 FDG positron emission tomographic scanning on the evaluation of a solitary pulmonary nodule.

    abstract::The uptake of fluorine-18 fluorodeoxyglucose (F-18 FDG) by a malignant tumor depends on the blood glucose level. The authors present a striking case that illustrates the importance of blood glucose measurement in F-18 FDG positron emission tomographic (PET) imaging in a patient with a solitary pulmonary nodule. With t...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-200111000-00002

    authors: Ojha B,Bartley SC,Gundlapalli S,Mountz JM

    更新日期:2001-11-01 00:00:00

  • 18F-FDG PET for diagnosis and response assessment for aggressive NK cell leukemia.

    abstract::Aggressive natural killer cell leukemia (ANKL) is a rare malignant disorder of mature NK cells characterized by aggressive clinical course and poor outcome. The commonly involved sites are peripheral blood, bone marrow, liver, and spleen, but any organ can show involvement. We report a case of ANKL diagnosed and asses...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182952976

    authors: Park JA

    更新日期:2014-04-01 00:00:00

  • Assessing Cutaneous Psoriasis Activity Using FDG-PET: Nonattenuation Corrected Versus Attenuation Corrected PET Images.

    abstract::Psoriasis is a chronic inflammatory skin condition characterized by well-circumscribed erythematous plaques with thick silvery scale. Infiltration of inflammatory cells such as lymphocytes, neutrophils, and macrophages and epidermal cell proliferation within psoriatic lesions may result in selective FDG accumulation. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000851

    authors: Bakshi A,Gholami S,Alavi A,Gelfand JM,Takeshita J

    更新日期:2015-09-01 00:00:00

  • Radionuclide imaging of primary tumors and tumor-like conditions of the liver.

    abstract::The unique information provided by radionuclide techniques allows the noninvasive characterization of primary tumors and tumor-like conditions of the liver. A thorough knowledge of the mechanisms of radiopharmaceutical localization and the histologic abnormalities present in each condition is required to optimally use...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198707000-00022

    authors: Drane WE,Krasicky GA,Johnson DA

    更新日期:1987-07-01 00:00:00

  • Richter Syndrome Presenting With Colon Localization.

    abstract::A 75-year-old man, who had been diagnosed with small lymphocytic lymphoma with cervical localization, underwent F-FDG PET/CT with iodinated contrast medium due to the appearance of cervical swelling suspected of illness relapse. PET/CT revealed intense F-FDG uptake in multiple cervical and subdiaphragmatic lymph nodes...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002393

    authors: Lavalle M,Minordi LM,Hohaus S,Manfredi R,Rufini V

    更新日期:2019-02-01 00:00:00

  • Tumor and therapy associated abnormal changes on bone scintigraphy. Old and new phenomena.

    abstract::Bone scintigraphy is very sensitive in detecting metastases in an early stage, when changes in osteoblast function precede morphologic changes. In many oncologic situations, however, osteoarticular abnormal changes seen on the bone scan are not caused by tumor infiltration. They may be due to tumor associated conditio...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00003072-199310000-00001

    authors: Stokkel MP,Valdés Olmos RA,Hoefnagel CA,Richel DJ

    更新日期:1993-10-01 00:00:00

  • 18F-FDG PET/CT for staging and detection of extramedullary organ involvement in chronic myelomonocytic leukemia.

    abstract::Chronic myelomonocytic leukemia (CMML) is a rare hematologic malignancy characterized by the accumulation of monocytes in the blood and bone marrow, dysplastic hematopoiesis, and potential leukemic involvement of organs. We report a case of leukemic involvement of cervical lymph nodes detected by 18F-FDG PET/CT. A 53-...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182a77c99

    authors: Derlin T,Clauditz TS,Bannas P

    更新日期:2014-09-01 00:00:00

  • Transient left ventricular dilatation in the absence of epicardial disease on angiography.

    abstract::A 58-year-old woman with a previous anterior myocardial infarction, recurrent chest pain, transient adenosine-induced left ventricular dilatation but no apparent epicardial disease on angiography is presented. Transient ischemic dilatation during myocardial perfusion imaging, and the reported causes of transient left ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.rlu.0000127088.20310.d0

    authors: Choong KK,Russell PA

    更新日期:2004-06-01 00:00:00

  • Estimation of Tc-99m MAG3 clearance using camera-based methods without blood sampling.

    abstract:PURPOSE:To establish camera-based methods for estimating Tc-99m mercaptoacetyltriglycine (MAG3) clearance without blood sampling. MATERIALS AND METHODS:The results of renal scintigraphy with Tc-99m MAG3 obtained from 160 patients were analyzed retrospectively. Eight renogram parameters were calculated for each patient...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e31821a2a96

    authors: Inoue Y,Ohtomo K

    更新日期:2011-11-01 00:00:00

  • 18F-Fluciclovine-Avid Mediastinal Lymph Node Metastasis of Cutaneous Malignant Melanoma.

    abstract:ABSTRACT:A 63-year-old man with recent diagnosis of high-risk prostate adenocarcinoma was referred to our Nuclear Medicine Department for 18F-fluciclovine PET/CT to rule out metastasis in the setting of elevated serum prostate-specific antigen levels. The patient had previous history of nodular melanoma of the right ch...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000003319

    authors: Shariftabrizi A,Pillenahalli Maheshwarappa R,Kahn D,Pollard J

    更新日期:2021-02-01 00:00:00

  • Pseudo-Budd-Chiari syndrome.

    abstract::A patient with clinical, laboratory, radiographic and scintigraphic findings resembling the Budd-Chiari syndrome is described. However, at autopsy there was no thrombotic occlusion of any of the intrahepatic veins. The right hepatic vein was completely constricted by the hypertrophied left lobe of the liver, and the l...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197801000-00009

    authors: Dhawan VM,Sziklas JJ,Spencer RP

    更新日期:1978-01-01 00:00:00

  • Radionuclide angiography in suspected acute cholecystitis: further observations.

    abstract::Radionuclide angiography (RNA) and cholescintigraphy were performed prospectively in 300 patients with suspected acute cholecystitis (AC). Of 79 patients with positive RNA, 63 had AC (80%). Positive RNA was seen in 23 of 26 cases with gangrenous AC (88%) while 12 of the 26 had a positive "rim" sign (46%). All 12 patie...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198912000-00001

    authors: Colletti PM,Cirimelli KM,Radin DR,Chandrasoma P,Ralls PW,Siegel ME

    更新日期:1989-12-01 00:00:00

  • Tracheobronchomalacia incidentally detected on Tc-99m ventilation/perfusion SPECT.

    abstract::A Tc-99m Technegas MAA-SPECT was performed on an 81-year-old woman to exclude pulmonary embolism. It showed hypoperfusion and practically absent ventilation of the entire left lung, suggesting a left-sided centrally localized airway obstruction or compression with secondary hypoxic vasoconstriction. Subsequent broncho...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3181b06bea

    authors: Deryk S,Nieboer K,Ceulemans G,Bossuyt A,Vanhove C,Everaert H

    更新日期:2009-09-01 00:00:00

  • 180 degrees SPECT of the spine in patients with low back pain. Comparison with 360 degrees acquisition.

    abstract::Single-photon emission computed tomography has been proven to detect more abnormalities than planar bone scintigraphy in patients with low back pain (LBP). Both 180 degrees and 360 degrees acquisitions were performed in 24 patients with LBP to determine whether the shorter 180 degrees posterior SPECT is as accurate fo...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199306000-00004

    authors: Even-Sapir E,Barnes DC,Iles SE,Nickerson RC

    更新日期:1993-06-01 00:00:00

  • A new thrombus imaging agent. Human recombinant fibrin binding domain labeled with In-111.

    abstract::The amino-terminal domain of fibronectin has a fibrin binding site and a site for covalent cross-linking to fibrin. This fibrin binding domain was isolated from human recombinant fibronectin and labeled with In-111; the final molecular weight was 12 kD. It was applied to a pilot study of 62 patients; 30 who were thoug...

    journal_title:Clinical nuclear medicine

    pub_type: 临床试验,杂志文章

    doi:10.1097/00003072-199505000-00004

    authors: Rosenthall L,Leclerc J

    更新日期:1995-05-01 00:00:00