Long-term adaptation to prism-induced inversion of the retinal images.

Abstract:

:For 1 week, healthy human participants ( n=7) were devoid of normal vision by exposure to prism lenses that optically rotated their perceived world around the line of sight by 180 degrees. Adaptation to such prisms involved sustained and vigorous practice of the ability to redirect the unadapted efferent motor command; because prior to all visually guided movements, the to-be-executed efferent command was based on incorrect (prismatically reversed) spatial information. The time course of this sort of adaptation was systematically explored in Cooper-Shepard mental rotation (MR) tests and in naturalistic motor-tasks for the purpose of investigating whether mental rotations of the direction of the intended movement share common aspects with the process of MR. A control group ( n=7) intermittently exposed to the distorted spatial organization of the central visual field was studied in parallel. The main results were as follows: (a) the MR reaction times (RTs) day 1 with prisms appeared to be very similar to the normal RTs (day 1, no-prisms) with the one exception that subjects now responded within a prism (rotated) frame of spatial reference rather than within the environmentally upright. The visuomotor performance became grossly irregular and dysmetric. (b) The majority of the visuomotor adaptation functions began to level off on the 3rd day. (c) The increases in natural motor proficiency were accompanied by a systematic and noticeable decrease in magnitude of the MR Y-intercept obtained from the linear regression line calculated between each subject's RT and the various stimulus angles. MR slopes were stable through days 1-7 for both the experimental and control group. An increased correlation between rotational stimulus angle and RT suggested that the MR function also became progressively more tightly coupled to the stimulus angles. (d) Postadaptation measures of performance indicated the occurrence of selective and minimal adaptation in the natural motor tasks only. It is suggested that these results reflect an improved attentional (strategic) ability to replace incorrect (error producing) control signals with correct (error reducing) control signals. As a result, perceptual-motor start-up processes directly related to spatial coding and to the planning, initiation and correction of the intended direction of motor-or-mental movement improved while the subprocess ("stage") concerned with transformations of such movements remained unchanged. Visuomotor adaptation to inverting prisms engages, and thereby stimulates, a cortical system also invoked in the preparatory process of MR.

journal_name

Exp Brain Res

authors

Richter H,Magnusson S,Imamura K,Fredrikson M,Okura M,Watanabe Y,Långström B

doi

10.1007/s00221-002-1097-6

keywords:

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

445-57

issue

4

eissn

0014-4819

issn

1432-1106

journal_volume

144

pub_type

杂志文章
  • Spatial-temporal interactions in the human brain.

    abstract::The review summarises current evidence on the cognitive mechanisms for the integration of spatial and temporal representations and of common brain structures to process the where and when of stimuli. Psychophysical experiments document the presence of spatially localised distortions of sub-second time intervals and su...

    journal_title:Experimental brain research

    pub_type: 杂志文章,评审

    doi:10.1007/s00221-009-1834-1

    authors: Oliveri M,Koch G,Caltagirone C

    更新日期:2009-06-01 00:00:00

  • Changes in corticospinal excitability evoked by common peroneal nerve stimulation depend on stimulation frequency.

    abstract::The afferent volley generated during neuromuscular electrical stimulation (NMES) can increase the excitability of the human corticospinal (CS) pathway. This study was designed to determine the effect of different frequencies of NMES applied over the common peroneal nerve on changes in CS excitability for the tibialis ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-010-2202-x

    authors: Mang CS,Lagerquist O,Collins DF

    更新日期:2010-05-01 00:00:00

  • Production of finely graded forces in humans: effects of simulated weightlessness by water immersion.

    abstract::We have shown before that subjects exposed to a changed gravitoinertial environment produce exaggerated manual forces. From the observed pattern of findings, we argued that initial forces were exaggerated because of abnormal vestibular activity and peak forces because of degraded proprioceptive feedback. If so, only p...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-012-2999-6

    authors: Dalecki M,Dräger T,Mierau A,Bock O

    更新日期:2012-04-01 00:00:00

  • Temporal, regional and cellular selectivity of neonatal alteration of the thyroid state on neurochemical maturation in the rat.

    abstract::The effects of alteration of thyroid state on neurochemical maturation have been studied in rats made hypothyroid by daily injections of methimazole or hyperthyroid by daily supplementation with thyroid hormone (T3) from postnatal days 1 to 27. Biochemical assays on seven brain regions plus the spinal cord were carrie...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00229834

    authors: Virgili M,Saverino O,Vaccari M,Barnabei O,Contestabile A

    更新日期:1991-01-01 00:00:00

  • Diencephalic connections of the superior colliculus in the hedgehog tenrec.

    abstract::Using different tracer substances the pathways connecting the superior colliculus with the diencephalon were studied in the Madagascan hedgehog tenrec (Echinops telfairi), a nocturnal insectivore with tiny eyes, a small and little differentiated superior colliculus and a visual cortex with no obvious fourth granular l...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00228725

    authors: Künzle H

    更新日期:1996-10-01 00:00:00

  • Direct retinal projections of the "non-image forming" system to the hypothalamus, anterodorsal thalamus and basal telencephalon of mink (Mustela vison) brain.

    abstract::The retinal projections of the "non-image forming" system to the hypothalamus, anterodorsal thalamus and basal telencephalon were visualized in adult mink using the anterograde transport of cholera toxin conjugated to horseradish peroxidase injected intraocularly. A major and nearly symmetrical bilateral input of labe...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00228253

    authors: Martinet L,Servière J,Peytevin J

    更新日期:1992-01-01 00:00:00

  • Effects of sensory deprivation upon a single cortical vibrissal column: a 2DG study.

    abstract::Effects of sensory deprivation upon ability of a vibrissa to activate a functional column in the barrel field of somatosensory cortex were examined with 2 deoxyglucose (2DG) autoradiography in the rat. After six weeks of whisker plucking started at birth, and one week of recovery, the cortical column activated by the ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00230950

    authors: Kossut M

    更新日期:1992-01-01 00:00:00

  • Arm movement metrics influence saccade metrics when looking and pointing towards a memorized target location.

    abstract::Saccades are known to influence subsequent arm movements. There is less information to suggest that the characteristics of saccades depend on the reaching movements they accompany. To explore this issue, we studied the systematic errors of saccades generated by two adult female Rhesus monkeys (Macaca Mulata), which we...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-008-1427-4

    authors: Kattoulas E,Smyrnis N,Mantas A,Evdokimidis I,Raos V,Moschovakis A

    更新日期:2008-08-01 00:00:00

  • Influence of opioids and naloxone on rhythmic motor activity in spinal cats.

    abstract::The effects of L-DOPA, naloxone, and the opioids (D-Ala2,N-Me-Phe4,Gly5-ol)-enkephalin (DAGO) and D-Ser2-Leu-enkephalin-Thr6 (DSLET) on spinal motor rhythm generation were compared in anemically decapitated high spinal cats. After premedication with nialamide, DOPA caused the well-known, slow rhythmic motor activity w...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00241493

    authors: Schomburg ED,Steffens H

    更新日期:1995-01-01 00:00:00

  • Kinaesthetic neurons in thalamus of humans with and without tremor.

    abstract::Increased afferent input may alter receptive field sizes, properties and somatotopographic representation in the cortex. Changes in the motor thalamus may also occur as a result of altered afferent input. Such plasticity has been implicated in both sensory and movement disorders. Using tremor as a model of augmented a...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-003-1399-3

    authors: Kiss ZH,Davis KD,Tasker RR,Lozano AM,Hu B,Dostrovsky JO

    更新日期:2003-05-01 00:00:00

  • Temporal discrimination in the cerebellar cortex during conditioned eyelid responses.

    abstract::Little is known about mechanisms used by the nervous system to encode time. In light of recent evidence, cerebellar cortex involvement in the learned timing of conditioned eyelid responses shows promise as an area of investigation into neural timing mechanisms. Lesion studies indicate that the cerebellar cortex is nec...

    journal_title:Experimental brain research

    pub_type: 杂志文章,评审

    doi:10.1007/s002210050443

    authors: Perrett SP

    更新日期:1998-07-01 00:00:00

  • Pathological and experimentally induced blindness induces auditory activity in the cat primary visual cortex.

    abstract::Early blindness in humans and experimental visual deprivation in animal models are known to induce compensatory somatosensory and/or auditory activation of the visual cortex. An abnormal hydrocephalic cat with extreme malformation of the visual system, born in our breeding colony, rendered a good model system for inve...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s002219900295

    authors: Yaka R,Yinon U,Rosner M,Wollberg Z

    更新日期:2000-03-01 00:00:00

  • The effect of agonist/antagonist muscle vibration on human position sense.

    abstract::During voluntary movement, muscle spindles of both the agonist and antagonist muscles potentially can supply information about position of the limb. Muscle vibration is known to increase muscle spindle discharge and cause systematic distortions of limb position sense in humans. The following two experiments attempted ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF02423506

    authors: Inglis JT,Frank JS

    更新日期:1990-01-01 00:00:00

  • Relation of activity in precentral cortical neurons to force and rate of force change during isometric contractions of finger muscles.

    abstract::The activity of single neurons within the hand area of the precentral motor cortex of primates was recorded during the performance of a maintained precision grip between the thumb and forefinger. The finger opposition forces were exerted against a strain gauge which allowed force changes to be studied under near isome...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00239743

    authors: Smith AM,Hepp-Reymond MC,Wyss UR

    更新日期:1975-09-29 00:00:00

  • Two populations of glial cells from fish optic nerve/tract with distinct electrophysiological properties.

    abstract::The electrophysiological properties of the two major glial cell types in cultures from the regenerating goldfish optic nerve/tract were studied with patch-clamp techniques. Spindle-shaped cells express myelin proteins. These oligodendrocyte-like cells possess outwardly rectifying currents, do not show glutamate activa...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00231855

    authors: Hoppe D,Bastmeyer M,von Blankenfeld G,Kettenmann H,Stuermer CA

    更新日期:1991-01-01 00:00:00

  • Effect of testosterone and the oestrous cycle on neuronal refractory periods and firing rates of stria terminalis neurones in the female rat.

    abstract::Absolute refractory periods of a subpopulation of corticomedial amygdala (CMA) neurones which project to the medial preoptic/anterior hypothalamic junction (MPH) via the stria terminalis were recorded in the female rat. Previous experiments have shown that this sub-population of CMA neurones is testosterone-sensitive ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00236571

    authors: Kendrick KM

    更新日期:1981-01-01 00:00:00

  • Reflexes induced by nerve stimulation in walking cats with implanted cuff electrodes.

    abstract::Neural cuffs, implanted around various hindlimb nerves (sural, common peroneal, posterior tibial), were used to deliver brief stimulus trains to unrestrained cats walking on a treadmill. The resulting perturbations of the step cycle were evaluated by analyzing the EMG bursts recorded from the ankle extensors and by hi...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00239728

    authors: Duysens J,Stein RB

    更新日期:1978-06-19 00:00:00

  • On the link between action planning and motor imagery: a developmental study.

    abstract::We examined the link between action planning and motor imagery in 6- and 8-year-old children. Action planning efficiency was assessed with a bar transport task. Motor imagery and visual imagery abilities were measured using a hand mental rotation task and a number (i.e., non-body stimuli) mental rotation task, respect...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-013-3698-7

    authors: Toussaint L,Tahej PK,Thibaut JP,Possamai CA,Badets A

    更新日期:2013-11-01 00:00:00

  • REM theta activity enhances inhibitory control in typically developing children but not children with ADHD symptoms.

    abstract::Sleep disturbances impair cognitive functioning in typically developing populations. Children with attention-deficit/hyperactivity disorder (ADHD), a disorder characterized by impaired inhibitory control and attention, commonly experience sleep disturbances. Whether inhibitory impairments are related to sleep deficits...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-017-4906-7

    authors: Cremone A,Lugo-Candelas CI,Harvey EA,McDermott JM,Spencer RM

    更新日期:2017-05-01 00:00:00

  • Neuroplasticity of imagined wrist actions after spinal cord injury: a pilot study.

    abstract::Motor imagery (MI - i.e., the mental representation of an action without physically executing it) stimulates brain motor networks and promotes motor learning after spinal cord injury (SCI). An interesting issue is whether the brain networks controlling MI are being reorganized with reference to spared motor functions....

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-014-4114-7

    authors: Di Rienzo F,Guillot A,Mateo S,Daligault S,Delpuech C,Rode G,Collet C

    更新日期:2015-01-01 00:00:00

  • Effects of delayed auditory and visual feedback on sequence production.

    abstract::This study represents the first systematic comparison of the relative contributions of auditory and visual feedback to sequence production. Participants learned an isochronous melody that they performed on a keyboard and attempted to perform this sequence at a prescribed rate while auditory and visual feedback were ma...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-012-3289-z

    authors: Kulpa JD,Pfordresher PQ

    更新日期:2013-01-01 00:00:00

  • Models of behaviors when detecting displacements of joints.

    abstract::This report describes two models of human behavior when detecting displacements of joints that allow one to compare and integrate findings from different proprioception tests in a quantitative way. Results from various tests have led to different and often conflicting conclusions about proprioceptive behaviors and the...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00227954

    authors: Clark FJ,Deffenbacher KA

    更新日期:1996-12-01 00:00:00

  • Spatial properties of binocular neurones in the human visual system.

    abstract::The spatial properties of human binocular mechanisms were investigated using the technique of subthreshold summation. Isolation of binocular mechanisms was achieved by means of interocular stimulus presentation. The contrast detection threshold for a sinusoidal test grating viewed by one eye was found to be reduced by...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00237700

    authors: Blake R,Levinson E

    更新日期:1977-02-16 00:00:00

  • Cutaneomotor integration in humans is somatotopically organized at various levels of the nervous system and is task dependent.

    abstract::Integration of tactile afferent signals with motor commands is crucial for the performance of purposeful movements such as during manipulation of an object in the hand. To study the somatotopic organization of sensorimotor integration we applied electrical peripheral conditioning stimuli to a digit located near (homot...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s002210050005

    authors: Classen J,Steinfelder B,Liepert J,Stefan K,Celnik P,Cohen LG,Hess A,Kunesch E,Chen R,Benecke R,Hallett M

    更新日期:2000-01-01 00:00:00

  • Inhibition of return in children with attention deficit hyperactivity disorder.

    abstract::Earlier studies have suggested an impairment in the attention and eye movement control of children with ADHD. An important phenomenon in the control of attentional shifts and eye movements is the inhibition of return (IOR), which states that our brain works in a way that prevents our attention from returning to a spat...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-002-1362-8

    authors: Li CS,Chang HL,Lin SC

    更新日期:2003-03-01 00:00:00

  • An electrophysiological study of task demands on concreteness effects: evidence for dual coding theory.

    abstract::We examined ERP responses during the generation of word associates or mental images in response to concrete and abstract concepts. Of interest were the predictions of dual coding theory (DCT), which proposes that processing lexical concepts depends on functionally independent but interconnected verbal and nonverbal sy...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-011-2734-8

    authors: Welcome SE,Paivio A,McRae K,Joanisse MF

    更新日期:2011-07-01 00:00:00

  • Ultrastructural observations of efferent terminals in the crista ampullaris of the toadfish, Opsanus tau.

    abstract::The present study was conducted to visualize the ultrastructural features of vestibular efferent boutons in the oyster toadfish, Opsanus tau. The crista ampullaris of the horizontal semicircular canal was processed for and examined by routine transmission electron microscopy. The results demonstrate that such boutons ...

    journal_title:Experimental brain research

    pub_type: 更正并重新发布的文章,杂志文章

    doi:10.1007/s00221-004-1898-x

    authors: Holstein GR,Martinelli GP,Boyle R,Rabbitt RD,Highstein SM

    更新日期:2004-07-01 00:00:00

  • Static and dynamic discharge properties of vestibular-nerve afferents in the mouse are affected by core body temperature.

    abstract::The goal of this study was to determine the effect of changes in core body temperature on the resting discharge rate and sensitivity of vestibular-nerve afferents. Extracellular recordings were made from vestibular-nerve afferents innervating the semicircular canals in anesthetized C57BL/6 mice maintained at a core bo...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-009-2015-y

    authors: Park HJ,Lasker DM,Minor LB

    更新日期:2010-01-01 00:00:00

  • Modulation of locomotor activity in complete spinal cord injury.

    abstract::The aim of this study was to evaluate the modulation of muscle activity during locomotor-like movements by different walking speeds in subjects with a motor complete spinal cord injury (SCI) compared to actively--and passively-walking control subjects without neurological deficit. Stepping movements on a treadmill wer...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-006-0509-4

    authors: Lünenburger L,Bolliger M,Czell D,Müller R,Dietz V

    更新日期:2006-10-01 00:00:00

  • Bilateral projections from the parabigeminal nucleus to the superior colliculus in monkey.

    abstract::We examined the distribution of labeled neurons in the parabigeminal nucleus of the monkey following injections of retrograde fluorescent tracers into the superior colliculus. The extent of the visual field representation included in the injection site was assessed from the location of labeled cells in striate cortex....

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00230521

    authors: Baizer JS,Whitney JF,Bender DB

    更新日期:1991-01-01 00:00:00