Abstract：
:In this study we combined event-related fMRI with a parametric manipulation of the go nogo paradigm to examine the effect of preceding context on inhibitory processes. Nogo trials were preceded by either 1, 3, or 5 go trials and then compared to one another. Two distinct patterns of activation were associated with behavioral inhibition: First, the ventral prefrontal cortex, cingulate gyrus, and superior parietal regions showed a context effect with an increase in MR signal to nogo trials with increasing number of preceding go trials. Second, anterior regions in the supplementary and premotor cortex showed an increase in MR signal on the nogo condition after 5 preceding go trials, but not after only 1 or 3. A model using the BOLD response in our data was used to verify that the effect of context was not an artifact of the randomization scheme used in the design.
journal_name
Neuroimagejournal_title
NeuroImageauthors
Durston S,Thomas KM,Worden MS,Yang Y,Casey BJdoi
10.1006/nimg.2002.1074keywords:
subject
Has Abstractpub_date
2002-06-01 00:00:00pages
449-53issue
2eissn
1053-8119issn
1095-9572pii
S1053811902910748journal_volume
16pub_type
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