Role of AMP-activated protein kinase in the regulation of gene transcription.


:AMP-activated protein kinase (AMPK) is a regulator of cellular metabolism in response to changes in the energy status of the cells. AMPK was known to shut down energy-consuming pathways in response to a fall in the ATP/AMP ratio by phosphorylating key enzymes of intermediate metabolism. Here we will discuss the recent evidence implicating AMPK in the regulation of gene expression in mammals, mainly in the liver and in the pancreatic beta-cells.


Biochem Soc Trans


Leclerc I,Viollet B,da Silva Xavier G,Kahn A,Rutter GA





Has Abstract


2002-04-01 00:00:00












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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Seidler A,Jaschkowitz K,Wollenberg M

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    journal_title:Biochemical Society transactions

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    authors: Hall MN

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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Márquez V,Wilson DN,Nierhaus KH

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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Sánchez C,Cabrera JJ,Gates AJ,Bedmar EJ,Richardson DJ,Delgado MJ

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    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章


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    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章


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    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Cryle MJ

    更新日期:2010-08-01 00:00:00

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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Koch S

    更新日期:2012-02-01 00:00:00

  • Recent structural studies of RNA polymerases II and III.

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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Cramer P

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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Leitgeb S,Nidetzky B

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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Sun B,Ito T

    更新日期:2010-04-01 00:00:00

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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Krapp A,Simanis V

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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


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    journal_title:Biochemical Society transactions

    pub_type: 杂志文章,评审


    authors: Reuber TL,Reed J,Glazebrook J,Glucksmann MA,Ahmann D,Marra A,Walker GC

    更新日期:1991-08-01 00:00:00