Abstract:
:AMP-activated protein kinase (AMPK) is a regulator of cellular metabolism in response to changes in the energy status of the cells. AMPK was known to shut down energy-consuming pathways in response to a fall in the ATP/AMP ratio by phosphorylating key enzymes of intermediate metabolism. Here we will discuss the recent evidence implicating AMPK in the regulation of gene expression in mammals, mainly in the liver and in the pancreatic beta-cells.
journal_name
Biochem Soc Transjournal_title
Biochemical Society transactionsauthors
Leclerc I,Viollet B,da Silva Xavier G,Kahn A,Rutter GAdoi
10.1042/keywords:
subject
Has Abstractpub_date
2002-04-01 00:00:00pages
307-11issue
2eissn
0300-5127issn
1470-8752journal_volume
30pub_type
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