Abstract:
:IscA homologs are known to be involved in iron-sulfur cluster formation in various organisms. Recombinant proteins of two IscA homologs from the cyanobacterium Synechocystis PCC 6803, designated SLR1417 and SLR1565, were purified. The absorption spectrum of purified SLR1565 was typical for [2Fe-2S] cluster-containing proteins, whereas that of SLR1417 predominantly showed the presence of the iron ion alone. In the cyanobacterial cell extracts, only SLR1565 was found to form a complex with a novel prokaryotic HEAT-repeats-containing protein, SLR1098. Thus, the two cyanobacterial IscA protein homologs exist in distinct molecular states, suggesting different cellular roles for these proteins.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Morimoto K,Nishio K,Nakai Mdoi
10.1016/s0014-5793(02)02736-9keywords:
subject
Has Abstractpub_date
2002-05-22 00:00:00pages
123-7issue
1-3eissn
0014-5793issn
1873-3468pii
S0014579302027369journal_volume
519pub_type
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