Overexpression of hyaluronan synthase-2 reduces the tumorigenic potential of glioma cells lacking hyaluronidase activity.

abstract：OBJECTIVE:To test the spatial accuracy of coordinates generated from magnetic resonance imaging (MRI) scans, using the Brown-Roberts-Wells head frame and localizer system (Radionics, Inc., Burlington, MA). METHODS:An anthropomorphic head phantom, consisting of a two-dimensional lattice of acrylic spheres (4-mm diamete...

journal_title：Neurosurgery

authors： Orth RC,Sinha P,Madsen EL,Frank G,Korosec FR,Mackie TR,Mehta MP

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Flow-diverting stents offer a promising treatment option for complex aneurysms. OBJECTIVE:To evaluate the safety and efficacy of the Pipeline embolization device (PED) in the treatment of fusiform and dissecting aneurysms. METHODS:Sixty-five consecutive patients with 69 fusiform and dissecting aneurysms un...

journal_title：Neurosurgery

authors： Fischer S,Perez MA,Kurre W,Albes G,Bäzner H,Henkes H

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:In order to weigh the risks of surgery against the presumed advantages, it is important to have specific knowledge about complication rates. OBJECTIVE:To study the surgical mortality and rate of reoperations for hematomas and infections after intracranial surgery for brain tumors in a large, contemporary, s...

journal_title：Neurosurgery

authors： Lassen B,Helseth E,Rønning P,Scheie D,Johannesen TB,Mæhlen J,Langmoen IA,Meling TR

更新日期：2011-05-01 00:00:00

abstract：:Three patients with occlusive cerebrovascular disease were evaluated for possible extracranial-intracranial arterial anastomosis. Cerebral angiography repeated at a later date revealed disappearance of the initial vascular stenosis or occlusion and development of extensive collateral circulation. It was concluded in t...

journal_title：Neurosurgery

authors： Fox JL

更新日期：1978-05-01 00:00:00

abstract：:Neuroendovascular embolization represents a critical component of the multidisciplinary management of cerebral arteriovenous malformations. Safe and effective embolization may be performed only in the context of a well-designed, rational treatment plan that is fundamentally based on a clear understanding of the natura...

journal_title：Neurosurgery

authors： Fiorella D,Albuquerque FC,Woo HH,McDougall CG,Rasmussen PA

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:Evaluation of the safety and effectiveness of endovascular retreatment of intracranial aneurysms with detachable coils. METHODS:Retrospective analysis of clinical outcome as well as angiographic studies both before and after coil retreatment. The indication for retreatment was based on either inadequate occl...

journal_title：Neurosurgery

authors： Henkes H,Fischer S,Liebig T,Weber W,Reinartz J,Miloslavski E,Kühne D

更新日期：2008-06-01 00:00:00

abstract：OBJECTIVE:To describe a new endoscope shaft developed for suction-aspiration during endoscopic transsphenoidal pituitary surgery. METHODS:A custom-made shaft for a Wolf endoscope (Richard Wolf GmbH, Knittlingen, Germany) was developed with a height of 10 mm and a width of 5 mm, allowing an additional working channel f...

journal_title：Neurosurgery

authors： van Lindert EJ,Grotenhuis JA

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:A variety of imaging strategies may be used to derive reliable stereotactic coordinates when performing deep brain stimulation lead implants. No single technique has yet proved optimal. OBJECTIVE:To compare the relative accuracy of stereotactic coordinates for the subthalamic nucleus (STN) derived either fr...

journal_title：Neurosurgery

authors： Ben-Haim S,Gologorsky Y,Monahan A,Weisz D,Alterman RL

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:The goals of treating Koos grade IV vestibular schwannomas are to relieve brainstem compression, preserve or restore neurological function, and achieve long-term tumor control while minimizing tumor- and treatment-related morbidity. OBJECTIVE:To propose a treatment paradigm involving the intentional near-to...

journal_title：Neurosurgery

authors： Zumofen DW,Guffi T,Epple C,Westermann B,Krähenbühl AK,Zabka S,Taub E,Bodmer D,Mariani L

更新日期：2018-02-01 00:00:00

abstract：:Intracranial lipomas are uncommon and rarely symptomatic lesions accounting for 0.06 to 0.46% of intracranial lesions. The management of symptomatic dorsal brain stem lipomas was once limited to cerebrospinal fluid diversion, but with recent advances in microsurgery, they now may be directly treated. We report three p...

journal_title：Neurosurgery

authors： Baeesa SS,Higgins MJ,Ventureyra EC

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Minimally invasive surgery procedures, including stereotactic catheter aspiration and clearance of intracerebral hemorrhage (ICH) with recombinant tissue plasminogen activator hold a promise to improve outcome of supratentorial brain hemorrhage, a morbid and disabling type of stroke. A recently completed Pha...

journal_title：Neurosurgery

authors： Awad IA,Polster SP,Carrión-Penagos J,Thompson RE,Cao Y,Stadnik A,Money PL,Fam MD,Koskimäki J,Girard R,Lane K,McBee N,Ziai W,Hao Y,Dodd R,Carlson AP,Camarata PJ,Caron JL,Harrigan MR,Gregson BA,Mendelow AD,Zuccare

更新日期：2019-06-01 00:00:00

abstract：:From 1978 to 1988, 314 patients with malignant astrocytoma were treated by our neuro-oncology team. Twenty-five patients were excluded from further analysis because of a lack of adequate follow-up, the brain-stem location of the tumor, or an age of less than 18 years. Of the 289 remaining patients in the valid study g...

journal_title：Neurosurgery

authors： Salcman M,Scholtz H,Kaplan RS,Kulik S

更新日期：1994-02-01 00:00:00

abstract：IMPORTANCE:Rhinocerebral mucormycosis is extremely difficult to treat. Approximately 70% of patients are poorly controlled diabetics, and many of the remainder are immunocompromised as a consequence of cytotoxic drugs, burn injuries, or end-stage renal disease. Despite standard treatment consisting of surgical debridem...

journal_title：Neurosurgery

authors： Adler DE,Milhorat TH,Miller JI

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:A seasonal and meteorological influence on the incidence of spontaneous subarachnoid hemorrhage (SAH) has been suggested, but a consensus in the literature has yet to emerge. OBJECTIVE:This study examines the impact of weather patterns on the incidence of SAH using a geographically broad analysis of hospita...

journal_title：Neurosurgery

authors： Cowperthwaite MC,Burnett MG

更新日期：2011-01-01 00:00:00

abstract：:In an attempt to eliminate the many negative aspects of conventional extensive laminectomy, we originated in 1981 and have developed a new surgical technique called "suspension laminotomy." A basic principle of this operation is preservation and repair of the soft and bony tissue of the spine with osseous enlargement ...

journal_title：Neurosurgery

authors： Ohmori K,Ishida Y,Suzuki K

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:Resection of cerebellopontine angle (CPA) meningiomas may result in significant neurological morbidity. Radiosurgery offers a minimally invasive alternative to surgery. OBJECTIVE:To evaluate, in a multicenter cohort study, the outcomes of patients harboring CPA meningiomas who underwent Gamma Knife radiosur...

journal_title：Neurosurgery

authors： Ding D,Starke RM,Kano H,Nakaji P,Barnett GH,Mathieu D,Chiang V,Omay SB,Hess J,McBride HL,Honea N,Lee JY,Rahmathulla G,Evanoff WA,Alonso-Basanta M,Lunsford LD,Sheehan JP

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To review the natural history and determine the rates of intra- and extralesional hemorrhaging of brainstem cavernous malformations (cavernomas) monitored by one neuro-ophthalmology service. METHODS:A record review of all patients with brainstem cavernomas who were evaluated by a neuroophthalmology service b...

journal_title：Neurosurgery

authors： Kupersmith MJ,Kalish H,Epstein F,Yu G,Berenstein A,Woo H,Jafar J,Mandel G,De Lara F

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVE:To report our experience in treatment of arteriovenous malformations (AVMs) using a new liquid embolic agent, Onyx (Micro Therapeutics, Inc., Irvine, CA). METHODS:Between January 1998 and May 1999, 23 patients (8 men and 15 women) were treated. The patients' average age was 40 years, with seizure being the m...

journal_title：Neurosurgery

authors： Jahan R,Murayama Y,Gobin YP,Duckwiler GR,Vinters HV,Viñuela F

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Risk factors for poor quality of life (QOL) after subarachnoid hemorrhage (SAH) remain poorly described. OBJECTIVE:To identify the frequency and predictors of poor QOL 1 year after SAH. METHODS:We studied 1-year QOL in a prospectively collected cohort of 1181 consecutively admitted SAH survivors between Ju...

journal_title：Neurosurgery

authors： Taufique Z,May T,Meyers E,Falo C,Mayer SA,Agarwal S,Park S,Connolly ES,Claassen J,Schmidt JM

更新日期：2016-02-01 00:00:00

abstract：:The authors discuss the indications for both elective and emergency carotid endarterectomy. Reports on the surgical treatment of asymptomatic bruit and contralateral carotid stenosis are reviewed. The results of endarterectomy for symptomatic carotid disease, including transient ischemic attacks, acute neurological de...

journal_title：Neurosurgery

authors： Loftus CM,Quest DO

更新日期：1983-12-01 00:00:00

abstract：OBJECTIVE:Noninvasive observation of degenerating and regenerating peripheral nerves could improve the diagnosis and treatment of nerve injuries. We constructed a novel phased-array radiofrequency coil to permit magnetic resonance imaging (MRI) observation of the sciatic nerve and its target muscles in rats after injur...

journal_title：Neurosurgery

authors： Aagaard BD,Lazar DA,Lankerovich L,Andrus K,Hayes CE,Maravilla K,Kliot M

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:While high-resolution imaging is increasingly used in guiding decisions about surgical interventions for the treatment of trigeminal neuralgia, direct assessment of the extent of vascular contact of the trigeminal nerve is still considered the gold standard for the determination of whether nerve decompressio...

journal_title：Neurosurgery

authors： Jani RH,Hughes MA,Gold MS,Branstetter BF,Ligus ZE,Sekula RF Jr

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The presence of intracerebral hematoma from aneurysm rupture is an indication for craniotomy for clot evacuation and aneurysm clipping. Some centers have begun securing aneurysms with coil embolization followed by clot evacuation in the operating room. This approach requires transporting a patient from the a...

journal_title：Neurosurgery

authors： Turner RD,Vargas J,Turk AS,Chaudry MI,Spiotta AM

更新日期：2015-03-01 00:00:00

abstract：:As an adjuvant to surgery, radiation therapy has consistently proven to be the most successful form of treatment for primary and secondary malignant brain tumors and possibly for inoperable benign tumors. Because the risk of radiation necrosis of normal brain limits the amount of radiation that can be given by externa...

journal_title：Neurosurgery

authors： Bernstein M,Gutin PH

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVE:The supraorbital approach is well accepted for lesions in the anterior fossa, the sellar region, and the anterior circle of Willis. However, the usefulness of this approach has not yet been elucidated for lesions in the interpeduncular fossa. The technique of an endoscope-assisted, ipsi- and contralateral sup...

journal_title：Neurosurgery

authors： Menovsky T,Grotenhuis JA,de Vries J,Bartels RH

更新日期：1999-01-01 00:00:00

abstract：:The authors describe a new suction device with prehensile properties that has proved itself particularly useful in the removal of certain types of tumor, especially extramedullary. ...

journal_title：Neurosurgery

authors： Cantore G,Ciappetta P

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVE:Most of the endoscopes used for endonasal transsphenoidal surgery use 4-mm diameter lenses. The applicability of a newly developed neuroendoscope with a lens diameter of only 2 mm was tested in endonasal transsphenoidal pituitary surgery. METHODS:The newly developed rigid-rod neuroendoscope with a 2-mm lens ...

journal_title：Neurosurgery

authors： Di Rocco F,Oi S,Samii A,Paternó V,Feigl GC,Lüdemann W,Samii M

更新日期：2007-04-01 00:00:00

abstract：:Animal bite is a common cause of craniofacial injuries in children. Whereas scalp lacerations from animal bites are often extensive and severe, only four instances of compound depressed skull fractures from animal bites have been reported. A case of a dog bite to the head of an infant is presented to point out the pot...

journal_title：Neurosurgery

authors： Wilberger JE Jr,Pang D

更新日期：1981-10-01 00:00:00

abstract：OBJECTIVE:Sodium butyrate (SB), a differentiation-inducing agent, has been demonstrated to inhibit cellular proliferation in a number of human cell lines. Its precise mechanisms remain to be clarified, however. We investigated molecular mechanisms of SB-induced growth suppression as well as the effects of SB on the inv...

journal_title：Neurosurgery

authors： Ito N,Sawa H,Nagane M,Noguchi A,Hara M,Saito I

更新日期：2001-08-01 00:00:00

abstract：:We report the metastasis of a rectal carcinoid to the dura mater of the posterior fossa. The clinical presentation was unusual because of a 10-year latent period between resection of the primary rectal tumor and symptoms and signs of the posterior fossa metastasis; the radiological findings were atypical of a metastas...

journal_title：Neurosurgery

authors： Bouldin TW,Killebrew K,Boone SC,Gay RM

更新日期：1979-10-01 00:00:00