Cupressus lusitanica (Cupressaceae) leaf extract induces apoptosis in cancer cells.


:A crude ethanolic extract of Cupressus lusitanica Mill. leaves demonstrate cytotoxicity in a panel of cancer cell lines. Cell death was due to apoptosis, as assessed by morphologic features (chromatin condensation and apoptotic bodies formation) and specific DNA fragmentation detected by in situ end-labeling of DNA breaks (TUNEL). The apoptotic cell death was induced timely in a dose-dependent manner. Despite the absence of changes in the expression levels of antiapoptotic protein Bcl-2, proapoptotic Bax protein variants omega and delta were increased. These results warrant further research of possible antitumor compounds in this plant.


J Ethnopharmacol


Lopéz L,Villavicencio MA,Albores A,Martínez M,de la Garza J,Meléndez-Zajgla J,Maldonado V





Has Abstract


2002-05-01 00:00:00














  • Free radical scavenging activity of the alcoholic extract of Trewia polycarpa roots in arthritic rats.

    abstract::The alcoholic extract of Trewia polycarpa roots (TPE), which exhibited significant anti-inflammatory activity, was evaluated for the possible mode of action by studying its antioxidant potential in adjuvant-induced arthritic rats. The biological defence system constituting the superoxide dismutase, glutathione peroxid...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Chamundeeswari D,Vasantha J,Gopalakrishnan S,Sukumar E

    更新日期:2003-09-01 00:00:00

  • Traditional knowledge on poisonous plants of Udhampur district of Jammu and Kashmir, India.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Poisonous plants comprise the third largest category of poisons known around the world. Other than affecting the humans directly, they are the major cause of economic losses in the livestock industry since the advent of civilisation. Aim of the present study was to collect and systematica...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Bhatia H,Manhas RK,Kumar K,Magotra R

    更新日期:2014-02-27 00:00:00

  • Bioassay-guided isolation of active principles from Nigerian medicinal plants identifies new trypanocides with low toxicity and no cross-resistance to diamidines and arsenicals.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Leaves from the plant species studied herein are traditionally used in northern Nigeria against various protozoan infections. However, none of these herbal preparations have been standardized, nor have their toxicity to mammalian cells been investigated. In search of improved and non-toxi...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Ebiloma GU,Igoli JO,Katsoulis E,Donachie AM,Eze A,Gray AI,de Koning HP

    更新日期:2017-04-18 00:00:00

  • Chemical characterization and evaluation of gastric antiulcer properties of the hydroethanolic extract of the stem bark of Virola elongata (Benth.) Warb.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Virola elongata is a tree species belonging to the Myristicaceae family, distributed in the North and Midwest regions of Brazil, in the phytogeographic domain of the Amazon. The aqueous infusion or the hydroethanolic macerate of the stem bark of V. elongata are used in Brazilian and Ecuad...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Almeida GVB,Arunachalam K,Balogun SO,Pavan E,Ascêncio SD,Soares IM,Zanatta AC,Vilegas W,Macho A,Oliveira Martins DT

    更新日期:2019-03-01 00:00:00

  • Screening of some Indian medicinal plants for their antimicrobial properties.

    abstract::A total of 82 Indian medicinal plants traditionally used in medicines were subjected to preliminary antibacterial screening against several pathogenic and opportunistic microorganisms. Aqueous, hexane and alcoholic extracts of each plant were tested for their antibacterial activity using agar well diffusion method at ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Ahmad I,Mehmood Z,Mohammad F

    更新日期:1998-09-01 00:00:00

  • Anti-venom potential of butanolic extract of Eclipta prostrata against Malayan pit viper venom.

    abstract::The butanolic and purified butanolic extracts (PBEs) of Eclipta prostrata were evaluated for their anti-venom potential. Inhibition of lethal, hemorrhagic, proteolytic, and phospholipase A2 activities of Calloselasma rhodostoma (Malayan pit viper (MPV)) venom by these extracts were determined. Demethylwedelolactone wa...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Pithayanukul P,Laovachirasuwan S,Bavovada R,Pakmanee N,Suttisri R

    更新日期:2004-02-01 00:00:00

  • Antiurolithiatic activity of Boldoa purpurascens aqueous extract: An in vitro and in vivo study.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Boldoa purpurascens Cav. (Nyctaginaceae) is a plant species used in traditional medicine in Cuba as antiurolithiatic. AIM OF THE STUDY:The aim of the present investigation was to evaluate the in vitro and in vivo antiurolothiatic activity of an aqueous extract from the leaves of Boldoa p...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Mosquera DMG,Ortega YH,Quero PC,Martínez RS,Pieters L

    更新日期:2020-05-10 00:00:00

  • Plumeria rubra L.- A review on its ethnopharmacological, morphological, phytochemical, pharmacological and toxicological studies.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Plumeria rubra L. (Apocynaceae) is a deciduous, commonly ornamental, tropical plant grown in home premises, parks, gardens, graveyards, because of its beautiful and attractive flowers of various colours and size. The different parts of the plant are used traditionally to treat various dis...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审


    authors: Bihani T

    更新日期:2021-01-10 00:00:00

  • Central nervous system studies on an ethanol extract of Acorus calamus rhizomes.

    abstract::An ethanol extract of Acorus calamus rhizomes was screened for CNS effects using a battery of 20 tests in rats and mice. The extract exhibited a large number of actions similar to alpha-asarone (an active principle of A. calamus) but differed from the latter in several other respects including the responses to electro...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Vohora SB,Shah SA,Dandiya PC

    更新日期:1990-02-01 00:00:00

  • Anti-inflammatory activity and phenolic profile of propolis from two locations in Región Metropolitana de Santiago, Chile.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Propolis has long been used as a popular folk medicine due to its wide spectrum of alleged biological and pharmaceutical properties. In Chile, propolis is widely used by folklore medicine as an anti-inflammatory agent; however, this property has not been demonstrated by scientific methods...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Valenzuela-Barra G,Castro C,Figueroa C,Barriga A,Silva X,de Las Heras B,Hortelano S,Delporte C

    更新日期:2015-06-20 00:00:00

  • Role of cinnabar and realgar of WSHFD in protecting against LPS-induced neurotoxicity.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Wan-Sheng-Hua-Feng-Dan (WSHFD) is a traditional Chinese medicine used for the treatment of neurological disorders. Cinnabar (HgS) and realgar (As(4)S(4)) are included in WSHFD. Are they remedies or poisons? AIM OF STUDY:To investigate the role of cinnabar and realgar in the protective ef...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Zhang F,Lu Y,Wu Q,Yan J,Shi J,Liu J

    更新日期:2012-02-15 00:00:00

  • Chemopreventive activity of Ocimum sanctum seed oil.

    abstract::The seed oil of Ocimum sanctum was evaluated for chemopreventive activity against subcutaneously injected 20-methylcholanthrene induced-fibrosarcoma tumors in the thigh region of Swiss albino mice. Supplementation of maximal tolerated dose (100 microl/kg body weight) of the oil significantly reduced 20-methylcholanthr...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Prakash J,Gupta SK

    更新日期:2000-09-01 00:00:00

  • Regulatory effects of Codonopsis lanceolata on gene expression of GM-CSF in macrophage-like cells.

    abstract:AIM OF THE STUDY:We aimed to demonstrate ethnopharmacological role of Codonopsis lanceolata L., known to be used as a folk qi tonic herb to aid those who are weakened by blood loss or other injury in Korea, by examining the expressional level of hematopoietic cytokines. RESULTS:BuOH fraction strongly up-regulated mRNA...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Byeon SE,Lee YG,Cho JY

    更新日期:2009-05-04 00:00:00

  • Anti-inflammatory and antinociceptive activity of taxoids and lignans from the heartwood of Taxus baccata L.

    abstract::Four taxoids (taxusin, baccatin VI, baccatin III and 1beta-hydroxybaccatin I) and five lignans (lariciresinol, taxiresinol, 3'-demethylisolariciresinol-9'-hydroxyisopropylether, isolariciresinol and 3-demethylisolariciresinol) were isolated from the heartwood of Taxus baccata L. (Taxaceae) growing in Turkey through ch...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Küpeli E,Erdemoğlu N,Yeşilada E,Sener B

    更新日期:2003-12-01 00:00:00

  • Ethnomedicinal uses of Momordicacharantia (Cucurbitaceae) in Togo and relation to its phytochemistry and biological activity.

    abstract::Investigation of the traditional uses of Momordica charantia (Cucurbitaceae) in Togo (West Africa) showed that it is one of the most important local medicinal plants both for ritual and ethnomedical practices. There was a high degree of consensus (>50%) for use in the treatment of gastrointestinal and viral disease am...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Beloin N,Gbeassor M,Akpagana K,Hudson J,de Soussa K,Koumaglo K,Arnason JT

    更新日期:2005-01-04 00:00:00

  • The taste of heat: How humoral qualities act as a cultural filter for chemosensory properties guiding herbal medicine.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Organoleptic properties, and more specifically chemosensory cues, have been shown to guide therapeutic applications of medicinal plants. Humoral qualities, on the other hand, are widely believed to be an abstract concept, mainly applied post hoc to validate therapy. However, the nexus bet...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Geck MS,Cabras S,Casu L,Reyes García AJ,Leonti M

    更新日期:2017-02-23 00:00:00

  • The scorpion in Spanish folk medicine: a review of traditional remedies for stings and its use as a therapeutic resource.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:While scorpionism is not a serious public health problem in Spain, traditional Spanish knowledge has retained a large number of plant-based and animal-based remedies for scorpion stings. Additionally, this arthropod plays an important role in the treatment of its own sting and has become ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审


    authors: González JA,Vallejo JR

    更新日期:2013-03-07 00:00:00

  • Chemical analysis of incense smokes used in Shaxi, Southwest China: a novel methodological approach in ethnobotany.

    abstract:AIM OF THE STUDY:Characterization and comparative analysis of the main VOCs (volatile organic compounds) present in the smoke of 11 experimentally combusted plant species used as incense in Shaxi, Southwest China. Substances which may be responsible for the pleasant smell of the smokes as well as substances with a pote...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Staub PO,Schiestl FP,Leonti M,Weckerle CS

    更新日期:2011-10-31 00:00:00

  • Guaraná (Paullinia cupana var. sorbilis): ecological and social perspectives on an economic plant of the central Amazon basin.

    abstract::Guaraná is considered an ideal crop for supplementing the incomes of small peasant farmers in the Amazon basin. A fast-growing perennial, guaraná can be planted in the midst of manioc crops, allowing the formation of extensive orchards in the place of regenerating scrub once the manioc has been harvested. Traditional ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Henman AR

    更新日期:1982-11-01 00:00:00

  • Free radical scavenging and hepatoprotective activity of jigrine against galactosamine induced hepatopathy in rats.

    abstract::Jigrine a polypharmaceutical herbal hepatoprotective formulation containing aqueous extracts of 14 medicinal plants is used in Indian system of medicine (Unani). Jigrine was evaluated for its hepatoprotective activity against galactosamine induced hepatopathy in rats. Galactosamine induced hepatotoxicity resembles hum...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Najmi AK,Pillai KK,Pal SN,Aqil M

    更新日期:2005-03-21 00:00:00

  • In vitro anti-glycation activity of the marine plant Posidonia oceanica (L.) Delile.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The marine plant Posidonia oceanica (L.) Delile is traditionally used by villagers of the west coast of Anatolia as a remedy for diabetes and hypertension. AIM OF THE STUDY:The aim of this study was to explore the role of the P. oceanica hydroalcoholic leaves extract (POE) against human ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Vasarri M,Barletta E,Ramazzotti M,Degl'Innocenti D

    更新日期:2020-09-15 00:00:00

  • The comparative phytochemistry of the genus Erythroxylon.

    abstract::Recent research suggests that, in addition to the well-documented occurrence of significant quantities of cocaine and related alkaloids in a limited number of species, the genus Erythroxylon will prove to be a rich source of tropane alkaloids. These bases are esters of a range of acids with tropine, 3 alpha, 6 beta-di...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Evans WC

    更新日期:1981-03-01 00:00:00

  • Omic techniques in systems biology approaches to traditional Chinese medicine research: present and future.

    abstract::Omic techniques have become key tools in the development of systems biology. As the holistic approaches underlying the practice of traditional Chinese medicine (TCM) and new tendencies in Western medicine towards personalised medicine require in-depth knowledge of mechanisms of action and active compounds, the use of ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审


    authors: Buriani A,Garcia-Bermejo ML,Bosisio E,Xu Q,Li H,Dong X,Simmonds MS,Carrara M,Tejedor N,Lucio-Cazana J,Hylands PJ

    更新日期:2012-04-10 00:00:00

  • Antioxidant, antimicrobial and antiverotoxic potentials of extracts of Curtisia dentata.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:There is an increase in antimicrobial resistance and complexities arising from verotoxic related bacterial infections as well as rise in demand for application of natural antioxidants to combat oxidative damage by free radicals in many oxidative stress-mediated disease conditions such as ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Doughari JH,Ndakidemi PA,Human IS,Benade S

    更新日期:2012-06-14 00:00:00

  • Comparison of the anti-ulcer activity between the crude and bran-processed Atractylodes lancea in the rat model of gastric ulcer induced by acetic acid.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The rhizome of Atractylodes lancea (AL, Compositae, Chinese name: Cangzhu; Japanese name: Sou-ju-tsu) has been used traditionally for the treatment of various diseases such as digestive disorders, rheumatic diseases, and influenza in China, Korea and Japan. The crude AL and AL bran-proces...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Yu Y,Jia TZ,Cai Q,Jiang N,Ma MY,Min DY,Yuan Y

    更新日期:2015-02-03 00:00:00

  • Anti-melanoma activity of Cynanchi atrati Radix is mediated by regulation of NF-kappa B activity and pro-apoptotic proteins.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Cynanchi atrati Radix has been traditionally prescribed for patients with inflammatory fever or chronic tumoral disorders. Melanoma is one of the most devastating cancer types, in which overexpression of nuclear factor kappa B (NF-κB) enables the cancer to survive without apoptosis. To id...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Son SW,Kim HG,Han JM,Lee JS,Choi MK,Lee JS,Son CG

    更新日期:2014-04-11 00:00:00

  • Evaluation of potential herb-drug interactions between oseltamivir and commonly used anti-influenza Chinese medicinal herbs.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:According to Traditional Chinese Medicine theory, influenza is categorized as a warm disease or Wen Bing. The Wen Bing formulas, such as Yin-Qiao-San and Sang-Ju-Yin, are still first-line herbal therapies in combating variant influenza virus. To continue our study on the pharmacokinetic a...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Zhang Y,Lyu C,Fong SYK,Wang Q,Li C,Ho NJ,Chan KS,Yan X,Zuo Z

    更新日期:2019-10-28 00:00:00

  • Inhibitory effects of Saussurea involucrata (Kar. et Kir.) Sch. -Bip. on adjuvant arthritis in rats.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Saussurea involucrate (Kar. et Kir.) Sch. -Bip is an endangered species of the Compositae family, and this species has long been used for the treatment of rheumatoid arthritis, dysmenorrhea, stomachache, and altitude sickness in Uighur folk and Chinese medicine. AIM OF THE STUDY:This stu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Han X,Su D,Xian X,Zhou M,Li X,Huang J,Wang J,Gao H

    更新日期:2016-12-24 00:00:00

  • Antithrombocytopenic activity of carpaine and alkaloidal extract of Carica papaya Linn. leaves in busulfan induced thrombocytopenic Wistar rats.

    abstract:ETHNOPHARMACOLOGICAL RELAVANCE:The decoction of Carica papaya Linn. leaves is used in folklore medicine in certain parts of Malaysia and Indonesia for the treatment of different types of thrombocytopenia associated with diseases and drugs. There are several scientific studies carried out on humans and animal models to ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Zunjar V,Dash RP,Jivrajani M,Trivedi B,Nivsarkar M

    更新日期:2016-04-02 00:00:00

  • Pharmacological effects of Agapanthus africanus on the isolated rat uterus.

    abstract::The Agapanthus africanus plant is used by South African traditional healers as a phytomedicine in herbal remedies to treat pregnancy-related ailments and to augment labour. It has already been shown that an aqueous extract of A. africanus causes smooth muscle contractions in the isolated uterus and ileum preparations....

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章


    authors: Veale DJ,Havlik I,Oliver DW,Dekker TG

    更新日期:1999-09-01 00:00:00