Starting from fins: parallelism in the evolution of limbs and genitalia: the fin-to-genitalia transition.


:Organizers of the symposium Starting from Fins: Parallelism in the Evolution of Limbs and Genitalia intended it 1) to begin debates and discussions about parallelism, serial homology and transitions in development, as well as evolution of gene function and theories of origins and 2) to examine closely the potential significance of serial homology in understanding the evolution of morphology. This issue of Evolution and Development focuses on unpaired fin to genitalia transitions; the July-August issue will focus on paired fins to limbs, revisit the issues raised in the symposium, and point to future directions. Minelli's opening presentation introduced the central theme of the symposium by suggesting that body appendages such as arthropod and vertebrate limbs, chordate tails and external genitalia are evolutionarily divergent duplicates (paramorphs) of the main body axis. Suzuki's and Podlasek's presentations focused on the development of mammalian genitalia. Suzuki presented Suzuki et al investigations of the role of fibroblast growth factor (Fgf) and Sonic hedgehog (Shh) as signaling molecules during murine external genitalia formation, and Podlasek presented Podlasek et al investigations to elucidate a rudimentary pathway of essential developmental genes and transcriptional regulators such as Hox genes, Sonic hedgehog (Shh), and Bone morphogenetic proteins 2 and 4 (BMP-2; BMP-4), found in the limb. Discussions and questions emerging from the symposium point to the need to recognize that claims of phylogenetic cause must be based on something more than similarities; research must focus on the extent to which comparisons can be taken as well as on the evolutionary significance of similarities.


Evol Dev


Evolution & development


Rosa-Molinar E,Burke AC





Has Abstract


2002-03-01 00:00:00












  • Russian comparative embryology takes form: a conceptual metamorphosis toward "evo-devo".

    abstract::This essay recapitulates major paths followed by the Russian tradition of what we refer to today as evolutionary developmental biology ("evo-devo"). The article addresses several questions regarding the conceptual history of evolutionary embryological thought in its particularly Russian perspective: (1) the assertion ...

    journal_title:Evolution & development

    pub_type: 历史文章,杂志文章


    authors: Mikhailov AT

    更新日期:2012-01-01 00:00:00

  • Variations in anuran embryogenesis: yolk-rich embryos of Hyperolius puncticulatus (Hyperoliidae).

    abstract::Anuran development is usually described using model species, most notably Xenopus laevis and Rana pipiens. We describe the development of the East African Reed Frog, Hyperolius puncticulatus, a species displaying development that is highly divergent from the "classic" anuran developmental pattern. Although having smal...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Chipman AD,Haas A,Khaner O

    更新日期:1999-07-01 00:00:00

  • Coelomogenesis during the abbreviated development of the echinoid Heliocidaris erythrogramma and the developmental origin of the echinoderm pentameral body plan.

    abstract::The development of the coeloms is described in an echinoid with an abbreviated larval development and shows the early morphogenesis of the coeloms of the adult stage. The development is described from images obtained by laser scanning confocal microscopy. The development in Heliocidaris erythrogramma is asymmetric wit...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Morris VB

    更新日期:2011-07-01 00:00:00

  • Gene networks and developmental context: the importance of understanding complex gene expression patterns in evolution.

    abstract::Animal development is the product of distinct components and interactions-genes, regulatory networks, and cells-and it exhibits emergent properties that cannot be inferred from the components in isolation. Often the focus is on the genotype-to-phenotype map, overlooking the process of development that turns one into t...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Signor SA,Arbeitman MN,Nuzhdin SV

    更新日期:2016-05-01 00:00:00

  • Turning Hox "signatures" into synapomorphies.

    abstract::It has recently been shown that the three metazoan superphyla that are recognized on the basis of 18S rDNA phylogenies--ecdysozoans, lophotrochozoans, and deuterostomes--each have characteristic Hox genes. This observation has been taken further, and these "signature" Hox genes have been looked for in taxa of uncertai...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Telford MJ

    更新日期:2000-11-01 00:00:00

  • When two equals three: developmental osteology and homology of the caudal skeleton in carangid fishes (Perciformes: Carangidae).

    abstract::Ontogeny often provides the most compelling evidence for primary homology in evolutionary developmental studies and is critical to interpreting complex structures in a phylogenetic context. As an example of this, we document the ontogenetic development of the caudal skeleton of Caranx crysos by examining a series of c...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Hilton EJ,Johnson GD

    更新日期:2007-03-01 00:00:00

  • Paxbeta: a novel family of lophotrochozoan Pax genes.

    abstract::Paxbeta is a novel gene family restricted to the bilaterian superphylum Lophotrochozoa. The Paxbeta paired domain is highly diverged from other bilaterian Pax genes, and we were unable to identify an unambiguous sister-group by phylogenetic sequence analysis. However, conservation of a paired domain intron suggests th...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Schmerer M,Savage RM,Shankland M

    更新日期:2009-11-01 00:00:00

  • When molecules and morphology clash: reconciling conflicting phylogenies of the Metazoa by considering secondary character loss.

    abstract::Molecular and morphological data sets have yielded conflicting phylogenies for the Metazoa. So far, no general explanation for the existence of this conflict has been suggested. However, I believe that a neglected aspect of metazoan cladistics has introduced a systematic and substantial bias into morphological phyloge...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Jenner RA

    更新日期:2004-09-01 00:00:00

  • Role of the male BmDSX protein in the sexual differentiation of Bombyx mori.

    abstract::The sex determination pathway is different between Drosophila melanogaster and Bombyx mori in the initial signal. Here we show evidence that the sex determination pathway in B. mori is similar to that of D. melanogaster at the level of the terminal regulator, doublesex (dsx), which is essential for the proper differen...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Suzuki MG,Funaguma S,Kanda T,Tamura T,Shimada T

    更新日期:2005-01-01 00:00:00

  • Rapid shape divergences between natural and introduced populations of a horned beetle partly mirror divergences between species.

    abstract::Onthophagus taurus is a polyphenic beetle in which males express alternative major (horned) and minor (hornless) morphologies largely dependent on larval nutrition. O. taurus was originally limited to a Turanic-European-Mediterranean distribution, but became introduced to several exotic regions in the late 1960s. Usin...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Pizzo A,Roggero A,Palestrini C,Moczek AP,Rolando A

    更新日期:2008-03-01 00:00:00

  • Comparative studies on the structure and development of the venom-delivery system of centipedes, and a hypothesis on the origin of this evolutionary novelty.

    abstract::The venom-injecting forcipules of centipedes represent an evolutionary novelty that appeared in the centipede stem lineage more than 400 Ma. No other lineage of arthropods (or indeed of animals) has evolved claws for injecting venom from a pair of walking legs. However, little is known of the development, ultrastructu...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Dugon MM,Arthur W

    更新日期:2012-01-01 00:00:00

  • Larval and adult brains.

    abstract::Apical organs are a well-known structure in almost all ciliated eumetazoan larvae, although their function is poorly known. A review of the literature indicates that this small ganglion is the "brain" of the early larva, and it seems probable that it represents the brain of the ancestral, holopelagic ancestor of all e...

    journal_title:Evolution & development

    pub_type: 杂志文章,评审


    authors: Nielsen C

    更新日期:2005-09-01 00:00:00

  • Ontogenic potentialities of the worker caste in two sympatric subterranean termites in France.

    abstract::In termites, the capacity of workers to differentiate into neotenic reproductives is an important characteristic that deserves particular attention. To gain insight into the differentiation pathway, the potentialities of workers and the endocrinal changes during the formation of neotenics were compared in two sympatri...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Leniaud L,Darrouzet E,Dedeine F,Ahn K,Huang Z,Bagnères AG

    更新日期:2011-03-01 00:00:00

  • Degeneration patterns of the worker spermatheca during morphogenesis in ants (Hymenoptera: Formicidae).

    abstract::Reproductive division of labor is one of the crucial features in social insects, however, the developmental mechanisms leading to modifications in the reproductive apparatus of workers are still not very clear. Ants show a remarkable diversity in the morphological specialization of the worker's reproductive apparatus,...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Gotoh A,Billen J,Hashim R,Ito F

    更新日期:2016-03-01 00:00:00

  • Maxillopedia is the Tribolium ortholog of proboscipedia.

    abstract::Null mutations in the Drosophila melanogaster homeotic gene proboscipedia (pb) cause transformation of the adult labial palps to legs. The similar phenotype produced by mutations in the Tribolium castaneum homeotic complex (HOMC) gene maxillopedia (mxp) has led to suggestions that the two genes may be orthologous. We ...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Shippy TD,Brown SJ,Denell RE

    更新日期:2000-05-01 00:00:00

  • Does resource availability help determine the evolutionary route to multicellularity?

    abstract::Genetic heterogeneity and homogeneity are associated with distinct sets of adaptive advantages and bottlenecks, both in developmental biology and population genetics. Whereas populations of individuals are usually genetically heterogeneous, most multicellular metazoans are genetically homogeneous. Observing that resou...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Hamant O,Bhat R,Nanjundiah V,Newman SA

    更新日期:2019-05-01 00:00:00

  • The making of the defensive caste: Physiology, development, and evolution of the soldier differentiation in termites.

    abstract::Termites (Blattodea, Termitoidea, or Isoptera) constitute one of the major lineages of eusocial insects. In termite societies, multiple types of functional individuals, that is, castes, perform divisions of labors to coordinate social behaviors. Among other castes, the soldier caste is distinctive since it is sterile ...

    journal_title:Evolution & development

    pub_type: 杂志文章,评审


    authors: Miura T,Maekawa K

    更新日期:2020-11-01 00:00:00

  • Ontogenetic allometry in the thoracolumbar spine of mammal species with differing gait use.

    abstract::Vertebrae are serially homologous structures with tight integration through their evolution and development. However, in mammals, the thoracic and lumbar regions are morphologically and functionally differentiated. We test the hypothesis that locomotor specialization is associated with altered post-natal growth patter...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Jones KE,German RZ

    更新日期:2014-03-01 00:00:00

  • How the cladoceran heterogonic life cycle evolved--insights from gamogenetic reproduction and direct development in Cyclestherida.

    abstract::Here we document the early gamogenetic development of Cyclestherida, including a characterization of the nervous system. Resting eggs in Cyclestheria are protected by an ephippium, built by the major part of the carapace. The first stages of development are enclosed in an outer chorion and an inner vitelline membrane....

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Fritsch M,Richter S

    更新日期:2015-11-01 00:00:00

  • Modularity in the skull and cranial vasculature of laboratory mice: implications for the evolution of complex phenotypes.

    abstract::The generation of coordinated morphological change over time results from the interconnectedness of evolution and development. The modular architecture of development results in varying degrees of integration and independence among parts of the phenotype, and facilitates the production of phenotypic variation in compl...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Jamniczky HA,Hallgrímsson B

    更新日期:2011-01-01 00:00:00

  • Widespread RNA segregation in a spiralian embryo.

    abstract::Asymmetric cell divisions are a crucial mode of cell fate specification in multicellular organisms, but their relative contribution to early embryonic patterning varies among taxa. In the embryo of the mollusc Ilyanassa, most of the early cell divisions are overtly asymmetric. During Ilyanassa early cleavage, mRNAs fo...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Kingsley EP,Chan XY,Duan Y,Lambert JD

    更新日期:2007-11-01 00:00:00

  • Early evolution of a homeobox gene: the parahox gene Gsx in the Cnidaria and the Bilateria.

    abstract::Homeobox transcription factors are commonly involved in developmental regulation in diverse eukaryotes, including plants, animals, and fungi. The origin of novel homeobox genes is thought to have contributed to many evolutionary innovations in animals. We perform a molecular phylogenetic analysis of cnox2, the best st...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Finnerty JR,Paulson D,Burton P,Pang K,Martindale MQ

    更新日期:2003-07-01 00:00:00

  • Neurogenesis in the crustacean ventral nerve cord: homology of neuronal stem cells in Malacostraca and Branchiopoda?

    abstract::In Insecta and malacostracan Crustacea, neurons in the ventral ganglia are generated by the unequal division of neuronal stem cells, the neuroblasts (Nbs), which are arranged in a stereotyped, grid-like pattern. In malacostracans, however, Nbs originate from ectoteloblasts by an invariant lineage, whereas Nbs in insec...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Harzsch S

    更新日期:2001-05-01 00:00:00

  • Developmental integration in a complex morphological structure: how distinct are the modules in the mouse mandible?

    abstract::The mouse mandible has long served as a model system for studying the development and evolution of complex morphological structures. We used the methods of geometric morphometrics to reassess the hypothesis that the mandible consists of two separate modules: an anterior part bearing the teeth and a posterior part with...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Klingenberg CP,Mebus K,Auffray JC

    更新日期:2003-09-01 00:00:00

  • Spontaneous homeotic mutants and genetic control of floral organ identity in a ranunculid.

    abstract::The regulation of floral organ identity was investigated using a forward genetic approach in five floral homeotic mutants of Thalictrum, a noncore eudicot. We hypothesized that these mutants carry defects in the floral patterning genes. Mutant characterization comprised comparative floral morphology and organ identity...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Martínez-Gómez J,Galimba KD,Coté EY,Sullivan AM,Di Stilio VS

    更新日期:2020-11-12 00:00:00

  • Evolution of male sexual characters in the oriental Drosophila melanogaster species group.

    abstract::Understanding the genetic and molecular mechanisms of morphological evolution is one of the greatest challenges in evolutionary biology. Sexually dimorphic traits, which often evolve at a high rate due to their involvement in mate choice and sexual selection, present unique opportunities for investigating changes in d...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Kopp A,True JR

    更新日期:2002-07-01 00:00:00

  • Actors of the tyrosine kinase receptor downstream signaling pathways in amphioxus.

    abstract::One of the major goals of evo-developmentalists is to understand how the genetic mechanisms controlling embryonic development have evolved to create the current diversity of bodyplans that we encounter in the animal kingdom. Tyrosine kinase receptors (RTKs) are transmembrane receptors present in all metazoans known to...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Bertrand S,Campo-Paysaa F,Camasses A,García-Fernàndez J,Escrivà H

    更新日期:2009-01-01 00:00:00

  • European Christians are at the forefront in accepting evolution: results from an internet-based survey.

    abstract::Beliefs regarding the origins of the universe and life differ substantially between groups of people and are often particularly associated with religious worldviews. It is important to understand factors associated with evolution and creationism beliefs and unacceptance of scientific evidence for evolution. An interne...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Wilson DP

    更新日期:2010-11-01 00:00:00

  • Developmental expression of foxA and gata genes during gut formation in the polychaete annelid, Capitella sp. I.

    abstract::Most bilaterian animals have evolved a through gut that is regionally specialized along the anterior-posterior axis. In the polychaete annelid, Capitella sp. I, the alimentary canal is subdivided into a buccal cavity, pharynx, esophagus, midgut, and hindgut. Members of the Fox and GATA families of transcription factor...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Boyle MJ,Seaver EC

    更新日期:2008-01-01 00:00:00

  • AINTEGUMENTA homolog expression in Gnetum (gymnosperms) and implications for the evolution of ovulate axes in seed plants.

    abstract::The expression of GpANTL1, a homolog of AINTEGUMENTA (ANT) found in the gymnosperm Gnetum parvifolium, was analyzed by RT-PCR and in situ hybridization. GpANTL1 was expressed in the leaf primordia, root tips, and young ovules. In the ovulate axis, expression was detected as four distinct rings around the outer, middle...

    journal_title:Evolution & development

    pub_type: 杂志文章


    authors: Yamada T,Hirayama Y,Imaichi R,Kato M

    更新日期:2008-05-01 00:00:00