当前位置： SCI文献检索 > JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS期刊下所有文献 > An observational study on patients treated or not for acute HIV infection.

An observational study on patients treated or not for acute HIV infection.

Abstract：

BACKGROUND:A vast majority of HIV-infected subjects who experience HIV acute seroconversion actually receive treatment. Open questions are how can we identify patients who will be slow progressors or long-term non progressors, and, as a consequence, do not require treatment. METHODS:An observational retrospective study on patients who experienced acute HIV seroconversion from August 1995 to June 2001, who are still alive and followed as outpatients at the Clinic of Infectious Diseases of Modena, Italy. RESULTS:Twelve patients were studied. Five patients (45.4%) were treated during acute seroconversion, while 7 were not treated. Two of these seven subjects received antiretroviral treatment 12 and 26 weeks after acute seroconversion. All the untreated patients were in good viro-immunological condition 6 months after seroconversion, and 2 of them also after 3 and 7 years. Patients who were treated showed a significant daily increase in CD4/CD8 T cell ratio with longer time spent on therapy (0.04% increase per day longer on antiretroviral therapy, p=0.02). CONCLUSIONS:This study suggests that treatment during primary HIV infection should not be considered in all patients. Randomized clinical trials enrolling patients with an asymptomatic primary HIV infection, with a high CD4 count and low HIV plasma viremia are needed to evaluate the indications for treatment in this subgroup of patients. On the other hand, this study confirms the good viro-immunological response obtained after treating patients during primary HIV infection.

journal_name

J Biol Regul Homeost Agents

journal_title

Journal of biological regulators and homeostatic agents

authors

Mussini C,Cozzi-Lepri A,Bedini A,Borghi V,Mongiardo N,Cossarizza A,Esposito R

keywords:

subject

Has Abstract

pub_date

2002-01-01 00:00:00

pages

79-82

issue

1

eissn

0393-974X

issn

1724-6083

journal_volume

16

pub_type

杂志文章

相关文献

JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS文献大全
  • Effects of recombinant human interferon alpha on human megakaryocyte and fibroblast colony formation.

    abstract：:Effects of recombinant human interferon alpha (HuIFN-alpha) on human megakaryocyte (CFU-MK) and fibroblast (CFU-F) colony-forming cell growth were studied. Concentration-dependent inhibition of both CFU-MK and CFU-F by HuIFN-alpha was demonstrated. Statistically significant suppression of both CFU-MK and CFU-F was see...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Han ZC,Briere J,Abgrall JF,Le Gall G,Parent D,Sencebe L

    更新日期：1987-10-01 00:00:00

  • The effects of collagenase of Clostridium Histolitycum (CCH) in Dupuytren's disease: a histological study on cell mediated mechanisms that allow enzymatic fasciotomy.

    abstract：:Dupuytren Disease is a benign fibromatosis of palmar fascia of the hand, whose pathophysiology is not completely understood. The present study is intended to provide a description of the effects of Collagenase of Clostridium Hystoliticum (CCH) into an injected cord of Dupuytren. Our experimental study wanted to evalua...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type：

    doi：

    authors： Passiatore M,De Vitis R,Saracco M,Brunelli C,Castri F,Taccardo G

    更新日期：2020-07-01 00:00:00

  • A short novel about the spread of two important diseases in history: syphilis and SARS.

    abstract：:Throughout the centuries, the undefended nature of man has very often manifested in cases of epidemics, which have determined scenarios of suffering and death. Through “historical” observation lens, it is possible to understand the relationship between the spread of viruses, bacteria and parasites responsible for thes...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Rovesti M,Satolli F,Zucchi A,Gandolfi M,Fioranelli M,Roccia MG,Boccalari M,França K,Lotti J,Zerbinati N,Lotti T,Feliciani C

    更新日期：2017-04-01 00:00:00

  • Beneficial effects of protein hydrolysates in exercise and sports nutrition.

    abstract：:Protein hydrolysates (PH) are rich sources of proteins that supply the need of exercising muscles. PHs are enriched in di- and tripeptides and are better than free amino acids or intact proteins when muscle anabolic effect is considered. Digestion, absorption and muscle uptake of amino acids are faster and more effici...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章,评审

    doi：

    authors： Yuan J,Jiang B,Li K,Shen W,Tang JL

    更新日期：2017-01-01 00:00:00

  • Resveratrol in Chlamydia pneumoniae-induced foam cell formation and interleukin-17A synthesis.

    abstract：:The involvement of Chlamydia pneumoniae in the pathogenesis of atherosclerosis has been suggested by numerous seroepidemiological, in vivo and in vitro studies. In particular, it has been shown that C. pneumoniae is able to promote the accumulation of low-density lipoproteins into macrophages, thus facilitating foam c...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Di Pietro M,De Santis F,Schiavoni G,Filardo S,Sessa R

    更新日期：2013-04-01 00:00:00

  • Carbon Ion Radiotherapy for sacral chordoma: a systematic review of the literature.

    abstract：:The aim of the present study is to describe the clinical outcomes and the incidence of complications related to Carbon Ion Radiotherapy (CIRT) in the treatment of sacral chordoma. Through a systematic review of published investigations on CIRT, we collected the local control rates (LC), the overall survival rates (OS)...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Evangelisti G,Sartini F,Bandiera S,Barbanti Brodano G,Griffoni C,Girolami M,Pipola V,Gasbarrini A

    更新日期：2020-07-01 00:00:00

  • Diode laser as an adjunct to nonsurgical chronic periodontitis therapy: a review.

    abstract：:The aim of this review was to investigate the additional effects of diode laser irradiation in combination with nonsurgical periodontal therapy. An electronic search of publications was established from three electronic databases: Cochrane, PubMed and Web of Science. The search strategy used a combination of controlle...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章,评审

    doi：

    authors： DENTAL SUPPLEMENT.,Carosi P,Barlattani A Jr,Lorenzi C,Dolci A,Bianchi N,Arcuri C

    更新日期：2020-05-01 00:00:00

  • E-CADHERIN CODING GENE (CDH1) AND NONSYNDROMIC CLEFT LIP WITH OR WITHOUT CLEFT PALATE: IS THERE ANY ASSOCIATION?

    abstract：:Epithelial to Mesenchymal Transition (EMT) is an important process involved in cancer, embryogenesis and organ development. Its role in nonsyndromic cleft lip with or without cleft palate (NSCL/P) has been extensively investigated and successfully linked to the disease. In this study, we focused on a gene, CDH1, encod...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Girardi A,Scapoli L,Cura F,Palmieri A,Carinci F,Morselli PG,Spinelli G,Caramelli E,Martinelli M

    更新日期：2015-07-01 00:00:00

  • LncRNA XIST regulates cell proliferation, migration and invasion of glioblastoma via regulating miR-448 and ROCK1.

    abstract：:Long non-coding ribonucleic acids (lncRNAs) have been recognized as markers in several cancers and play important roles in glioblastoma (GBM). But the role of lncRNA X inactive-specific transcript (XIST) in GBM and its possible mechanisms are rarely studied in depth. This study was conducted to explore the detailed ro...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：10.23812/20-558-L

    authors： Li HL,Han PH,Pan DQ,Chen G,Lu XH,Li J

    更新日期：2020-11-01 00:00:00

  • Obese visceral adipose tissue grafted in lean mice can alter glucose homeostasis and energy efficiency.

    abstract：:Fat transplantation experiments have previously shown regulatory properties of lean adipose tissue on glucose homeostasis in the whole animal. In the current study, we addressed whether obese visceral white adipose tissue grafted in lean mice could alter glucose homeostasis. Obese visceral fat (VF) tissue was effectiv...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Barrera C,Gatica A,Morgan C

    更新日期：2012-07-01 00:00:00

  • Lymphatic edema of the lower limbs after orthopedic surgery: results of a randomized, open-label clinical trial with a new extended-release preparation.

    abstract：:The lymphedema is a high interstitial protein concentration edema, caused by impaired lymphatic transport capacity. It can be primary or secondary. The secondary form may be caused by a lesion of the lymphatic vessels and/or lymph nodes during diagnostic or therapeutic procedures such as surgical interventions. Often,...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章,随机对照试验

    doi：

    authors： Lessiani G,Iodice P,Nicolucci E,Gentili M

    更新日期：2015-10-01 00:00:00

  • Expression of p16 and p27 protein in cervical exfoliated cells and its relationship with high risk human papilloma virus in cervical lesions.

    abstract：: ...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 信件

    doi：

    authors： Miao H,Cao B,Ge W,Zhao W

    更新日期：2019-01-01 00:00:00

  • Osteogenic properties of human dental pulp stem cells.

    abstract：:Stem cells are a promising tool for bone tissue regeneration. Dental pulp stem cells (DPSCs) can be easily obtained even in human young adults. In this study we investigated the capability of DPSCs, to express the osteoblastic phenotype when cultured with osteogenic medium. DPSCs isolated from the dental pulp of impac...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Mori G,Centonze M,Brunetti G,Ballini A,Oranger A,Mori C,Lo Muzio L,Tetè S,Ciccolella F,Colucci S,Grano M,Grassi FR

    更新日期：2010-04-01 00:00:00

  • Neuroendocrine effects of interferon alpha 2-a in healthy human subjects.

    abstract：:The acute effects of interferon alpha-2a (3 x 10 IU im) on catecholamine and immunoreactive beta endorphin plasma levels, cortisol serum levels and lymphocyte beta 2-adrenoceptor density were evaluated in ten healthy volunteers. Interferon induced a significant increase in plasma norepinephrine; there was an increased...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Pende A,Musso NR,Vergassola C,Puppo F,Ioverno A,Criscuolo D,Indiveri F,Lotti G

    更新日期：1990-04-01 00:00:00

  • Flake size-dependent cyto and genotoxic evaluation of graphene oxide on in vitro A549, CaCo2 and vero cell lines.

    abstract：:This study was carried out by varying both graphene oxide (GO) concentration (10 μg/mL, 50 μg/mL, 100 μg/mL) and flakes sizes of 1320 nm and 130 nm. Characterization by scanning electron microscopy and Raman spectroscopy demonstrate that the area of GO flakes varies of one order of magnitude but their c...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： De Marzi L,Ottaviano L,Perrozzi F,Nardone M,Santucci S,De Lapuente J,Borras M,Treossi E,Palermo V,Poma A

    更新日期：2014-04-01 00:00:00

  • LINC00473 promotes lung adenocarcinoma progression by regulating miR-1294/ROBO1 axis.

    abstract：:Long noncoding RNA (lncRNA) LINC00473 has been reported to be involved in the regulation of several human cancers. However, the regulatory mechanism of LINC00473 is still unknown in lung adenocarcinoma. In this study, RT-qPCR was used to measure the expression of LINC00473, miR-1294 and ROBO1. The functional mechanism...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：10.23812/20-75A

    authors： Wang S,Wang X,Xu SL

    更新日期：2020-04-29 00:00:00

  • Entero-colpo-defecography vs supine entero-MRI: which one is the best tool in the differentiation of enterocele, elytrocele and edrocele?

    abstract：:Pelvic floor disorders represent a significant cause of morbidity associated with a severe reduction of quality of life. It represents a very common clinical problem that afflicts women three to seven time more often than men. The purpose of this study was to assess the diagnostic tools available to define the imaging...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Faggian A,Alabiso ME,Serra N,Pizza NL,Iasiello F,Tecame M,Somma F,Rossi C,Di Grezia G,Feragalli B,Iacomino A,Grassi R

    更新日期：2013-07-01 00:00:00

  • Flow cytometric enumeration and immunophenotyping of hematopoietic stem and progenitor cells.

    abstract：:Flow cytometric enumeration of CD34+ hematopoietic stem and progenitor cells (HPC) is widely used for evaluation of graft adequacy of peripheral blood stem cell grafts, and is also useful in planning the apheresis sessions necessary to obtain these grafts. The state-of-the-art method to enumerate CD34+ cells makes use...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章,评审

    doi：

    authors： Gratama JW,Sutherland DR,Keeney M,Papa S

    更新日期：2001-01-01 00:00:00

  • Diagnostic value of TRACP5b expression in patients with bone tumors.

    abstract：:In order to investigate the diagnostic value of serum levels of tartrate-resistant acid phosphatase 5b (TRACP5b) in patients with bone tumors, enzyme linked immunosorbent assay (ELISA) was used to com¬pare serum levels of TRACP5b and alkaline phosphatase (ALP) in bone tumor patients (experimental group, 80 cases) and ...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 信件

    doi：

    authors： Zhang Q,Cao L,Miao XD,Wu YP

    更新日期：2019-03-01 00:00:00

  • Oral-facial-digital syndrome (OFD): 31-year follow-up management and monitoring.

    abstract：:Orofaciodigital syndrome (OFD) is a group of hereditary disorders identified by malformations of the mouth (oris), face (facies), hands and feet (digitus=finger and toe). Although there are several different types reported in the literature, there is a great overlap in their clinical presentation. The full spectrum of...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Minervini G,Romano A,Petruzzi M,Maio C,Serpico R,Di Stasio D,Lucchese A

    更新日期：2018-01-01 00:00:00

  • Study of GSK3b inhibitors SB415286 and SB216763 to improve osteoblastic differentiation on microstructured titanium.

    abstract：:Rough titanium surfaces enhance cell response to activation of Wnt canonical signalling, a pathway required for osteoblast differentiation. The present study investigated the effects of GSK3β-inhibitors SB216763 and SB415286 on osteoblastic differentiation on titanium surfaces with different topography and wettability...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Lumetti S,Calciolari E,Parisi L,Toffoli A,Mazzotta S,Ferrillo S,Ierardo G,Macaluso GM,Galli C,Manfredi E

    更新日期：2017-07-01 00:00:00

  • Cyclosporin A in combination with HAART in primary HIV-1 infection.

    abstract：:HAART is the cornerstone of HIV therapy, and has significantly reduced morbidity and mortality associated with HIV disease. The institution of HAART during the primary HIV-1 infection has a more profound influence on the ultimate pattern and rate of disease progression than therapy commenced later on. However, it also...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： Rizzardi GP,Vaccarezza M,Capiluppi B,Tambussi G,Lazzarin A,Pantaleo G

    更新日期：2000-01-01 00:00:00

  • Evaluation of the periodontal healing of the second mandibular molar distal site following insertion of PRF in the third molar post extraction alveolus.

    abstract：:The aim of this study was to evaluate the periodontal healing of the distal sites of the mandibular second molars, comparing the extraction therapy of the third molar with and without PRF adjunct into the postextraction alveolus. The study sample was composed by 40 consecutive patients who underwent extraction of mand...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type：

    doi：

    authors： Passarelli PC,Romeo A,Lopez MA,De Angelis P,Desantis V,Piccirillo GB,Papa R,Papi P,Pompa G,Moffa A,Casale M,D'Addona A

    更新日期：2020-09-01 00:00:00

  • Etiological periodontal treatment with and without low-level laser therapy on IL-1β level in gingival crevicular fluid: an in vivo multicentric pilot study.

    abstract：:Cytokine proteins may have important roles during different human physiological and pathological processes. In the oral cavity, the bone loss and periodontal tissue pathology was related to inflammatory process activation. The aim of the present study was to assess the effects of etiological periodontal therapy with a...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 信件,多中心研究,随机对照试验

    doi：

    authors： Mastrangelo F,Dedola A,Cattoni F,Ferrini F,Bova F,Tatullo M,Gherlone E,Lo Muzio L

    更新日期：2018-03-01 00:00:00

  • Expression of poly(ADP-ribose) polymerase in bone regeneration.

    abstract：:Poly(ADP-ribose) polymerase (PARP) is a 116kDa enzyme catalysing the synthesis of ADP-ribose polymers from NAD+. PARP is activated in response to DNA strand breaks and plays a critical role in the maintenance of genomic integrity. However, considering its role also in transcription, proliferation as well as apoptosis ...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 信件

    doi：

    authors： Lo Muzio L,Pannone G,Santarelli A,Lo Russo L,De Lillo A,Rubini C,Bambini F,Bufo P,Dioguardi M,Procaccini M

    更新日期：2014-10-01 00:00:00

  • Mechanism of high-fat diet-induced non-alcoholic fatty liver disease..

    abstract：: ...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 信件

    doi：

    authors： Qiao XL,Dong Y,Feng XY,Wang HQ,Jiang CM

    更新日期：2019-01-01 00:00:00

  • Intra-articular hyaluronic acid injections for hip osteoarthritis.

    abstract：:Although viscosupplementation has been used in the past few years both for knee and hip osteoarthritis (OA), the number of intra-articular injections and the interval between doses still remains an undetermined subject. The aim of this open retrospective study was to evaluate the clinical and functional outcome in pat...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 信件

    doi：

    authors： Letizia Mauro G,Scaturro D,Sanfilippo A,Benedetti MG

    更新日期：2018-09-01 00:00:00

  • Low-dose ionizing radiation exposure: understanding the risk for cellular transformation.

    abstract：:Radiation is energy transfer. When radiation has sufficient energy to remove an orbital electron from its atom, an ionized atom is formed, and radiation with the capacity to do this is called ionizing radiation. The primary effect of radiation is the induction of free radicals and Reactive Oxygen Species (ROS). All th...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 杂志文章

    doi：

    authors： De Saint-Georges L

    更新日期：2004-04-01 00:00:00

  • Magnesium alginate in children with uncontrolled asthma.

    abstract：:Gastroesophageal reflux disease (GERD) may be frequently associated with asthma in children and may affect asthma control. Proton pump inhibitors (PPI) are commonly prescribed in asthmatic children, despite uncertain efficacy on respiratory symptoms and risk of relevant adverse effects. ...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 信件

    doi：

    authors： Miraglia Del Giudice M,Indolfi C,Ciprandi G,Decimo F,Campana G,Umano GR,Giannetti E,Maglione M

    更新日期：2019-03-01 00:00:00

  • Alkaline phosphatase level in gingival crevicular fluid during treatment with Quad-Helix.

    abstract：:The aim of this work is to assess the level of the human alkaline phosphatase enzyme (ALP) during palatal expansion with Quad-Helix (QH) appliance. A total of twenty-two orthodontic patients characterized by contraction of the upper jaw, that needed application of a QH in order to treat their condition, were included ...

    journal_title：Journal of biological regulators and homeostatic agents

    pub_type： 信件

    doi：

    authors： Delli Mauri A,Petrini M,Vitale D,Tecco S,Festa F,Barbato E,Spoto G

    更新日期：2015-10-01 00:00:00