Influence of dietary fat on beta-carotene absorption and bioconversion into vitamin A.


:Dietary fat facilitates the utilization of carotenoids and, based on serum beta-carotene or retinol responses following ingestion of meals containing carotene and fat sources, it has been reported that the amount of fat required in a meal may be minimal (approximately 3-5 g). However, the dietary fat requirement for optimal carotene utilization in humans cannot be fully ascertained without longer-term dose-response studies that measure the changes in vitamin A body stores in response to varying levels of dietary fat. In humans, vitamin A body stores can be determined by use of stable isotope-dilution methods. Animal studies have shown that although the level of dietary fat has no effect on serum vitamin A concentrations of animals fed beta-carotene, higher liver vitamin A concentrations were found in those that ingested higher fat levels. Other factors that might influence the relationship of fat intake and beta-carotene utilization include the type of fat ingested, physicochemical properties of the carotenoid source, amount of carotene ingested, whether fat and beta-carotene sources are provided in the same meal, the presence of helminthic infections, age, and vitamin A status.


Nutr Rev


Nutrition reviews


Ribaya-Mercado JD





Has Abstract


2002-04-01 00:00:00












  • Garlic: its anticarcinogenic and antitumorigenic properties.

    abstract::Overall, several investigations indicate that garlic and its organic allyl sulfur components inhibit the cancer process. Furthermore, these studies reveal that the benefits of garlic are not limited to a specific species, a particular tissue, or a specific carcinogen. Finally, odor is not a prerequisite for the protec...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Milner JA

    更新日期:1996-11-01 00:00:00

  • Vitamin D and multiple sclerosis: an update.

    abstract::Observational studies document a positive relationship between vitamin D from the environment (sunlight or diet), circulating vitamin D status, and improved symptoms or prevention of multiple sclerosis (MS). Experimental animal models of MS reproduce the beneficial effects of vitamin D and 1,25(OH)(2)D(3). The geograp...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Cantorna MT

    更新日期:2008-10-01 00:00:00

  • Retail food environment around schools and overweight: a systematic review.

    abstract:CONTEXT:The presence of retail food establishments around schools can be a potentiating or protective factor for overweight in students, depending on access to these places as well as types of foods available therein. The hypothesis for this study was that a greater density and proximity of retail food establishments a...

    journal_title:Nutrition reviews

    pub_type: 杂志文章


    authors: da Costa Peres CM,Gardone DS,Costa BVL,Duarte CK,Pessoa MC,Mendes LL

    更新日期:2020-10-01 00:00:00

  • Timing of umbilical cord clamping: effect on iron endowment of the newborn and later iron status.

    abstract::The optimal timing of umbilical cord clamping has been debated in the scientific literature for at least the last century, when cord clamping practices shifted from delayed towards immediate clamping. Recent research provides evidence for the beneficial effect of delayed cord clamping on infant iron status. The presen...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Chaparro CM

    更新日期:2011-11-01 00:00:00

  • Was the "anti-infective" vitamin misnamed?

    abstract::Meta-analyses on 6 of 12 studies of the effect of improvement of the vitamin A status of deficient children living in poverty and social and biological deprivation conclude that mortality reduction can be expected. The demonstrated effects on incidence, prevalence and severity of specific morbidities under these condi...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Underwood BA

    更新日期:1994-04-01 00:00:00

  • The influence of dietary fat on carcinogenesis: lessons from experimental models.

    abstract::Recent studies of the effects of dietary fat on experimental carcinogenesis have probed the influence of the dietary fat source, the time during carcinogenesis when a high-fat diet is fed, the interactions between fat and calories, and the potential mechanisms for the observed effects of fat on cancer. The essential f...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Birt DF

    更新日期:1990-01-01 00:00:00

  • Sulforaphane: translational research from laboratory bench to clinic.

    abstract::Cruciferous vegetables are widely acknowledged to provide chemopreventive benefits in humans, but they are not generally consumed at levels that effect significant change in biomarkers of health. Because consumers have embraced the notion that dietary supplements may prevent disease, this review considers whether an a...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Houghton CA,Fassett RG,Coombes JS

    更新日期:2013-11-01 00:00:00

  • 3-Methyl Histidine Excretion in Starvation.

    abstract::Urinary excretion of 3-methyl histidine was found to be reduced in starvation. Data show that the rate of muscle catabolism is reduced to a greater extent than muscle mass. Reutilization of amino acids appears not to be greatly enhanced during starvation. ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章



    更新日期:1974-07-01 00:00:00

  • Synbiotic therapy: a promising new adjunctive therapy for ulcerative colitis.

    abstract::Prebiotic and probiotic therapies are new strategies being used to treat gastrointestinal diseases. Recent evidence suggests that the administration of select prebiotics and probiotics, alone or in combination (the latter called "synbiotic" therapy) may improve the clinical outcome of patients with ulcerative colitis....

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Haskey N,Dahl WJ

    更新日期:2006-03-01 00:00:00

  • L-tryptophan use and the eosinophilia-myalgia syndrome.

    abstract::We present a case of the eosinophilia-myalgia syndrome in a patient taking large doses of L-tryptophan for sedation. He developed the now-classic findings of myalgias, skin changes, and marked eosinophilia. This syndrome was first recognized in late 1989, and epidemiologic studies have demonstrated an association of t...

    journal_title:Nutrition reviews

    pub_type: 杂志文章


    authors: Shocket ID,Golar K

    更新日期:1990-08-01 00:00:00

  • Seaweed and human health.

    abstract::Seaweeds may have an important role in modulating chronic disease. Rich in unique bioactive compounds not present in terrestrial food sources, including different proteins (lectins, phycobiliproteins, peptides, and amino acids), polyphenols, and polysaccharides, seaweeds are a novel source of compounds with potential ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Brown ES,Allsopp PJ,Magee PJ,Gill CI,Nitecki S,Strain CR,McSorley EM

    更新日期:2014-03-01 00:00:00

  • Weanling diarrhea: a case report.

    abstract::This case report describes a 14-month-old Guatemalan boy suffering from diarrhea and malnutrition. He had been healthy and experienced normal growth until weaning, which began at six months of age. Introduction of semisolid foods at this time was accompanied by bouts of diarrhea and a reduced growth rate. After admiss...

    journal_title:Nutrition reviews

    pub_type: 杂志文章


    authors: Solomons NW,Molina S,Bulux J

    更新日期:1990-05-01 00:00:00

  • Diet Preferences and Specificity of Hungers in Rats Fed Diets Deficient in Various Vitamins and Minerals.

    abstract::Some specific hungers for vitamins or minerals can be explained as learned preferences, facilitated by the novel diet preferences shown by rats deficient in specific nutrients. Specific hunger for sodium, however, is a result of an innate, unlearned behavior pattern. ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章



    更新日期:1968-01-01 00:00:00

  • Selenium in human lactation.

    abstract::The primary factor determining selenium concentration in human milk is the maternal selenium intake. A significant correlation between selenium in human milk and maternal selenium intake has been reviewed in papers from different regions of the world. Infants fed human milk have higher selenium intake than those fed c...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Sanz Alaejos M,Diaz Romero C

    更新日期:1995-06-01 00:00:00

  • Reviewing the evidence on breast milk composition and immunological outcomes.

    abstract::A large number of biologically active components have been found in human milk (HM), and in both human and animal models, studies have provided some evidence suggesting that HM composition can be altered by maternal exposures, subsequently influencing health outcomes for the breastfed child. Evidence varies from the r...

    journal_title:Nutrition reviews

    pub_type: 杂志文章


    authors: Boix-Amorós A,Collado MC,Van't Land B,Calvert A,Le Doare K,Garssen J,Hanna H,Khaleva E,Peroni DG,Geddes DT,Kozyrskyj AL,Warner JO,Munblit D

    更新日期:2019-05-21 00:00:00

  • Discovery of the hemochromatosis gene will require rethinking the regulation of iron metabolism.

    abstract::The identity of the protein responsible for hemochromatosis, the iron overload disease, has eluded scientists for years. However, a recent report identifies the gene where the hemochromatosis defect lies. It is a gene that encodes a major histocompatibility complex (MHC) class-1-like protein called HLA-H. The mechanis...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Fleet JC

    更新日期:1996-09-01 00:00:00

  • Food shortages and an epidemic of optic and peripheral neuropathy in Cuba.

    abstract::From late 1991 to mid-1993, cases of optic neuropathy of unknown etiology, which first appeared in unusual numbers in a western province of Cuba, spread and multiplied throughout the island. The dominant symptoms changed, becoming increasingly those of peripheral neuropathy. Incidence rates peaked in April 1993. An es...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Tucker K,Hedges TR

    更新日期:1993-12-01 00:00:00

  • Anti-inflammatory effect of anthocyanins via modulation of nuclear factor-κB and mitogen-activated protein kinase signaling cascades.

    abstract::Anthocyanins are a group of bioactive compounds present in plant foods. Although they have consistently shown an anti-inflammatory effect both in vitro and in vivo, their mechanisms of action are not fully understood and have only recently begun to be elucidated. The aim of this review is to highlight the anti-inflamm...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Vendrame S,Klimis-Zacas D

    更新日期:2015-06-01 00:00:00

  • 1 alpha,25(OH)2 vitamin D3-regulated expression of the eukaryotic genome.

    abstract::1 alpha,25(OH)2vitamin-D3, [1 alpha,25(OH)2D3] is a potent steroid hormone that produces a wide array of biologic effects in a variety of target tissues within the body through its ability to modulate gene transcription of specific target genes. Evidence for transcription regulation of a specific gene typically includ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Hannah SS,Norman AW

    更新日期:1994-11-01 00:00:00

  • Decreased dietary copper impairs vascular function.

    abstract::Vascular defects associated with dietary copper deficiency may result from altered interactions between vascular smooth muscle cells and nitric oxide. ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审



    更新日期:1993-06-01 00:00:00

  • High-fat meals and endothelial function.

    abstract::Two recent studies on the effects of single high-fat meals on endothelial function have postulated an additional mechanism by which dietary lipids can impact atherosclerosis. These studies found that dietary lipids decrease the ability of blood vessels to dilate and that this modification of endothelial function was p...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Tomaino RM,Decker EA

    更新日期:1998-06-01 00:00:00

  • Mitochondrial response to controlled nutrition in health and disease.

    abstract::Mitochondria exert crucial physiological functions that create complex links among nutrition, health, and disease. While mitochondrial dysfunction with subsequent impairment of oxidative phosphorylation (OXPHOS) is the hallmark of the rare inherited OXPHOS diseases, OXPHOS dysfunction also plays a central role in the ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Schiff M,Bénit P,Coulibaly A,Loublier S,El-Khoury R,Rustin P

    更新日期:2011-02-01 00:00:00

  • Ready-to-use therapeutic food for prevention of childhood undernutrition.

    abstract::Undernutrition is a major contributor to child mortality and total global disease burden. Ready-to-use therapeutic food (RUTF) is recommended by the World Health Organization for community-based management of uncomplicated forms of severe acute malnutrition. New research has evaluated the role of RUTF for the preventi...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Hendricks KM

    更新日期:2010-07-01 00:00:00

  • Folic acid absorption, anticonvulsant and contraceptive therapy.

    abstract::Studies of the effects of oral contraceptives and other drugs on folic acid absorption are reviewed. In 1 study, estradiol, progesterone, and estrone did not inhibit folate conjugase nor interfere with the passage of folate conjugase across the lysosomal membrane. 12 women taking an oral contraceptive (norethisteron...

    journal_title:Nutrition reviews

    pub_type: 杂志文章



    更新日期:1974-02-01 00:00:00

  • Twin pregnancies: eating for three? Maternal nutrition update.

    abstract::The incidence of multifetal pregnancies has increased, mainly because of assisted reproduction treatments. This trend is reflected in increased maternal and neonatal morbidity and mortality. While the optimum maternal nutrition and weight gain patterns for singleton pregnancies is well documented, there is a paucity o...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Roselló-Soberón ME,Fuentes-Chaparro L,Casanueva E

    更新日期:2005-09-01 00:00:00

  • Maternal folate exposure in pregnancy and childhood asthma and allergy: a systematic review.

    abstract::Adequate folate status in early pregnancy is critical to prevent congenital malformations, yet little is known about whether exposure to folate, specifically folic acid supplementation beyond the recommended dose, influences chronic health outcomes. The link between maternal folate levels and risk of childhood asthma ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Brown SB,Reeves KW,Bertone-Johnson ER

    更新日期:2014-01-01 00:00:00

  • Severity of measles in malnutrition.

    abstract::Malnourished children experience more severe measles infections at a greater frequency than well nourished children. In Africa, the mortality rate for measles infection is 25-50% in infants and young children with edematous malnutrition. There is some evidence that the altered immune responses of malnourished people...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审



    更新日期:1982-07-01 00:00:00

  • Influence of altered body weight on energy expenditure.

    abstract::Long-term metabolic studies indicate that over-feeding underfeeding to gain and lose body weight produce consistent increases and decreases in energy expenditure. These changes occur in both lean and obese subjects and cause deviations from the normal relationship between energy expenditure and metabolic body size. Th...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Kinney JM

    更新日期:1995-09-01 00:00:00

  • Fortification strategies to combat zinc and iron deficiency.

    abstract::Food fortification is an important strategy to combat iron and zinc deficiency. This review covers the basic concepts of food fortification, as well as its advantages and disadvantages. The main characteristics of the most common zinc and iron compounds used in this procedure are also analyzed. ...

    journal_title:Nutrition reviews

    pub_type: 杂志文章,评审


    authors: Salgueiro MJ,Zubillaga M,Lysionek A,Caro R,Weill R,Boccio J

    更新日期:2002-02-01 00:00:00

  • Rheumatoid arthritis and dietary interventions: systematic review of clinical trials.

    abstract:CONTEXT:The impact of various dietary interventions on rheumatoid arthritis (RA), characterized by immune-inflammatory response, has been subject to increased attention. OBJECTIVE:A systematic review was conducted to update the current knowledge on the effects of nutritional, dietary supplement, and fasting interventi...

    journal_title:Nutrition reviews

    pub_type: 杂志文章


    authors: Philippou E,Petersson SD,Rodomar C,Nikiphorou E

    更新日期:2020-06-25 00:00:00